benazepril hydrochloride and its Impurities

An ACE inhibitor which is used for the treatment of hypertension, congestive heart failure and heart attacks.Benazepril is a prodrug of its active form, benazeprilat. It is metabolized by the liver where the cleavage of the Benazepril ester group takes place. Reference standards of Benazepril Hydrochloride API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

Displaying 17 results for benazepril hydrochloride Impurities
Drug Reference Standards & Impurity Synthesis in India
PA 02 06000

Benazepril Hydrochloride

Benazepril Hydrochloride


  • Catalogue No.:PA 02 06000

  • CAS :

    86541-74-4

  • Molecular Formula : C24H29ClN2O5

  • Molecular Weight : 460.95

Drug Reference Standards & Impurity Synthesis in India
PA 02 06010

Benazepril Hydrochloride - Impurity A (Freebase)

(3R)-Benazepril


  • Catalogue No.:PA 02 06010

  • CAS :

    131064-75-0

  • Molecular Formula : C24H28N2O5

  • Molecular Weight : 424.49

Drug Reference Standards & Impurity Synthesis in India
PA 02 06011

Benazepril Hydrochloride - Impurity A (HCl Salt)

(3R)-Benazepril Hydrochloride


  • Catalogue No.:PA 02 06011

  • CAS :

    215447-89-5

  • Molecular Formula : C24H29ClN2O5

  • Molecular Weight : 460.95

Drug Reference Standards & Impurity Synthesis in India
PA 02 06020

Benazepril Hydrochloride - Impurity B

[(3RS)-3-[[(1SR)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl]acetic Acid


  • Catalogue No.:PA 02 06020

  • CAS :

    98626-50-7

  • Molecular Formula : C24H28N2O5

  • Molecular Weight : 424.49

Drug Reference Standards & Impurity Synthesis in India
PA 02 06040

Benazepril Hydrochloride - Impurity D (HCl Salt)

(3-(1-Ethoxycarbonyl-3-cyclohexyl-(1S)-propyl)amino-2,3,4,5-tetrahydro-2-oxo-1H-1-(3S)-benzazepine-1-acetic Acid Monohydrochloride


  • Catalogue No.:PA 02 06040

  • CAS :

    2775292-18-5

  • Molecular Formula : C24H35ClN2O5

  • Molecular Weight : 467

Drug Reference Standards & Impurity Synthesis in India
PA 02 06050

Benazepril Hydrochloride - Impurity E (Freebase)

[(3S)-3-Amino-2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl]acetic Acid


  • Catalogue No.:PA 02 06050

  • CAS :

    88372-47-8

  • Molecular Formula : C12H14N2O3

  • Molecular Weight : 234.25

Drug Reference Standards & Impurity Synthesis in India
PA 02 06051

Benazepril Hydrochloride - Impurity E (Hydrochloride Salt)

(S)-3-Amino-2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepine-1-acetic Acid Hydrochloride


  • Catalogue No.:PA 02 06051

  • CAS :

    NA

  • Molecular Formula : C12H15ClN2O3

  • Molecular Weight : 270.71

Drug Reference Standards & Impurity Synthesis in India
PA 02 06060

Benazepril Hydrochloride - Impurity F

1,1-Dimethylethyl [(3S)-3-amino-2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl]Acetate


  • Catalogue No.:PA 02 06060

  • CAS :

    109010-60-8

  • Molecular Formula : C16H22N2O3

  • Molecular Weight : 290.36

Drug Reference Standards & Impurity Synthesis in India
PA 02 06510

Benazepril Hydrochloride - Impurity C

(2S)-2-[[(3S)-1-(Carboxymethyl)-2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-3-yl]amino]-4-phenylbutanoic Acid


  • Catalogue No.:PA 02 06510

  • CAS :

    86541-78-8

  • Molecular Formula : C22H24N2O5

  • Molecular Weight : 396.44

Drug Reference Standards & Impurity Synthesis in India
PA 02 06610

Benazepril Hydrochloride - Impurity G

Ethyl (2S)-2-[[(3S)-1-(2-ethoxy-2-oxoethyl)-2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-3-yl]amino]-4-phenylbutanoate


  • Catalogue No.:PA 02 06610

  • CAS :

    103129-58-4

  • Molecular Formula : C26H32N2O5

  • Molecular Weight : 452.54

Drug Reference Standards & Impurity Synthesis in India
PA 02 0060021

Benazepril Hydrochloride - Impurity B (Hydrochloride Salt)

2-[(SR)-3-{[(RS)-1-Ethoxy-1-oxo-4-phenylbutan-2-yl]amino}-2-oxo-2,3,4,5-tetrahydro-1H -benzo[b]azepin-1-yl]acetic acid Hydrochloride


  • Catalogue No.:PA 02 0060021

  • CAS :

    88372-39-8

  • Molecular Formula : C24H29ClN2O5

  • Molecular Weight : 460.96

Drug Reference Standards & Impurity Synthesis in India
PA 02 0060041

Benazepril Hydrochloride - Impurity D (Freebase)

[(3S)-3-[[(1S)-3-Cyclohexyl-1-(ethoxycarbonyl)propyl]- amino]-2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-1- yl]acetic Acid


  • Catalogue No.:PA 02 0060041

  • CAS :

    112110-48-2

  • Molecular Formula : C24H34N2O5

  • Molecular Weight : 430.55

Drug Reference Standards & Impurity Synthesis in India
PA 02 0061001

7-Bromo Analogue Benazepril Impurity

7-Bromo Analogue Benazepril Impurity


  • Catalogue No.:PA 02 0061001

  • CAS :

    NA

  • Molecular Formula : C24H27BrN2O5

  • Molecular Weight : 503.39

Drug Reference Standards & Impurity Synthesis in India
PA 02 0061002

2-((R)-3-(((S)-1-Ethoxy-1-oxo-4-phenylbutan-2-yl)amino)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-1-yl)acetic Acid Hydrochloride

2-((R)-3-(((S)-1-Ethoxy-1-oxo-4-phenylbutan-2-yl)amino)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-1-yl)acetic Acid Hydrochloride


  • Catalogue No.:PA 02 0061002

  • CAS :

    215447-90-8

  • Molecular Formula : C24H29ClN2O5

  • Molecular Weight : 460.96

Drug Reference Standards & Impurity Synthesis in India
PAI 02 003033

tert-Butyl 2-(3-bromo-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-1-yl)acetate

tert-Butyl 2-(3-bromo-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-1-yl)acetate


  • Catalogue No.:PAI 02 003033

  • CAS :

    1024026-47-8

  • Molecular Formula : C16H20BrNO3

  • Molecular Weight : 354.24

Drug Reference Standards & Impurity Synthesis in India
PAI 02 003034

Ethyl (R)-2-(((R)-1-(2-(tert-butoxy)-2-oxoethyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-3-yl)amino)-4-phenylbutanoate

Ethyl (R)-2-(((R)-1-(2-(tert-butoxy)-2-oxoethyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-3-yl)amino)-4-phenylbutanoate


  • Catalogue No.:PAI 02 003034

  • CAS :

    NA

  • Molecular Formula : C28H36N2O5

  • Molecular Weight : 480.61

Drug Reference Standards & Impurity Synthesis in India
PAI 02 003035

Ethyl (R)-2-(((R)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-3-yl)amino)-4-phenylbutanoate

Ethyl (R)-2-(((R)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-3-yl)amino)-4-phenylbutanoate


  • Catalogue No.:PAI 02 003035

  • CAS :

    NA

  • Molecular Formula : C22H26N2O3

  • Molecular Weight : 366.46

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