Cabazitaxel was developed by Sanofi-Aventis and was approved by the U.S. FDA for the treatment of hormone-refractory prostate cancer on June 17, 2010. It is a semi-synthetic derivative of a natural taxoid. It is a microtubule inhibitor, and the fourth taxane to be approved as a cancer therapy.. Reference standards of Cabazitaxel API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below
Cabazitaxel
Catalogue No.:PA 03 01000
CAS :
Molecular Formula : C45H57NO14
Molecular Weight : 835.93
De-boc Cabazitaxel
Catalogue No.:PA 03 01510
Molecular Formula : C40H49NO12
Molecular Weight : 735.82
10-Deacetyl-7,10-dimethoxy-Baccatin III
Catalogue No.:PA 03 01520
Molecular Formula : C31H40O10
Molecular Weight : 572.64
Cabazitaxel N-formyl Impurity
Catalogue No.:PA 03 01530
Molecular Formula : C41H49NO13
Molecular Weight : 763.83
10-Deacetyl-7,10,13-trimethyl Baccatin III
Catalogue No.:PA 03 01540
Molecular Formula : C32H42O10
Molecular Weight : 586.67
(2'S,3'R)-Cabazitaxel
Catalogue No.:PA 03 01550
Cabazitaxel Di Boc Impurity
Catalogue No.:PA 03 01560
Molecular Formula : C50H67NO16
Molecular Weight : 938.06
Oxazolidine Cabazitaxel
Catalogue No.:PA 03 01570
Molecular Formula : C48H61NO14
Molecular Weight : 876
2-Debenzoyl-2-tigloyl 10-Deacetyl Baccatin III
Catalogue No.:PA 03 01580
Molecular Formula : C27H38O10
Molecular Weight : 522.58
(4S,5S)-3-(tert-Butoxycarbonyl)-2-(4-methoxyphenyl)-4-phenyloxazolidine-5-carboxylic Acid
Catalogue No.:PA 03 01590
Molecular Formula : C22H25NO6
Molecular Weight : 399.44
(4R,5R)-3-(tert-Butoxycarbonyl)-2-(4-methoxyphenyl)-4-phenyloxazolidine-5-carboxylic Acid
Catalogue No.:PA 03 01600
(4R,5S)-2,2-Dimethyl-4-phenyl-3,5-oxazolidinedicarboxylic Acid 3-(1,1-Dimethylethyl) Ester
Catalogue No.:PA 03 01610
Molecular Formula : C17H23NO5
Molecular Weight : 321.37
(4R,5R)-3-(tert-Butoxycarbonyl)-2,2-dimethyl-4-phenyloxazolidine-5-carboxylic Acid
Catalogue No.:PA 03 01620
(4S,5S)-2,2-Dimethyl-4-phenyl-3,5-oxazolidinedicarboxylic Acid 3-(1,1-Dimethylethyl) Ester
Catalogue No.:PA 03 01630
Cabazitaxel-d6
Catalogue No.:PA STI 016870
Molecular Formula : C45H51D6NO14
Molecular Weight : 841.97
(2'S, 3'R)-Cabazitaxel-D6
Catalogue No.:PA STI 016880
4-Deacetyl-4-propionyl Cabazitaxel-D6
Catalogue No.:PA STI 024550
Molecular Formula : C46H53D6NO14
Molecular Weight : 856.00
10-Methyl Docetaxel
Catalogue No.:PA 03 01640
Molecular Formula : C44H55NO14
Molecular Weight : 821.92
10-Methoxy-10-deacetylbaccatin III
Catalogue No.:PA 03 01650
Molecular Formula : C30H38O10
Molecular Weight : 558.62
10-Deacetyl-7-methyl Baccatin III
Catalogue No.:PA 03 01660
4,10-Desdiacetyl-7,10-dimethyl-4-propionyl Baccatin III
Catalogue No.:PA 03 01670
Molecular Weight : 586.68
Cabazitaxel N-1
Catalogue No.:PA 03 01680
Molecular Formula : C53H63NO15
Molecular Weight : 954.08
13α-[[(2R,3S)-3-[(Tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoyl]oxy]-1-hydroxy7β,10β-dimethoxy-9-oxo-4-(propanoyloxy)-4α,5β-5,20-epoxytax-11-en-2α-yl Benzoate
Catalogue No.:PA 03 01690
Molecular Formula : C46H59NO14
Molecular Weight : 849.97
4-(Acetyloxy)-10β,13α-bis[[(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3- phenylpropanoyl]oxy]-1-hydroxy-7β-methoxy-9-oxo-4α,5β-5,20-epoxytax-11-en-2α-yl Benzoate
Catalogue No.:PA 04 97670
Molecular Formula : C58H72N2O18
Molecular Weight : 1085.21
(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-Acetoxy-9-(((2R,3S)-3-((tert-butoxycarbonyl)amino)-3-phenyl-2-((triethylsilyl)oxy)propanoyl)oxy)-11-hydroxy-4,6-dimethoxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxet-12-yl Benzoate
Catalogue No.:PA 03 01700
Molecular Formula : C51H71NO14Si
Molecular Weight : 950.21
4-(Acetyloxy)-13α-[[(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoyl]oxy]-1-hydroxy-7β,10β-dimethoxy-9-oxo-4α,5β-5,20-epoxytax-11-en-2α-yl (2E)-2-methylbut-2-enoate
Catalogue No.:PA 03 01710
Molecular Formula : C43H59NO14
Molecular Weight : 813.94
(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-Acetoxy-9-(((2R,3S)-3-((tert-butoxycarbonyl)amino)-2-hydroxy-3-phenylpropanoyl)oxy)-11-hydroxy-4,6-dimethoxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxet-12-yl Benzoate compound with Propan-2-ol (1:1)
Catalogue No.:PA 03 01720
Molecular Formula : C48H65NO15
Molecular Weight : 896.04
Cabazitaxel-d9
Catalogue No.:PA STI 016881
Molecular Formula : C45H48D9NO14
Molecular Weight : 845.00
N',O'-(4-Methoxybenzylidene)cabazitaxel
Catalogue No.:PA 03 0011000
(2aR,4S,4aS,6R,8S,9aS,10S,10aR,10bS)-10b-Acetoxy-8-(((2R,3S)-3-((tert-butoxycarbonyl)amino)-2-hydroxy-3-phenylpropanoyl)oxy)-9a-(2-hydroxypropan-2-yl)-4,6-dimethoxy-4a,7-dimethyl-5-oxo-2a,3,4,4a,5,6,8,9,9a,10,10a,10b-dodecahydro-1H-azuleno[5',6':3,4]benzo[1,2-b]oxet-10-yl benzoate;
Catalogue No.:PA 03 0011001
Molecular Weight : 835.94
Cabazitaxel Impurity (DeTroc-oxazolidine)
Catalogue No.:PA 03 0011002
Molecular Formula : C46H57NO14
Molecular Weight : 847.96
(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-Acetoxy-9-(((2R,3S)-3-((tert-butoxycarbonyl)amino)-2-hydroxy-3-phenylpropanoyl)oxy)-11-hydroxy-4,6-dimethoxy-4a,8,13,13-tetramethyl-5-oxotetradecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxet-12-yl benzoate
Catalogue No.:PA 03 0011003
Molecular Formula : C45H59NO14
Molecular Weight : 837.96
(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-Acetoxy-9-(((2R,3S)-3-(N-(tert-butoxycarbonyl)pivalamido)-2-hydroxy-3-phenylpropanoyl)oxy)-11-hydroxy-4,6-dimethoxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxet-12-yl benzoate
Catalogue No.:PA 03 0011005
Molecular Formula : C50H65NO15
Molecular Weight : 920.06
(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-Acetoxy-9-(((2S,3R)-3-((tert-butoxycarbonyl)amino)-2-((2-methoxypropan-2-yl)oxy)-3-phenylpropanoyl)oxy)-11-hydroxy-4,6-dimethoxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxet-12-yl benzoate
Catalogue No.:PA 03 0011006
Molecular Formula : C49H65NO15
Molecular Weight : 908.05
(3R,4S)-3-((2-methoxypropan-2-yl)oxy)-4-phenylazetidin-2-one
Catalogue No.:PA 03 0011007
Molecular Formula : C13H17NO3
Molecular Weight : 235.28
(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-Acetoxy-9-(((2R,3S)-3-((tert-butoxycarbonyl)amino)-2-((2-methoxypropan-2-yl)oxy)-3-phenylpropanoyl)oxy)-11-hydroxy-4,6-dimethoxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxet-12-yl benzoate
Catalogue No.:PA 03 0011008
(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-Acetoxy-4,6,9,11-tetramethoxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxet-12-yl benzoate
Catalogue No.:PA 03 0011009
Molecular Formula : C33H44O10
Molecular Weight : 600.71
(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-Acetoxy-9,11-dihydroxy-4,6-dimethoxy-4a,8,13,13-tetramethyl-5-oxotetradecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxet-12-yl benzoate
Catalogue No.:PA 03 0011010
Molecular Formula : C31H42O10
Molecular Weight : 574.67
(4R,5S)-rel-3-Benzoyl-2-(4-methoxyphenyl)-4-phenyl-5-Oxazolidinecarboxylic Acid
Catalogue No.:PA 03 0011011
Molecular Formula : C24H21NO5
Molecular Weight : 403.43
(4S,5S)-3-Benzoyl-2-(4-methoxyphenyl)-4-phenyloxazolidine-5-carboxylic acid
Catalogue No.:PA 03 0011012
(2S,4S,5S)-3-(Tert-butoxycarbonyl)-2-(4-methoxyphenyl)-4-phenyloxazolidine-5-carboxylic acid
Catalogue No.:PA 03 0011013
(4R,5R)-3-Benzoyl-2-(4-anisyl)-4-phenyl-5-oxazolidinecarboxylic acid
Catalogue No.:PA 03 0011014
(3S,4S)-3-Hydroxy-4-phenylazetidin-2-one
Catalogue No.:PA 03 0011015
Molecular Formula : C9H9NO2
Molecular Weight : 163.18
(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12-(Benzoyloxy)-9-(((2R,3S)-3-((tert-butoxycarbonyl)amino)-2-hydroxy-3-phenylpropanoyl)oxy)-11-hydroxy-4-methoxy-4a,8,13,13-tetramethyl-5-oxo-3,4,4a,5,6,9,10,11,12,12a-decahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxete-6,12b(2aH)-diyl diacetate
Catalogue No.:PA 03 0011016
Molecular Formula : C46H57NO15
Molecular Weight : 863.95
(2R,4S,5R)-3-(Tert-butoxycarbonyl)-2-(4-methoxyphenyl)-4-phenyloxazolidine-5-carboxylic acid
Catalogue No.:PA 03 0011017
Sodium (4S,5R)-2-(2,4-dimethoxyphenyl)-3-((2-nitrophenyl)thio)-4-phenyloxazolidine-5-carboxylate
Catalogue No.:PA 03 0011018
Molecular Formula : C24H21N2NaO7S
Molecular Weight : 504.49
3-(tert-Butyl) 5-methyl (2R,4S,5R)-2-(4-methoxyphenyl)-4-phenyloxazolidine-3,5-dicarboxylate
Catalogue No.:PA 03 0011019
Molecular Formula : C23H27NO6
Molecular Weight : 413.47
Tigloyl Cabazitaxel (2-debenzoyl-2-tigloyl-cabazitaxel
Catalogue No.:PA 03 0011020
(9S,12bS)-12b-Acetoxy-9,11-dihydroxy-4,6-dimethoxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxet-12-yl benzoate
Catalogue No.:PA 03 0011021
Molecular Weight : 572.65
(9S,12S,12aR,12bS)-12b-Acetoxy-9-(((2R)-3-((tert-butoxycarbonyl)amino)-2-hydroxy-3-phenylpropanoyl)oxy)-11-hydroxy-4,6-dimethoxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxet-12-yl benzoate
Catalogue No.:PA 03 0011022
Cabazitaxel Monohydrate
Catalogue No.:PA 03 0011023
Molecular Formula : C45H59NO15
Molecular Weight : 853.96
(4R)-10-Deacetyl-7,10-dimethoxy-Baccatin III
Catalogue No.:PA 03 0011024
(2S,4R,5S)-3-(tert-Butoxycarbonyl)-2-(4-methoxyphenyl)-4-phenyloxazolidine-5-carboxylic Acid
Catalogue No.:PA 03 0011025
(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-Acetoxy-6-(((2R,3S)-3-((tert-butoxycarbonyl)amino)-2-hydroxy-3-phenylpropanoyl)oxy)-9-((3-((tert-butoxycarbonyl)amino)-2-hydroxy-3-phenylpropanoyl)oxy)-11-hydroxy-4-methoxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxet-12-yl Benzoate
Catalogue No.:PA 03 0011026
(2S,4S,5R)-3-(tert-Butoxycarbonyl)-2-(4-methoxyphenyl)-4-phenyloxazolidine-5-carboxylic Acid
Catalogue No.:PA 03 0011027
4-(Acetyloxy)-13α-[[(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoyl]oxy]-1,7β,10β-trimethoxy-9-oxo-4α,5β-5,20-epoxytax-11-en-2α-yl Benzoate
Catalogue No.:PA 03 0010030
4-(Acetyloxy)-7α,13α-bis[[(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3- phenylpropanoyl]oxy]-1-hydroxy-10β-methoxy-9-oxo-4α,5β-5,20-epoxytax-11-en-2α-yl Benzoate
Catalogue No.:PA 03 0010040
4-(Acetyloxy)-7β,13α-bis[[(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3- phenylpropanoyl]oxy]-1-hydroxy-10β-methoxy-9-oxo-4α,5β-5,20-epoxytax-11-en-2α-yl Benzoate
Catalogue No.:PA 03 0010050
5-[4-(Acetyloxy)-2α-(benzoyloxy)-1-hydroxy-7β,10β-dimethoxy-9-oxo-4α,5β-5,20-epoxytax11-en-13α-yl] 3-tert-butyl (2S,4S,5R)-2-(4-methoxyphenyl)-4-phenyl-1,3-oxazolidine-3,5-dicarboxylate
Catalogue No.:PA 03 0010080
5-[4-(Acetyloxy)-2α-(benzoyloxy)-1-hydroxy-7β,10β-dimethoxy-9-oxo-4α,5β-5,20-epoxytax11-en-13α-yl] 3-tert-butyl (2R,4S,5S)-2-(4-methoxyphenyl)-4-phenyl-1,3-oxazolidine-3,5-dicarboxylate
Catalogue No.:PA 03 0010060
(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-acetoxy-11-hydroxy-4,6-dimethoxy-4a,8,13,13-tetramethyl-5-oxo-9-((triethylsilyl)oxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxet-12-yl benzoate
Catalogue No.:PA 03 0011028
Molecular Formula : C37H54O10Si
Molecular Weight : 686.91
De-boc Cabazitaxel Hydrochloride
Catalogue No.:PA 03 0011029
Molecular Formula : C40H50ClNO12
Molecular Weight : 772.29
De-boc Cabazitaxel Formate
Catalogue No.:PA 03 0011030
Molecular Formula : C41H51NO14
Molecular Weight : 781.85
rel-(4R,5R)-3-(tert-Butoxycarbonyl)-2-(4-methoxyphenyl)-4-phenyloxazolidine-5-carboxylic Acid
Catalogue No.:PA 03 0011031
Cabazitaxel N-3
Catalogue No.:PA 03 0011032
Molecular Formula : C57H61Cl6NO19
Molecular Weight : 1276.8
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