bimatoprost and its Impurities
Bimatoprost is used for the treatment of open-angle glaucoma and ocular hypertension in adult patients. It was approved for medical use in the United States in 2001.. Reference standards of Bimatoprost API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below


(E)-7-((1R,2R,3R,5S)-3,5-Dihydroxy-2-((2R)-3-((S)-1-hydroxy-3-phenylpropyl)oxiran-2-yl)cyclopentyl)-N-ethylhept-5-enamide;
(E)-7-((1R,2R,3R,5S)-3,5-Dihydroxy-2-((2R)-3-((S)-1-hydroxy-3-phenylpropyl)oxiran-2-yl)cyclopentyl)-N-ethylhept-5-enamide;
Catalogue No.:PA 02 72550
CAS :
NA
Molecular Formula : C25H37NO5
Molecular Weight : 431.56


Ethyl (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((S,E)-3-hydroxy-5-phenylpent-1-en-1-yl)cyclopentyl)hept-5-enoate
Ethyl (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((S,E)-3-hydroxy-5-phenylpent-1-en-1-yl)cyclopentyl)hept-5-enoate
Catalogue No.:PA 02 72600
CAS :
2925269-65-2
Molecular Formula : C25H36O5
Molecular Weight : 416.56


(3aR,4R,5R,6aS)-4-((S,E)-3-Hydroxy-5-phenylpent-1-enyl)hexahydro-2H-cyclopenta[b]furan-2,5-diol
(3aR,4R,5R,6aS)-4-((S,E)-3-Hydroxy-5-phenylpent-1-enyl)hexahydro-2H-cyclopenta[b]furan-2,5-diol
Catalogue No.:PA 02 0721000
CAS :
856240-62-5
Molecular Formula : C18H24O4
Molecular Weight : 304.39


Isopropyl (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((R,E)-3-hydroxy-5-phenylpent-1-en-1-yl)cyclopentyl)hept-5-enoate
Isopropyl (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((R,E)-3-hydroxy-5-phenylpent-1-en-1-yl)cyclopentyl)hept-5-enoate
Catalogue No.:PA 02 0721003
CAS :
130273-87-9
Molecular Formula : C26H38O5
Molecular Weight : 430.59


(Z)-7-((1R,2R,3R,5R)-3,5-dihydroxy-2-((S,E)-3-hydroxy-5-phenylpent-1-en-1-yl)cyclopentyl)hept-5-enoic acid
(Z)-7-((1R,2R,3R,5R)-3,5-dihydroxy-2-((S,E)-3-hydroxy-5-phenylpent-1-en-1-yl)cyclopentyl)hept-5-enoic acid
Catalogue No.:PA 02 0721004
CAS :
2095712-81-3
Molecular Formula : C23H32O5
Molecular Weight : 388.5


4-(3-(((1R,2R,3R,5S)-3,5-Dihydroxy-2-((S,E)-3-hydroxy-5-phenylpent-1-en-1-yl)cyclopentyl)methyl)oxiran-2-yl)-N-ethylbutanamide
4-(3-(((1R,2R,3R,5S)-3,5-Dihydroxy-2-((S,E)-3-hydroxy-5-phenylpent-1-en-1-yl)cyclopentyl)methyl)oxiran-2-yl)-N-ethylbutanamide
Catalogue No.:PA 02 0721005
CAS :
NA
Molecular Formula : C25H37NO5
Molecular Weight : 431.57