Carboprost and its Impurities
Carboprost (INN, trade names for the tromethamine salts Hemabate, Tham) is a synthetic prostaglandin analogue. Carboprost tromethamine is a prostaglandin used to treat postpartum uterine hemorrhage due to atony. Reference standards of Carboprost API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
Methyl (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((R,E)-3-hydroxy-3-methyloct-1-en-1-yl)cyclopentyl)hept-5-enoate
Methyl (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((R,E)-3-hydroxy-3-methyloct-1-en-1-yl)cyclopentyl)hept-5-enoate
Catalogue No.:PA 56 0921000
CAS :
35700-22-2
Molecular Formula : C22H38O5
Molecular Weight : 382.54
Methyl (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((1E,3E)-3-methylocta-1,3-dien-1-yl)cyclopentyl)hept-5-enoate
Methyl (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((1E,3E)-3-methylocta-1,3-dien-1-yl)cyclopentyl)hept-5-enoate
Catalogue No.:PA 56 0921001
CAS :
94805-69-3
Molecular Formula : C22H36O4
Molecular Weight : 364.53
Methyl (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((E)-3-methoxy-3-methyloct-1-en-1-yl)cyclopentyl)hept-5-enoate
Methyl (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((E)-3-methoxy-3-methyloct-1-en-1-yl)cyclopentyl)hept-5-enoate
Catalogue No.:PA 56 0921002
CAS :
94805-68-2
Molecular Formula : C23H40O5
Molecular Weight : 396.57
Methyl (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((S,E)-1-methoxy-3-methyloct-2-en-1-yl)cyclopentyl)hept-5-enoate
Methyl (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((S,E)-1-methoxy-3-methyloct-2-en-1-yl)cyclopentyl)hept-5-enoate
Catalogue No.:PA 56 0921003
CAS :
NA
Molecular Formula : C23H40O5
Molecular Weight : 396.57
(Z)-7-((1R,2R,3R,5S)-3,5-Dihydroxy-2-((1E,3E)-3-methylocta-1,3-dien-1-yl)cyclopentyl)hept-5-enoic acid
(Z)-7-((1R,2R,3R,5S)-3,5-Dihydroxy-2-((1E,3E)-3-methylocta-1,3-dien-1-yl)cyclopentyl)hept-5-enoic acid
Catalogue No.:PA 56 0921004
CAS :
56328-67-7
Molecular Formula : C21H34O4
Molecular Weight : 350.5
(Z)-7-((1R,2R,3R,5S)-3,5-Dihydroxy-2-((E)-1-hydroxy-3-methyloct-2-en-1-yl)cyclopentyl)hept-5-enoic acid
(Z)-7-((1R,2R,3R,5S)-3,5-Dihydroxy-2-((E)-1-hydroxy-3-methyloct-2-en-1-yl)cyclopentyl)hept-5-enoic acid
Catalogue No.:PA 56 0921005
CAS :
NA
Molecular Formula : C21H36O5
Molecular Weight : 368.51
(3aR,4R,5R,6aS)-4-((E)-3-Hydroxy-3-methyloct-1-en-1-yl)-2-oxohexahydro-2H-cyclopenta[b]furan-5-yl [1,1'-biphenyl]-4-carboxylate
(3aR,4R,5R,6aS)-4-((E)-3-Hydroxy-3-methyloct-1-en-1-yl)-2-oxohexahydro-2H-cyclopenta[b]furan-5-yl [1,1'-biphenyl]-4-carboxylate
Catalogue No.:PAI 56 092001
CAS :
2418538-08-4
Molecular Formula : C29H34O5
Molecular Weight : 462.59
(3aR,4R,5R,6aS)-2-Hydroxy-4-((E)-3-hydroxy-3-methyloct-1-en-1-yl)hexahydro-2H-cyclopenta[b]furan-5-yl [1,1'-biphenyl]-4-carboxylate
(3aR,4R,5R,6aS)-2-Hydroxy-4-((E)-3-hydroxy-3-methyloct-1-en-1-yl)hexahydro-2H-cyclopenta[b]furan-5-yl [1,1'-biphenyl]-4-carboxylate
Catalogue No.:PAI 56 092002
CAS :
2418538-08-4
Molecular Formula : C29H36O5
Molecular Weight : 464.6
(3aR,4R,5R,6aS)-4-((E)-3-Hydroxy-3-methyloct-1-en-1-yl)hexahydro-2H-cyclopenta[b]furan-2,5-diol
(3aR,4R,5R,6aS)-4-((E)-3-Hydroxy-3-methyloct-1-en-1-yl)hexahydro-2H-cyclopenta[b]furan-2,5-diol
Catalogue No.:PAI 56 092003
CAS :
2418538-10-8
Molecular Formula : C16H28O4
Molecular Weight : 284.4
Methyl (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((S,E)-3-hydroxyoct-1-en-1-yl)cyclopentyl)hept-5-enoate
Methyl (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((S,E)-3-hydroxyoct-1-en-1-yl)cyclopentyl)hept-5-enoate
Catalogue No.:PA 03 4151000
CAS :
33854-16-9
Molecular Formula : C21H36O5
Molecular Weight : 368.51
