avanafil and its Impurities

Chemically, it is a derivative of pyrimidine and is only available as the S-enantiomer.  Avanafil is a new phosphodiesterase-5 inhibitor that is faster acting and more selective than other drugs belonging to the same class. . Reference standards of Avanafil API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

Displaying 47 results for avanafil Impurities
PA 28 44000

Avanafil

Avanafil

  • Catalogue No.:PA 28 44000

  • CAS :

    330784-47-9

  • Molecular Formula : C23H26ClN7O3

  • Molecular Weight : 483.95

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PA 28 44510

Avanafil Deschloro Impurity

Avanafil Deschloro Impurity

  • Catalogue No.:PA 28 44510

  • CAS :

    330784-50-4

  • Molecular Formula : C23H27N7O3

  • Molecular Weight : 449.51

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PA 28 44520

Avanafil Amide Analog

Avanafil Amide Analog

  • Catalogue No.:PA 28 44520

  • CAS :

    372117-54-9

  • Molecular Formula : C18H22ClN5O3

  • Molecular Weight : 391.85

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PA 28 44530

Avanafil N-Methyl Analog

Avanafil N-Methyl Analog

  • Catalogue No.:PA 28 44530

  • CAS :

    372117-53-8

  • Molecular Formula : C19H24ClN5O3

  • Molecular Weight : 405.88

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PA 28 44540

Avanafil N-ethyl Analog

Avanafil N-ethyl Analog

  • Catalogue No.:PA 28 44540

  • CAS :

    2520114-39-8

  • Molecular Formula : C20H26ClN5O3

  • Molecular Weight : 419.91

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PA 28 44550

Avanafil O-Desmethyl Analog

Avanafil O-Desmethyl Analog

  • Catalogue No.:PA 28 44550

  • CAS :

    330785-05-2

  • Molecular Formula : C22H24ClN7O3

  • Molecular Weight : 469.92

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PA 28 44560

Avanafil Ethyl Ester Analog

Avanafil Ethyl Ester Analog

  • Catalogue No.:PA 28 44560

  • CAS :

    1638497-22-9

  • Molecular Formula : C20H25ClN4O4

  • Molecular Weight : 420.89

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PA 28 44570

Avanafil Carboxylic Acid Analog

Avanafil Carboxylic Acid Analog

  • Catalogue No.:PA 28 44570

  • CAS :

    1638497-25-2

  • Molecular Formula : C18H21ClN4O4

  • Molecular Weight : 392.84

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PA 28 44580

R-Avanafil

R-Avanafil

  • Catalogue No.:PA 28 44580

  • CAS :

    1638497-26-3

  • Molecular Formula : C23H26ClN7O3

  • Molecular Weight : 483.95

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PA 28 44590

Avanafil Keto Analog

Avanafil Keto Analog

  • Catalogue No.:PA 28 44590

  • CAS :

    1452128-53-8

  • Molecular Formula : C18H17ClN6O3

  • Molecular Weight : 400.82

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PA 28 44600

Ethyl 4-((3-chloro-4-methoxybenzyl)amino)-2-(methylsulfinyl)pyrimidine-5-carboxylate

Ethyl 4-((3-chloro-4-methoxybenzyl)amino)-2-(methylsulfinyl)pyrimidine-5-carboxylate

  • Catalogue No.:PA 28 44600

  • CAS :

    330785-82-5

  • Molecular Formula : C16H18ClN3O4S

  • Molecular Weight : 383.85

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PA 28 44610

Avanafi Thiomethyl Analog

Avanafi Thiomethyl Analog

  • Catalogue No.:PA 28 44610

  • CAS :

    1364671-62-4

  • Molecular Formula : C19H19ClN6O2S

  • Molecular Weight : 430.91

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PA 28 44620

Avanafi Dichloro Analog

Avanafi Dichloro Analog

  • Catalogue No.:PA 28 44620

  • CAS :

    2520113-66-8

  • Molecular Formula : C23H25Cl2N7O3

  • Molecular Weight : 518.4

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PA 28 44630

(1,4,5,6-Tetrahydropyrimidin-2-yl)methanamine

(1,4,5,6-Tetrahydropyrimidin-2-yl)methanamine

  • Catalogue No.:PA 28 44630

  • CAS :

    759408-08-7

  • Molecular Formula : C5H11N3

  • Molecular Weight : 113.16

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PA 28 44640

4-((4-((3-Chloro-4-methoxybenzyl)amino)-5-((pyrimidin-2-ylmethyl)carbamoyl)pyrimidin-2-yl)amino)-5-hydroxypentanoic Acid

4-((4-((3-Chloro-4-methoxybenzyl)amino)-5-((pyrimidin-2-ylmethyl)carbamoyl)pyrimidin-2-yl)amino)-5-hydroxypentanoic Acid

  • Catalogue No.:PA 28 44640

  • CAS :

    2748151-94-0

  • Molecular Formula : C23H26ClN7O5

  • Molecular Weight : 515.95

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PA 28 44650

4-((3-Chloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylic Acid

4-((3-Chloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylic Acid

  • Catalogue No.:PA 28 44650

  • CAS :

    330786-34-0

  • Molecular Formula : C14H14ClN3O3S

  • Molecular Weight : 339.8

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PA 28 44660

Avanafil Isopropyl Amide Analog

Avanafil Isopropyl Amide Analog

  • Catalogue No.:PA 28 44660

  • CAS :

    2520114-11-6

  • Molecular Formula : C21H28ClN5O3

  • Molecular Weight : 433.93

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PA STI 009310

Avanafil-13C5,15N

Avanafil-13C5,15N

  • Catalogue No.:PA STI 009310

  • CAS :

    1276495-36-3

  • Molecular Formula : C1813C5H26ClN615NO3

  • Molecular Weight : 489.91

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PA 28 44670

Avanafil Dimer

Avanafil Dimer

  • Catalogue No.:PA 28 44670

  • CAS :

    1643811-27-1

  • Molecular Formula : C41H45Cl2N11O6

  • Molecular Weight : 858.78

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PA 28 0441000

Ethyl 4-((2-chloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylate

Ethyl 4-((2-chloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylate

  • Catalogue No.:PA 28 0441000

  • CAS :

    2520114-23-0

  • Molecular Formula : C16H18ClN3O3S

  • Molecular Weight : 367.85

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PA 28 0441001

Ethyl 4-((3,5-dichloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylate

Ethyl 4-((3,5-dichloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylate

  • Catalogue No.:PA 28 0441001

  • CAS :

    2250242-48-7

  • Molecular Formula : C16H17Cl2N3O3S

  • Molecular Weight : 402.29

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PA 28 0441002

Ethyl 4-((3-chloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylate

Ethyl 4-((3-chloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylate

  • Catalogue No.:PA 28 0441002

  • CAS :

    330785-99-4

  • Molecular Formula : C15H16ClN3O4

  • Molecular Weight : 337.76

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PA 28 0441004

(S)-Ethyl 4-(3-chloro-4-methoxybenzylamino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylate

(S)-Ethyl 4-(3-chloro-4-methoxybenzylamino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylate

  • Catalogue No.:PA 28 0441004

  • CAS :

    330785-83-6

  • Molecular Formula : C20H25ClN4O4

  • Molecular Weight : 420.89

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PA 28 0441005

(S)-4-((3-Chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)-N-((1,4,5,6-tetrahydropyrimidin-2-yl)methyl)pyrimidine-5-carboxamide

(S)-4-((3-Chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)-N-((1,4,5,6-tetrahydropyrimidin-2-yl)methyl)pyrimidine-5-carboxamide

  • Catalogue No.:PA 28 0441005

  • CAS :

    2520113-69-1

  • Molecular Formula : C23H30ClN7O3

  • Molecular Weight : 487.99

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PA 28 0441006

(S)-4-((3-Chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)-N,N-bis(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide

(S)-4-((3-Chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)-N,N-bis(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide

  • Catalogue No.:PA 28 0441006

  • CAS :

    NA

  • Molecular Formula : C28H30ClN9O3

  • Molecular Weight : 576.06

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PA 28 0441007

(R)-2-(2-(Hydroxymethyl)pyrrolidin-1-yl)-4-((4-methoxybenzyl)amino)-N-(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide

(R)-2-(2-(Hydroxymethyl)pyrrolidin-1-yl)-4-((4-methoxybenzyl)amino)-N-(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide

  • Catalogue No.:PA 28 0441007

  • CAS :

    2250242-21-6

  • Molecular Formula : C23H27N7O3

  • Molecular Weight : 449.52

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PA 28 0441008

1H-Benzo[d][1,2,3]triazol-1-yl (S)-4-((3-chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylate

1H-Benzo[d][1,2,3]triazol-1-yl (S)-4-((3-chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylate

  • Catalogue No.:PA 28 0441008

  • CAS :

    2520113-98-6

  • Molecular Formula : C24H24ClN7O4

  • Molecular Weight : 509.95

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PA 28 0441009

4-((3-Chloro-4-methoxybenzyl)amino)-2-((S)-2-(((4-((3-chloro-4-methoxybenzyl)amino)-2-((S)-2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carbonyl)oxy)methyl)pyrrolidin-1-yl)pyrimidine-5-carboxylic acid

4-((3-Chloro-4-methoxybenzyl)amino)-2-((S)-2-(((4-((3-chloro-4-methoxybenzyl)amino)-2-((S)-2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carbonyl)oxy)methyl)pyrrolidin-1-yl)pyrimidine-5-carboxylic acid

  • Catalogue No.:PA 28 0441009

  • CAS :

    2520114-03-6

  • Molecular Formula : C36H40Cl2N8O7

  • Molecular Weight : 767.67

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PA 28 0441010

(S)-4-((3-Chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)-N-isopropyl-N-(isopropylcarbamoyl)pyrimidine-5-carboxamide

(S)-4-((3-Chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)-N-isopropyl-N-(isopropylcarbamoyl)pyrimidine-5-carboxamide

  • Catalogue No.:PA 28 0441010

  • CAS :

    2520114-17-2

  • Molecular Formula : C25H35ClN6O4

  • Molecular Weight : 519.04

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PA 28 0441011

Ethyl (S)-4-((3,5-dichloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylate

Ethyl (S)-4-((3,5-dichloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylate

  • Catalogue No.:PA 28 0441011

  • CAS :

    2520114-19-4

  • Molecular Formula : C20H24Cl2N4O4

  • Molecular Weight : 455.34

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PA 28 0441012

 (S)-4-((3,5-Dichloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylic acid

(S)-4-((3,5-Dichloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylic acid

  • Catalogue No.:PA 28 0441012

  • CAS :

    1643811-26-0

  • Molecular Formula : C18H20Cl2N4O4

  • Molecular Weight : 427.28

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PA 28 0441013

 Ethyl (S)-4-((2-chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylate

Ethyl (S)-4-((2-chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylate

  • Catalogue No.:PA 28 0441013

  • CAS :

    2520114-28-5

  • Molecular Formula : C20H25ClN4O4

  • Molecular Weight : 420.89

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PA 28 0441014

4-((3-Chloro-4-methoxybenzyl)amino)-2-(methylsulfinyl)-N-(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide

4-((3-Chloro-4-methoxybenzyl)amino)-2-(methylsulfinyl)-N-(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide

  • Catalogue No.:PA 28 0441014

  • CAS :

    1364671-52-2

  • Molecular Formula : C19H19ClN6O3S

  • Molecular Weight : 446.91

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PA STI 089027

Avanafil D4

Avanafil D4

  • Catalogue No.:PA STI 089027

  • CAS :

    2012598-68-2

  • Molecular Formula : C23H22D4ClN7O3

  • Molecular Weight : 487.98

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PA 28 0441015

Avanafil Diamine Impurity

Avanafil Diamine Impurity

  • Catalogue No.:PA 28 0441015

  • CAS :

    1643811-29-3

  • Molecular Formula : C26H25Cl2N7O3

  • Molecular Weight : 554.43

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PA 28 0441016

(3,5-Dichloro-4-methoxyphenyl)methanamine Hydrochloride

(3,5-Dichloro-4-methoxyphenyl)methanamine Hydrochloride

  • Catalogue No.:PA 28 0441016

  • CAS :

    38057-59-9

  • Molecular Formula : C8H10Cl3NO

  • Molecular Weight : 242.52

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PA 28 0441017

(S)-4-((3-Chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylic Acid

(S)-4-((3-Chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylic Acid

  • Catalogue No.:PA 28 0441017

  • CAS :

    330785-84-7

  • Molecular Formula : C18H21ClN4O4

  • Molecular Weight : 392.84

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PA 28 0441018

4-(Diethylamino)-4'-sulfoazobenzene

4-(Diethylamino)-4'-sulfoazobenzene

  • Catalogue No.:PA 28 0441018

  • CAS :

    6287-12-3

  • Molecular Formula : C16H19N3O3S

  • Molecular Weight : 333.41

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PA 28 0441019

(S)-4-((3-Chloro-4-methoxybenzyl)(nitroso)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)-N-(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide

(S)-4-((3-Chloro-4-methoxybenzyl)(nitroso)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)-N-(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide

  • Catalogue No.:PA 28 0441019

  • CAS :

    3050754-67-8

  • Molecular Formula : C23H25ClN8O4

  • Molecular Weight : 512.96

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PA 28 0441020

(1-(4-((3-Chloro-4-methoxybenzyl)amino)-5-((pyrimidin-2-ylmethyl)carbamoyl)pyrimidin-2-yl)pyrrolidin-2-yl)methyl 4-((3-chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylate

(1-(4-((3-Chloro-4-methoxybenzyl)amino)-5-((pyrimidin-2-ylmethyl)carbamoyl)pyrimidin-2-yl)pyrrolidin-2-yl)methyl 4-((3-chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylate

  • Catalogue No.:PA 28 0441020

  • CAS :

    NA

  • Molecular Formula : C41H45Cl2N11O6

  • Molecular Weight : 858.78

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PA 28 0441021

(S)-4-((3-Chloro-4-methoxybenzyl)(nitroso)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxamide

(S)-4-((3-Chloro-4-methoxybenzyl)(nitroso)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxamide

  • Catalogue No.:PA 28 0441021

  • CAS :

    NA

  • Molecular Formula : C18H21ClN6O4

  • Molecular Weight : 420.85

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PA 28 0441022

4-((3-Chloro-4-methoxybenzyl)(nitroso)amino)-2-(methylthio)-N-(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide

4-((3-Chloro-4-methoxybenzyl)(nitroso)amino)-2-(methylthio)-N-(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide

  • Catalogue No.:PA 28 0441022

  • CAS :

    NA

  • Molecular Formula : C19H18ClN7O3S

  • Molecular Weight : 459.91

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PA 28 0441023

Ethyl (S)-4-((3-chloro-4-methoxybenzyl)(nitroso)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylate

Ethyl (S)-4-((3-chloro-4-methoxybenzyl)(nitroso)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylate

  • Catalogue No.:PA 28 0441023

  • CAS :

    NA

  • Molecular Formula : C20H24ClN5O5

  • Molecular Weight : 449.89

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PA 28 0441024

((S)-1-(4-((3-Chloro-4-methoxybenzyl)amino)-5-((pyrimidin-2-ylmethyl)carbamoyl)pyrimidin-2-yl)pyrrolidin-2-yl)methyl 4-((3-chloro-4-methoxybenzyl)(nitroso)amino)-2-((S)-2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylate

((S)-1-(4-((3-Chloro-4-methoxybenzyl)amino)-5-((pyrimidin-2-ylmethyl)carbamoyl)pyrimidin-2-yl)pyrrolidin-2-yl)methyl 4-((3-chloro-4-methoxybenzyl)(nitroso)amino)-2-((S)-2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylate

  • Catalogue No.:PA 28 0441024

  • CAS :

    NA

  • Molecular Formula : C41H44Cl2N12O7

  • Molecular Weight : 887.78

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PA 28 0441025

((S)-1-(4-((3-Chloro-4-methoxybenzyl)(nitroso)amino)-5-((pyrimidin-2-ylmethyl)carbamoyl)pyrimidin-2-yl)pyrrolidin-2-yl)methyl 4-((3-chloro-4-methoxybenzyl)amino)-2-((S)-2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylate

((S)-1-(4-((3-Chloro-4-methoxybenzyl)(nitroso)amino)-5-((pyrimidin-2-ylmethyl)carbamoyl)pyrimidin-2-yl)pyrrolidin-2-yl)methyl 4-((3-chloro-4-methoxybenzyl)amino)-2-((S)-2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylate

  • Catalogue No.:PA 28 0441025

  • CAS :

    NA

  • Molecular Formula : C41H44Cl2N12O7

  • Molecular Weight : 887.78

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PA 28 0441026

Ethyl 4-((3-chloro-4-methoxybenzyl)(nitroso)amino)-2-(methylthio)pyrimidine-5-carboxylate

Ethyl 4-((3-chloro-4-methoxybenzyl)(nitroso)amino)-2-(methylthio)pyrimidine-5-carboxylate

  • Catalogue No.:PA 28 0441026

  • CAS :

    NA

  • Molecular Formula : C16H17ClN4O4S

  • Molecular Weight : 396.85

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PA 28 0441027

Ethyl 4-((3-chloro-4-methoxybenzyl)(nitroso)amino)-2-(methylsulfinyl)pyrimidine-5-carboxylate

Ethyl 4-((3-chloro-4-methoxybenzyl)(nitroso)amino)-2-(methylsulfinyl)pyrimidine-5-carboxylate

  • Catalogue No.:PA 28 0441027

  • CAS :

    NA

  • Molecular Formula : C16H17ClN4O5S

  • Molecular Weight : 412.85

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