Axomadol and its Impurities

Axomadol is a synthetic, centrally-acting opioid analgesic of the benzenoid class which was under investigation by Endo. Pharmaceuticals in collaboration with Grünenthal for the treatment of chronic, moderate to severe lower back pain and arthrosis. Reference standards of Axomadol API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.