Copanlisib and its Impurities
Copanlisib is an inhibitor of phosphoinositide 3-kinase (PI3K) inhibitor with potential antineoplastic activity. It works by targeting the enzyme that plays a role in regulating cell growth and survival. Reference standards of Copanlisib API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
2-Amino-N-(7-(methoxy-d3)-8-(3-morpholinopropoxy)-2,3-dihydroimidazo[1,2-c]quinazolin-5-yl)pyrimidine-5-carboxamide
2-Amino-N-(7-(methoxy-d3)-8-(3-morpholinopropoxy)-2,3-dihydroimidazo[1,2-c]quinazolin-5-yl)pyrimidine-5-carboxamide
Catalogue No.:PA 03 3491000
CAS :
2168537-34-4
Molecular Formula : C23H25D3N8O4
Molecular Weight : 483.55
2-Amino-N-(7-methoxy-8-(3-morpholinopropoxy)-2,3-dihydroimidazo[1,2-c]quinazolin-5-yl-2,2,3,3-d4)pyrimidine-5-carboxamide
2-Amino-N-(7-methoxy-8-(3-morpholinopropoxy)-2,3-dihydroimidazo[1,2-c]quinazolin-5-yl-2,2,3,3-d4)pyrimidine-5-carboxamide
Catalogue No.:PA 03 3491001
CAS :
2168537-44-6
Molecular Formula : C23H24D4N8O4
Molecular Weight : 484.55
2-Amino-N-(7-methoxy-8-(3-morpholinopropoxy-1,1,2,2,3,3-d6)-2,3-dihydroimidazo[1,2-c]quinazolin-5-yl)pyrimidine-5-carboxamide
2-Amino-N-(7-methoxy-8-(3-morpholinopropoxy-1,1,2,2,3,3-d6)-2,3-dihydroimidazo[1,2-c]quinazolin-5-yl)pyrimidine-5-carboxamide
Catalogue No.:PA 03 3491002
CAS :
2168537-40-2
Molecular Formula : C23H22D6N8O4
Molecular Weight : 486.57
2-Amino-N-(7-methoxy-8-(3-(morpholino-d8)propoxy)-2,3-dihydroimidazo[1,2-c]quinazolin-5-yl)pyrimidine-5-carboxamide
2-Amino-N-(7-methoxy-8-(3-(morpholino-d8)propoxy)-2,3-dihydroimidazo[1,2-c]quinazolin-5-yl)pyrimidine-5-carboxamide
Catalogue No.:PA 03 3491003
CAS :
2168537-35-5
Molecular Formula : C23H20D8N8O4
Molecular Weight : 488.58
