Cabozantinib-impurities | Pharmaffiliates

cabozantinib and its Impurities

Cabozantinib is used in two forms. A capsule form is used since 2012 to treat medullary thyroid cancer and a tablet form is used since 2016 as a second line treatment for renal cell carcinoma.. Reference standards of Cabozantinib API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below

Displaying 45 results for cabozantinib Impurities
PA 30 62000

Cabozantinib - API Standards

Cabozantinib


  • Catalogue No.:PA 30 62000

  • CAS :

    849217-68-1

  • Molecular Formula : C28H24FN3O5

  • Molecular Weight : 501.51

PA 30 0621002

Cabozantinib Hydroxy Analog

Cabozantinib Hydroxy Analog


  • Catalogue No.:PA 30 0621002

  • CAS :

    13425-93-9

  • Molecular Formula : C11H11NO3

  • Molecular Weight : 205.21

PA 30 62540

Cabozantinib Nitro Analog

Cabozantinib Nitro Analog


  • Catalogue No.:PA 30 62540

  • CAS :

    190728-24-6

  • Molecular Formula : C17H14N2O5

  • Molecular Weight : 326.3

PA 30 62550

Cabozantinib Amine Analog

Cabozantinib Amine Analog


  • Catalogue No.:PA 30 62550

  • CAS :

    190728-25-7

  • Molecular Formula : C17H16N2O3

  • Molecular Weight : 296.32

PA 30 62590

Cabozantinib L-Malate Salt

Cabozantinib L-Malate Salt


  • Catalogue No.:PA 30 62590

  • CAS :

    1140909-48-3

  • Molecular Formula : C32H30FN3O10

  • Molecular Weight : 635.59

PA 30 62600

1-((4-Fluorophenyl)carbamoyl)cyclopropanecarboxylic Acid

1-((4-Fluorophenyl)carbamoyl)cyclopropanecarboxylic Acid


  • Catalogue No.:PA 30 62600

  • CAS :

    849217-48-7

  • Molecular Formula : C11H10FNO3

  • Molecular Weight : 223.2

PA 30 62610

N-(4-Fluorophenyl)-n'-(4-hydroxyphenyl)cyclopropane-1,1-dicarboxamide

N-(4-Fluorophenyl)-n'-(4-hydroxyphenyl)cyclopropane-1,1-dicarboxamide


  • Catalogue No.:PA 30 62610

  • CAS :

    849217-60-3

  • Molecular Formula : C17H15FN2O3

  • Molecular Weight : 314.31

PA 30 62620

N1,N2-Bis(4-((6,7-dimethoxyquinolin-4-yl)oxy)phenyl)oxalamide

N1,N2-Bis(4-((6,7-dimethoxyquinolin-4-yl)oxy)phenyl)oxalamide


  • Catalogue No.:PA 30 62620

  • CAS :

    NA

  • Molecular Formula : C36H30N4O8

  • Molecular Weight : 646.65

PA 30 0621000

4-Fluoroaniline Hydrochloride

4-Fluoroaniline Hydrochloride


  • Catalogue No.:PA 30 0621000

  • CAS :

    2146-07-8

  • Molecular Formula : C6H7ClFN

  • Molecular Weight : 147.58

PA 30 0621001

3,4-Dimethoxyaniline Hydrochloride

3,4-Dimethoxyaniline Hydrochloride


  • Catalogue No.:PA 30 0621001

  • CAS :

    35589-32-3

  • Molecular Formula : C8H12ClNO2

  • Molecular Weight : 189.64

PA 30 0621004

Cabozantinib Carboxylic Acid Analog

Cabozantinib Carboxylic Acid Analog


  • Catalogue No.:PA 30 0621004

  • CAS :

    849217-77-2

  • Molecular Formula : C22H20N2O6

  • Molecular Weight : 408.4

PA 30 0621005

N,N'-Bis(4-fluorophenyl)cyclopropane-1,1-dicarboxamide;

N,N'-Bis(4-fluorophenyl)cyclopropane-1,1-dicarboxamide;


  • Catalogue No.:PA 30 0621005

  • CAS :

    1431468-36-8

  • Molecular Formula : C17H14F2N2O2

  • Molecular Weight : 316.31

PA 30 0621006

Cabozantinib Desfluoro Impurity

Cabozantinib Desfluoro Impurity


  • Catalogue No.:PA 30 0621006

  • CAS :

    849221-94-9

  • Molecular Formula : C28H25N3O5

  • Molecular Weight : 483.52

PA 30 0621010

1-((4-((7-Methoxy-6-(sulfooxy)quinolin-4-yl)oxy)phenyl)carbamoyl)cyclopropane-1-carboxylic Acid

1-((4-((7-Methoxy-6-(sulfooxy)quinolin-4-yl)oxy)phenyl)carbamoyl)cyclopropane-1-carboxylic Acid


  • Catalogue No.:PA 30 0621010

  • CAS :

    1628530-37-9

  • Molecular Formula : C21H18N2O9S

  • Molecular Weight : 474.44

PA 30 0621011

N-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)-N-(4-fluoro-2-hydroxyphenyl)cyclopropane-1,1-dicarboxamide

N-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)-N-(4-fluoro-2-hydroxyphenyl)cyclopropane-1,1-dicarboxamide


  • Catalogue No.:PA 30 0621011

  • CAS :

    1628530-38-0

  • Molecular Formula : C28H24FN3O6

  • Molecular Weight : 517.51

PA 30 0621013

N,N'-bis(4-((6,7-dimethoxyquinolin-4-yl)oxy)phenyl)cyclopropane-1,1-dicarboxamide

N,N'-bis(4-((6,7-dimethoxyquinolin-4-yl)oxy)phenyl)cyclopropane-1,1-dicarboxamide


  • Catalogue No.:PA 30 0621013

  • CAS :

    2439164-91-5

  • Molecular Formula : C39H34N4O8

  • Molecular Weight : 686.72

PA 30 0621012

N-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)-N-(2-fluorophenyl)cyclopropane-1,1-dicarboxamide

N-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)-N-(2-fluorophenyl)cyclopropane-1,1-dicarboxamide


  • Catalogue No.:PA 30 0621012

  • CAS :

    NA

  • Molecular Formula : C28H24FN3O5

  • Molecular Weight : 501.51

PA 30 0621003

Cabozantinib N-oxide

Cabozantinib N-oxide


  • Catalogue No.:PA 30 0621003

  • CAS :

    1621681-63-7

  • Molecular Formula : C28H24FN3O6

  • Molecular Weight : 517.51

PA 30 0621007

4-Chloro-6,7-dimethoxyquinoline

4-Chloro-6,7-dimethoxyquinoline


  • Catalogue No.:PA 30 0621007

  • CAS :

    35654-56-9

  • Molecular Formula : C11H10ClNO2

  • Molecular Weight : 223.66

PA 30 0621008

Methyl 1-((4-((6,7-dimethoxyquinolin-4-yl)oxy)phenyl)carbamoyl)cyclopropane-1-carboxylate

Methyl 1-((4-((6,7-dimethoxyquinolin-4-yl)oxy)phenyl)carbamoyl)cyclopropane-1-carboxylate


  • Catalogue No.:PA 30 0621008

  • CAS :

    1584696-82-1

  • Molecular Formula : C23H22N2O6

  • Molecular Weight : 422.44

PA 30 0621009

Ethyl 1-((4-((6,7-dimethoxyquinolin-4-yl)oxy)phenyl)carbamoyl)cyclopropane-1-carboxylate

Ethyl 1-((4-((6,7-dimethoxyquinolin-4-yl)oxy)phenyl)carbamoyl)cyclopropane-1-carboxylate


  • Catalogue No.:PA 30 0621009

  • CAS :

    1584696-80-9

  • Molecular Formula : C24H24N2O6

  • Molecular Weight : 436.46

PA 30 0621014

N-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)-N-(3-fluorophenyl)cyclopropane-1,1-dicarboxamide

N-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)-N-(3-fluorophenyl)cyclopropane-1,1-dicarboxamide


  • Catalogue No.:PA 30 0621014

  • CAS :

    NA

  • Molecular Formula : C28H24FN3O5

  • Molecular Weight : 501.51

PA STI 089396

Cabozantinib-d4

Cabozantinib-d4


  • Catalogue No.:PA STI 089396

  • CAS :

    1802168-53-1

  • Molecular Formula : C28H20D4FN3O5

  • Molecular Weight : 505.54

PA 30 0621015

6,7-Dimethoxy-4-(2-nitrophenoxy)quinoline

6,7-Dimethoxy-4-(2-nitrophenoxy)quinoline


  • Catalogue No.:PA 30 0621015

  • CAS :

    190728-26-8

  • Molecular Formula : C17H14N2O5

  • Molecular Weight : 326.31

PA 30 0621016

3-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline

3-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline


  • Catalogue No.:PA 30 0621016

  • CAS :

    202917-04-2

  • Molecular Formula : C17H16N2O3

  • Molecular Weight : 296.33

PA 30 0621017

6,7-Dimethoxy-4-(3-nitrophenoxy)quinoline

6,7-Dimethoxy-4-(3-nitrophenoxy)quinoline


  • Catalogue No.:PA 30 0621017

  • CAS :

    202917-05-3

  • Molecular Formula : C17H14N2O5

  • Molecular Weight : 326.31

PA 30 0621018

1-(Phenylcarbamoyl)cyclopropane-1-carboxylic Acid

1-(Phenylcarbamoyl)cyclopropane-1-carboxylic Acid


  • Catalogue No.:PA 30 0621018

  • CAS :

    145591-80-6

  • Molecular Formula : C11H11NO3

  • Molecular Weight : 205.21

PA 30 0621019

1-((3-Fluorophenyl)carbamoyl)cyclopropane-1-carboxylic Acid

1-((3-Fluorophenyl)carbamoyl)cyclopropane-1-carboxylic Acid


  • Catalogue No.:PA 30 0621019

  • CAS :

    1247859-37-5

  • Molecular Formula : C11H10FNO3

  • Molecular Weight : 223.2

PA 30 0621020

1-((2-Fluorophenyl)carbamoyl)cyclopropane-1-carboxylic Acid

1-((2-Fluorophenyl)carbamoyl)cyclopropane-1-carboxylic Acid


  • Catalogue No.:PA 30 0621020

  • CAS :

    918642-61-2

  • Molecular Formula : C11H10FNO3

  • Molecular Weight : 223.2

PA 30 0621021

2-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline

2-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline


  • Catalogue No.:PA 30 0621021

  • CAS :

    190728-27-9

  • Molecular Formula : C17H16N2O3

  • Molecular Weight : 296.33

PA 30 0621022

N-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)-6,7-dimethoxyquinolin-4-amine

N-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)-6,7-dimethoxyquinolin-4-amine


  • Catalogue No.:PA 30 0621022

  • CAS :

    NA

  • Molecular Formula : C28H25N3O5

  • Molecular Weight : 483.52

PA 30 0621023

3,4-Dimethoxyaniline

3,4-Dimethoxyaniline


  • Catalogue No.:PA 30 0621023

  • CAS :

    6315-89-5

  • Molecular Formula : C8H11NO2

  • Molecular Weight : 153.18

PA 30 0621024

N-(4-Fluorophenyl)-N-(4-((7-hydroxy-6-methoxyquinolin-4-yl)oxy)phenyl)cyclopropane-1,1-dicarboxamide

N-(4-Fluorophenyl)-N-(4-((7-hydroxy-6-methoxyquinolin-4-yl)oxy)phenyl)cyclopropane-1,1-dicarboxamide


  • Catalogue No.:PA 30 0621024

  • CAS :

    1628530-42-6

  • Molecular Formula : C27H22FN3O5

  • Molecular Weight : 487.49

PA 30 0621025

N-(4-Fluorophenyl)-N-(4-((6-hydroxy-7-methoxyquinolin-4-yl)oxy)phenyl)cyclopropane-1,1-dicarboxamide

N-(4-Fluorophenyl)-N-(4-((6-hydroxy-7-methoxyquinolin-4-yl)oxy)phenyl)cyclopropane-1,1-dicarboxamide


  • Catalogue No.:PA 30 0621025

  • CAS :

    1628530-47-1

  • Molecular Formula : C27H22FN3O5

  • Molecular Weight : 487.49

PA 30 0621026

4-(4-Aminophenoxy)-6-methoxyquinolin-7-ol

4-(4-Aminophenoxy)-6-methoxyquinolin-7-ol


  • Catalogue No.:PA 30 0621026

  • CAS :

    1355031-15-0

  • Molecular Formula : C16H14N2O3

  • Molecular Weight : 282.3

PA 30 0621027

4-(4-Aminophenoxy)-7-methoxyquinolin-6-ol

4-(4-Aminophenoxy)-7-methoxyquinolin-6-ol


  • Catalogue No.:PA 30 0621027

  • CAS :

    1628530-35-7

  • Molecular Formula : C16H14N2O3

  • Molecular Weight : 282.3

PA 30 0621028

1-((3,4-Difluorophenyl)carbamoyl)cyclopropane-1-carboxylic Acid

1-((3,4-Difluorophenyl)carbamoyl)cyclopropane-1-carboxylic Acid


  • Catalogue No.:PA 30 0621028

  • CAS :

    1275738-77-6

  • Molecular Formula : C11H9F2NO3

  • Molecular Weight : 241.19

PA 30 0621029

Methyl 1-((4-fluorophenyl)carbamoyl)cyclopropane-1-carboxylate

Methyl 1-((4-fluorophenyl)carbamoyl)cyclopropane-1-carboxylate


  • Catalogue No.:PA 30 0621029

  • CAS :

    1345847-71-3

  • Molecular Formula : C12H12FNO3

  • Molecular Weight : 237.23

PA 30 0621030

(2S,3S,4S,5R,6S)-6-((4-(4-(1-((4-Fluorophenyl)carbamoyl)cyclopropane-1-carboxamido)phenoxy)-6-methoxyquinolin-7-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic Acid

(2S,3S,4S,5R,6S)-6-((4-(4-(1-((4-Fluorophenyl)carbamoyl)cyclopropane-1-carboxamido)phenoxy)-6-methoxyquinolin-7-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic Acid


  • Catalogue No.:PA 30 0621030

  • CAS :

    NA

  • Molecular Formula : C33H30FN3O11

  • Molecular Weight : 663.61

PA 30 0621031

4-((6,7-Dimethoxyquinolin-4-yl)amino)phenol

4-((6,7-Dimethoxyquinolin-4-yl)amino)phenol


  • Catalogue No.:PA 30 0621031

  • CAS :

    748707-58-6

  • Molecular Formula : C17H16N2O3

  • Molecular Weight : 296.33

PA 30 0621032

(E)-N-(3-(4,5-Dimethoxy-2-nitrophenyl)-3-oxoprop-1-en-1-yl)-N-methylnitrous amide

(E)-N-(3-(4,5-Dimethoxy-2-nitrophenyl)-3-oxoprop-1-en-1-yl)-N-methylnitrous amide


  • Catalogue No.:PA 30 0621032

  • CAS :

    NA

  • Molecular Formula : C12H13N3O6

  • Molecular Weight : 295.25

PA 30 0621033

4-((4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)amino)-3-((4-fluorophenyl)carbamoyl)-4-oxobutyl (Z)-N-(4-((6,7-dimethoxyquinolin-4-yl)oxy)phenyl)-1-((4-fluorophenyl)carbamoyl)cyclopropane-1-carbimidate

4-((4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)amino)-3-((4-fluorophenyl)carbamoyl)-4-oxobutyl (Z)-N-(4-((6,7-dimethoxyquinolin-4-yl)oxy)phenyl)-1-((4-fluorophenyl)carbamoyl)cyclopropane-1-carbimidate


  • Catalogue No.:PA 30 0621033

  • CAS :

    NA

  • Molecular Formula : C56H48F2N6O10

  • Molecular Weight : 1003.03

PA 30 0621034

5-(((3,4-Dimethoxyphenyl)amino)methylene)-2,2-dimethyl-1,3-dioxane-4,6-dione

5-(((3,4-Dimethoxyphenyl)amino)methylene)-2,2-dimethyl-1,3-dioxane-4,6-dione


  • Catalogue No.:PA 30 0621034

  • CAS :

    213699-53-7

  • Molecular Formula : C15H17NO6

  • Molecular Weight : 307.3

PA 30 0621035

Cabozantinib Methyl Ester Analog

Cabozantinib Methyl Ester Analog


  • Catalogue No.:PA 30 0621035

  • CAS :

    1584696-82-1

  • Molecular Formula : C23H22N2O6

  • Molecular Weight : 422.43

PA 30 0621036

Cabozantinib Ethyl Ester Analog

Cabozantinib Ethyl Ester Analog


  • Catalogue No.:PA 30 0621036

  • CAS :

    1584696-80-9

  • Molecular Formula : C24H24N2O6

  • Molecular Weight : 436.46