Cyclosporin-impurities | Pharmaffiliates

cyclosporin and its Impurities

Ciclosporin, also spelled cyclosporine and cyclosporin, is an immunosuppressant medication and natural product. It is approved by the FDA to treat and prevent graft-versus-host disease in bone marrow transplantation and to prevent rejection of kidney, heart, and liver transplants.. Reference standards of Cyclosporin API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below

Displaying 39 results for cyclosporin Impurities
PA 03 84000

Cyclosporin - API

Cyclosporin


  • Catalogue No.:PA 03 84000

  • CAS :

    59865-13-3

  • Molecular Formula : C62H111N11O12

  • Molecular Weight : 1202.61

PA 03 84010

Cyclosporin - Impurity B

1,11-Anhydro[L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-N-methyl-L-[(1S,2R)-1-hydroxy-2-methylhexyl]glycl-L-2-aminobutanoyl-N-methylglycyl-N-methyl-L-leucylL-valyl-N-methyl-L-leucine] ([6-L-[(1S,2R)-1-hydroxy-2-methylhexyl]glycine]ciclosporin A)


  • Catalogue No.:PA 03 84010

  • CAS :

    59865-15-5

  • Molecular Formula : C62H113N11O12

  • Molecular Weight : 1204.63

PA 03 84020

Cyclosporin B

Cyclosporin B


  • Catalogue No.:PA 03 84020

  • CAS :

    63775-95-1

  • Molecular Formula : C61H109N11O12

  • Molecular Weight : 1188.58

PA 03 84030

Cyclosporin C

Cyclosporin C


  • Catalogue No.:PA 03 84030

  • CAS :

    59787-61-0

  • Molecular Formula : C62H111N11O13

  • Molecular Weight : 1218.64

PA 03 84040

Cyclosporin D

Cyclosporin D


  • Catalogue No.:PA 03 84040

  • CAS :

    63775-96-2

  • Molecular Formula : C63H113N11O12

  • Molecular Weight : 1216.64

PA 03 84080

Cyclosporin H

Cyclosporin H


  • Catalogue No.:PA 03 84080

  • CAS :

    83602-39-5

  • Molecular Formula : C62H111N11O12

  • Molecular Weight : 1202.63

PA 03 84510

Cyclosporin - Impurity C

Iso Cyclosporin A


  • Catalogue No.:PA 03 84510

  • CAS :

    59865-16-6

  • Molecular Formula : C62H111N11O12

  • Molecular Weight : 1202.61

PA 03 84520

Cyclosporin G

Cyclosporin G


  • Catalogue No.:PA 03 84520

  • CAS :

    74436-00-3

  • Molecular Formula : C63H113N11O12

  • Molecular Weight : 1216.64

PA 03 84530

Cyclosporine Resolution Mixture

Cyclosporine Resolution Mixture


  • Catalogue No.:PA 03 84530

  • CAS :

    NA

  • Molecular Formula : C61H109N11O12

  • Molecular Weight : 1188.58

PA 03 84540

Acetoxy Cyclosporin A Acetate

Acetoxy Cyclosporin A Acetate


  • Catalogue No.:PA 03 84540

  • CAS :

    138957-23-0

  • Molecular Formula : C66H115N11O15

  • Molecular Weight : 1302.7

PA 03 84550

Iso Cyclosporin H Trifluoroacetic Acid Salt

Iso Cyclosporin H Trifluoroacetic Acid Salt


  • Catalogue No.:PA 03 84550

  • CAS :

    NA

  • Molecular Formula : C62H111N11O12•x(C2HF3O2)

  • Molecular Weight : 1202.61 + x(114.02)

PA STI 023700

Cyclosporin A-d4 Acetate (Major)

Cyclosporin A-d4 Acetate (Major)


  • Catalogue No.:PA STI 023700

  • CAS :

    NA

  • Molecular Formula : C64H109D4N11O13

  • Molecular Weight : 1248.67

PA STI 023710

Cyclosporin A-13C2,d4 Acetate

Cyclosporin A-13C2,d4 Acetate


  • Catalogue No.:PA STI 023710

  • CAS :

    NA

  • Molecular Formula : C6213C2H109D4N11O13

  • Molecular Weight : 1250.65

PA STI 023720

Cyclosporin A-13C2,d4 (Major)

Cyclosporin A-13C2,d4 (Major)


  • Catalogue No.:PA STI 023720

  • CAS :

    NA

  • Molecular Formula : C6013C2H107D4N11O12

  • Molecular Weight : 1208.62

PA STI 023730

Cyclosporin A-d4 (Major)

Cyclosporin A-d4 (Major)


  • Catalogue No.:PA STI 023730

  • CAS :

    NA

  • Molecular Formula : C62H107D4N11O12

  • Molecular Weight : 1206.64

PA STI 023740

Cyclosporin B-d4

Cyclosporin B-d4


  • Catalogue No.:PA STI 023740

  • CAS :

    NA

  • Molecular Formula : C61H105D4N11O12

  • Molecular Weight : 1192.58

PA STI 023750

Cyclosporin C-d4

Cyclosporin C-d4


  • Catalogue No.:PA STI 023750

  • CAS :

    NA

  • Molecular Formula : C62H107D4N11O13

  • Molecular Weight : 1222.64

PA STI 023760

Cyclosporin D-d4

Cyclosporin D-d4


  • Catalogue No.:PA STI 023760

  • CAS :

    NA

  • Molecular Formula : C63H109D4N11O12

  • Molecular Weight : 1220.66

PA STI 023770

Cyclosporin H-d4

Cyclosporin H-d4


  • Catalogue No.:PA STI 023770

  • CAS :

    NA

  • Molecular Formula : C62H107D4N11O12

  • Molecular Weight : 1206.64

PA 03 84560

Cyclosporin E

Cyclosporin E


  • Catalogue No.:PA 03 84560

  • CAS :

    63798-73-2

  • Molecular Formula : C61H109N11O12

  • Molecular Weight : 1188.61

PA 03 84570

Cyclosporin L

Cyclosporin L


  • Catalogue No.:PA 03 84570

  • CAS :

    108027-39-0

  • Molecular Formula : C61H109N11O12

  • Molecular Weight : 1188.61

PA 03 84580

Iso Cyclosporine H

Iso Cyclosporine H


  • Catalogue No.:PA 03 84580

  • CAS :

    83602-43-1

  • Molecular Formula : C62H111N11O12

  • Molecular Weight : 1202.64

PA 03 84590

(3S,6S,9S,12R,15S,18S,21S,24S,27R,30S,33S)-27-((2-(Dimethylamino)ethyl)thio)-30-ethyl-33-((1R,2R,E)-1-hydroxy-2-methylhex-4-en-1-yl)-24-(2-hydroxy-2-methylpropyl)-6,9,18-triisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29,32-undecaone

(3S,6S,9S,12R,15S,18S,21S,24S,27R,30S,33S)-27-((2-(Dimethylamino)ethyl)thio)-30-ethyl-33-((1R,2R,E)-1-hydroxy-2-methylhex-4-en-1-yl)-24-(2-hydroxy-2-methylpropyl)-6,9,18-triisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29,32-undecaone


  • Catalogue No.:PA 03 84590

  • CAS :

    210759-10-7

  • Molecular Formula : C66H120N12O13S

  • Molecular Weight : 1321.82

PAI 03 038010

(1R,2R,E)-1-((2R,5R,14S,17R,20S,23S,26R,29S,32R)-8-ethyl-14,20,29,32-Tetraisobutyl-2,17-diisopropyl-1,4,10,13,19,23,26,28,31-nonamethyl-3,9,12,15,18,21,24,27,30,35-decaoxo-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclopentatriacontan-5-yl)-2-methylhex-4-en-1-yl Acetate

(1R,2R,E)-1-((2R,5R,14S,17R,20S,23S,26R,29S,32R)-8-ethyl-14,20,29,32-Tetraisobutyl-2,17-diisopropyl-1,4,10,13,19,23,26,28,31-nonamethyl-3,9,12,15,18,21,24,27,30,35-decaoxo-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclopentatriacontan-5-yl)-2-methylhex-4-en-1-yl Acetate


  • Catalogue No.:PAI 03 038010

  • CAS :

    NA

  • Molecular Formula : C66H119N11O12

  • Molecular Weight : 1258.74

PAI 03 038020

Cyclosporin A Acetate

Cyclosporin A Acetate


  • Catalogue No.:PAI 03 038020

  • CAS :

    83602-41-9

  • Molecular Formula : C64H113N11O13

  • Molecular Weight : 1244.67

PAI 03 038030

(1R,2R,E)-6-Bromo-1-((2S,5S,11S,14S,17S,20S,23R,26S,29S,32S)-5-ethyl-11,17,26,29-tetraisobutyl-14,32-diisopropyl-1,7,10,16,20,23,25,28,31-nonamethyl-3,6,9,12,15,18,21,24,27,30,33-undecaoxo-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2-yl)-2-methylhex-4-en-1-yl Acetate

(1R,2R,E)-6-Bromo-1-((2S,5S,11S,14S,17S,20S,23R,26S,29S,32S)-5-ethyl-11,17,26,29-tetraisobutyl-14,32-diisopropyl-1,7,10,16,20,23,25,28,31-nonamethyl-3,6,9,12,15,18,21,24,27,30,33-undecaoxo-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2-yl)-2-methylhex-4-en-1-yl Acetate


  • Catalogue No.:PAI 03 038030

  • CAS :

    138957-22-9

  • Molecular Formula : C64H112BrN11O13

  • Molecular Weight : 1323.57

PA 03 0841000

Abu 5-Cyclosporin

Abu 5-Cyclosporin


  • Catalogue No.:PA 03 0841000

  • CAS :

    437611-17-1

  • Molecular Formula : C61H109N11O12

  • Molecular Weight : 1188.61

PA 03 0841001

(3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-15,30-Diethyl-33-((1R,2R,E)-1-hydroxy-2-methylhex-4-en-1-yl)-6,9,18,24-tetraisobutyl-3,21-diisopropyl-1,4,7,10,12,19,25,28-octamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29,32-undecaone

(3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-15,30-Diethyl-33-((1R,2R,E)-1-hydroxy-2-methylhex-4-en-1-yl)-6,9,18,24-tetraisobutyl-3,21-diisopropyl-1,4,7,10,12,19,25,28-octamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29,32-undecaone


  • Catalogue No.:PA 03 0841001

  • CAS :

    NA

  • Molecular Formula : C63H113N11O12

  • Molecular Weight : 1216.66

PA 03 0841003

Sodium 4-hydroxy-4-methyl-2-(methylamino)pentanoate

Sodium 4-hydroxy-4-methyl-2-(methylamino)pentanoate


  • Catalogue No.:PA 03 0841003

  • CAS :

    NA

  • Molecular Formula : C7H14NNaO3

  • Molecular Weight : 183.18

PA 03 0840070

Cyclosporin - Impurity G

Ciclosporin D


  • Catalogue No.:PA 03 0840070

  • CAS :

    63775-96-2

  • Molecular Formula : NA

  • Molecular Weight : NA

PA 03 0840050

Cyclosporin - Impurity E

Ciclosporin V


  • Catalogue No.:PA 03 0840050

  • CAS :

    108027-46-9

  • Molecular Formula : NA

  • Molecular Weight : NA

PA 03 0841004

Cyclosporin A, 3-(4-hydroxy-N-methyl-L-leucine)

Cyclosporin A, 3-(4-hydroxy-N-methyl-L-leucine)


  • Catalogue No.:PA 03 0841004

  • CAS :

    89270-25-7

  • Molecular Formula : C62H111N11O13

  • Molecular Weight : 1218.63

PA 03 0840060

Cyclosporin - Impurity F

Abu10-Ciclosporin A


  • Catalogue No.:PA 03 0840060

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

PA 03 0841005

Cyclosporin Q

Cyclosporin Q


  • Catalogue No.:PA 03 0841005

  • CAS :

    108027-42-5

  • Molecular Formula : C60H107N11O12

  • Molecular Weight : 1174.58

PA 03 0841006

Dihydrocyclosporin H

Dihydrocyclosporin H


  • Catalogue No.:PA 03 0841006

  • CAS :

    83602-88-4

  • Molecular Formula : C62H113N11O12

  • Molecular Weight : 1204.65

PA 03 0841007

Cyclosporin AM 1

Cyclosporin AM 1


  • Catalogue No.:PA 03 0841007

  • CAS :

    89270-28-0

  • Molecular Formula : C62H111N11O13

  • Molecular Weight : 1218.63

PA 03 0840040

Cyclosporin - Impurity D

Ciclosporin U


  • Catalogue No.:PA 03 0840040

  • CAS :

    108027-45-8

  • Molecular Formula : C61H109N11O12

  • Molecular Weight : 1188.61

PA 03 0841008

Cyclosporin T

Cyclosporin T


  • Catalogue No.:PA 03 0841008

  • CAS :

    108027-44-7

  • Molecular Formula : C61H109N11O12

  • Molecular Weight : 1188.61

PA 03 0841009

(4S,5R)-5-((R,E)-Hex-4-en-2-yl)-3-methyl-2-oxo-N-((4S,7S,10R,13S,16S,19S,22S,28S)-4,7,16,22-tetraisobutyl-19-isopropyl-5,8,10,13,17,23,26-heptamethyl-3,6,9,12,15,18,21,24,27-nonaoxo-2,5,8,11,14,17,20,23,26-nonaazatriacontan-28-yl)oxazolidine-4-carboxamide

(4S,5R)-5-((R,E)-Hex-4-en-2-yl)-3-methyl-2-oxo-N-((4S,7S,10R,13S,16S,19S,22S,28S)-4,7,16,22-tetraisobutyl-19-isopropyl-5,8,10,13,17,23,26-heptamethyl-3,6,9,12,15,18,21,24,27-nonaoxo-2,5,8,11,14,17,20,23,26-nonaazatriacontan-28-yl)oxazolidine-4-carboxamide


  • Catalogue No.:PA 03 0841009

  • CAS :

    1907654-63-0

  • Molecular Formula : C58H103N11O12

  • Molecular Weight : 1146.53