bendamustine hydrochloride and its Impurities

An alkylating agent with chemical formula 1Hbenzimidazole-2-butanoic acid, 5-[bis(2-chloroethyl)amino]-1 methyl-, monohydrochloride. It contains a mechlorethamine group and a benzimidazole heterocyclic ring with a butyric acid substituent. It is used for the treatment of chronic lymphocytic leukemia and lymphomas. Reference standards of Bendamustine Hydrochloride API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

Displaying 48 results for bendamustine hydrochloride Impurities
Drug Reference Standards & Impurity Synthesis in India
PA 02 07000

Bendamustine Hydrochloride

Bendamustine Hydrochloride


  • Catalogue No.:PA 02 07000

  • CAS :

    3543-75-7

  • Molecular Formula : C16H22Cl3N3O2

  • Molecular Weight : 394.72

Drug Reference Standards & Impurity Synthesis in India
PA 02 07510

Bendamustine Methyl Ester

Bendamustine Methyl Ester


  • Catalogue No.:PA 02 07510

  • CAS :

    109882-25-9

  • Molecular Formula : C17H23Cl2N3O2

  • Molecular Weight : 372.29

Drug Reference Standards & Impurity Synthesis in India
PA 02 07520

Bendamustine Ethyl Ester

Bendamustine Ethyl Ester


  • Catalogue No.:PA 02 07520

  • CAS :

    87475-54-5

  • Molecular Formula : C18H25Cl2N3O2

  • Molecular Weight : 386.32

Drug Reference Standards & Impurity Synthesis in India
PA 02 07530

Bendamustine Isopropyl Ester

Bendamustine Isopropyl Ester


  • Catalogue No.:PA 02 07530

  • CAS :

    1313020-25-5

  • Molecular Formula : C19H27Cl2N3O2

  • Molecular Weight : 400.34

Drug Reference Standards & Impurity Synthesis in India
PA 02 07540

Dihydroxy Bendamustine

Dihydroxy Bendamustine


  • Catalogue No.:PA 02 07540

  • CAS :

    109882-30-6

  • Molecular Formula : C16H23N3O4

  • Molecular Weight : 321.37

Drug Reference Standards & Impurity Synthesis in India
PA 02 07550

Deschloroethyl Bendamustine Hydrochloride

Deschloroethyl Bendamustine Hydrochloride


  • Catalogue No.:PA 02 07550

  • CAS :

    1797881-48-1

  • Molecular Formula : C14H19Cl2N3O2

  • Molecular Weight : 332.23

Drug Reference Standards & Impurity Synthesis in India
PA 02 07560

Bendamustine Dideschloroethyl Acid

Bendamustine Dideschloroethyl Acid


  • Catalogue No.:PA 02 07560

  • CAS :

    914626-62-3

  • Molecular Formula : C12H15N3O2

  • Molecular Weight : 233.27

Drug Reference Standards & Impurity Synthesis in India
PA 02 07570

Bendamustine Dideschloroethyl Ethyl Ester

Bendamustine Dideschloroethyl Ethyl Ester


  • Catalogue No.:PA 02 07570

  • CAS :

    3543-73-5

  • Molecular Formula : C14H19N3O2

  • Molecular Weight : 261.32

Drug Reference Standards & Impurity Synthesis in India
PA 02 07580

Bendamustine Nitro Ethyl Ester

Bendamustine Nitro Ethyl Ester


  • Catalogue No.:PA 02 07580

  • CAS :

    3543-72-4

  • Molecular Formula : C14H17N3O4

  • Molecular Weight : 291.31

Drug Reference Standards & Impurity Synthesis in India
PA 02 07590

Hydroxy Bendamustine

Hydroxy Bendamustine


  • Catalogue No.:PA 02 07590

  • CAS :

    109882-27-1

  • Molecular Formula : C16H22ClN3O3

  • Molecular Weight : 339.82

Drug Reference Standards & Impurity Synthesis in India
PA 02 07600

5-[(2-Chloroethyl)(2-hydroxyethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic Acid 1-Methylethyl Ester

5-[(2-Chloroethyl)(2-hydroxyethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic Acid 1-Methylethyl Ester


  • Catalogue No.:PA 02 07600

  • CAS :

    1797008-41-3

  • Molecular Formula : C19H28ClN3O3

  • Molecular Weight : 381.9

Drug Reference Standards & Impurity Synthesis in India
PA 02 07610

4-(6-(2-Chloroethyl)-3-methyl-3,6,7,8-tetrahydroimidazo[4',5':5,6]benzo[1,2-b][1,4]thiazin-2-yl)butanoic Acid

4-(6-(2-Chloroethyl)-3-methyl-3,6,7,8-tetrahydroimidazo[4',5':5,6]benzo[1,2-b][1,4]thiazin-2-yl)butanoic Acid


  • Catalogue No.:PA 02 07610

  • CAS :

    191939-34-1

  • Molecular Formula : C16H20ClN3O2S

  • Molecular Weight : 353.87

Drug Reference Standards & Impurity Synthesis in India
PA 02 07620

Isopropyl 4-(1-Methyl-5-nitro-1H-benzo[d]imidazol-2-yl)Butanoate

Isopropyl 4-(1-Methyl-5-nitro-1H-benzo[d]imidazol-2-yl)Butanoate


  • Catalogue No.:PA 02 07620

  • CAS :

    1374784-01-6

  • Molecular Formula : C15H19N3O4

  • Molecular Weight : 305.33

Drug Reference Standards & Impurity Synthesis in India
PA 02 07630

1,3-Bis(1-methyl-5-nitro-1H-benzo[d]imidazol-2-yl)propane

1,3-Bis(1-methyl-5-nitro-1H-benzo[d]imidazol-2-yl)propane


  • Catalogue No.:PA 02 07630

  • CAS :

    914626-65-6

  • Molecular Formula : C19H18N6O4

  • Molecular Weight : 394.38

Drug Reference Standards & Impurity Synthesis in India
PA 02 07640

N1,N5-Bis(2-(methylamino)-5-nitrophenyl)glutaramide

N1,N5-Bis(2-(methylamino)-5-nitrophenyl)glutaramide


  • Catalogue No.:PA 02 07640

  • CAS :

    NA

  • Molecular Formula : C19H22N6O6

  • Molecular Weight : 430.41

Drug Reference Standards & Impurity Synthesis in India
PA 02 07650

2,2'-(Propane-1,3-diyl)bis(1-methyl-1H-benzo[d]imidazol-5-amine)

2,2'-(Propane-1,3-diyl)bis(1-methyl-1H-benzo[d]imidazol-5-amine)


  • Catalogue No.:PA 02 07650

  • CAS :

    847588-86-7

  • Molecular Formula : C19H22N6

  • Molecular Weight : 334.42

Drug Reference Standards & Impurity Synthesis in India
PA 02 07660

2,3-Dihydroxypropyl 4-(5-(bis(2-chloroethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate

2,3-Dihydroxypropyl 4-(5-(bis(2-chloroethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate


  • Catalogue No.:PA 02 07660

  • CAS :

    NA

  • Molecular Formula : C19H27Cl2N3O4

  • Molecular Weight : 432.34

Drug Reference Standards & Impurity Synthesis in India
PA 02 07670

4-(5-((2-Acetoxyethyl)(2-chloroethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoic Acid

4-(5-((2-Acetoxyethyl)(2-chloroethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoic Acid


  • Catalogue No.:PA 02 07670

  • CAS :

    NA

  • Molecular Formula : C18H24ClN3O4

  • Molecular Weight : 381.85

Drug Reference Standards & Impurity Synthesis in India
PA 02 07680

Deschloroethyl Bendamustine

Deschloroethyl Bendamustine


  • Catalogue No.:PA 02 07680

  • CAS :

    1219709-86-0

  • Molecular Formula : C14H18ClN3O2

  • Molecular Weight : 295.76

Drug Reference Standards & Impurity Synthesis in India
PA 02 07690

Methyl 4-(5-(bis(2-hydroxyethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate

Methyl 4-(5-(bis(2-hydroxyethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate


  • Catalogue No.:PA 02 07690

  • CAS :

    109882-31-7

  • Molecular Formula : C17H25N3O4

  • Molecular Weight : 335.4

Drug Reference Standards & Impurity Synthesis in India
PA 02 07700

2-((2-Hydroxyethyl)(2-(4-isopropoxy-4-oxobutyl)-1-methyl-1H-benzo[d]imidazol-5-yl)amino)ethyl 4-(5-(bis(2-hydroxyethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate

2-((2-Hydroxyethyl)(2-(4-isopropoxy-4-oxobutyl)-1-methyl-1H-benzo[d]imidazol-5-yl)amino)ethyl 4-(5-(bis(2-hydroxyethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate


  • Catalogue No.:PA 02 07700

  • CAS :

    NA

  • Molecular Formula : C35H50N6O7

  • Molecular Weight : 666.81

Drug Reference Standards & Impurity Synthesis in India
PA 02 07710

Bendamustine Chloro Dimer Impurity

Bendamustine Chloro Dimer Impurity


  • Catalogue No.:PA 02 07710

  • CAS :

    1228551-91-4

  • Molecular Formula : C32H41Cl3N6O4

  • Molecular Weight : 680.06

Drug Reference Standards & Impurity Synthesis in India
PA 02 07720

4-(5-((2-Hydroxyethyl)(methyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoic Acid

4-(5-((2-Hydroxyethyl)(methyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoic Acid


  • Catalogue No.:PA 02 07720

  • CAS :

    NA

  • Molecular Formula : C15H21N3O3

  • Molecular Weight : 291.35

Drug Reference Standards & Impurity Synthesis in India
PA 02 07730

Isopropyl 4-(5-((2-hydroxyethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate

Isopropyl 4-(5-((2-hydroxyethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate


  • Catalogue No.:PA 02 07730

  • CAS :

    NA

  • Molecular Formula : C17H25N3O3

  • Molecular Weight : 319.4

Drug Reference Standards & Impurity Synthesis in India
PA 02 07740

Bendamustine Deschloro Dimer Impurity

Bendamustine Deschloro Dimer Impurity


  • Catalogue No.:PA 02 07740

  • CAS :

    1391052-61-1

  • Molecular Formula : C32H44N6O7

  • Molecular Weight : 624.73

Drug Reference Standards & Impurity Synthesis in India
PA 02 07750

Bendamustine Dimer 2'-Allyl Ester

Bendamustine Dimer 2'-Allyl Ester


  • Catalogue No.:PA 02 07750

  • CAS :

    NA

  • Molecular Formula : C35H45Cl3N6O4

  • Molecular Weight : 720.13

Drug Reference Standards & Impurity Synthesis in India
PA 02 07770

N-Methyl-2-amino-4-nitroaniline

N-Methyl-2-amino-4-nitroaniline


  • Catalogue No.:PA 02 07770

  • CAS :

    41939-61-1

  • Molecular Formula : C7H9N3O2

  • Molecular Weight : 167.17

Drug Reference Standards & Impurity Synthesis in India
PA 02 07780

4-Chlorobenzene-1,3-diamine

4-Chlorobenzene-1,3-diamine


  • Catalogue No.:PA 02 07780

  • CAS :

    5131-60-2

  • Molecular Formula : C6H7ClN2

  • Molecular Weight : 142.59

Drug Reference Standards & Impurity Synthesis in India
PA 02 07790

N1-Methylbenzene-1,2,4-triamine

N1-Methylbenzene-1,2,4-triamine


  • Catalogue No.:PA 02 07790

  • CAS :

    60651-29-8

  • Molecular Formula : C7H11N3

  • Molecular Weight : 137.19

Drug Reference Standards & Impurity Synthesis in India
PA 02 07800

4-[6-(2-Chloroethyl)-3,6,7,8-tetrahydro-3-methylimidazo[4,5-h][1,4]benzothiazin-2-yl]butanoic Acid Hydrochloride

4-[6-(2-Chloroethyl)-3,6,7,8-tetrahydro-3-methylimidazo[4,5-h][1,4]benzothiazin-2-yl]butanoic Acid Hydrochloride


  • Catalogue No.:PA 02 07800

  • CAS :

    2469039-29-8

  • Molecular Formula : C16H21Cl2N3O2S

  • Molecular Weight : 390.32

Drug Reference Standards & Impurity Synthesis in India
PA 02 07810

Bendamustine Dihydroxy

Bendamustine Dihydroxy


  • Catalogue No.:PA 02 07810

  • CAS :

    109882-29-3

  • Molecular Formula : C16H24ClN3O4

  • Molecular Weight : 357.84

Drug Reference Standards & Impurity Synthesis in India
PA 02 07820

Bendamustine Ether Hydrochloride Impurity

Bendamustine Ether Hydrochloride Impurity


  • Catalogue No.:PA 02 07820

  • CAS :

    2173004-95-8

  • Molecular Formula : C16H22ClN3O3

  • Molecular Weight : 339.82

Drug Reference Standards & Impurity Synthesis in India
PA 02 07840

Bendamustine Mannitol Ester

Bendamustine Mannitol Ester


  • Catalogue No.:PA 02 07840

  • CAS :

    1869075-89-7

  • Molecular Formula : C22H33Cl2N3O7

  • Molecular Weight : 522.42

Drug Reference Standards & Impurity Synthesis in India
PA 02 07850

5-[Bis(2-chloroethyl)amino]-γ-hydroxy-1-methyl-1H-benzimidazole-2-butanoic Acid

5-[Bis(2-chloroethyl)amino]-γ-hydroxy-1-methyl-1H-benzimidazole-2-butanoic Acid


  • Catalogue No.:PA 02 07850

  • CAS :

    1138238-08-0

  • Molecular Formula : C16H21Cl2N3O3

  • Molecular Weight : 374.26

Drug Reference Standards & Impurity Synthesis in India
PA 02 07860

N-Desmethylbendamustine

N-Desmethylbendamustine


  • Catalogue No.:PA 02 07860

  • CAS :

    41515-13-3

  • Molecular Formula : C15H19Cl2N3O2

  • Molecular Weight : 344.24

Drug Reference Standards & Impurity Synthesis in India
PA 02 0071000

Bendamustine Monohydroxy Acid Hydrochloride

Bendamustine Monohydroxy Acid Hydrochloride


  • Catalogue No.:PA 02 0071000

  • CAS :

    109882-26-0

  • Molecular Formula : C16H23Cl2N3O3

  • Molecular Weight : 376.28

Drug Reference Standards & Impurity Synthesis in India
PA 02 0071001

4-(1-Methyl-5-nitro-1H-benzo[d]imidazol-2-yl)butanoic Acid

4-(1-Methyl-5-nitro-1H-benzo[d]imidazol-2-yl)butanoic Acid


  • Catalogue No.:PA 02 0071001

  • CAS :

    31349-48-1

  • Molecular Formula : C12H13N3O4

  • Molecular Weight : 263.25

Drug Reference Standards & Impurity Synthesis in India
PA 02 0071002

N-Methyl-2,4-dinitroaniline

N-Methyl-2,4-dinitroaniline


  • Catalogue No.:PA 02 0071002

  • CAS :

    2044-88-4

  • Molecular Formula : C7H7N3O4

  • Molecular Weight : 197.15

Drug Reference Standards & Impurity Synthesis in India
PA 02 07830

[1-Methyl-5-bis(2'-hydroxyethyl)aminobenzimidazolyl-2]butanoic Acid Ethyl Ester

[1-Methyl-5-bis(2'-hydroxyethyl)aminobenzimidazolyl-2]butanoic Acid Ethyl Ester


  • Catalogue No.:PA 02 07830

  • CAS :

    3543-74-6

  • Molecular Formula : C18H27N3O4

  • Molecular Weight : 349.43

Drug Reference Standards & Impurity Synthesis in India
PA 02 0071003

Bendamustine Ether Impurity

Bendamustine Ether Impurity


  • Catalogue No.:PA 02 0071003

  • CAS :

    1228552-02-0

  • Molecular Formula : C16H21N3O3

  • Molecular Weight : 303.36

Drug Reference Standards & Impurity Synthesis in India
PAI 02 007001

5-((2-Fluoro-5-nitrophenyl)amino)-5-oxopentanoic Acid

5-((2-Fluoro-5-nitrophenyl)amino)-5-oxopentanoic Acid


  • Catalogue No.:PAI 02 007001

  • CAS :

    451459-95-3

  • Molecular Formula : C11H11FN2O5

  • Molecular Weight : 270.22

Drug Reference Standards & Impurity Synthesis in India
PA 02 0071004

Bendamustine Dideschloroethyl Acid Hydrochloride

Bendamustine Dideschloroethyl Acid Hydrochloride


  • Catalogue No.:PA 02 0071004

  • CAS :

    1179363-38-2

  • Molecular Formula : C12H16ClN3O2

  • Molecular Weight : 269.73

Drug Reference Standards & Impurity Synthesis in India
PAI 02 007002

Isopropyl 4-(5-amino-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate

Isopropyl 4-(5-amino-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate


  • Catalogue No.:PAI 02 007002

  • CAS :

    1313020-26-6

  • Molecular Formula : C15H21N3O2

  • Molecular Weight : 275.35

Drug Reference Standards & Impurity Synthesis in India
PAI 02 007003

tert-Butyl 4-(1-methyl-5-nitro-1H-benzo[d]imidazol-2-yl)butanoate

tert-Butyl 4-(1-methyl-5-nitro-1H-benzo[d]imidazol-2-yl)butanoate


  • Catalogue No.:PAI 02 007003

  • CAS :

    NA

  • Molecular Formula : C16H21N3O4

  • Molecular Weight : 319.36

Drug Reference Standards & Impurity Synthesis in India
PAI 02 007004

tert-Butyl 4-(5-amino-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate

tert-Butyl 4-(5-amino-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate


  • Catalogue No.:PAI 02 007004

  • CAS :

    NA

  • Molecular Formula : C16H23N3O2

  • Molecular Weight : 289.38

Drug Reference Standards & Impurity Synthesis in India
PAI 02 007005

tert-Butyl 4-(5-((2-chloroethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate

tert-Butyl 4-(5-((2-chloroethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate


  • Catalogue No.:PAI 02 007005

  • CAS :

    NA

  • Molecular Formula : C18H26ClN3O2

  • Molecular Weight : 351.88

Drug Reference Standards & Impurity Synthesis in India
PA BSC 00702935

[1-Methyl-5-bis(2'-hydroxyethyl)aminobenzimidazolyl-2]butanoic Acid Ethyl Ester (BSC)

[1-Methyl-5-bis(2'-hydroxyethyl)aminobenzimidazolyl-2]butanoic Acid Ethyl Ester


  • Catalogue No.:PA BSC 00702935

  • CAS :

    3543-74-6

  • Molecular Formula : C18H27N3O4

  • Molecular Weight : 349.43

Drug Reference Standards & Impurity Synthesis in India
PA BSC 00702937

Bis(tributyltin) Oxide (BSC)

Bis(tributyltin) Oxide


  • Catalogue No.:PA BSC 00702937

  • CAS :

    56-35-9

  • Molecular Formula : C24H54OSn2

  • Molecular Weight : 596.1

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