clavulanate potassium and its Impurities
Clavulanate Potassium is a β-lactam drug that functions as a mechanism-based β-lactamase inhibitor. For the treatment of pyelonephritis during pregnancy, and for the treatment of pyelonephritis caused by gram-positive organisms, amoxicillin or amoxicillin-clavulanate potassium is preferred.. Reference standards of Clavulanate Potassium API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below


Clavulanate Potassium - Impurity E
(2R,4R,5Z)-2-(Carboxymethyl)-5-(2-hydroxyethylidene)-3-[[(2R,3Z,5R)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabibyclo[3.2.0]hept-2-yl]carbonyl]oxazolidine-4-carboxylic Acid
Catalogue No.:PA 03 61050
CAS :
1260617-10-4
Molecular Formula : C16H18N2O10
Molecular Weight : 398.32


methyl (2R,4R,Z)-5-(2-hydroxyethylidene)-3-((2R,5R,Z)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carbonyl)-2-(2-methoxy-2-oxoethyl)oxazolidine-4-carboxylate
methyl (2R,4R,Z)-5-(2-hydroxyethylidene)-3-((2R,5R,Z)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carbonyl)-2-(2-methoxy-2-oxoethyl)oxazolidine-4-carboxylate
Catalogue No.:PAI 03 018140
CAS :
NA
Molecular Formula : C18H22N2O10
Molecular Weight : 426.38


4-(((4-(2-Hydroxyethyl)-1H-pyrrole-3-carbonyl)oxy)methyl)-1-(phenylsulfonyl)-1H-pyrrole-3-carboxylic Acid
4-(((4-(2-Hydroxyethyl)-1H-pyrrole-3-carbonyl)oxy)methyl)-1-(phenylsulfonyl)-1H-pyrrole-3-carboxylic Acid
Catalogue No.:PAI 03 018153
CAS :
NA
Molecular Formula : C19H18N2O7S
Molecular Weight : 418.42


(4-(Ethoxycarbonyl)-1-(phenylsulfonyl)-1H-pyrrol-3-yl)methyl 4-(2-((tert-butyldiphenylsilyl)oxy)ethyl)-1-(phenylsulfonyl)-1H-pyrrole-3-carboxylate
(4-(Ethoxycarbonyl)-1-(phenylsulfonyl)-1H-pyrrol-3-yl)methyl 4-(2-((tert-butyldiphenylsilyl)oxy)ethyl)-1-(phenylsulfonyl)-1H-pyrrole-3-carboxylate
Catalogue No.:PAI 03 018157
CAS :
NA
Molecular Formula : C43H44N2O9S2Si
Molecular Weight : 825.04