Avatrombopag, sold under the brand name Doptelet, is a medication that used for certain conditions.lead to thrombocytopenia (low platelets) such as thrombocytopenia associated with chronic liver disease. Reference standards of Avatrombopag API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
Avatrombopag
Catalogue No.:PA 01 2990000
CAS :
Molecular Formula : C29H34Cl2N6O3S2
Molecular Weight : 649.65
1-(3-Chloro-5-((4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl-2,2,3,3,5,5,6,6-d8)thiazol-2-yl)carbamoyl)pyridin-2-yl)piperidine-4-carboxylic acid
Catalogue No.:PA STI 088916
Molecular Formula : C29H26D8Cl2N6O3S2
Molecular Weight : 657.7
6-(4-Carboxypiperidin-1-yl)-5-chloronicotinic Acid
Catalogue No.:PA 01 2991000
Molecular Formula : C12H13ClN2O4
Molecular Weight : 284.7
1-(5-((4-(5-Bromo-4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-yl)carbamoyl)-3-chloropyridin-2-yl)piperidine-4-carboxylic Acid
Catalogue No.:PA 01 2991001
Molecular Formula : C29H33BrCl2N6O3S2
Molecular Weight : 728.55
5-Bromo-4-(5-bromo-4-chlorothiophen-2-yl)thiazol-2-amine
Catalogue No.:PA 01 2991002
Molecular Formula : C7H3Br2ClN2S2
Molecular Weight : 374.49
4-(5-Bromo-4-chlorothiophen-2-yl)thiazol-2-amine
Catalogue No.:PA 01 2991003
Molecular Formula : C7H4BrClN2S2
Molecular Weight : 295.6
5-Bromo-4-(thiophen-2-yl)thiazol-2-amine
Catalogue No.:PA 01 2991004
Molecular Formula : C7H5BrN2S2
Molecular Weight : 261.16
5-Bromo-4-(5-chlorothiophen-2-yl)thiazol-2-amine
Catalogue No.:PA 01 2991005
4-(5-Chloro-2-thienyl)-1,3-thiazol-2-amine
Catalogue No.:PA 01 2991006
Molecular Formula : C7H5ClN2S2
Molecular Weight : 216.7
4-(Thiophen-2-yl)thiazol-2-amine
Catalogue No.:PA 01 2991007
Molecular Formula : C7H6N2S2
Molecular Weight : 182.26
4-(2-(6-(4-Carboxypiperidin-1-yl)-5-chloronicotinamido)-4-(4-chlorothiophen-2-yl)thiazol-5-yl)-1-cyclohexylpiperazine 1-oxide
Catalogue No.:PA 01 2991013
Molecular Formula : C29H34Cl2N6O4S2
Molecular Weight : 665.65
5-Chloro-N-(4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-yl)-6-(dimethylamino)nicotinamide
Catalogue No.:PA 01 2991008
Molecular Formula : C25H30Cl2N6OS2
Molecular Weight : 565.58
4-(4-Chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-amine
Catalogue No.:PA 01 2991009
Molecular Formula : C17H23ClN4S2
Molecular Weight : 382.97
Avatrombopag Ester Impurity
Catalogue No.:PA 01 2991010
Molecular Formula : C31H38Cl2N6O3S2
Molecular Weight : 677.7
Ethyl 1-ethylpiperidine-4-carboxylate
Catalogue No.:PA 01 2991011
Molecular Formula : C10H19NO2
Molecular Weight : 185.27
5,6-Dichloro-N-(4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-yl)nicotinamide
Catalogue No.:PA 01 2991012
Molecular Formula : C23H24Cl3N5OS2
Molecular Weight : 556.95
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