clobetasol and its Impurities
A corticosteroid , it is used for treating skin problems like eczema and psoriasis. Clobetasol propionate belongs to glucocorticoid class and is available as shampoo, mousse, ointment and emollient cream . Helps in treatment of auto immune diseases like alopecia areata and vitiligo, Reference standards of Clobetasol API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
1-((10R,13S,17R)-17-Hydroxy-10,13-dimethyl-3-(pyrrolidin-1-yl)-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)ethan-1-one
1-((10R,13S,17R)-17-Hydroxy-10,13-dimethyl-3-(pyrrolidin-1-yl)-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)ethan-1-one
Catalogue No.:PAI 03 032010
CAS :
NA
Molecular Formula : C25H39NO2
Molecular Weight : 385.59
2-bromo-1-((10R,13S,17R)-17-hydroxy-10,13-dimethyl-3-(pyrrolidin-1-yl)-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)ethan-1-one
2-bromo-1-((10R,13S,17R)-17-hydroxy-10,13-dimethyl-3-(pyrrolidin-1-yl)-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)ethan-1-one
Catalogue No.:PAI 03 032020
CAS :
NA
Molecular Formula : C25H38BrNO2
Molecular Weight : 464.49
2-((10R,13S,17R)-10,13-Dimethyl-17-(nitrooxy)-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl acetate
2-((10R,13S,17R)-10,13-Dimethyl-17-(nitrooxy)-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl acetate
Catalogue No.:PAI 03 032030
CAS :
NA
Molecular Formula : C23H31NO7
Molecular Weight : 433.50
2-((10R,13S,17R)-10,13-Dimethyl-17-(nitrooxy)-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl acetate
2-((10R,13S,17R)-10,13-Dimethyl-17-(nitrooxy)-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl acetate
Catalogue No.:PAI 03 032040
CAS :
NA
Molecular Formula : C23H31NO7
Molecular Weight : 433.50
2-((10R,13S)-10,13-Dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl Acetate
2-((10R,13S)-10,13-Dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl Acetate
Catalogue No.:PAI 03 032050
CAS :
NA
Molecular Formula : C23H30O4
Molecular Weight : 370.49
2-((6aR,8aS,8bR,11aS)-6a,8a-Dimethyl-4-oxo-1,4,5,6,6a,6b,7,8,8a,11,11a,12,12a,12b-tetradecahydronaphtho[2',1':4,5]indeno[1,2-c]pyrazol-8b(2H)-yl)-2-oxoethyl acetate
2-((6aR,8aS,8bR,11aS)-6a,8a-Dimethyl-4-oxo-1,4,5,6,6a,6b,7,8,8a,11,11a,12,12a,12b-tetradecahydronaphtho[2',1':4,5]indeno[1,2-c]pyrazol-8b(2H)-yl)-2-oxoethyl acetate
Catalogue No.:PAI 03 032060
CAS :
NA
Molecular Formula : C24H32N2O4
Molecular Weight : 412.53
2-Oxo-2-((10R,13S)-10,13,16-Trimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl)ethyl Acetate
2-Oxo-2-((10R,13S)-10,13,16-Trimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl)ethyl Acetate
Catalogue No.:PAI 03 032070
CAS :
NA
Molecular Formula : C24H32O4
Molecular Weight : 384.52
2-Oxo-2-((6aR,8aS,8bS,9aR)-6a,8a,9a-trimethyl-4-oxo-1,2,4,5,6,6a,6b,7,8,8a,9a,10,10a,10b-tetradecahydro-8bH-naphtho[2',1':4,5]indeno[1,2-b]oxiren-8b-yl)ethyl acetate
2-Oxo-2-((6aR,8aS,8bS,9aR)-6a,8a,9a-trimethyl-4-oxo-1,2,4,5,6,6a,6b,7,8,8a,9a,10,10a,10b-tetradecahydro-8bH-naphtho[2',1':4,5]indeno[1,2-b]oxiren-8b-yl)ethyl acetate
Catalogue No.:PAI 03 032080
CAS :
NA
Molecular Formula : C24H32O5
Molecular Weight : 400.52
2-((10R,13S,16S,17R)-17-hydroxy-10,13,16-trimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl acetate
2-((10R,13S,16S,17R)-17-hydroxy-10,13,16-trimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl acetate
Catalogue No.:PAI 03 032090
CAS :
NA
Molecular Formula : C24H34O5
Molecular Weight : 402.53
(10R,13S,16S,17R)-17-Hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one
(10R,13S,16S,17R)-17-Hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one
Catalogue No.:PAI 03 032100
CAS :
NA
Molecular Formula : C22H32O4
Molecular Weight : 360.49
(10R,13S,16S,17R)-17-(2-Hydroxyacetyl)-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl Propionate
(10R,13S,16S,17R)-17-(2-Hydroxyacetyl)-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl Propionate
Catalogue No.:PAI 03 032110
CAS :
NA
Molecular Formula : C25H34O5
Molecular Weight : 414.54
9-Fluoro-11-hydroxy-10,13,16-trimethyl-7,8,9,10,11,12,13,14,15,16-decahydro-3H-cyclopenta[a]phenanthrene-3,17(6H)-dione
9-Fluoro-11-hydroxy-10,13,16-trimethyl-7,8,9,10,11,12,13,14,15,16-decahydro-3H-cyclopenta[a]phenanthrene-3,17(6H)-dione
Catalogue No.:PAI 03 032111
CAS :
NA
Molecular Formula : C20H25FO3
Molecular Weight : 332.42
