Calcium Levofolinate Pentahydrate and its Impurities
Levoleucovorin injection is in a class of medications called folic acid analogs. It works to prevent the harmful effects of methotrexate by protecting healthy cells, while allowing methotrexate to enter and kill cancer cells. It works to treat colorectal cancer by increasing the effects of fluorouracil. Reference standards of Calcium Levofolinate Pentahydrate API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.


(4-((((R)-2-Amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl)methyl)(nitroso)amino)benzoyl)-L-glutamic acid
(4-((((R)-2-Amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl)methyl)(nitroso)amino)benzoyl)-L-glutamic acid
Catalogue No.:PA 03 3641000
CAS :
NA
Molecular Formula : C20H22N8O8
Molecular Weight : 502.44


(4-((((S)-2-Amino-5-formyl-8-nitroso-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl)methyl)amino)benzoyl)-L-glutamic acid
(4-((((S)-2-Amino-5-formyl-8-nitroso-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl)methyl)amino)benzoyl)-L-glutamic acid
Catalogue No.:PA 03 3641001
CAS :
NA
Molecular Formula : C20H22N8O8
Molecular Weight : 502.44