carfilzomib and its Impurities

Carfilzomib is derived from epoxomicin, a natural product that was shown by the laboratory of Craig Crews at Yale University to inhibit the proteasome. It is an anti-cancer drug acting as a selective proteasome inhibitor. Chemically, it is a tetrapeptide epoxyketone and an analog of epoxomicin.. Reference standards of Carfilzomib API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below

Displaying 12 results for carfilzomib Impurities
Drug Reference Standards & Impurity Synthesis in India
PA 30 0631072

(S)-3-Amino-4-(((S)-1-carboxy-3-phenylpropyl)amino)-4-oxobutanoic Acid

(S)-3-Amino-4-(((S)-1-carboxy-3-phenylpropyl)amino)-4-oxobutanoic Acid


  • Catalogue No.:PA 30 0631072

  • CAS :

    NA

  • Molecular Formula : C14H18N2O5

  • Molecular Weight : 294.31

Drug Reference Standards & Impurity Synthesis in India
PA 30 0631073

(2R,4S)-1-((3H-[1,2,3]Triazolo[4,5-b]pyridin-3-yl)oxy)-4-amino-2-hydroxy-2,6-dimethylheptan-3-one

(2R,4S)-1-((3H-[1,2,3]Triazolo[4,5-b]pyridin-3-yl)oxy)-4-amino-2-hydroxy-2,6-dimethylheptan-3-one


  • Catalogue No.:PA 30 0631073

  • CAS :

    NA

  • Molecular Formula : C14H21N5O3

  • Molecular Weight : 307.35

Drug Reference Standards & Impurity Synthesis in India
PA 30 0631074

(S)-N-Methoxy-N,4-dimethyl-2-((S)-2-((S)-4-methyl-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamido)-3-phenylpropanamido)pentanamide

(S)-N-Methoxy-N,4-dimethyl-2-((S)-2-((S)-4-methyl-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamido)-3-phenylpropanamido)pentanamide


  • Catalogue No.:PA 30 0631074

  • CAS :

    NA

  • Molecular Formula : C39H58N6O7

  • Molecular Weight : 722.93

Drug Reference Standards & Impurity Synthesis in India
PA 30 0631075

(R)-4-Methyl-N-((S)-1-(((R)-4-methyl-1-((S)-2-methyloxiran-2-yl)-1-oxopentan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)-2-((R)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide

(R)-4-Methyl-N-((S)-1-(((R)-4-methyl-1-((S)-2-methyloxiran-2-yl)-1-oxopentan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)-2-((R)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide


  • Catalogue No.:PA 30 0631075

  • CAS :

    NA

  • Molecular Formula : C40H57N5O7

  • Molecular Weight : 719.92

Drug Reference Standards & Impurity Synthesis in India
PA 30 0631076

(S)-2-Amino-N-methoxy-N,4-dimethylpentanamide

(S)-2-Amino-N-methoxy-N,4-dimethylpentanamide


  • Catalogue No.:PA 30 0631076

  • CAS :

    102837-29-6

  • Molecular Formula : C8H18N2O2

  • Molecular Weight : 174.24

Drug Reference Standards & Impurity Synthesis in India
PA 30 0631077

4-Methyl-2-(2-(2-morpholinoacetamido)-4-phenylbutanamido)-N-(1-oxo-3-phenyl-1-((1,2,2-trihydroxy-6-methyl-3-oxoheptan-4-yl)amino)propan-2-yl)pentanamide

4-Methyl-2-(2-(2-morpholinoacetamido)-4-phenylbutanamido)-N-(1-oxo-3-phenyl-1-((1,2,2-trihydroxy-6-methyl-3-oxoheptan-4-yl)amino)propan-2-yl)pentanamide


  • Catalogue No.:PA 30 0631077

  • CAS :

    NA

  • Molecular Formula : C39H57N5O9

  • Molecular Weight : 739.91

Drug Reference Standards & Impurity Synthesis in India
PA 30 0631078

4-Methyl-N-(1-((4-methyl-1-(2-methyloxiran-2-yl)-1-oxopentan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)-2-(2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide

4-Methyl-N-(1-((4-methyl-1-(2-methyloxiran-2-yl)-1-oxopentan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)-2-(2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide


  • Catalogue No.:PA 30 0631078

  • CAS :

    NA

  • Molecular Formula : C40H57N5O7

  • Molecular Weight : 719.92

Drug Reference Standards & Impurity Synthesis in India
PA 30 0631079

((S)-2-((tert-Butoxycarbonyl)amino)-4-phenylbutanoyl)-L-aspartic Acid

((S)-2-((tert-Butoxycarbonyl)amino)-4-phenylbutanoyl)-L-aspartic Acid


  • Catalogue No.:PA 30 0631079

  • CAS :

    NA

  • Molecular Formula : C19H26N2O7

  • Molecular Weight : 394.42

Drug Reference Standards & Impurity Synthesis in India
PA 30 0631080

2-((2S,5S)-3,6-Dioxo-5-phenethylpiperazin-2-yl)acetic Acid

2-((2S,5S)-3,6-Dioxo-5-phenethylpiperazin-2-yl)acetic Acid


  • Catalogue No.:PA 30 0631080

  • CAS :

    NA

  • Molecular Formula : C14H16N2O4

  • Molecular Weight : 276.29

Drug Reference Standards & Impurity Synthesis in India
PA 30 0631081

((S)-2-Amino-4-phenylbutanoyl)-L-aspartic Acid

((S)-2-Amino-4-phenylbutanoyl)-L-aspartic Acid


  • Catalogue No.:PA 30 0631081

  • CAS :

    3066865-52-6

  • Molecular Formula : C14H18N2O5

  • Molecular Weight : 294.31

Drug Reference Standards & Impurity Synthesis in India
PA 30 0631082

N4-((S)-1-carboxy-3-phenylpropyl)-L-asparagine

N4-((S)-1-carboxy-3-phenylpropyl)-L-asparagine


  • Catalogue No.:PA 30 0631082

  • CAS :

    NA

  • Molecular Formula : C14H18N2O5

  • Molecular Weight : 294.31

Drug Reference Standards & Impurity Synthesis in India
PA 30 0631083

(S)-2-((S)-2-((tert-Butoxycarbonyl)amino)-4-phenylbutanamido)-4-phenylbutanoic Acid

(S)-2-((S)-2-((tert-Butoxycarbonyl)amino)-4-phenylbutanamido)-4-phenylbutanoic Acid


  • Catalogue No.:PA 30 0631083

  • CAS :

    NA

  • Molecular Formula : C25H32N2O5

  • Molecular Weight : 440.54

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