caspofungin diacetate and its Impurities
Caspofungin Diacetate is an acetate salt and an antibiotic antifungal drug Caspofungin acetate is the diacetate salt of caspofungin. It is used for the treatment of invasive candidiasis, and of aspergillosis in patients who are refractory to, or intolerant of, other therapy. It has a role as an antiinfective agent.. Reference standards of Caspofungin Diacetate API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below
Caspofungin Acetate Impurity 1
N-[(10R,12S)-10,12-dimethyltetradecanoyl]-(4R,5Ξ)-4,5-dihydroxy-L-prolyl-L-threonyl-(4R)-4-hydroxy-L-prolyl-(4S)-4-hydroxy-4-(4-hydroxyphenyl)-L-threonyl-(3R)-3-hydroxy-L-ornithyl-(3S)-3-hydroxyprolinamide
Catalogue No.:PA 30 0101004
CAS :
NA
Molecular Formula : C50H82N8O16
Molecular Weight : 1051.25
(10R,12S)-N-((2R,6S,9S,11R,14aS,15S,20S,23S,25aS,E)-20-((R)-3-Amino-1-hydroxypropyl)-23-((1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl)-2,11,15-trihydroxy-6-((R)-1-hydroxyethyl)-5,8,14,19,22,25-hexaoxo-2,3,5,6,7,8,9,10,11,14,14a,15,16,17,19,20,21,22,23,24,25,25a-docosahydro-1H-dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13,16]hexaazacyclohenicosin-9-yl)-10,12-dimethyltetradecanamide
(10R,12S)-N-((2R,6S,9S,11R,14aS,15S,20S,23S,25aS,E)-20-((R)-3-Amino-1-hydroxypropyl)-23-((1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl)-2,11,15-trihydroxy-6-((R)-1-hydroxyethyl)-5,8,14,19,22,25-hexaoxo-2,3,5,6,7,8,9,10,11,14,14a,15,16,17,19,20,21,22,23,24,25,25a-docosahydro-1H-dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13,16]hexaazacyclohenicosin-9-yl)-10,12-dimethyltetradecanamide
Catalogue No.:PA PEP 001177
CAS :
NA
Molecular Formula : C50H80N8O15
Molecular Weight : 1033.23
