Avanafil-Impurities | Pharmaffiliates

avanafil and its Impurities

Chemically, it is a derivative of pyrimidine and is only available as the S-enantiomer.  Avanafil is a new phosphodiesterase-5 inhibitor that is faster acting and more selective than other drugs belonging to the same class. . Reference standards of Avanafil API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

Displaying 36 results for avanafil Impurities
PA 28 44000

Avanafil - API

Avanafil


  • Catalogue No.:PA 28 44000

  • CAS :

    330784-47-9

  • Molecular Formula : C23H26ClN7O3

  • Molecular Weight : 483.95

PA 28 44510

Avanafil Deschloro Impurity

Avanafil Deschloro Impurity


  • Catalogue No.:PA 28 44510

  • CAS :

    330784-50-4

  • Molecular Formula : C23H27N7O3

  • Molecular Weight : 449.51

PA 28 44520

Avanafil Amide Analog

Avanafil Amide Analog


  • Catalogue No.:PA 28 44520

  • CAS :

    NA

  • Molecular Formula : C18H22ClN5O3

  • Molecular Weight : 391.85

PA 28 44530

Avanafil N-Methyl Analog

Avanafil N-Methyl Analog


  • Catalogue No.:PA 28 44530

  • CAS :

    NA

  • Molecular Formula : C19H24ClN5O3

  • Molecular Weight : 405.88

PA 28 44540

Avanafil N-ethyl Analog

Avanafil N-ethyl Analog


  • Catalogue No.:PA 28 44540

  • CAS :

    NA

  • Molecular Formula : C20H26ClN5O3

  • Molecular Weight : 419.91

PA 28 44550

Avanafil O-Desmethyl Analog

Avanafil O-Desmethyl Analog


  • Catalogue No.:PA 28 44550

  • CAS :

    NA

  • Molecular Formula : C22H24ClN7O3

  • Molecular Weight : 469.92

PA 28 44560

Avanafil Ethyl Ester Analog

Avanafil Ethyl Ester Analog


  • Catalogue No.:PA 28 44560

  • CAS :

    NA

  • Molecular Formula : C20H25ClN4O4

  • Molecular Weight : 420.89

PA 28 44570

Avanafil Carboxylic Acid Analog

Avanafil Carboxylic Acid Analog


  • Catalogue No.:PA 28 44570

  • CAS :

    NA

  • Molecular Formula : C18H21ClN4O4

  • Molecular Weight : 392.84

PA 28 44580

R-Avanafil

R-Avanafil


  • Catalogue No.:PA 28 44580

  • CAS :

    1638497-26-3

  • Molecular Formula : C23H26ClN7O3

  • Molecular Weight : 483.95

PA 28 44590

Avanafil Keto Analog

Avanafil Keto Analog


  • Catalogue No.:PA 28 44590

  • CAS :

    1452128-53-8

  • Molecular Formula : C18H17ClN6O3

  • Molecular Weight : 400.82

PA 28 44600

Ethyl 4-((3-chloro-4-methoxybenzyl)amino)-2-(methylsulfinyl)pyrimidine-5-carboxylate

Ethyl 4-((3-chloro-4-methoxybenzyl)amino)-2-(methylsulfinyl)pyrimidine-5-carboxylate


  • Catalogue No.:PA 28 44600

  • CAS :

    330785-82-5

  • Molecular Formula : C16H18ClN3O4S

  • Molecular Weight : 383.85

PA 28 44610

Avanafi Thiomethyl Analog

Avanafi Thiomethyl Analog


  • Catalogue No.:PA 28 44610

  • CAS :

    NA

  • Molecular Formula : C19H19ClN6O2S

  • Molecular Weight : 430.91

PA 28 44620

Avanafi Dichloro Analog

Avanafi Dichloro Analog


  • Catalogue No.:PA 28 44620

  • CAS :

    NA

  • Molecular Formula : C23H25Cl2N7O3

  • Molecular Weight : 518.4

PA 28 44630

(1,4,5,6-Tetrahydropyrimidin-2-yl)methanamine

(1,4,5,6-Tetrahydropyrimidin-2-yl)methanamine


  • Catalogue No.:PA 28 44630

  • CAS :

    759408-08-7

  • Molecular Formula : C5H11N3

  • Molecular Weight : 113.16

PA 28 44640

4-((4-((3-Chloro-4-methoxybenzyl)amino)-5-((pyrimidin-2-ylmethyl)carbamoyl)pyrimidin-2-yl)amino)-5-hydroxypentanoic Acid

4-((4-((3-Chloro-4-methoxybenzyl)amino)-5-((pyrimidin-2-ylmethyl)carbamoyl)pyrimidin-2-yl)amino)-5-hydroxypentanoic Acid


  • Catalogue No.:PA 28 44640

  • CAS :

    NA

  • Molecular Formula : C23H26ClN7O5

  • Molecular Weight : 515.95

PA 28 44650

4-((3-Chloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylic Acid

4-((3-Chloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylic Acid


  • Catalogue No.:PA 28 44650

  • CAS :

    330786-34-0

  • Molecular Formula : C14H14ClN3O3S

  • Molecular Weight : 339.8

PA 28 44660

Avanafil Isopropyl Amide Analog

Avanafil Isopropyl Amide Analog


  • Catalogue No.:PA 28 44660

  • CAS :

    NA

  • Molecular Formula : C21H28ClN5O3

  • Molecular Weight : 433.93

PA STI 009310

Avanafil-13C5,15N

Avanafil-13C5,15N


  • Catalogue No.:PA STI 009310

  • CAS :

    1276495-36-3

  • Molecular Formula : C1813C5H26ClN615NO3

  • Molecular Weight : 489.91

PA 28 44670

Avanafil Dimer

Avanafil Dimer


  • Catalogue No.:PA 28 44670

  • CAS :

    NA

  • Molecular Formula : C41H45Cl2N11O6

  • Molecular Weight : 858.78

PA 28 0441000

Ethyl 4-((2-chloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylate

Ethyl 4-((2-chloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylate


  • Catalogue No.:PA 28 0441000

  • CAS :

    NA

  • Molecular Formula : C16H18ClN3O3S

  • Molecular Weight : 367.85

PA 28 0441001

Ethyl 4-((3,5-dichloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylate

Ethyl 4-((3,5-dichloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylate


  • Catalogue No.:PA 28 0441001

  • CAS :

    NA

  • Molecular Formula : C16H17Cl2N3O3S

  • Molecular Weight : 402.29

PA 28 0441002

Ethyl 4-((3-chloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylate

Ethyl 4-((3-chloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylate


  • Catalogue No.:PA 28 0441002

  • CAS :

    330785-99-4

  • Molecular Formula : C15H16ClN3O4

  • Molecular Weight : 337.76

PA 28 0441003

Avanafil

Avanafil


  • Catalogue No.:PA 28 0441003

  • CAS :

    1364671-62-4

  • Molecular Formula : C19H19ClN6O2S

  • Molecular Weight : 430.91

PA 28 0441004

(S)-Ethyl 4-(3-chloro-4-methoxybenzylamino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylate

(S)-Ethyl 4-(3-chloro-4-methoxybenzylamino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylate


  • Catalogue No.:PA 28 0441004

  • CAS :

    330785-83-6

  • Molecular Formula : C20H25ClN4O4

  • Molecular Weight : 420.89

PA 28 0441005

(S)-4-((3-Chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)-N-((1,4,5,6-tetrahydropyrimidin-2-yl)methyl)pyrimidine-5-carboxamide

(S)-4-((3-Chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)-N-((1,4,5,6-tetrahydropyrimidin-2-yl)methyl)pyrimidine-5-carboxamide


  • Catalogue No.:PA 28 0441005

  • CAS :

    NA

  • Molecular Formula : C23H30ClN7O3

  • Molecular Weight : 487.99

PA 28 0441006

(S)-4-((3-Chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)-N,N-bis(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide

(S)-4-((3-Chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)-N,N-bis(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide


  • Catalogue No.:PA 28 0441006

  • CAS :

    NA

  • Molecular Formula : C28H30ClN9O3

  • Molecular Weight : 576.06

PA 28 0441007

(R)-2-(2-(Hydroxymethyl)pyrrolidin-1-yl)-4-((4-methoxybenzyl)amino)-N-(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide

(R)-2-(2-(Hydroxymethyl)pyrrolidin-1-yl)-4-((4-methoxybenzyl)amino)-N-(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide


  • Catalogue No.:PA 28 0441007

  • CAS :

    2250242-21-6

  • Molecular Formula : C23H27N7O3

  • Molecular Weight : 449.52

PA 28 0441008

1H-Benzo[d][1,2,3]triazol-1-yl (S)-4-((3-chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylate

1H-Benzo[d][1,2,3]triazol-1-yl (S)-4-((3-chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylate


  • Catalogue No.:PA 28 0441008

  • CAS :

    NA

  • Molecular Formula : C24H24ClN7O4

  • Molecular Weight : 509.95

PA 28 0441009

4-((3-Chloro-4-methoxybenzyl)amino)-2-((S)-2-(((4-((3-chloro-4-methoxybenzyl)amino)-2-((S)-2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carbonyl)oxy)methyl)pyrrolidin-1-yl)pyrimidine-5-carboxylic acid

4-((3-Chloro-4-methoxybenzyl)amino)-2-((S)-2-(((4-((3-chloro-4-methoxybenzyl)amino)-2-((S)-2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carbonyl)oxy)methyl)pyrrolidin-1-yl)pyrimidine-5-carboxylic acid


  • Catalogue No.:PA 28 0441009

  • CAS :

    NA

  • Molecular Formula : C36H40Cl2N8O7

  • Molecular Weight : 767.67

PA 28 0441010

(S)-4-((3-Chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)-N-isopropyl-N-(isopropylcarbamoyl)pyrimidine-5-carboxamide

(S)-4-((3-Chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)-N-isopropyl-N-(isopropylcarbamoyl)pyrimidine-5-carboxamide


  • Catalogue No.:PA 28 0441010

  • CAS :

    NA

  • Molecular Formula : C25H35ClN6O4

  • Molecular Weight : 519.04

PA 28 0441011

Ethyl (S)-4-((3,5-dichloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylate

Ethyl (S)-4-((3,5-dichloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylate


  • Catalogue No.:PA 28 0441011

  • CAS :

    NA

  • Molecular Formula : C20H24Cl2N4O4

  • Molecular Weight : 455.34

PA 28 0441012

 (S)-4-((3,5-Dichloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylic acid

(S)-4-((3,5-Dichloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylic acid


  • Catalogue No.:PA 28 0441012

  • CAS :

    1643811-26-0

  • Molecular Formula : C18H20Cl2N4O4

  • Molecular Weight : 427.28

PA 28 0441013

 Ethyl (S)-4-((2-chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylate

Ethyl (S)-4-((2-chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylate


  • Catalogue No.:PA 28 0441013

  • CAS :

    NA

  • Molecular Formula : C20H25ClN4O4

  • Molecular Weight : 420.89

PA 28 0441014

4-((3-Chloro-4-methoxybenzyl)amino)-2-(methylsulfinyl)-N-(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide

4-((3-Chloro-4-methoxybenzyl)amino)-2-(methylsulfinyl)-N-(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide


  • Catalogue No.:PA 28 0441014

  • CAS :

    1364671-52-2

  • Molecular Formula : C19H19ClN6O3S

  • Molecular Weight : 446.91

PA STI 089027

Avanafil D4

Avanafil D4


  • Catalogue No.:PA STI 089027

  • CAS :

    2012598-68-2

  • Molecular Formula : C23H22D4ClN7O3

  • Molecular Weight : 487.98

PA 28 0441015

Avanafil Diamine Impurity

Avanafil Diamine Impurity


  • Catalogue No.:PA 28 0441015

  • CAS :

    1643811-29-3

  • Molecular Formula : C26H25Cl2N7O3

  • Molecular Weight : 554.43