crizotinib and its Impurities

Crizotinib is used to treat certain types of lung cancer. It works by slowing or stopping the growth of lung cancer cells. It belongs to a class of drugs known as kinase inhibitors. Reference standards of Crizotinib API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

Displaying 49 results for crizotinib Impurities
Drug Reference Standards & Impurity Synthesis in India
PA STI 022770

Crizotinib-d5

Crizotinib-d5

  • Catalogue No.:PA STI 022770

  • CAS :

    1395950-48-7

  • Molecular Formula : C21H17D5Cl2FN5O

  • Molecular Weight : 455.37

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Drug Reference Standards & Impurity Synthesis in India
PA STI 088317

(R)-Crizotinib-d5 (piperidine-3,3,4,5,5-d5)

(R)-Crizotinib-d5 (piperidine-3,3,4,5,5-d5)

  • Catalogue No.:PA STI 088317

  • CAS :

    1395950-84-1

  • Molecular Formula : C21H17D5Cl2FN5O

  • Molecular Weight : 455.37

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Drug Reference Standards & Impurity Synthesis in India
PA 03 3850000

Crizotinib

Crizotinib

  • Catalogue No.:PA 03 3850000

  • CAS :

    877399-52-5

  • Molecular Formula : C21H22Cl2FN5O

  • Molecular Weight : 450.34

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Drug Reference Standards & Impurity Synthesis in India
PA 03 3851000

2-Keto Crizotinib

2-Keto Crizotinib

  • Catalogue No.:PA 03 3851000

  • CAS :

    1415558-82-5

  • Molecular Formula : C21H20Cl2FN5O2

  • Molecular Weight : 464.32

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Drug Reference Standards & Impurity Synthesis in India
PA 03 3851001

(S)-Crizotinib

(S)-Crizotinib

  • Catalogue No.:PA 03 3851001

  • CAS :

    1374356-45-2

  • Molecular Formula : C21H22Cl2FN5O

  • Molecular Weight : 450.34

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Drug Reference Standards & Impurity Synthesis in India
PA 03 3851002

(R,S)-Crizotinib

(R,S)-Crizotinib

  • Catalogue No.:PA 03 3851002

  • CAS :

    877400-66-3

  • Molecular Formula : C21H22Cl2FN5O

  • Molecular Weight : 450.34

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Drug Reference Standards & Impurity Synthesis in India
PA 03 3851003

(R)-5-Bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine

(R)-5-Bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine

  • Catalogue No.:PA 03 3851003

  • CAS :

    877399-00-3

  • Molecular Formula : C13H10BrCl2FN2O

  • Molecular Weight : 380.04

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Drug Reference Standards & Impurity Synthesis in India
PA 03 3851004

(R)-3-(1-(2,6-Dichloro-3-fluorophenyl)ethoxy)-5-(1-(1-isopropylpiperidin-4-yl)-1H-pyrazol-4-yl)pyridin-2-amine

(R)-3-(1-(2,6-Dichloro-3-fluorophenyl)ethoxy)-5-(1-(1-isopropylpiperidin-4-yl)-1H-pyrazol-4-yl)pyridin-2-amine

  • Catalogue No.:PA 03 3851004

  • CAS :

    NA

  • Molecular Formula : C24H28Cl2FN5O

  • Molecular Weight : 492.42

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Drug Reference Standards & Impurity Synthesis in India
PA 03 3851005

(R)-4-(4-(4-(6-Amino-5-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-3-yl)-1H-pyrazol-1-yl)piperidin-1-yl)butan-1-ol

(R)-4-(4-(4-(6-Amino-5-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-3-yl)-1H-pyrazol-1-yl)piperidin-1-yl)butan-1-ol

  • Catalogue No.:PA 03 3851005

  • CAS :

    NA

  • Molecular Formula : C25H30Cl2FN5O2

  • Molecular Weight : 522.45

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Drug Reference Standards & Impurity Synthesis in India
PA 03 3851006

tert-Butyl (R)-4-(4-(6-amino-5-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-3-yl)-1H-pyrazol-1-yl)piperidine-1-carboxylate

tert-Butyl (R)-4-(4-(6-amino-5-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-3-yl)-1H-pyrazol-1-yl)piperidine-1-carboxylate

  • Catalogue No.:PA 03 3851006

  • CAS :

    877399-51-4

  • Molecular Formula : C26H30Cl2FN5O3

  • Molecular Weight : 550.46

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Drug Reference Standards & Impurity Synthesis in India
PA 03 3851007

Crizotinib Amine Impurity

Crizotinib Amine Impurity

  • Catalogue No.:PA 03 3851007

  • CAS :

    877397-71-2

  • Molecular Formula : C13H11Cl2FN2O

  • Molecular Weight : 301.14

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Drug Reference Standards & Impurity Synthesis in India
PA 03 3851008

(R)-4-(4-(6-Amino-5-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-3-yl)-1H-pyrazol-1-yl)piperidin-1-ol

(R)-4-(4-(6-Amino-5-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-3-yl)-1H-pyrazol-1-yl)piperidin-1-ol

  • Catalogue No.:PA 03 3851008

  • CAS :

    NA

  • Molecular Formula : C21H22Cl2FN5O2

  • Molecular Weight : 466.34

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Drug Reference Standards & Impurity Synthesis in India
PA 03 3851009

(R)-3-(1-(2,6-Dichloro-3-fluorophenyl)ethoxy)-5-(1H-pyrazol-4-yl)pyridin-2-amine

(R)-3-(1-(2,6-Dichloro-3-fluorophenyl)ethoxy)-5-(1H-pyrazol-4-yl)pyridin-2-amine

  • Catalogue No.:PA 03 3851009

  • CAS :

    3026867-46-6

  • Molecular Formula : C16H13Cl2FN4O

  • Molecular Weight : 367.21

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Drug Reference Standards & Impurity Synthesis in India
PA 03 3851010

tert-Butyl 4-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)piperidine-1-carboxylate

tert-Butyl 4-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)piperidine-1-carboxylate

  • Catalogue No.:PA 03 3851010

  • CAS :

    877399-74-1

  • Molecular Formula : C19H32BN3O4

  • Molecular Weight : 377.29

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Drug Reference Standards & Impurity Synthesis in India
PAI 03 385001

5-Bromo-2-nitropyridin-3-ol

5-Bromo-2-nitropyridin-3-ol

  • Catalogue No.:PAI 03 385001

  • CAS :

    691872-15-8

  • Molecular Formula : C5H3BrN2O3

  • Molecular Weight : 218.99

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Drug Reference Standards & Impurity Synthesis in India
PAI 03 385002

5-Bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine

5-Bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine

  • Catalogue No.:PAI 03 385002

  • CAS :

    756503-69-2

  • Molecular Formula : C13H10BrCl2FN2O

  • Molecular Weight : 380.04

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Drug Reference Standards & Impurity Synthesis in India
PAI 03 385003

3-(1-(2,6-Dichloro-3-fluorophenyl)ethoxy)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine

3-(1-(2,6-Dichloro-3-fluorophenyl)ethoxy)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine

  • Catalogue No.:PAI 03 385003

  • CAS :

    877399-08-1

  • Molecular Formula : C19H22BCl2FN2O3

  • Molecular Weight : 427.1

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Drug Reference Standards & Impurity Synthesis in India
PA 03 3851011

tert-Butyl 4-(4-(6-amino-5-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-3-yl)-1H-pyrazol-1-yl)piperidine-1-carboxylate

tert-Butyl 4-(4-(6-amino-5-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-3-yl)-1H-pyrazol-1-yl)piperidine-1-carboxylate

  • Catalogue No.:PA 03 3851011

  • CAS :

    877401-42-8

  • Molecular Formula : C26H30Cl2FN5O3

  • Molecular Weight : 550.46

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Drug Reference Standards & Impurity Synthesis in India
PA 03 3851012

3-(1-(2-Chloro-3-fluorophenyl)ethoxy)-5-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)pyridin-2-amine

3-(1-(2-Chloro-3-fluorophenyl)ethoxy)-5-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)pyridin-2-amine

  • Catalogue No.:PA 03 3851012

  • CAS :

    NA

  • Molecular Formula : C21H23ClFN5O

  • Molecular Weight : 415.9

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Drug Reference Standards & Impurity Synthesis in India
PAI 03 385004

5-Bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-2-nitropyridine

5-Bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-2-nitropyridine

  • Catalogue No.:PAI 03 385004

  • CAS :

    2307671-05-0

  • Molecular Formula : C13H8BrCl2FN2O3

  • Molecular Weight : 410.02

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Drug Reference Standards & Impurity Synthesis in India
PAI 03 385005

(S)-5-Bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-2-nitropyridine

(S)-5-Bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-2-nitropyridine

  • Catalogue No.:PAI 03 385005

  • CAS :

    NA

  • Molecular Formula : C13H8BrCl2FN2O3

  • Molecular Weight : 410.02

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Drug Reference Standards & Impurity Synthesis in India
PAI 03 385006

(S)-5-Bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine

(S)-5-Bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine

  • Catalogue No.:PAI 03 385006

  • CAS :

    1448326-33-7

  • Molecular Formula : C13H10BrCl2FN2O

  • Molecular Weight : 380.04

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Drug Reference Standards & Impurity Synthesis in India
PAI 03 385007

tert-Butyl (S)-4-(4-(6-amino-5-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-3-yl)-1H-pyrazol-1-yl)piperidine-1-carboxylate

tert-Butyl (S)-4-(4-(6-amino-5-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-3-yl)-1H-pyrazol-1-yl)piperidine-1-carboxylate

  • Catalogue No.:PAI 03 385007

  • CAS :

    1428476-86-1

  • Molecular Formula : C26H30Cl2FN5O3

  • Molecular Weight : 550.46

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Drug Reference Standards & Impurity Synthesis in India
PA 03 3851014

2-Amino-4-bromopyridin-3-ol

2-Amino-4-bromopyridin-3-ol

  • Catalogue No.:PA 03 3851014

  • CAS :

    114335-54-5

  • Molecular Formula : C5H5BrN2O

  • Molecular Weight : 189.01

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Drug Reference Standards & Impurity Synthesis in India
PA 03 3851015

4-Bromo-2-nitropyridin-3-ol

4-Bromo-2-nitropyridin-3-ol

  • Catalogue No.:PA 03 3851015

  • CAS :

    1805945-97-4

  • Molecular Formula : C5H3BrN2O3

  • Molecular Weight : 218.99

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Drug Reference Standards & Impurity Synthesis in India
PA 03 3851016

1-(2-Chloro-3-fluorophenyl)ethan-1-ol

1-(2-Chloro-3-fluorophenyl)ethan-1-ol

  • Catalogue No.:PA 03 3851016

  • CAS :

    1236363-12-4

  • Molecular Formula : C8H8ClFO

  • Molecular Weight : 174.6

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Drug Reference Standards & Impurity Synthesis in India
PA 03 3851017

(S)-1-(2-Chloro-5-fluorophenyl)ethan-1-ol

(S)-1-(2-Chloro-5-fluorophenyl)ethan-1-ol

  • Catalogue No.:PA 03 3851017

  • CAS :

    1932506-72-3

  • Molecular Formula : C8H8ClFO

  • Molecular Weight : 174.6

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Drug Reference Standards & Impurity Synthesis in India
PA 03 3851018

1-(2,4-Dichloro-5-fluorophenyl)ethan-1-ol

1-(2,4-Dichloro-5-fluorophenyl)ethan-1-ol

  • Catalogue No.:PA 03 3851018

  • CAS :

    704-09-6

  • Molecular Formula : C8H7Cl2FO

  • Molecular Weight : 209.04

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Drug Reference Standards & Impurity Synthesis in India
PA 03 3851013

1-(2,4-Dichloro-5-fluorophenyl)ethan-1-one

1-(2,4-Dichloro-5-fluorophenyl)ethan-1-one

  • Catalogue No.:PA 03 3851013

  • CAS :

    704-10-9

  • Molecular Formula : C8H5Cl2FO

  • Molecular Weight : 207.03

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Drug Reference Standards & Impurity Synthesis in India
PA 03 3851019

1-(2,4-Dichloro-3-fluorophenyl)ethan-1-ol

1-(2,4-Dichloro-3-fluorophenyl)ethan-1-ol

  • Catalogue No.:PA 03 3851019

  • CAS :

    NA

  • Molecular Formula : C8H7Cl2FO

  • Molecular Weight : 209.04

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Drug Reference Standards & Impurity Synthesis in India
PA 03 3851020

3,3'-(Oxybis(ethane-1,1-diyl))bis(2,4-dichloro-1-fluorobenzene)

3,3'-(Oxybis(ethane-1,1-diyl))bis(2,4-dichloro-1-fluorobenzene)

  • Catalogue No.:PA 03 3851020

  • CAS :

    NA

  • Molecular Formula : C16H12Cl4F2O

  • Molecular Weight : 400.07

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Drug Reference Standards & Impurity Synthesis in India
PA 03 3851021

(R)-3-(1-(3-Fluorophenyl)ethoxy)pyridin-2-amine

(R)-3-(1-(3-Fluorophenyl)ethoxy)pyridin-2-amine

  • Catalogue No.:PA 03 3851021

  • CAS :

    NA

  • Molecular Formula : C13H13FN2O

  • Molecular Weight : 232.26

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Drug Reference Standards & Impurity Synthesis in India
PA 03 3851022

(R)-3-(1-(2,6-Dichloro-3-fluorophenyl)ethoxy)-2-nitrosopyridine

(R)-3-(1-(2,6-Dichloro-3-fluorophenyl)ethoxy)-2-nitrosopyridine

  • Catalogue No.:PA 03 3851022

  • CAS :

    2509276-77-9

  • Molecular Formula : C13H9Cl2FN2O2

  • Molecular Weight : 315.13

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Drug Reference Standards & Impurity Synthesis in India
PA 03 3851023

(R)-N-(3-(1-(2,6-Dichloro-3-fluorophenyl)ethoxy)pyridin-2-yl)hydroxylamine

(R)-N-(3-(1-(2,6-Dichloro-3-fluorophenyl)ethoxy)pyridin-2-yl)hydroxylamine

  • Catalogue No.:PA 03 3851023

  • CAS :

    2509276-79-1

  • Molecular Formula : C13H11Cl2FN2O2

  • Molecular Weight : 317.14

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Drug Reference Standards & Impurity Synthesis in India
PA 03 3851024

4-Bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine

4-Bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine

  • Catalogue No.:PA 03 3851024

  • CAS :

    NA

  • Molecular Formula : C13H10BrCl2FN2O

  • Molecular Weight : 380.04

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Drug Reference Standards & Impurity Synthesis in India
PA 03 3851025

Di-tert-butyl 4,4'-(1H,1'H-[4,4'-bipyrazole]-1,1'-diyl)bis(piperidine-1-carboxylate)

Di-tert-butyl 4,4'-(1H,1'H-[4,4'-bipyrazole]-1,1'-diyl)bis(piperidine-1-carboxylate)

  • Catalogue No.:PA 03 3851025

  • CAS :

    2107402-00-4

  • Molecular Formula : C26H40N6O4

  • Molecular Weight : 500.64

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Drug Reference Standards & Impurity Synthesis in India
PA 03 3851026

(R)-3-(1-(2-Chloro-3-fluorophenyl)ethoxy)-5-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)pyridin-2-amine

(R)-3-(1-(2-Chloro-3-fluorophenyl)ethoxy)-5-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)pyridin-2-amine

  • Catalogue No.:PA 03 3851026

  • CAS :

    1801651-84-2

  • Molecular Formula : C21H23ClFN5O

  • Molecular Weight : 415.9

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Drug Reference Standards & Impurity Synthesis in India
PA 03 3851027

(R)-3-(1-(2-Chloro-5-fluorophenyl)ethoxy)-5-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)pyridin-2-amine

(R)-3-(1-(2-Chloro-5-fluorophenyl)ethoxy)-5-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)pyridin-2-amine

  • Catalogue No.:PA 03 3851027

  • CAS :

    1558007-80-9

  • Molecular Formula : C21H23ClFN5O

  • Molecular Weight : 415.9

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Drug Reference Standards & Impurity Synthesis in India
PA 03 3851028

5-Bromo-3-(1-(3-bromo-2,6-dichloro-5-fluorophenyl)ethoxy)pyridin-2-amine

5-Bromo-3-(1-(3-bromo-2,6-dichloro-5-fluorophenyl)ethoxy)pyridin-2-amine

  • Catalogue No.:PA 03 3851028

  • CAS :

    NA

  • Molecular Formula : C13H9Br2Cl2FN2O

  • Molecular Weight : 458.93

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Drug Reference Standards & Impurity Synthesis in India
PA 03 3851029

(R)-3-(1-(2-Chloro-3-fluoro-6-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)phenyl)ethoxy)-5-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)pyridin-2-amine

(R)-3-(1-(2-Chloro-3-fluoro-6-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)phenyl)ethoxy)-5-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)pyridin-2-amine

  • Catalogue No.:PA 03 3851029

  • CAS :

    NA

  • Molecular Formula : C29H34ClFN8O

  • Molecular Weight : 565.09

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Drug Reference Standards & Impurity Synthesis in India
PA 03 3851030

(R)-3-(1-(6-Chloro-3-fluoro-2-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)phenyl)ethoxy)-5-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)pyridin-2-amine

(R)-3-(1-(6-Chloro-3-fluoro-2-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)phenyl)ethoxy)-5-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)pyridin-2-amine

  • Catalogue No.:PA 03 3851030

  • CAS :

    NA

  • Molecular Formula : C29H34ClFN8O

  • Molecular Weight : 565.09

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Drug Reference Standards & Impurity Synthesis in India
PA 03 3851031

5,5'-((Methylenebis(piperidine-1,4-diyl))bis(1H-pyrazole-1,4-diyl))bis(3-((R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine)

5,5'-((Methylenebis(piperidine-1,4-diyl))bis(1H-pyrazole-1,4-diyl))bis(3-((R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine)

  • Catalogue No.:PA 03 3851031

  • CAS :

    NA

  • Molecular Formula : C43H44Cl4F2N10O2

  • Molecular Weight : 912.69

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Drug Reference Standards & Impurity Synthesis in India
PA 03 3851032

(R)-3-(1-(2,6-Dichloro-3-fluorophenyl)ethoxy)-5-(1-(1-methylpiperidin-4-yl)-1H-pyrazol-4-yl)pyridin-2-amine

(R)-3-(1-(2,6-Dichloro-3-fluorophenyl)ethoxy)-5-(1-(1-methylpiperidin-4-yl)-1H-pyrazol-4-yl)pyridin-2-amine

  • Catalogue No.:PA 03 3851032

  • CAS :

    NA

  • Molecular Formula : C22H24Cl2FN5O

  • Molecular Weight : 464.37

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PA 03 3851033

(R)-3-(1-(2,6-Dichloro-3-fluorophenyl)ethoxy)-2-nitropyridine

(R)-3-(1-(2,6-Dichloro-3-fluorophenyl)ethoxy)-2-nitropyridine

  • Catalogue No.:PA 03 3851033

  • CAS :

    877397-70-1

  • Molecular Formula : C13H9Cl2FN2O3

  • Molecular Weight : 331.12

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Drug Reference Standards & Impurity Synthesis in India
PA 03 3851034

(R)-5-(1-(2,6-Dichloro-3-fluorophenyl)ethoxy)-2-nitropyridine

(R)-5-(1-(2,6-Dichloro-3-fluorophenyl)ethoxy)-2-nitropyridine

  • Catalogue No.:PA 03 3851034

  • CAS :

    NA

  • Molecular Formula : C13H9Cl2FN2O3

  • Molecular Weight : 331.12

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PA 03 3851035

1,2-Bis(3-((R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-yl)hydrazine

1,2-Bis(3-((R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-yl)hydrazine

  • Catalogue No.:PA 03 3851035

  • CAS :

    NA

  • Molecular Formula : C26H20Cl4F2N4O2

  • Molecular Weight : 600.27

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Drug Reference Standards & Impurity Synthesis in India
PA 03 3851036

1-BOC-4-Piperidone

1-BOC-4-Piperidone

  • Catalogue No.:PA 03 3851036

  • CAS :

    79099-07-3

  • Molecular Formula : C10H17NO3

  • Molecular Weight : 199.25

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PA STI 090165

Crizotinib-D9

Crizotinib-D9

  • Catalogue No.:PA STI 090165

  • CAS :

    1523580-59-7

  • Molecular Formula : C21H13D9Cl2FN5O

  • Molecular Weight : 459.39

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PA 03 3851037

5,6-Dibromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine

5,6-Dibromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine

  • Catalogue No.:PA 03 3851037

  • CAS :

    NA

  • Molecular Formula : C13H9Br2Cl2FN2O

  • Molecular Weight : 458.93

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