cetirizine and its Impurities
Cetirizine is sold under the brand name Zyrtec among others, is a second generation antihistamine used to treat allergic rhinitis (hay fever), dermatitis, and urticaria.. Reference standards of Cetirizine API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below


((2R,3R,4S,5R,6S)-3,4,5-Trihydroxy-6-(((2R,3S,4R,5R,6R)-4,5,6-trihydroxy-2-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)oxy)tetrahydro-2H-pyran-2-yl)methyl 2-(2-(4-((4-chlorophenyl)(phenyl)methyl)piperazin-1-yl)ethoxy)acetate Hydrochloride
((2R,3R,4S,5R,6S)-3,4,5-Trihydroxy-6-(((2R,3S,4R,5R,6R)-4,5,6-trihydroxy-2-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)oxy)tetrahydro-2H-pyran-2-yl)methyl 2-(2-(4-((4-chlorophenyl)(phenyl)methyl)piperazin-1-yl)ethoxy)acetate Hydrochloride
Catalogue No.:PA 30 51530
CAS :
NA
Molecular Formula : C33H46Cl2N2O13
Molecular Weight : 749.63


Cetirizine Related Compound B (2-(4-Benzhydrylpiperazin-1-yl)ethan-1-ol dihydrochloride) (1102941)
Cetirizine Related Compound B (2-(4-Benzhydrylpiperazin-1-yl)ethan-1-ol dihydrochloride) (1102941)
Catalogue No.:PA USP1102941
CAS :
108983-83-1
Molecular Formula : NA
Molecular Weight : NA


Cetirizine Related Compound A ((RS)-2-[2-[4-[(4-chlorophenyl)phenylmethyl]piperazin-1-yl]ethoxy]ace (1102930)
Cetirizine Related Compound A ((RS)-2-[2-[4-[(4-chlorophenyl)phenylmethyl]piperazin-1-yl]ethoxy]ace (1102930)
Catalogue No.:PA USP1102930
CAS :
246870-46-2
Molecular Formula : NA
Molecular Weight : NA


Cetirizine Related Compound C (2-(2-{4-[(4-Chlorophenyl)phenylmethyl]piperazin-1-yl}ethoxy)acetamid (1102952)
Cetirizine Related Compound C (2-(2-{4-[(4-Chlorophenyl)phenylmethyl]piperazin-1-yl}ethoxy)acetamid (1102952)
Catalogue No.:PA USP1102952
CAS :
83881-37-2
Molecular Formula : NA
Molecular Weight : NA


Cetirizine Related Compound G (2-{4-[(4-Chlorophenyl)phenylmethyl]piperazin-1-yl}ethanol dihydrochl (1102963)
Cetirizine Related Compound G (2-{4-[(4-Chlorophenyl)phenylmethyl]piperazin-1-yl}ethanol dihydrochl (1102963)
Catalogue No.:PA USP1102963
CAS :
NA
Molecular Formula : NA
Molecular Weight : NA


1-Hydroxypropan-2-yl 2-(2-(4-((R)-(4-chlorophenyl)(phenyl)methyl)piperazin-1-yl)ethoxy)acetate
1-Hydroxypropan-2-yl 2-(2-(4-((R)-(4-chlorophenyl)(phenyl)methyl)piperazin-1-yl)ethoxy)acetate
Catalogue No.:PAI 03 001513
CAS :
NA
Molecular Formula : C24H31ClN2O4
Molecular Weight : 446.2


(2,2-Dimethyl-1,3-dioxolan-4-yl)methyl 2-(2-(4-((4-chlorophenyl)(phenyl)methyl)piperazin-1-yl)ethoxy)acetate
(2,2-Dimethyl-1,3-dioxolan-4-yl)methyl 2-(2-(4-((4-chlorophenyl)(phenyl)methyl)piperazin-1-yl)ethoxy)acetate
Catalogue No.:PAI 03 001515
CAS :
NA
Molecular Formula : C27H35ClN2O5
Molecular Weight : 503.04


(2S,3S,4R,5R)-2,3,4,5,6-Pentahydroxyhexyl 2-(2-(4-((4-chlorophenyl)(phenyl)methyl)piperazin-1-yl)ethoxy)acetate
(2S,3S,4R,5R)-2,3,4,5,6-Pentahydroxyhexyl 2-(2-(4-((4-chlorophenyl)(phenyl)methyl)piperazin-1-yl)ethoxy)acetate
Catalogue No.:PA 30 0511015
CAS :
NA
Molecular Formula : C27H37ClN2O8
Molecular Weight : 553.05


1-Hydroxypropan-2-yl 2-(2-(4-((4-chlorophenyl)(phenyl)methyl)piperazin-1-yl)ethoxy)acetate compound with 2-hydroxypropyl 2-(2-(4-((4-chlorophenyl)(phenyl)methyl)piperazin-1-yl)ethoxy)acetate (1:1)
1-Hydroxypropan-2-yl 2-(2-(4-((4-chlorophenyl)(phenyl)methyl)piperazin-1-yl)ethoxy)acetate compound with 2-hydroxypropyl 2-(2-(4-((4-chlorophenyl)(phenyl)methyl)piperazin-1-yl)ethoxy)acetate (1:1)
Catalogue No.:PA 30 0511016
CAS :
NA
Molecular Formula : C24H31ClN2O4
Molecular Weight : 446.97