crizotinib and its Impurities
Crizotinib is used to treat certain types of lung cancer. It works by slowing or stopping the growth of lung cancer cells. It belongs to a class of drugs known as kinase inhibitors. Reference standards of Crizotinib API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
(R)-3-(1-(2,6-Dichloro-3-fluorophenyl)ethoxy)-5-(1-(1-isopropylpiperidin-4-yl)-1H-pyrazol-4-yl)pyridin-2-amine
(R)-3-(1-(2,6-Dichloro-3-fluorophenyl)ethoxy)-5-(1-(1-isopropylpiperidin-4-yl)-1H-pyrazol-4-yl)pyridin-2-amine
Catalogue No.:PA 03 3851004
CAS :
NA
Molecular Formula : C24H28Cl2FN5O
Molecular Weight : 492.42
(R)-4-(4-(4-(6-Amino-5-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-3-yl)-1H-pyrazol-1-yl)piperidin-1-yl)butan-1-ol
(R)-4-(4-(4-(6-Amino-5-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-3-yl)-1H-pyrazol-1-yl)piperidin-1-yl)butan-1-ol
Catalogue No.:PA 03 3851005
CAS :
NA
Molecular Formula : C25H30Cl2FN5O2
Molecular Weight : 522.45
tert-Butyl (R)-4-(4-(6-amino-5-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-3-yl)-1H-pyrazol-1-yl)piperidine-1-carboxylate
tert-Butyl (R)-4-(4-(6-amino-5-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-3-yl)-1H-pyrazol-1-yl)piperidine-1-carboxylate
Catalogue No.:PA 03 3851006
CAS :
877399-51-4
Molecular Formula : C26H30Cl2FN5O3
Molecular Weight : 550.46
