Caspofungin is a lipopeptide antifungal drug from Merck & Co., Inc. discovered by James Balkovec, Regina Black and Frances A Bouffard. It is used to treat a variety of serious fungal infections.. Reference standards of Caspofungin API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below
Caspofungin
Catalogue No.:PA 30 87000
CAS :
Molecular Formula : C52H88N10O15
Molecular Weight : 1093.31
(3S)-(4R,5S)-5-[(2-Aminoethyl)amino]-N2-[(10R,12S)-10,12-dimethyl-1-oxotetradecyl]-4-hydroxy-L-ornithyl-L-seryl-(4R)-4-hydroxy-L-prolyl-(4S)-4-hydroxy-4-(4-hydroxyphenyl)-L-threonyl-(3R)-3-hydroxy-L-ornithyl-3-hydroxy-L-proline
Catalogue No.:PA 30 10510
Molecular Formula : C51H86N10O15
Molecular Weight : 1079.29
Pneumocandin B0
Catalogue No.:PA 30 10520
Molecular Formula : C50H80N8O17
Molecular Weight : 1065.21
Caspofungin Pneumocandin C0 Impurity
Catalogue No.:PA 30 10530
Caspofungin C0 Analog
Catalogue No.:PA 30 10540
N-((6S,10S,14aS,20S,23S,25aS)-20-((R)-3-Amino-1-hydroxypropyl)-12-((2-aminoethyl)amino)-23-((1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl)-2,11-dihydroxy-6-(1-hydroxyethyl)-5,8,14,19,22,25-hexaoxotetracosahydro-1H-dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13,16]hexaazacyclohenicosin-10-yl)-10,12-dimethyltetradecanamide
Catalogue No.:PA 30 10550
Molecular Formula : C52H88N10O14
Molecular Weight : 1077.31
Caspofungin Dimer 1
Catalogue No.:PA 30 10560
Molecular Formula : C102H170N18O30
Molecular Weight : 2128.54
Caspofungin Dimer 2
Catalogue No.:PA 30 10570
Molecular Formula : C102H170N18O29
Molecular Weight : 2112.54
Caspofungin Phenylthio Amide Impurity
Catalogue No.:PA 30 10580
Molecular Formula : C56H84N8O16S
Molecular Weight : 1157.38
Caspofungin Phenylthio Amine Impurity
Catalogue No.:PA 30 10590
Molecular Formula : C56H86N8O15S
Molecular Weight : 1143.39
5-Des(2-aminoethylamino)-5-hydroxy-4,5-seco-5,9-cyclo Caspofungin
Catalogue No.:PA 30 10600
Molecular Formula : C50H82N8O16
Molecular Weight : 1051.23
(10R,12S)-N-((2R,6S,9S,11R,12R,14aS,15S,20S,23S,25aS)-20-((R)-3-Amino-1-hydroxypropyl)-12-((2-aminoethyl)amino)-23-((1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl)-2,11,15-trihydroxy-6-((R)-1-hydroxyethyl)-5,8,14,19,22,25-hexaoxotetracosahydro-1H-dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13,16]hexaazacyclohenicosin-9-yl)-10,12-dimethyltetradecanamide
Catalogue No.:PA 30 10610
(10R,12S)-N-((2R,6S,9S,11R,12R,14aS,15S,20S,23S,25aS)-20-((R)-3-Amino-1-hydroxypropyl)-23-((1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl)-2,11,12,15-tetrahydroxy-6-((R)-1-hydroxyethyl)-5,8,14,19,22,25-hexaoxotetracosahydro-1H-dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13,16]hexaazacyclohenicosin-9-yl)-10,12-dimethyltetradecanamide
Catalogue No.:PA 30 10620
(10R,12S)-N-((2R,6R,9S,11R,12S,14aS,16R,20S,23S,25aR)-20-((R)-3-Amino-1-hydroxypropyl)-12-((2-aminoethyl)amino)-23-((1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl)-2,11,16-trihydroxy-6-((R)-1-hydroxyethyl)-5,8,14,19,22,25-hexaoxotetracosahydro-1H-dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13,16]hexaazacyclohenicosin-9-yl)-10,12-dimethyltetradecanamide
Catalogue No.:PA 30 10630
(3R,5aS,6S,11S,14S,16S,16aS,18R,22S,24aR)-11-((R)-3-Amino-1-hydroxypropyl)-14-((1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl)-1-((10R,12S)-10,12-dimethyltetradecanoyl)-2,3,6,16,18-pentahydroxy-22-((R)-1-hydroxyethyl)icosahydrotripyrrolo[2,1-c:2',1'-l:2'',3''-r][1,4,7,10,13,16]hexaazacyclononadecine-5,10,13,21,24(14H)-pentaone
Catalogue No.:PA 30 10640
(10R,12S)-N-((2R,6S,9S,11R,12R,14aS,15S,20S,23S,25aS)-20-((R)-3-Amino-1-hydroxy-3-oxopropyl)-23-((1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl)-2,11,15-trihydroxy-6-((R)-1-hydroxyethyl)-5,8,14,19,22,25-hexaoxo-12-(phenylthio)tetracosahydro-1H-dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13,16]hexaazacyclohenicosin-9-yl)-10,12-dimethyltetradecanamide
Catalogue No.:PA 30 10650
(10R,12S)-N-((2R,6S,9S,11R,12R,14aS,15S,20S,23S,25aS)-20-((R)-3-Amino-1-hydroxypropyl)-23-((1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl)-2,11,15-trihydroxy-6-((R)-1-hydroxyethyl)-5,8,14,19,22,25-hexaoxo-12-(phenylthio)tetracosahydro-1H-dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13,16]hexaazacyclohenicosin-9-yl)-10,12-dimethyltetradecanamide
Catalogue No.:PA 30 10660
Caspofungin Acetate-d4
Catalogue No.:PA STI 018151
Molecular Formula : C56H92D4N10O19
Molecular Weight : 1217.44
Caspofungin-d4
Catalogue No.:PA STI 018153
Molecular Formula : C52H84D4N10O15
Molecular Weight : 1097.36
(10R,12S)-N-((2R,6S,9S,11R,12S,14aS,15S,20S,23S,25aS)-20-((R)-3-Amino-1-hydroxypropyl)-12-((2-aminoethyl)amino)-23-((1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl)-2,11,15-trihydroxy-6-(hydroxymethyl)-5,8,14,19,22,25-hexaoxotetracosahydro-1H-dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13,16]hexaazacyclohenicosin-9-yl)-10,12-dimethyltetradecanamide Diacetate
Catalogue No.:PA 30 10680
Molecular Formula : C55H94N10O19
Molecular Weight : 1199.41
2-Ethylhexyl 2-(((2R,6S,9S,11R,12R,14aS,15S,20S,23S,25aS)-20-((R)-3-amino-1-hydroxypropyl)-23-((1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl)-9-((10R,12S)-10,12-dimethyltetradecanamido)-2,11,15-trihydroxy-6-((R)-1-hydroxyethyl)-5,8,14,19,22,25-hexaoxotetracosahydro-1H-dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13,16]hexaazacyclohenicosin-12-yl)thio)acetate Acetate
Catalogue No.:PA 30 10690
Molecular Formula : C62H104N8O19S
Molecular Weight : 1297.61
N-((2R,9S,11R,12R,14aS,20S,25aS)-20-((R)-3-Amino-1-hydroxy-3-oxopropyl)-23-((1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl)-2,11,12-trihydroxy-6-((R)-1-hydroxyethyl)-5,8,14,19,22,25-hexaoxotetracosahydro-1H-dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13,16]hexaazacyclohenicosin-9-yl)-10,12-dimethyltetradecanamide
Catalogue No.:PA 30 10700
Molecular Formula : C50H80N8O16
Molecular Weight : 1049.23
(10S,12R)-N-((2R,6S,9S,12R,14aS,15S,20S,25aS)-20-((R)-3-amino-1-hydroxy-3-oxopropyl)-23-((1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl)-2,12,15-trihydroxy-6-((R)-1-hydroxyethyl)-5,8,14,19,22,25-hexaoxotetracosahydro-1H-dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13,16]hexaazacyclohenicosin-9-yl)-10,12-dimethyltetradecanamide
Catalogue No.:PA 30 10710
N-((2R,6S,9S,11R,12S,14aS,15S,20S,23S,25aS)-20-((S)-3-Amino-1-hydroxypropyl)-12-((2-aminoethyl)(hydroxy)amino)-23-((1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl)-2,11,15-trihydroxy-6-((R)-1-hydroxyethyl)-5,8,14,19,22,25-hexaoxotetracosahydro-1H-dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13,16]hexaazacyclohenicosin-9-yl)-10,12-dimethyltetradecanamide
Catalogue No.:PA 30 0101000
Molecular Formula : C52H88N10O16
Molecular Weight : 1109.33
N5-Hydroxylamino Caspofungin
Catalogue No.:PA 30 0101001
Molecular Formula : C54H92N10O18
Molecular Weight : 1109.31
(10R,12S)-N-((2R,6S,9S,11R,12S,14aS,15S,20S,23S,25aS)-20-((R)-3-Amino-1-hydroxy-3-oxopropyl)-12-((2-aminoethyl)amino)-23-((1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl)-2,11,15-trihydroxy-6-((R)-1-hydroxyethyl)-5,8,14,19,22,25-hexaoxotetracosahydro-1H-dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13,16]hexaazacyclohenicosin-9-yl)-10,12-dimethyltetradecanamide Acetate
Catalogue No.:PA 30 0101002
Molecular Formula : C54H90N10O18
Molecular Weight : 1167.37
(10R,12S)-N-((2R,6S,9S,11R,12R,14aS,16R,20S,23S,25aS)-20-((R)-3-Amino-1-hydroxypropyl)-12-((2-aminoethyl)amino)-23-((1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl)-2,11,16-trihydroxy-6-((R)-1-hydroxyethyl)-5,8,14,19,22,25-hexaoxotetracosahydro-1H-dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13,16]hexaazacyclohenicosin-9-yl)-10,12-dimethyltetradecanamide
Catalogue No.:PA 30 0871000
Molecular Weight : 1093.33
(2R,4R)-N-((2S,3R)-1-((2S,4R)-2-(((2S,3S,4S)-1-(((2S,3R)-5-Amino-1-((2S,3S)-2-carbamoyl-3-hydroxypyrrolidin-1-yl)-3-hydroxy-1-oxopentan-2-yl)amino)-3,4-dihydroxy-4-(4-hydroxyphenyl)-1-oxobutan-2-yl)carbamoyl)-4-hydroxypyrrolidin-1-yl)-3-hydroxy-1-oxobutan-2-yl)-1-((10R,12S)-10,12-dimethyltetradecanoyl)-4,5-dihydroxypyrrolidine-2-carboxamide
Catalogue No.:PA 30 0871001
Molecular Weight : 1051.25
(2R,4R)-N-((2S,3R)-1-((2S,4R)-2-(((2S,3S,4S)-1-(((2S,3R)-5-Amino-1-((2S,3S)-2-carbamoyl-3-hydroxypyrrolidin-1-yl)-3-hydroxy-1-oxopentan-2-yl)amino)-3,4-dihydroxy-4-(4-hydroxyphenyl)-1-oxobutan-2-yl)carbamoyl)-4-hydroxypyrrolidin-1-yl)-3-hydroxy-1-oxobutan-2-yl)-1-((10R,12S)-10,12-dimethyltetradecanoyl)-4,5-dihydroxypyrrolidine-2-carboxamide Acetate
Catalogue No.:PA 30 0871002
Molecular Formula : C52H86N8O18
Molecular Weight : 1111.3
N-((2R,6S,9S,11R,12R,14aS,15S,20S,23S,25aS)-20-((R)-3-Amino-1-hydroxypropyl)-23-((1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl)-2,11,12,15-tetrahydroxy-6-((R)-1-hydroxyethyl)-5,8,14,19,22,25-hexaoxotetracosahydro-1H-dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13,16]hexaazacyclohenicosin-9-yl)-10,12-dimethyltetradecanamide
Catalogue No.:PA 30 0871003
N-((2R,6S,9S,11R,12S,14aS,15S,20S,23S,25aS)-20-((R)-3-Amino-1-hydroxypropyl)-12-((2-aminoethyl)amino)-23-((1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl)-2,11,15-trihydroxy-6-(hydroxymethyl)-5,8,14,19,22,25-hexaoxotetracosahydro-1H-dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13,16]hexaazacyclohenicosin-9-yl)-10,12-dimethyltetradecanamide
Catalogue No.:PA 30 0871004
Molecular Weight : 1079.3
Caspofungin Hydroxylamine Impurity
Catalogue No.:PA 30 0871005
Caspofungin Nitroso Impurity
Catalogue No.:PA 30 0871006
Molecular Formula : C52H87N11O16
Molecular Weight : 1122.33
Pneumocandin B0 Serine Analog
Catalogue No.:PA 30 0871007
Molecular Formula : C49H78N8O17
Molecular Weight : 1051.2
Caspofungin Impurity 12
Catalogue No.:PA 30 0871008
Molecular Formula : C102H166N18O29
Molecular Weight : 2108.55
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