bosentan hydrate and its Impurities

Bosentan Hydrate is used to treat pulmonary hypertension by blocking the action of endothelin molecules that would otherwise promote narrowing of the blood vessels and lead to high blood pressure. It is a dual endothelin receptor antagonist marketed under the trade name Tracleer by Actelion Pharmaceuticals . Reference standards of Bosentan Hydrate API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below

Displaying 23 results for bosentan hydrate Impurities
Drug Reference Standards & Impurity Synthesis in India
PA 02 21000

Bosentan Hydrate

Bosentan Hydrate


  • Catalogue No.:PA 02 21000

  • CAS :

    157212-55-0

  • Molecular Formula : C27H31N5O7S

  • Molecular Weight : 569.63

Drug Reference Standards & Impurity Synthesis in India
PA 02 21510

4-(tert-Butyl)benzenesulfonamide

4-(tert-Butyl)benzenesulfonamide


  • Catalogue No.:PA 02 21510

  • CAS :

    6292-59-7

  • Molecular Formula : C10H15NO2S

  • Molecular Weight : 213.3

Drug Reference Standards & Impurity Synthesis in India
PA 02 21520

4-(tert-Butyl)benzene-1-sulfonyl chloride

4-(tert-Butyl)benzene-1-sulfonyl chloride


  • Catalogue No.:PA 02 21520

  • CAS :

    15084-51-2

  • Molecular Formula : C10H13ClO2S

  • Molecular Weight : 232.73

Drug Reference Standards & Impurity Synthesis in India
PA 02 21530

4-(tert-Butyl)-N-[6-chloro-5-(2-methoxyphenoxy)-(2,2'-bipyrimidin)-4-yl] benzenesulfonamide

4-(tert-Butyl)-N-[6-chloro-5-(2-methoxyphenoxy)-(2,2'-bipyrimidin)-4-yl] benzenesulfonamide


  • Catalogue No.:PA 02 21530

  • CAS :

    150727-06-3

  • Molecular Formula : C25H24ClN5O4S

  • Molecular Weight : 526.01

Drug Reference Standards & Impurity Synthesis in India
PA 02 21540

4-(tert-Butyl)-N-[6-hydroxy-5-(2-methoxyphenoxy)-(2,2'-bipyrimidin)-4-yl]benzenesulfonamide

4-(tert-Butyl)-N-[6-hydroxy-5-(2-methoxyphenoxy)-(2,2'-bipyrimidin)-4-yl]benzenesulfonamide


  • Catalogue No.:PA 02 21540

  • CAS :

    174227-14-6

  • Molecular Formula : C25H25N5O5S

  • Molecular Weight : 507.56

Drug Reference Standards & Impurity Synthesis in India
PA 02 21550

6-Chloro-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4(3H)-one

6-Chloro-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4(3H)-one


  • Catalogue No.:PA 02 21550

  • CAS :

    1268612-27-6

  • Molecular Formula : C15H11ClN4O3

  • Molecular Weight : 330.73

Drug Reference Standards & Impurity Synthesis in India
PA 02 21560

Hydroxy Bosentan

Hydroxy Bosentan


  • Catalogue No.:PA 02 21560

  • CAS :

    253688-60-7

  • Molecular Formula : C27H29N5O7S

  • Molecular Weight : 567.61

Drug Reference Standards & Impurity Synthesis in India
PA 02 21570

4,6-Dichloro-5-(2-methoxyphenoxy)-2,2'-bipyrimidine

4,6-Dichloro-5-(2-methoxyphenoxy)-2,2'-bipyrimidine


  • Catalogue No.:PA 02 21570

  • CAS :

    150728-13-5

  • Molecular Formula : C15H10Cl2N4O2

  • Molecular Weight : 349.17

Drug Reference Standards & Impurity Synthesis in India
PA 02 21580

4-(tert-Butyl)-N,N-bis(6-chloro-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)benzenesulfonamide

4-(tert-Butyl)-N,N-bis(6-chloro-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)benzenesulfonamide


  • Catalogue No.:PA 02 21580

  • CAS :

    NA

  • Molecular Formula : C40H33Cl2N9O6S

  • Molecular Weight : 838.72

Drug Reference Standards & Impurity Synthesis in India
PA 02 21590

N,N'-[5-(2-Methoxyphenoxy)[2,2'-bipyrimidine]-4,6-diyl]bis[4-(1,1-dimethylethyl)benzenesulfonamide]

N,N'-[5-(2-Methoxyphenoxy)[2,2'-bipyrimidine]-4,6-diyl]bis[4-(1,1-dimethylethyl)benzenesulfonamide]


  • Catalogue No.:PA 02 21590

  • CAS :

    1218951-81-5

  • Molecular Formula : C35H38N6O6S2

  • Molecular Weight : 702.84

Drug Reference Standards & Impurity Synthesis in India
PA 02 21600

4-(tert-Butyl)-N-(6-methoxy-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)benzenesulfonamide

4-(tert-Butyl)-N-(6-methoxy-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)benzenesulfonamide


  • Catalogue No.:PA 02 21600

  • CAS :

    NA

  • Molecular Formula : C26H27N5O5S

  • Molecular Weight : 521.59

Drug Reference Standards & Impurity Synthesis in India
PA 02 21610

N-(6-(2-Hydroxyethoxy)-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)-4-isopropylbenzenesulfonamide

N-(6-(2-Hydroxyethoxy)-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)-4-isopropylbenzenesulfonamide


  • Catalogue No.:PA 02 21610

  • CAS :

    1268612-24-3

  • Molecular Formula : C26H27N5O6S

  • Molecular Weight : 537.59

Drug Reference Standards & Impurity Synthesis in India
PA 02 21620

Bosentan Dimer Impurity

Bosentan Dimer Impurity


  • Catalogue No.:PA 02 21620

  • CAS :

    1097263-60-9

  • Molecular Formula : C52H52N10O10S2

  • Molecular Weight : 1041.16

Drug Reference Standards & Impurity Synthesis in India
PA 02 21630

2-tert-Butylbenzenesulfonamide

2-tert-Butylbenzenesulfonamide


  • Catalogue No.:PA 02 21630

  • CAS :

    193013-72-8

  • Molecular Formula : C10H15NO2S

  • Molecular Weight : 213.3

Drug Reference Standards & Impurity Synthesis in India
PA 02 0211000

4-(tert-Butyl)-N-((4-(tert-Butyl)phenyl)sulfonyl)benzenesulfonamide

4-(tert-Butyl)-N-((4-(tert-Butyl)phenyl)sulfonyl)benzenesulfonamide


  • Catalogue No.:PA 02 0211000

  • CAS :

    1355251-10-3

  • Molecular Formula : C20H27NO4S2

  • Molecular Weight : 409.56

Drug Reference Standards & Impurity Synthesis in India
PA 02 0211001

4-(tert-Butyl)-N-(5-(2-methoxyphenoxy)-6-(vinyloxy)-[2,2'-bipyrimidin]-4-yl)benzenesulfonamide

4-(tert-Butyl)-N-(5-(2-methoxyphenoxy)-6-(vinyloxy)-[2,2'-bipyrimidin]-4-yl)benzenesulfonamide


  • Catalogue No.:PA 02 0211001

  • CAS :

    1257099-44-7

  • Molecular Formula : C27H27N5O5S

  • Molecular Weight : 533.6

Drug Reference Standards & Impurity Synthesis in India
PA 02 0211002

4-(tert-Butyl)-N-(6-ethoxy-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)benzenesulfonamide

4-(tert-Butyl)-N-(6-ethoxy-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)benzenesulfonamide


  • Catalogue No.:PA 02 0211002

  • CAS :

    157415-45-7

  • Molecular Formula : C27H29N5O5S

  • Molecular Weight : 535.62

Drug Reference Standards & Impurity Synthesis in India
PA 02 0211003

Desmethyl Bosentan

Desmethyl Bosentan


  • Catalogue No.:PA 02 0211003

  • CAS :

    253688-61-8

  • Molecular Formula : C26H27N5O6S

  • Molecular Weight : 537.59

Drug Reference Standards & Impurity Synthesis in India
PA 02 0211004

Hydroxy O-Desmethyl Bosentan

Hydroxy O-Desmethyl Bosentan


  • Catalogue No.:PA 02 0211004

  • CAS :

    253688-62-9

  • Molecular Formula : C26H27N5O7S

  • Molecular Weight : 553.59

Drug Reference Standards & Impurity Synthesis in India
PA 02 0211005

2-((6-((4-(tert-Butyl)phenyl)sulfonamido)-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)oxy)ethyl Acetate

2-((6-((4-(tert-Butyl)phenyl)sulfonamido)-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)oxy)ethyl Acetate


  • Catalogue No.:PA 02 0211005

  • CAS :

    1160515-53-6

  • Molecular Formula : C29H31N5O7S

  • Molecular Weight : 593.66

Drug Reference Standards & Impurity Synthesis in India
PA 02 0211006

4-(tert-Butyl)-N-(6-(2-(2-hydroxyethoxy)ethoxy)-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)benzenesulfonamide

4-(tert-Butyl)-N-(6-(2-(2-hydroxyethoxy)ethoxy)-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)benzenesulfonamide


  • Catalogue No.:PA 02 0211006

  • CAS :

    1257099-43-6

  • Molecular Formula : C29H33N5O7S

  • Molecular Weight : 595.67

Drug Reference Standards & Impurity Synthesis in India
PA 02 0211008

Cesium ((4-(tert-butyl)phenyl)sulfonyl)(6-chloro-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)amide

Cesium ((4-(tert-butyl)phenyl)sulfonyl)(6-chloro-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)amide


  • Catalogue No.:PA 02 0211008

  • CAS :

    1218951-79-1

  • Molecular Formula : C25H23ClCsN5O4S

  • Molecular Weight : 657.91

Drug Reference Standards & Impurity Synthesis in India
PAI 02 021001

N-(6-Amino-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)-4-(tert-butyl)benzenesulfonamide

N-(6-Amino-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)-4-(tert-butyl)benzenesulfonamide


  • Catalogue No.:PAI 02 021001

  • CAS :

    NA

  • Molecular Formula : C25H26N6O4S

  • Molecular Weight : 506.58

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