cabozantinib and its Impurities

Cabozantinib is used in two forms. A capsule form is used since 2012 to treat medullary thyroid cancer and a tablet form is used since 2016 as a second line treatment for renal cell carcinoma.. Reference standards of Cabozantinib API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below

Displaying 56 results for cabozantinib Impurities
Drug Reference Standards & Impurity Synthesis in India
PA 30 62000

Cabozantinib

Cabozantinib

  • Catalogue No.:PA 30 62000

  • CAS :

    849217-68-1

  • Molecular Formula : C28H24FN3O5

  • Molecular Weight : 501.51

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Drug Reference Standards & Impurity Synthesis in India
PA 30 0621002

Cabozantinib Hydroxy Analog

Cabozantinib Hydroxy Analog

  • Catalogue No.:PA 30 0621002

  • CAS :

    13425-93-9

  • Molecular Formula : C11H11NO3

  • Molecular Weight : 205.21

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Drug Reference Standards & Impurity Synthesis in India
PA 30 62540

Cabozantinib Nitro Analog

Cabozantinib Nitro Analog

  • Catalogue No.:PA 30 62540

  • CAS :

    190728-24-6

  • Molecular Formula : C17H14N2O5

  • Molecular Weight : 326.3

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Drug Reference Standards & Impurity Synthesis in India
PA 30 62550

Cabozantinib Amine Analog

Cabozantinib Amine Analog

  • Catalogue No.:PA 30 62550

  • CAS :

    190728-25-7

  • Molecular Formula : C17H16N2O3

  • Molecular Weight : 296.32

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Drug Reference Standards & Impurity Synthesis in India
PA 30 62590

Cabozantinib L-Malate

Cabozantinib L-Malate

  • Catalogue No.:PA 30 62590

  • CAS :

    1140909-48-3

  • Molecular Formula : C32H30FN3O10

  • Molecular Weight : 635.59

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Drug Reference Standards & Impurity Synthesis in India
PA 30 62600

1-((4-Fluorophenyl)carbamoyl)cyclopropanecarboxylic Acid

1-((4-Fluorophenyl)carbamoyl)cyclopropanecarboxylic Acid

  • Catalogue No.:PA 30 62600

  • CAS :

    849217-48-7

  • Molecular Formula : C11H10FNO3

  • Molecular Weight : 223.2

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Drug Reference Standards & Impurity Synthesis in India
PA 30 62610

N-(4-Fluorophenyl)-n'-(4-hydroxyphenyl)cyclopropane-1,1-dicarboxamide

N-(4-Fluorophenyl)-n'-(4-hydroxyphenyl)cyclopropane-1,1-dicarboxamide

  • Catalogue No.:PA 30 62610

  • CAS :

    849217-60-3

  • Molecular Formula : C17H15FN2O3

  • Molecular Weight : 314.31

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Drug Reference Standards & Impurity Synthesis in India
PA 30 62620

Cabozantinib Dimer Impurity

Cabozantinib Dimer Impurity

  • Catalogue No.:PA 30 62620

  • CAS :

    2832439-31-1

  • Molecular Formula : C36H30N4O8

  • Molecular Weight : 646.65

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Drug Reference Standards & Impurity Synthesis in India
PA 30 0621000

4-Fluoroaniline Hydrochloride

4-Fluoroaniline Hydrochloride

  • Catalogue No.:PA 30 0621000

  • CAS :

    2146-07-8

  • Molecular Formula : C6H7ClFN

  • Molecular Weight : 147.58

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Drug Reference Standards & Impurity Synthesis in India
PA 30 0621001

3,4-Dimethoxyaniline Hydrochloride

3,4-Dimethoxyaniline Hydrochloride

  • Catalogue No.:PA 30 0621001

  • CAS :

    35589-32-3

  • Molecular Formula : C8H12ClNO2

  • Molecular Weight : 189.64

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Drug Reference Standards & Impurity Synthesis in India
PA 30 0621004

Cabozantinib Carboxylic Acid Analog

Cabozantinib Carboxylic Acid Analog

  • Catalogue No.:PA 30 0621004

  • CAS :

    849217-77-2

  • Molecular Formula : C22H20N2O6

  • Molecular Weight : 408.4

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Drug Reference Standards & Impurity Synthesis in India
PA 30 0621005

N,N'-Bis(4-fluorophenyl)cyclopropane-1,1-dicarboxamide;

N,N'-Bis(4-fluorophenyl)cyclopropane-1,1-dicarboxamide;

  • Catalogue No.:PA 30 0621005

  • CAS :

    1431468-36-8

  • Molecular Formula : C17H14F2N2O2

  • Molecular Weight : 316.31

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Drug Reference Standards & Impurity Synthesis in India
PA 30 0621006

Cabozantinib Desfluoro Impurity

Cabozantinib Desfluoro Impurity

  • Catalogue No.:PA 30 0621006

  • CAS :

    849221-94-9

  • Molecular Formula : C28H25N3O5

  • Molecular Weight : 483.52

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Drug Reference Standards & Impurity Synthesis in India
PA 30 0621010

1-((4-((7-Methoxy-6-(sulfooxy)quinolin-4-yl)oxy)phenyl)carbamoyl)cyclopropane-1-carboxylic Acid

1-((4-((7-Methoxy-6-(sulfooxy)quinolin-4-yl)oxy)phenyl)carbamoyl)cyclopropane-1-carboxylic Acid

  • Catalogue No.:PA 30 0621010

  • CAS :

    1628530-37-9

  • Molecular Formula : C21H18N2O9S

  • Molecular Weight : 474.44

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Drug Reference Standards & Impurity Synthesis in India
PA 30 0621011

N-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)-N-(4-fluoro-2-hydroxyphenyl)cyclopropane-1,1-dicarboxamide

N-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)-N-(4-fluoro-2-hydroxyphenyl)cyclopropane-1,1-dicarboxamide

  • Catalogue No.:PA 30 0621011

  • CAS :

    1628530-38-0

  • Molecular Formula : C28H24FN3O6

  • Molecular Weight : 517.51

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Drug Reference Standards & Impurity Synthesis in India
PA 30 0621013

N,N'-bis(4-((6,7-dimethoxyquinolin-4-yl)oxy)phenyl)cyclopropane-1,1-dicarboxamide

N,N'-bis(4-((6,7-dimethoxyquinolin-4-yl)oxy)phenyl)cyclopropane-1,1-dicarboxamide

  • Catalogue No.:PA 30 0621013

  • CAS :

    2439164-91-5

  • Molecular Formula : C39H34N4O8

  • Molecular Weight : 686.72

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Drug Reference Standards & Impurity Synthesis in India
PA 30 0621012

N-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)-N-(2-fluorophenyl)cyclopropane-1,1-dicarboxamide

N-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)-N-(2-fluorophenyl)cyclopropane-1,1-dicarboxamide

  • Catalogue No.:PA 30 0621012

  • CAS :

    3052225-80-3

  • Molecular Formula : C28H24FN3O5

  • Molecular Weight : 501.51

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Drug Reference Standards & Impurity Synthesis in India
PA 30 0621003

Cabozantinib N-oxide

Cabozantinib N-oxide

  • Catalogue No.:PA 30 0621003

  • CAS :

    1621681-63-7

  • Molecular Formula : C28H24FN3O6

  • Molecular Weight : 517.51

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Drug Reference Standards & Impurity Synthesis in India
PA 30 0621007

4-Chloro-6,7-dimethoxyquinoline

4-Chloro-6,7-dimethoxyquinoline

  • Catalogue No.:PA 30 0621007

  • CAS :

    35654-56-9

  • Molecular Formula : C11H10ClNO2

  • Molecular Weight : 223.66

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Drug Reference Standards & Impurity Synthesis in India
PA 30 0621008

Methyl 1-((4-((6,7-dimethoxyquinolin-4-yl)oxy)phenyl)carbamoyl)cyclopropane-1-carboxylate

Methyl 1-((4-((6,7-dimethoxyquinolin-4-yl)oxy)phenyl)carbamoyl)cyclopropane-1-carboxylate

  • Catalogue No.:PA 30 0621008

  • CAS :

    1584696-82-1

  • Molecular Formula : C23H22N2O6

  • Molecular Weight : 422.44

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Drug Reference Standards & Impurity Synthesis in India
PA 30 0621009

Ethyl 1-((4-((6,7-dimethoxyquinolin-4-yl)oxy)phenyl)carbamoyl)cyclopropane-1-carboxylate

Ethyl 1-((4-((6,7-dimethoxyquinolin-4-yl)oxy)phenyl)carbamoyl)cyclopropane-1-carboxylate

  • Catalogue No.:PA 30 0621009

  • CAS :

    1584696-80-9

  • Molecular Formula : C24H24N2O6

  • Molecular Weight : 436.46

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Drug Reference Standards & Impurity Synthesis in India
PA 30 0621014

N-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)-N-(3-fluorophenyl)cyclopropane-1,1-dicarboxamide

N-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)-N-(3-fluorophenyl)cyclopropane-1,1-dicarboxamide

  • Catalogue No.:PA 30 0621014

  • CAS :

    NA

  • Molecular Formula : C28H24FN3O5

  • Molecular Weight : 501.51

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Drug Reference Standards & Impurity Synthesis in India
PA STI 089396

Cabozantinib-d4

Cabozantinib-d4

  • Catalogue No.:PA STI 089396

  • CAS :

    1802168-53-1

  • Molecular Formula : C28H20D4FN3O5

  • Molecular Weight : 505.54

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Drug Reference Standards & Impurity Synthesis in India
PA 30 0621015

6,7-Dimethoxy-4-(2-nitrophenoxy)quinoline

6,7-Dimethoxy-4-(2-nitrophenoxy)quinoline

  • Catalogue No.:PA 30 0621015

  • CAS :

    190728-26-8

  • Molecular Formula : C17H14N2O5

  • Molecular Weight : 326.31

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Drug Reference Standards & Impurity Synthesis in India
PA 30 0621016

3-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline

3-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline

  • Catalogue No.:PA 30 0621016

  • CAS :

    202917-04-2

  • Molecular Formula : C17H16N2O3

  • Molecular Weight : 296.33

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Drug Reference Standards & Impurity Synthesis in India
PA 30 0621017

6,7-Dimethoxy-4-(3-nitrophenoxy)quinoline

6,7-Dimethoxy-4-(3-nitrophenoxy)quinoline

  • Catalogue No.:PA 30 0621017

  • CAS :

    202917-05-3

  • Molecular Formula : C17H14N2O5

  • Molecular Weight : 326.31

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Drug Reference Standards & Impurity Synthesis in India
PA 30 0621018

1-(Phenylcarbamoyl)cyclopropane-1-carboxylic Acid

1-(Phenylcarbamoyl)cyclopropane-1-carboxylic Acid

  • Catalogue No.:PA 30 0621018

  • CAS :

    145591-80-6

  • Molecular Formula : C11H11NO3

  • Molecular Weight : 205.21

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Drug Reference Standards & Impurity Synthesis in India
PA 30 0621019

1-((3-Fluorophenyl)carbamoyl)cyclopropane-1-carboxylic Acid

1-((3-Fluorophenyl)carbamoyl)cyclopropane-1-carboxylic Acid

  • Catalogue No.:PA 30 0621019

  • CAS :

    1247859-37-5

  • Molecular Formula : C11H10FNO3

  • Molecular Weight : 223.2

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Drug Reference Standards & Impurity Synthesis in India
PA 30 0621020

1-((2-Fluorophenyl)carbamoyl)cyclopropane-1-carboxylic Acid

1-((2-Fluorophenyl)carbamoyl)cyclopropane-1-carboxylic Acid

  • Catalogue No.:PA 30 0621020

  • CAS :

    918642-61-2

  • Molecular Formula : C11H10FNO3

  • Molecular Weight : 223.2

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Drug Reference Standards & Impurity Synthesis in India
PA 30 0621021

2-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline

2-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline

  • Catalogue No.:PA 30 0621021

  • CAS :

    190728-27-9

  • Molecular Formula : C17H16N2O3

  • Molecular Weight : 296.33

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Drug Reference Standards & Impurity Synthesis in India
PA 30 0621022

N-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)-6,7-dimethoxyquinolin-4-amine

N-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)-6,7-dimethoxyquinolin-4-amine

  • Catalogue No.:PA 30 0621022

  • CAS :

    NA

  • Molecular Formula : C28H25N3O5

  • Molecular Weight : 483.52

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Drug Reference Standards & Impurity Synthesis in India
PA 30 0621023

3,4-Dimethoxyaniline

3,4-Dimethoxyaniline

  • Catalogue No.:PA 30 0621023

  • CAS :

    6315-89-5

  • Molecular Formula : C8H11NO2

  • Molecular Weight : 153.18

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Drug Reference Standards & Impurity Synthesis in India
PA 30 0621024

N-(4-Fluorophenyl)-N-(4-((7-hydroxy-6-methoxyquinolin-4-yl)oxy)phenyl)cyclopropane-1,1-dicarboxamide

N-(4-Fluorophenyl)-N-(4-((7-hydroxy-6-methoxyquinolin-4-yl)oxy)phenyl)cyclopropane-1,1-dicarboxamide

  • Catalogue No.:PA 30 0621024

  • CAS :

    1628530-42-6

  • Molecular Formula : C27H22FN3O5

  • Molecular Weight : 487.49

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Drug Reference Standards & Impurity Synthesis in India
PA 30 0621025

N-(4-Fluorophenyl)-N-(4-((6-hydroxy-7-methoxyquinolin-4-yl)oxy)phenyl)cyclopropane-1,1-dicarboxamide

N-(4-Fluorophenyl)-N-(4-((6-hydroxy-7-methoxyquinolin-4-yl)oxy)phenyl)cyclopropane-1,1-dicarboxamide

  • Catalogue No.:PA 30 0621025

  • CAS :

    1628530-47-1

  • Molecular Formula : C27H22FN3O5

  • Molecular Weight : 487.49

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Drug Reference Standards & Impurity Synthesis in India
PA 30 0621026

4-(4-Aminophenoxy)-6-methoxyquinolin-7-ol

4-(4-Aminophenoxy)-6-methoxyquinolin-7-ol

  • Catalogue No.:PA 30 0621026

  • CAS :

    1355031-15-0

  • Molecular Formula : C16H14N2O3

  • Molecular Weight : 282.3

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Drug Reference Standards & Impurity Synthesis in India
PA 30 0621027

4-(4-Aminophenoxy)-7-methoxyquinolin-6-ol

4-(4-Aminophenoxy)-7-methoxyquinolin-6-ol

  • Catalogue No.:PA 30 0621027

  • CAS :

    1628530-35-7

  • Molecular Formula : C16H14N2O3

  • Molecular Weight : 282.3

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Drug Reference Standards & Impurity Synthesis in India
PA 30 0621028

1-((3,4-Difluorophenyl)carbamoyl)cyclopropane-1-carboxylic Acid

1-((3,4-Difluorophenyl)carbamoyl)cyclopropane-1-carboxylic Acid

  • Catalogue No.:PA 30 0621028

  • CAS :

    1275738-77-6

  • Molecular Formula : C11H9F2NO3

  • Molecular Weight : 241.19

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Drug Reference Standards & Impurity Synthesis in India
PA 30 0621029

Methyl 1-((4-fluorophenyl)carbamoyl)cyclopropane-1-carboxylate

Methyl 1-((4-fluorophenyl)carbamoyl)cyclopropane-1-carboxylate

  • Catalogue No.:PA 30 0621029

  • CAS :

    1345847-71-3

  • Molecular Formula : C12H12FNO3

  • Molecular Weight : 237.23

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Drug Reference Standards & Impurity Synthesis in India
PA 30 0621030

(2S,3S,4S,5R,6S)-6-((4-(4-(1-((4-Fluorophenyl)carbamoyl)cyclopropane-1-carboxamido)phenoxy)-6-methoxyquinolin-7-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic Acid

(2S,3S,4S,5R,6S)-6-((4-(4-(1-((4-Fluorophenyl)carbamoyl)cyclopropane-1-carboxamido)phenoxy)-6-methoxyquinolin-7-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic Acid

  • Catalogue No.:PA 30 0621030

  • CAS :

    NA

  • Molecular Formula : C33H30FN3O11

  • Molecular Weight : 663.61

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Drug Reference Standards & Impurity Synthesis in India
PA 30 0621031

4-((6,7-Dimethoxyquinolin-4-yl)amino)phenol

4-((6,7-Dimethoxyquinolin-4-yl)amino)phenol

  • Catalogue No.:PA 30 0621031

  • CAS :

    748707-58-6

  • Molecular Formula : C17H16N2O3

  • Molecular Weight : 296.33

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Drug Reference Standards & Impurity Synthesis in India
PA 30 0621032

(E)-N-(3-(4,5-Dimethoxy-2-nitrophenyl)-3-oxoprop-1-en-1-yl)-N-methylnitrous amide

(E)-N-(3-(4,5-Dimethoxy-2-nitrophenyl)-3-oxoprop-1-en-1-yl)-N-methylnitrous amide

  • Catalogue No.:PA 30 0621032

  • CAS :

    NA

  • Molecular Formula : C12H13N3O6

  • Molecular Weight : 295.25

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Drug Reference Standards & Impurity Synthesis in India
PA 30 0621033

4-((4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)amino)-3-((4-fluorophenyl)carbamoyl)-4-oxobutyl (Z)-N-(4-((6,7-dimethoxyquinolin-4-yl)oxy)phenyl)-1-((4-fluorophenyl)carbamoyl)cyclopropane-1-carbimidate

4-((4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)amino)-3-((4-fluorophenyl)carbamoyl)-4-oxobutyl (Z)-N-(4-((6,7-dimethoxyquinolin-4-yl)oxy)phenyl)-1-((4-fluorophenyl)carbamoyl)cyclopropane-1-carbimidate

  • Catalogue No.:PA 30 0621033

  • CAS :

    NA

  • Molecular Formula : C56H48F2N6O10

  • Molecular Weight : 1003.03

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Drug Reference Standards & Impurity Synthesis in India
PA 30 0621034

5-(((3,4-Dimethoxyphenyl)amino)methylene)-2,2-dimethyl-1,3-dioxane-4,6-dione

5-(((3,4-Dimethoxyphenyl)amino)methylene)-2,2-dimethyl-1,3-dioxane-4,6-dione

  • Catalogue No.:PA 30 0621034

  • CAS :

    213699-53-7

  • Molecular Formula : C15H17NO6

  • Molecular Weight : 307.3

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Drug Reference Standards & Impurity Synthesis in India
PA 30 0621035

Cabozantinib Methyl Ester Analog

Cabozantinib Methyl Ester Analog

  • Catalogue No.:PA 30 0621035

  • CAS :

    1584696-82-1

  • Molecular Formula : C23H22N2O6

  • Molecular Weight : 422.43

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Drug Reference Standards & Impurity Synthesis in India
PA 30 0621036

Cabozantinib Ethyl Ester Analog

Cabozantinib Ethyl Ester Analog

  • Catalogue No.:PA 30 0621036

  • CAS :

    1584696-80-9

  • Molecular Formula : C24H24N2O6

  • Molecular Weight : 436.46

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Drug Reference Standards & Impurity Synthesis in India
PA STI 089763

Cabozantinib-D6

Cabozantinib-D6

  • Catalogue No.:PA STI 089763

  • CAS :

    1802168-46-2

  • Molecular Formula : C28H18D6FN3O5

  • Molecular Weight : 507.55

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Drug Reference Standards & Impurity Synthesis in India
PA 30 0621037

N1-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)-N3-(4-fluorophenyl)-2-(2-hydroxyethyl)malonamide

N1-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)-N3-(4-fluorophenyl)-2-(2-hydroxyethyl)malonamide

  • Catalogue No.:PA 30 0621037

  • CAS :

    NA

  • Molecular Formula : C28H26FN3O6

  • Molecular Weight : 519.53

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Drug Reference Standards & Impurity Synthesis in India
PA 30 0621038

(2S)-4-(4-((4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)amino)-3-((4-fluorophenyl)carbamoyl)-4-oxobutoxy)-2-hydroxy-4-oxobutanoic Acid

(2S)-4-(4-((4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)amino)-3-((4-fluorophenyl)carbamoyl)-4-oxobutoxy)-2-hydroxy-4-oxobutanoic Acid

  • Catalogue No.:PA 30 0621038

  • CAS :

    NA

  • Molecular Formula : C32H30FN3O10

  • Molecular Weight : 635.6

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Drug Reference Standards & Impurity Synthesis in India
PA BSC 06230258

Cabozantinib L-Malate Salt (BSC)

Cabozantinib L-Malate Salt

  • Catalogue No.:PA BSC 06230258

  • CAS :

    1140909-48-3

  • Molecular Formula : C32H30FN3O10

  • Molecular Weight : 635.6

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PA 30 0621039

N-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)-N-(4-fluorophenyl)-N-methylcyclopropane-1,1-dicarboxamide

N-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)-N-(4-fluorophenyl)-N-methylcyclopropane-1,1-dicarboxamide

  • Catalogue No.:PA 30 0621039

  • CAS :

    2458244-61-4

  • Molecular Formula : C29H26FN3O5

  • Molecular Weight : 515.54

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PA 30 0621040

N,N'-Bis(4-fluorophenyl)oxamide

N,N'-Bis(4-fluorophenyl)oxamide

  • Catalogue No.:PA 30 0621040

  • CAS :

    10197-51-0

  • Molecular Formula : C14H10F2N2O2

  • Molecular Weight : 276.24

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PA 30 0621041

Desfluoro Chloro Cabozantinib

Desfluoro Chloro Cabozantinib

  • Catalogue No.:PA 30 0621041

  • CAS :

    NA

  • Molecular Formula : C28H24ClN3O5

  • Molecular Weight : 517.97

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PA 30 0621042

N-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)acetamide

N-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)acetamide

  • Catalogue No.:PA 30 0621042

  • CAS :

    651054-52-3

  • Molecular Formula : C19H18N2O4

  • Molecular Weight : 338.36

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PA 30 0621043

N-Nitroso Cabozantinib

N-Nitroso Cabozantinib

  • Catalogue No.:PA 30 0621043

  • CAS :

    NA

  • Molecular Formula : C28H23FN4O6

  • Molecular Weight : 530.51

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PA 30 0621044

N-(6,7-dimethoxyquinolin-4-yl)-N-(4-hydroxyphenyl)nitrous amide

N-(6,7-dimethoxyquinolin-4-yl)-N-(4-hydroxyphenyl)nitrous amide

  • Catalogue No.:PA 30 0621044

  • CAS :

    NA

  • Molecular Formula : C17H15N3O4

  • Molecular Weight : 325.32

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PA 30 0621045

N-(3,4-dimethoxyphenyl)-N-((2,2-dimethyl-4,6-dioxo-1,3-dioxan-5-ylidene)methyl)nitrous amide

N-(3,4-dimethoxyphenyl)-N-((2,2-dimethyl-4,6-dioxo-1,3-dioxan-5-ylidene)methyl)nitrous amide

  • Catalogue No.:PA 30 0621045

  • CAS :

    NA

  • Molecular Formula : C15H16N2O7

  • Molecular Weight : 336.30

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