bromisoval and its Impurities
Bromovisal can be prepared by bromination of isovaleric acid by the Hell-Volhard-Zelinsky reaction followed by reaction with urea. It commonly known as bromovalerylurea, is a hypnotic and sedative of the bromoureide group.. Reference standards of Bromisoval API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below