Avatrombopag and its Impurities

Avatrombopag, sold under the brand name Doptelet, is a medication that used for certain conditions.lead to thrombocytopenia (low platelets) such as thrombocytopenia associated with chronic liver disease. Reference standards of Avatrombopag API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

Displaying 32 results for Avatrombopag Impurities
Drug Reference Standards & Impurity Synthesis in India
PA 01 2990000

Avatrombopag

Avatrombopag

  • Catalogue No.:PA 01 2990000

  • CAS :

    570406-98-3

  • Molecular Formula : C29H34Cl2N6O3S2

  • Molecular Weight : 649.65

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Drug Reference Standards & Impurity Synthesis in India
PA STI 088916

1-(3-Chloro-5-((4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl-2,2,3,3,5,5,6,6-d8)thiazol-2-yl)carbamoyl)pyridin-2-yl)piperidine-4-carboxylic acid

1-(3-Chloro-5-((4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl-2,2,3,3,5,5,6,6-d8)thiazol-2-yl)carbamoyl)pyridin-2-yl)piperidine-4-carboxylic acid

  • Catalogue No.:PA STI 088916

  • CAS :

    NA

  • Molecular Formula : C29H26D8Cl2N6O3S2

  • Molecular Weight : 657.7

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Drug Reference Standards & Impurity Synthesis in India
PA 01 2991000

6-(4-Carboxypiperidin-1-yl)-5-chloronicotinic Acid

6-(4-Carboxypiperidin-1-yl)-5-chloronicotinic Acid

  • Catalogue No.:PA 01 2991000

  • CAS :

    958457-83-5

  • Molecular Formula : C12H13ClN2O4

  • Molecular Weight : 284.7

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Drug Reference Standards & Impurity Synthesis in India
PA 01 2991001

1-(5-((4-(5-Bromo-4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-yl)carbamoyl)-3-chloropyridin-2-yl)piperidine-4-carboxylic Acid

1-(5-((4-(5-Bromo-4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-yl)carbamoyl)-3-chloropyridin-2-yl)piperidine-4-carboxylic Acid

  • Catalogue No.:PA 01 2991001

  • CAS :

    NA

  • Molecular Formula : C29H33BrCl2N6O3S2

  • Molecular Weight : 728.55

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Drug Reference Standards & Impurity Synthesis in India
PA 01 2991002

5-Bromo-4-(5-bromo-4-chlorothiophen-2-yl)thiazol-2-amine

5-Bromo-4-(5-bromo-4-chlorothiophen-2-yl)thiazol-2-amine

  • Catalogue No.:PA 01 2991002

  • CAS :

    2401867-89-6

  • Molecular Formula : C7H3Br2ClN2S2

  • Molecular Weight : 374.49

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Drug Reference Standards & Impurity Synthesis in India
PA 01 2991003

4-(5-Bromo-4-chlorothiophen-2-yl)thiazol-2-amine

4-(5-Bromo-4-chlorothiophen-2-yl)thiazol-2-amine

  • Catalogue No.:PA 01 2991003

  • CAS :

    1534575-19-3

  • Molecular Formula : C7H4BrClN2S2

  • Molecular Weight : 295.6

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Drug Reference Standards & Impurity Synthesis in India
PA 01 2991004

5-Bromo-4-(thiophen-2-yl)thiazol-2-amine

5-Bromo-4-(thiophen-2-yl)thiazol-2-amine

  • Catalogue No.:PA 01 2991004

  • CAS :

    81216-84-4

  • Molecular Formula : C7H5BrN2S2

  • Molecular Weight : 261.16

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Drug Reference Standards & Impurity Synthesis in India
PA 01 2991005

5-Bromo-4-(5-chlorothiophen-2-yl)thiazol-2-amine

5-Bromo-4-(5-chlorothiophen-2-yl)thiazol-2-amine

  • Catalogue No.:PA 01 2991005

  • CAS :

    1268118-96-2

  • Molecular Formula : C7H4BrClN2S2

  • Molecular Weight : 295.6

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Drug Reference Standards & Impurity Synthesis in India
PA 01 2991006

4-(5-Chloro-2-thienyl)-1,3-thiazol-2-amine

4-(5-Chloro-2-thienyl)-1,3-thiazol-2-amine

  • Catalogue No.:PA 01 2991006

  • CAS :

    123971-45-9

  • Molecular Formula : C7H5ClN2S2

  • Molecular Weight : 216.7

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Drug Reference Standards & Impurity Synthesis in India
PA 01 2991007

4-(Thiophen-2-yl)thiazol-2-amine

4-(Thiophen-2-yl)thiazol-2-amine

  • Catalogue No.:PA 01 2991007

  • CAS :

    28989-50-6

  • Molecular Formula : C7H6N2S2

  • Molecular Weight : 182.26

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Drug Reference Standards & Impurity Synthesis in India
PA 01 2991013

4-(2-(6-(4-Carboxypiperidin-1-yl)-5-chloronicotinamido)-4-(4-chlorothiophen-2-yl)thiazol-5-yl)-1-cyclohexylpiperazine 1-oxide

4-(2-(6-(4-Carboxypiperidin-1-yl)-5-chloronicotinamido)-4-(4-chlorothiophen-2-yl)thiazol-5-yl)-1-cyclohexylpiperazine 1-oxide

  • Catalogue No.:PA 01 2991013

  • CAS :

    2681355-40-6

  • Molecular Formula : C29H34Cl2N6O4S2

  • Molecular Weight : 665.65

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Drug Reference Standards & Impurity Synthesis in India
PA 01 2991008

5-Chloro-N-(4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-yl)-6-(dimethylamino)nicotinamide

5-Chloro-N-(4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-yl)-6-(dimethylamino)nicotinamide

  • Catalogue No.:PA 01 2991008

  • CAS :

    2626934-45-8

  • Molecular Formula : C25H30Cl2N6OS2

  • Molecular Weight : 565.58

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Drug Reference Standards & Impurity Synthesis in India
PA 01 2991009

4-(4-Chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-amine

4-(4-Chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-amine

  • Catalogue No.:PA 01 2991009

  • CAS :

    570407-64-6

  • Molecular Formula : C17H23ClN4S2

  • Molecular Weight : 382.97

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Drug Reference Standards & Impurity Synthesis in India
PA 01 2991010

Avatrombopag Ester Impurity

Avatrombopag Ester Impurity

  • Catalogue No.:PA 01 2991010

  • CAS :

    570403-14-4

  • Molecular Formula : C31H38Cl2N6O3S2

  • Molecular Weight : 677.7

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Drug Reference Standards & Impurity Synthesis in India
PA 01 2991011

Ethyl 1-ethylpiperidine-4-carboxylate

Ethyl 1-ethylpiperidine-4-carboxylate

  • Catalogue No.:PA 01 2991011

  • CAS :

    24252-38-8

  • Molecular Formula : C10H19NO2

  • Molecular Weight : 185.27

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Drug Reference Standards & Impurity Synthesis in India
PA 01 2991012

5,6-Dichloro-N-(4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-yl)nicotinamide

5,6-Dichloro-N-(4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-yl)nicotinamide

  • Catalogue No.:PA 01 2991012

  • CAS :

    570403-04-2

  • Molecular Formula : C23H24Cl3N5OS2

  • Molecular Weight : 556.95

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Drug Reference Standards & Impurity Synthesis in India
PA 01 2991014

1-(3-Chloro-5-((5-(4-cyclohexylpiperazin-1-yl)-4-(4,5-dichlorothiophen-2-yl)thiazol-2-yl)carbamoyl)pyridin-2-yl)piperidine-4-carboxylic Acid

1-(3-Chloro-5-((5-(4-cyclohexylpiperazin-1-yl)-4-(4,5-dichlorothiophen-2-yl)thiazol-2-yl)carbamoyl)pyridin-2-yl)piperidine-4-carboxylic Acid

  • Catalogue No.:PA 01 2991014

  • CAS :

    NA

  • Molecular Formula : C29H33Cl3N6O3S2

  • Molecular Weight : 684.09

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Drug Reference Standards & Impurity Synthesis in India
PA 01 2991015

4-(4-Chlorothiophen-2-yl)thiazol-2-amine

4-(4-Chlorothiophen-2-yl)thiazol-2-amine

  • Catalogue No.:PA 01 2991015

  • CAS :

    570407-10-2

  • Molecular Formula : C7H5ClN2S2

  • Molecular Weight : 216.7

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Drug Reference Standards & Impurity Synthesis in India
PA 01 2991016

4-(3-Chlorothiophen-2-yl)thiazol-2-amine

4-(3-Chlorothiophen-2-yl)thiazol-2-amine

  • Catalogue No.:PA 01 2991016

  • CAS :

    339114-12-4

  • Molecular Formula : C7H5ClN2S2

  • Molecular Weight : 216.7

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Drug Reference Standards & Impurity Synthesis in India
PA 01 2991017

Avatrombopag Diamide Impurity

Avatrombopag Diamide Impurity

  • Catalogue No.:PA 01 2991017

  • CAS :

    2948773-23-5

  • Molecular Formula : C46H55Cl3N10O2S4

  • Molecular Weight : 1014.6

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Drug Reference Standards & Impurity Synthesis in India
PA 01 2991019

Avatrombopag 5-Chloro Acid Impurity

Avatrombopag 5-Chloro Acid Impurity

  • Catalogue No.:PA 01 2991019

  • CAS :

    NA

  • Molecular Formula : C29H34Cl2N6O3S2

  • Molecular Weight : 649.65

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Drug Reference Standards & Impurity Synthesis in India
PA 01 2991018

1-(3-Chloro-5-((4-(4-chlorothiophen-2-yl)-5-(4-nitrosopiperazin-1-yl)thiazol-2-yl)carbamoyl)pyridin-2-yl)piperidine-4-carboxylic Acid

1-(3-Chloro-5-((4-(4-chlorothiophen-2-yl)-5-(4-nitrosopiperazin-1-yl)thiazol-2-yl)carbamoyl)pyridin-2-yl)piperidine-4-carboxylic Acid

  • Catalogue No.:PA 01 2991018

  • CAS :

    NA

  • Molecular Formula : C23H23Cl2N7O4S2

  • Molecular Weight : 596.5

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Drug Reference Standards & Impurity Synthesis in India
PA 01 2991020

Avatrombopag Bromo Acid Impurity

Avatrombopag Bromo Acid Impurity

  • Catalogue No.:PA 01 2991020

  • CAS :

    2883585-26-8

  • Molecular Formula : C29H33BrCl2N6O3S2

  • Molecular Weight : 728.55

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Drug Reference Standards & Impurity Synthesis in India
PA 01 2991021

1-(2-(6-(4-Carboxypiperidin-1-yl)-5-chloronicotinamido)-4-(4-chlorothiophen-2-yl)thiazol-5-yl)-4-cyclohexylpiperazine 1-oxide

1-(2-(6-(4-Carboxypiperidin-1-yl)-5-chloronicotinamido)-4-(4-chlorothiophen-2-yl)thiazol-5-yl)-4-cyclohexylpiperazine 1-oxide

  • Catalogue No.:PA 01 2991021

  • CAS :

    NA

  • Molecular Formula : C29H34Cl2N6O4S2

  • Molecular Weight : 665.65

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Drug Reference Standards & Impurity Synthesis in India
PA 01 2991022

1-Cyclohexylpiperazine

1-Cyclohexylpiperazine

  • Catalogue No.:PA 01 2991022

  • CAS :

    17766-28-8

  • Molecular Formula : C10H20N2

  • Molecular Weight : 168.28

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Drug Reference Standards & Impurity Synthesis in India
PA 01 2991023

N1,N2-Bis(4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-yl)oxalamide

N1,N2-Bis(4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-yl)oxalamide

  • Catalogue No.:PA 01 2991023

  • CAS :

    NA

  • Molecular Formula : C36H44Cl2N8O2S4

  • Molecular Weight : 819.94

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Drug Reference Standards & Impurity Synthesis in India
PA 01 2991024

1-(3-Chloro-5-((4-(4-chlorothiophen-2-yl)thiazol-2-yl)carbamoyl)pyridin-2-yl)piperidine-4-carboxylic Acid

1-(3-Chloro-5-((4-(4-chlorothiophen-2-yl)thiazol-2-yl)carbamoyl)pyridin-2-yl)piperidine-4-carboxylic Acid

  • Catalogue No.:PA 01 2991024

  • CAS :

    NA

  • Molecular Formula : C19H16Cl2N4O3S2

  • Molecular Weight : 483.38

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Drug Reference Standards & Impurity Synthesis in India
PA 01 2991025

1-(1-(5-((4-(4-Chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-yl)carbamoyl)pyridin-2-yl)piperidine-4-carbonyl)piperidine-4-carboxylic Acid

1-(1-(5-((4-(4-Chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-yl)carbamoyl)pyridin-2-yl)piperidine-4-carbonyl)piperidine-4-carboxylic Acid

  • Catalogue No.:PA 01 2991025

  • CAS :

    NA

  • Molecular Formula : C35H44ClN7O4S2

  • Molecular Weight : 726.35

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Drug Reference Standards & Impurity Synthesis in India
PA 01 2991026

1-(3-Chloro-5-((4-(4-chlorothiophen-2-yl)-5-(piperazin-1-yl)thiazol-2-yl)carbamoyl)pyridin-2-yl)piperidine-4-carboxylic Acid

1-(3-Chloro-5-((4-(4-chlorothiophen-2-yl)-5-(piperazin-1-yl)thiazol-2-yl)carbamoyl)pyridin-2-yl)piperidine-4-carboxylic Acid

  • Catalogue No.:PA 01 2991026

  • CAS :

    NA

  • Molecular Formula : C23H24Cl2N6O3S2

  • Molecular Weight : 567.5

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Drug Reference Standards & Impurity Synthesis in India
PA 01 2991027

1-(3-Chloro-5-((4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-yl)carbamoyl)pyridin-2-yl)piperidine-3-carboxylic Acid Maleate

1-(3-Chloro-5-((4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-yl)carbamoyl)pyridin-2-yl)piperidine-3-carboxylic Acid Maleate

  • Catalogue No.:PA 01 2991027

  • CAS :

    NA

  • Molecular Formula : C33H38Cl2N6O7S2

  • Molecular Weight : 765.72

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Drug Reference Standards & Impurity Synthesis in India
PA 01 2991028

4-(4-Chlorothiophen-2-yl)-5-(4-nitrosopiperazin-1-yl)thiazol-2-amine

4-(4-Chlorothiophen-2-yl)-5-(4-nitrosopiperazin-1-yl)thiazol-2-amine

  • Catalogue No.:PA 01 2991028

  • CAS :

    NA

  • Molecular Formula : C11H12ClN5OS2

  • Molecular Weight : 329.82

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Drug Reference Standards & Impurity Synthesis in India
PA 01 2991029

Ethyl 1-(3-chloro-5-((4-(4-chlorothiophen-2-yl)-5-(4-nitrosopiperazin-1-yl)thiazol-2-yl)carbamoyl)pyridin-2-yl)piperidine-4-carboxylate

Ethyl 1-(3-chloro-5-((4-(4-chlorothiophen-2-yl)-5-(4-nitrosopiperazin-1-yl)thiazol-2-yl)carbamoyl)pyridin-2-yl)piperidine-4-carboxylate

  • Catalogue No.:PA 01 2991029

  • CAS :

    NA

  • Molecular Formula : C25H27Cl2N7O4S2

  • Molecular Weight : 624.56

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