budesonide and its Impurities
Budesonide is nebulized for maintenance and prophylactic treatment of asthma including patients who require oral corticosteroids and those who may benefit from a systemic dose reduction. It was initially patented in 1973. It sold under the brand name Pulmicort among others, is a medication of the corticosteroid type.. Reference standards of Budesonide API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below
2-((6aR,6bS,7S,8aS,8bS,11aR,12aS,12bS)-7-Hydroxy-6a,8a-dimethyl-4-oxo-10-propyl-2,4,6a,6b,7,8,8a,8b,11a,12,12a,12b-dodecahydro-1H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-8b-yl)-2-oxoacetic Acid
2-((6aR,6bS,7S,8aS,8bS,11aR,12aS,12bS)-7-Hydroxy-6a,8a-dimethyl-4-oxo-10-propyl-2,4,6a,6b,7,8,8a,8b,11a,12,12a,12b-dodecahydro-1H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-8b-yl)-2-oxoacetic Acid
Catalogue No.:PA 02 54720
CAS :
NA
Molecular Formula : C25H32O7
Molecular Weight : 444.52
Budesonide Related Compound E (16alpha,17-[butylidenebis(oxy)]-11Beta,21-dihydroxypregna-1,4,14-tri (1078245)
Budesonide Related Compound E (16alpha,17-[butylidenebis(oxy)]-11Beta,21-dihydroxypregna-1,4,14-tri (1078245)
Catalogue No.:PA USP1078245
CAS :
131918-64-4
Molecular Formula : NA
Molecular Weight : NA
Budesonide Related Compound G (16alpha,17-[butylidenebis(oxy)]-11beta, 21-dihydroxypregna-4-ene-3,2 (1078267)
Budesonide Related Compound G (16alpha,17-[butylidenebis(oxy)]-11beta, 21-dihydroxypregna-4-ene-3,2 (1078267)
Catalogue No.:PA USP1078267
CAS :
137174-25-5
Molecular Formula : NA
Molecular Weight : NA
Budesonide Related Compound L (16alpha,17-[butylidenebis(oxy)]-21-hydroxypregna-1,4-diene-3,11,20-t (1078289)
Budesonide Related Compound L (16alpha,17-[butylidenebis(oxy)]-21-hydroxypregna-1,4-diene-3,11,20-t (1078289)
Catalogue No.:PA USP1078289
CAS :
216453-74-6
Molecular Formula : NA
Molecular Weight : NA
2-((8aS,8bS,11aR)-6a,8a-Dimethyl-4-oxo-10-propyl-2,4,6a,8,8a,8b,11a,12,12a,12b-decahydro-1H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-8b-yl)-2-oxoethyl Acetate
2-((8aS,8bS,11aR)-6a,8a-Dimethyl-4-oxo-10-propyl-2,4,6a,8,8a,8b,11a,12,12a,12b-decahydro-1H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-8b-yl)-2-oxoethyl Acetate
Catalogue No.:PAI 02 008010
CAS :
NA
Molecular Formula : C27H34O6
Molecular Weight : 454.56
(8aS,8bS,11aR)-8b-(2-Acetoxyacetyl)-6a,8a-dimethyl-4-oxo-10-propyl-1,2,4,6a,7a,8,8a,8b,11a,12,12a,12b-dodecahydro-[1,3]dioxolo[4'',5'':3',4']cyclopenta[1',2':1,2]phenanthro[4,4a-b]bromiren-7-ium
(8aS,8bS,11aR)-8b-(2-Acetoxyacetyl)-6a,8a-dimethyl-4-oxo-10-propyl-1,2,4,6a,7a,8,8a,8b,11a,12,12a,12b-dodecahydro-[1,3]dioxolo[4'',5'':3',4']cyclopenta[1',2':1,2]phenanthro[4,4a-b]bromiren-7-ium
Catalogue No.:PAI 02 008020
CAS :
NA
Molecular Formula : C27H34BrO6+
Molecular Weight : 534.46
2-((8aS,8bS,11aR)-6a,8a-Dimethyl-4-oxo-10-propyl-1,2,4,6a,7a,8,8a,8b,11a,12,12a,12b-dodecahydronaphtho[2',1':4,5]oxireno[2',3':5,6]indeno[1,2-d][1,3]dioxol-8b-yl)-2-oxoethyl Acetate
2-((8aS,8bS,11aR)-6a,8a-Dimethyl-4-oxo-10-propyl-1,2,4,6a,7a,8,8a,8b,11a,12,12a,12b-dodecahydronaphtho[2',1':4,5]oxireno[2',3':5,6]indeno[1,2-d][1,3]dioxol-8b-yl)-2-oxoethyl Acetate
Catalogue No.:PAI 02 008030
CAS :
NA
Molecular Formula : C27H34O7
Molecular Weight : 470.55
2-((6aR,6bS,8aS,8bS,11aR,12aS,12bS)-6a,8a-Dimethyl-4,7-dioxo-10-propyl-2,4,6a,6b,7,8,8a,8b,11a,12,12a,12b-dodecahydro-1H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-8b-yl)-2-oxoethyl Acetate
2-((6aR,6bS,8aS,8bS,11aR,12aS,12bS)-6a,8a-Dimethyl-4,7-dioxo-10-propyl-2,4,6a,6b,7,8,8a,8b,11a,12,12a,12b-dodecahydro-1H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-8b-yl)-2-oxoethyl Acetate
Catalogue No.:PAI 02 008040
CAS :
NA
Molecular Formula : C27H34O7
Molecular Weight : 470.55
(7S,8aS,8bS,11aR)-8b-(2-((Tert-butyldimethylsilyl)oxy)acetyl)-7-hydroxy-6a,8a-dimethyl-10-propyl-1,2,6a,6b,7,8,8a,8b,11a,12,12a,12b-dodecahydro-4H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-4-one
(7S,8aS,8bS,11aR)-8b-(2-((Tert-butyldimethylsilyl)oxy)acetyl)-7-hydroxy-6a,8a-dimethyl-10-propyl-1,2,6a,6b,7,8,8a,8b,11a,12,12a,12b-dodecahydro-4H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-4-one
Catalogue No.:PAI 02 008050
CAS :
NA
Molecular Formula : C31H48O6Si
Molecular Weight : 544.80
(6aR,6bS,7S,8aS,8bS,11aR,12aS,12bS)-7,10-Dihydroxy-6a,8a-dimethyl-1,2,6a,6b,7,8,8a,8b,11a,12,12a,12b-dodecahydro-4H-naphtho[2',1':4,5]indeno[2,1-b]furan-4,9(10H)-dione
(6aR,6bS,7S,8aS,8bS,11aR,12aS,12bS)-7,10-Dihydroxy-6a,8a-dimethyl-1,2,6a,6b,7,8,8a,8b,11a,12,12a,12b-dodecahydro-4H-naphtho[2',1':4,5]indeno[2,1-b]furan-4,9(10H)-dione
Catalogue No.:PA 02 54770
CAS :
77017-17-5
Molecular Formula : C21H26O5
Molecular Weight : 358.43
2-((8S,9S,10R,11S,13S,14S,17S)-11,17-Dihydroxy-10,13-dimethyl-3,16-dioxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl Acetate
2-((8S,9S,10R,11S,13S,14S,17S)-11,17-Dihydroxy-10,13-dimethyl-3,16-dioxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl Acetate
Catalogue No.:PAI 02 008070
CAS :
115098-35-6
Molecular Formula : C23H28O7
Molecular Weight : 416.47
2-((8R,9S,10R,11S,13S,17S)-11,17-Dihydroxy-10,13-dimethyl-3,16-dioxo-6,7,8,9,10,11,12,13,16,17-decahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl Acetate
2-((8R,9S,10R,11S,13S,17S)-11,17-Dihydroxy-10,13-dimethyl-3,16-dioxo-6,7,8,9,10,11,12,13,16,17-decahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl Acetate
Catalogue No.:PAI 02 008080
CAS :
NA
Molecular Formula : C23H26O7
Molecular Weight : 414.45
2-((6aR,6bS,7S,8aS,8bS,11aR,12bR)-7-Hydroxy-6a,8a-dimethyl-4-oxo-10-propyl-1,2,4,6a,6b,7,8,8a,11a,12b-decahydro-8bH-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-8b-yl)-2-oxoethyl Acetate
2-((6aR,6bS,7S,8aS,8bS,11aR,12bR)-7-Hydroxy-6a,8a-dimethyl-4-oxo-10-propyl-1,2,4,6a,6b,7,8,8a,11a,12b-decahydro-8bH-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-8b-yl)-2-oxoethyl Acetate
Catalogue No.:PAI 02 008100
CAS :
2408395-13-9
Molecular Formula : C27H34O7
Molecular Weight : 470.56
(8S,9S,10R,11S,13S,14S)-17-(2,2-Dihydroxyacetyl)-11-hydroxy-10,13-dimethyl-6,7,8,9,10,11,12,13,14,15-decahydro-3H-cyclopenta[a]phenanthren-3-one
(8S,9S,10R,11S,13S,14S)-17-(2,2-Dihydroxyacetyl)-11-hydroxy-10,13-dimethyl-6,7,8,9,10,11,12,13,14,15-decahydro-3H-cyclopenta[a]phenanthren-3-one
Catalogue No.:PA 02 54790
CAS :
NA
Molecular Formula : C21H26O5
Molecular Weight : 358.43
(8R,9S,10R,11S,13S,16R,17S)-11,16,17-Trihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,10,11,12,13,16,17-decahydro-3H-cyclopenta[a]phenanthren-3-one
(8R,9S,10R,11S,13S,16R,17S)-11,16,17-Trihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,10,11,12,13,16,17-decahydro-3H-cyclopenta[a]phenanthren-3-one
Catalogue No.:PA 02 0541007
CAS :
131918-73-5
Molecular Formula : C21H26O6
Molecular Weight : 374.43
(8S,9R,10S,11S,13S,14S,16R,17S)-9-Bromo-11,16,17-trihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one
(8S,9R,10S,11S,13S,14S,16R,17S)-9-Bromo-11,16,17-trihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one
Catalogue No.:PA 02 0541008
CAS :
2451559-88-7
Molecular Formula : C21H27BrO6
Molecular Weight : 455.35
2-((8S,9S,10R,13S,14S,16R,17S)-16,17-Dihydroxy-10,13-dimethyl-3,11-dioxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl acetate
2-((8S,9S,10R,13S,14S,16R,17S)-16,17-Dihydroxy-10,13-dimethyl-3,11-dioxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl acetate
Catalogue No.:PA 02 0541009
CAS :
3949-79-9
Molecular Formula : C23H28O7
Molecular Weight : 416.47
2-((8S,10S,13S,14S,16R,17S)-16,17-Dihydroxy-10,13-dimethyl-3-oxo-6,7,8,10,12,13,14,15,16,17-decahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl acetate
2-((8S,10S,13S,14S,16R,17S)-16,17-Dihydroxy-10,13-dimethyl-3-oxo-6,7,8,10,12,13,14,15,16,17-decahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl acetate
Catalogue No.:PA 02 0541010
CAS :
77017-20-0
Molecular Formula : C23H28O6
Molecular Weight : 400.47
2-((8S,10S,13S,14S,16R,17S)-16-Acetoxy-17-hydroxy-10,13-dimethyl-3-oxo-6,7,8,10,12,13,14,15,16,17-decahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl acetate
2-((8S,10S,13S,14S,16R,17S)-16-Acetoxy-17-hydroxy-10,13-dimethyl-3-oxo-6,7,8,10,12,13,14,15,16,17-decahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl acetate
Catalogue No.:PA 02 0541011
CAS :
95943-95-6
Molecular Formula : C25H30O7
Molecular Weight : 442.51
2-((6aR,6bS,7S,8aS,8bS,11aR,12aS,12bS)-7-Hydroxy-6a,8a-dimethyl-4-oxo-10-propyl-1,2,4,6a,6b,7,8,8a,11a,12,12a,12b-dodecahydro-8bH-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-8b-yl)-2-oxoacetic acid
2-((6aR,6bS,7S,8aS,8bS,11aR,12aS,12bS)-7-Hydroxy-6a,8a-dimethyl-4-oxo-10-propyl-1,2,4,6a,6b,7,8,8a,11a,12,12a,12b-dodecahydro-8bH-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-8b-yl)-2-oxoacetic acid
Catalogue No.:PA 02 0541012
CAS :
NA
Molecular Formula : C25H32O7
Molecular Weight : 444.52
2-((8S,9S,10R,11S,13S,14S)-11-Hydroxy-10,13-dimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15-decahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoacetaldehyde
2-((8S,9S,10R,11S,13S,14S)-11-Hydroxy-10,13-dimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15-decahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoacetaldehyde
Catalogue No.:PA 02 0541016
CAS :
NA
Molecular Formula : C21H24O4
Molecular Weight : 340.42
(8S,9R,10S,11S,13S,14S,16R,17S)-9-Bromo-11,16,17-trihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one
(8S,9R,10S,11S,13S,14S,16R,17S)-9-Bromo-11,16,17-trihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one
Catalogue No.:PA 02 0541019
CAS :
3051849-31-8
Molecular Formula : C21H27BrO6
Molecular Weight : 455.35
(2R,11S)-2,3,11-Trihydroxy-2-(hydroxymethyl)-10a,12a-dimethyl-3,4,4a,5,6,10a,10b,11,12,12a-decahydrochrysene-1,8(2H,4bH)-dione
(2R,11S)-2,3,11-Trihydroxy-2-(hydroxymethyl)-10a,12a-dimethyl-3,4,4a,5,6,10a,10b,11,12,12a-decahydrochrysene-1,8(2H,4bH)-dione
Catalogue No.:PAI 02 008101
CAS :
NA
Molecular Formula : C21H28O6
Molecular Weight : 376.45
2-((8S,9S,10R,11S,13S,14S)-11-Hydroxy-10,13-dimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15-decahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoacetaldehyde with (8S,9S,10R,11S,13S,14S)-17-(2,2-dihydroxyacetyl)-11-hydroxy-10,13-dimethyl-6,7,8,9,10,11,12,13,14,15-decahydro-3H-cyclopenta[a]phenanthren-3-one
2-((8S,9S,10R,11S,13S,14S)-11-Hydroxy-10,13-dimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15-decahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoacetaldehyde with (8S,9S,10R,11S,13S,14S)-17-(2,2-dihydroxyacetyl)-11-hydroxy-10,13-dimethyl-6,7,8,9,10,11,12,13,14,15-decahydro-3H-cyclopenta[a]phenanthren-3-one
Catalogue No.:PA 02 0541022
CAS :
NA
Molecular Formula : NA
Molecular Weight : NA
(4aR,4bS,5S,6aS,7aR,9R,10aR,11aS,11bS)-5-Hydroxy-7a-(hydroxymethyl)-4a,6a-dimethyl-9-propyl-4b,6,6a,7a,10a,11,11a,11b,12,13-decahydrochryseno[2,3-d][1,3]dioxole-2,7(4aH,5H)-dione
(4aR,4bS,5S,6aS,7aR,9R,10aR,11aS,11bS)-5-Hydroxy-7a-(hydroxymethyl)-4a,6a-dimethyl-9-propyl-4b,6,6a,7a,10a,11,11a,11b,12,13-decahydrochryseno[2,3-d][1,3]dioxole-2,7(4aH,5H)-dione
Catalogue No.:PA 02 0541023
CAS :
2409483-24-3
Molecular Formula : C25H34O6
Molecular Weight : 430.54
(6aR,6bS,7S,8aS,8bS,10R,11aR,12bR)-7-Hydroxy-8b-(2-hydroxyacetyl)-6a,8a-dimethyl-10-propyl-1,2,6a,6b,7,8,8a,8b,11a,12b-decahydro-4H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-4-one
(6aR,6bS,7S,8aS,8bS,10R,11aR,12bR)-7-Hydroxy-8b-(2-hydroxyacetyl)-6a,8a-dimethyl-10-propyl-1,2,6a,6b,7,8,8a,8b,11a,12b-decahydro-4H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-4-one
Catalogue No.:PA 02 0541024
CAS :
2409483-26-5
Molecular Formula : C25H32O6
Molecular Weight : 428.53
(6aR,6bS,8aS,8bS,10R,11aR,12aS,12bS)-8b-(2-Hydroxyacetyl)-6a,8a-dimethyl-10-propyl-1,6a,6b,8,8a,8b,11a,12,12a,12b-decahydro-4H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxole-4,7(2H)-dione
(6aR,6bS,8aS,8bS,10R,11aR,12aS,12bS)-8b-(2-Hydroxyacetyl)-6a,8a-dimethyl-10-propyl-1,6a,6b,8,8a,8b,11a,12,12a,12b-decahydro-4H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxole-4,7(2H)-dione
Catalogue No.:PA 02 0541025
CAS :
887130-65-6
Molecular Formula : C25H32O6
Molecular Weight : 428.53
(6aR,6bS,7S,8aS,8bS,10R,11aR,12aS,12bS)-7-Hydroxy-8b-(2-hydroxyacetyl)-6a,8a-dimethyl-10-propyl-1,2,5,6,6a,6b,7,8,8a,8b,11a,12,12a,12b-tetradecahydro-4H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-4-one
(6aR,6bS,7S,8aS,8bS,10R,11aR,12aS,12bS)-7-Hydroxy-8b-(2-hydroxyacetyl)-6a,8a-dimethyl-10-propyl-1,2,5,6,6a,6b,7,8,8a,8b,11a,12,12a,12b-tetradecahydro-4H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-4-one
Catalogue No.:PA 02 0541026
CAS :
83649-24-5
Molecular Formula : C25H36O6
Molecular Weight : 432.56
(10R,11S,13S)-11-Hydroxy-10,13-dimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15-decahydro-3H-cyclopenta[a]phenanthrene-17-carboxylic Acid
(10R,11S,13S)-11-Hydroxy-10,13-dimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15-decahydro-3H-cyclopenta[a]phenanthrene-17-carboxylic Acid
Catalogue No.:PA 02 0541027
CAS :
NA
Molecular Formula : C20H24O4
Molecular Weight : 328.41
