Cabazitaxel Acetone and its Impurities

Cabazitaxel, sold under the brand name Jevtana, is a semi-synthetic derivative of a natural taxoid. It is a microtubule inhibitor, and the fourth taxane to be approved as a cancer therapy. Reference standards of Cabazitaxel Acetone API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.