dabrafenib and its Impurities

Dabrafenib is a reversible ATP-competitive kinase inhibitor and targets the MAPK pathway. It is used alone or in combination with another medication to treat a type of skin cancer.. Reference standards of Dabrafenib API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below

Displaying 43 results for dabrafenib Impurities
PA 31 06000

Dabrafenib

Dabrafenib

  • Catalogue No.:PA 31 06000

  • CAS :

    1195765-45-7

  • Molecular Formula : C23H20F3N5O2S2

  • Molecular Weight : 519.56

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PA 31 06510

3-Bromo-2-fluorobenzoic Acid

3-Bromo-2-fluorobenzoic Acid

  • Catalogue No.:PA 31 06510

  • CAS :

    161957-56-8

  • Molecular Formula : C7H4BrFO2

  • Molecular Weight : 219.01

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PA 31 06520

Dabrafenib Mesylate

Dabrafenib Mesylate

  • Catalogue No.:PA 31 06520

  • CAS :

    1195768-06-9

  • Molecular Formula : C24H24F3N5O5S3

  • Molecular Weight : 615.67

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PA 31 06530

2,6-Difluorobenzenesulfonyl Chloride

2,6-Difluorobenzenesulfonyl Chloride

  • Catalogue No.:PA 31 06530

  • CAS :

    60230-36-6

  • Molecular Formula : C6H3ClF2O2S

  • Molecular Weight : 212.6

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PA 31 06540

2,2-Dimethylthiopropionamide

2,2-Dimethylthiopropionamide

  • Catalogue No.:PA 31 06540

  • CAS :

    630-22-8

  • Molecular Formula : C5H11NS

  • Molecular Weight : 117.21

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PA 31 0061000

2-Amino-N-(3-(5-(2-aminopyrimidin-4-yl)-2-(tert-butyl)thiazol-4-yl)-2-fluorophenyl)-6-fluorobenzenesulfonamide

2-Amino-N-(3-(5-(2-aminopyrimidin-4-yl)-2-(tert-butyl)thiazol-4-yl)-2-fluorophenyl)-6-fluorobenzenesulfonamide

  • Catalogue No.:PA 31 0061000

  • CAS :

    2017554-98-0

  • Molecular Formula : C23H22F2N6O2S2

  • Molecular Weight : 516.59

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PA 31 0061001

Carboxy Dabrafenib

Carboxy Dabrafenib

  • Catalogue No.:PA 31 0061001

  • CAS :

    1195873-54-1

  • Molecular Formula : C23H18F3N5O4S2

  • Molecular Weight : 549.54

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PA 31 0061002

Hydroxy Dabrafenib

Hydroxy Dabrafenib

  • Catalogue No.:PA 31 0061002

  • CAS :

    1195767-77-1

  • Molecular Formula : C23H20F3N5O3S2

  • Molecular Weight : 535.56

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PA 31 0061003

Desmethyl Dabrafenib

Desmethyl Dabrafenib

  • Catalogue No.:PA 31 0061003

  • CAS :

    1195765-47-9

  • Molecular Formula : C22H18F3N5O2S2

  • Molecular Weight : 505.53

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PA STI 089392

Dabrafenib-d9

Dabrafenib-d9

  • Catalogue No.:PA STI 089392

  • CAS :

    1423119-98-5

  • Molecular Formula : C23H11D9F3N5O2S2

  • Molecular Weight : 528.62

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PA 31 0061004

2,4-Difluorobenzenesulfonyl Chloride

2,4-Difluorobenzenesulfonyl Chloride

  • Catalogue No.:PA 31 0061004

  • CAS :

    13918-92-8

  • Molecular Formula : C6H3ClF2O2S

  • Molecular Weight : 212.59

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PA 31 0061005

4-Bromo-2-fluorobenzenesulfonyl Chloride

4-Bromo-2-fluorobenzenesulfonyl Chloride

  • Catalogue No.:PA 31 0061005

  • CAS :

    216159-03-4

  • Molecular Formula : C6H3BrClFO2S

  • Molecular Weight : 273.5

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PA 31 0061006

2,4,6-Trifluorobenzene-1-sulfonyl Chloride

2,4,6-Trifluorobenzene-1-sulfonyl Chloride

  • Catalogue No.:PA 31 0061006

  • CAS :

    220239-64-5

  • Molecular Formula : C6H2ClF3O2S

  • Molecular Weight : 230.59

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PA 31 0061007

2-Fluoro-6-methoxybenzenesulphonyl Chloride

2-Fluoro-6-methoxybenzenesulphonyl Chloride

  • Catalogue No.:PA 31 0061007

  • CAS :

    1176126-31-0

  • Molecular Formula : C7H6ClFO3S

  • Molecular Weight : 224.63

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PA 31 0061008

Methyl 3-amino-4-fluorobenzoate

Methyl 3-amino-4-fluorobenzoate

  • Catalogue No.:PA 31 0061008

  • CAS :

    369-26-6

  • Molecular Formula : C8H8FNO2

  • Molecular Weight : 169.16

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PA 31 0061009

Methyl 3-amino-5-fluorobenzoate

Methyl 3-amino-5-fluorobenzoate

  • Catalogue No.:PA 31 0061009

  • CAS :

    884497-46-5

  • Molecular Formula : C8H8FNO2

  • Molecular Weight : 169.16

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PA 31 0061010

Methyl 5-amino-2-fluorobenzoate

Methyl 5-amino-2-fluorobenzoate

  • Catalogue No.:PA 31 0061010

  • CAS :

    56741-34-5

  • Molecular Formula : C8H8FNO2

  • Molecular Weight : 169.16

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PA 31 0061011

3-Amino-2-fluorobenzoic Acid

3-Amino-2-fluorobenzoic Acid

  • Catalogue No.:PA 31 0061011

  • CAS :

    914223-43-1

  • Molecular Formula : C7H6FNO2

  • Molecular Weight : 155.13

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PA 31 0061012

N-(3-(5-(2-Aminopyrimidin-4-yl)-2-(tert-butyl)thiazol-4-yl)-2-fluorophenyl)-2-fluoro-6-methoxybenzenesulfonamide

N-(3-(5-(2-Aminopyrimidin-4-yl)-2-(tert-butyl)thiazol-4-yl)-2-fluorophenyl)-2-fluoro-6-methoxybenzenesulfonamide

  • Catalogue No.:PA 31 0061012

  • CAS :

    NA

  • Molecular Formula : C24H23F2N5O3S2

  • Molecular Weight : 531.6

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PA 31 0061013

2-Fluoro-6-nitrobenzenesulfonyl Chloride

2-Fluoro-6-nitrobenzenesulfonyl Chloride

  • Catalogue No.:PA 31 0061013

  • CAS :

    887266-98-0

  • Molecular Formula : C6H3ClFNO4S

  • Molecular Weight : 239.6

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PA 31 0061014

Methyl 3-amino-2-methoxybenzoate

Methyl 3-amino-2-methoxybenzoate

  • Catalogue No.:PA 31 0061014

  • CAS :

    5129-25-9

  • Molecular Formula : C9H11NO3

  • Molecular Weight : 181.19

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PA 31 0061015

N-(3-(5-(2-Aminopyrimidin-4-yl)-2-(tert-butyl)thiazol-4-yl)phenyl)-2,6-difluorobenzenesulfonamide

N-(3-(5-(2-Aminopyrimidin-4-yl)-2-(tert-butyl)thiazol-4-yl)phenyl)-2,6-difluorobenzenesulfonamide

  • Catalogue No.:PA 31 0061015

  • CAS :

    NA

  • Molecular Formula : C23H21F2N5O2S2

  • Molecular Weight : 501.57

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PA 31 0061016

N-(3-(2-(Tert-butyl)-5-(2-(dimethylamino)pyrimidin-4-yl)thiazol-4-yl)-2-fluorophenyl)-2,6-difluorobenzenesulfonamide

N-(3-(2-(Tert-butyl)-5-(2-(dimethylamino)pyrimidin-4-yl)thiazol-4-yl)-2-fluorophenyl)-2,6-difluorobenzenesulfonamide

  • Catalogue No.:PA 31 0061016

  • CAS :

    NA

  • Molecular Formula : C25H24F3N5O2S2

  • Molecular Weight : 547.62

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PA 31 0061017

M30-Dabrafenib

M30-Dabrafenib

  • Catalogue No.:PA 31 0061017

  • CAS :

    1613724-38-1

  • Molecular Formula : C22H16F3N5O5S2

  • Molecular Weight : 551.52

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PA 31 0061018

M31-Dabrafenib

M31-Dabrafenib

  • Catalogue No.:PA 31 0061018

  • CAS :

    1613724-51-8

  • Molecular Formula : C22H16F3N5O2S2

  • Molecular Weight : 503.52

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PA 31 0061019

Dabrafenib Glucuronide

Dabrafenib Glucuronide

  • Catalogue No.:PA 31 0061019

  • CAS :

    2147682-66-2

  • Molecular Formula : C28H24F3N5O9S2

  • Molecular Weight : 695.64

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PA 31 0061020

1-(2-chloropyrimidin-4-yl)-2-(3-((2,6-difluorophenyl)sulfonamido)-2-fluorophenyl)-2-oxoethyl 2,2-dimethylpropanimidothioate

1-(2-chloropyrimidin-4-yl)-2-(3-((2,6-difluorophenyl)sulfonamido)-2-fluorophenyl)-2-oxoethyl 2,2-dimethylpropanimidothioate

  • Catalogue No.:PA 31 0061020

  • CAS :

    NA

  • Molecular Formula : C23H20ClF3N4O3S2

  • Molecular Weight : 557

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PA 31 0061021

Methyl 3-((2,6-difluorophenyl)sulfonamido)-2-fluorobenzoate

Methyl 3-((2,6-difluorophenyl)sulfonamido)-2-fluorobenzoate

  • Catalogue No.:PA 31 0061021

  • CAS :

    1195768-19-4

  • Molecular Formula : C14H10F3NO4S

  • Molecular Weight : 345.29

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PA 31 0061022

N-(3-(2-(tert-Butyl)-5-(2-hydroxypyrimidin-4-yl)thiazol-4-yl)-2-fluorophenyl)-2,6-difluorobenzenesulfonamide

N-(3-(2-(tert-Butyl)-5-(2-hydroxypyrimidin-4-yl)thiazol-4-yl)-2-fluorophenyl)-2,6-difluorobenzenesulfonamide

  • Catalogue No.:PA 31 0061022

  • CAS :

    NA

  • Molecular Formula : C23H19F3N4O3S2

  • Molecular Weight : 520.55

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PA 31 0061023

2,6-Difluoro-N-(2-fluoro-3-(2-(2-hydroxypyrimidin-4-yl)acetyl)phenyl)benzenesulfonamide

2,6-Difluoro-N-(2-fluoro-3-(2-(2-hydroxypyrimidin-4-yl)acetyl)phenyl)benzenesulfonamide

  • Catalogue No.:PA 31 0061023

  • CAS :

    NA

  • Molecular Formula : C18H12F3N3O4S

  • Molecular Weight : 423.37

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PA 31 0061024

2,6-Difluorobenzenesulfonyl Fluoride

2,6-Difluorobenzenesulfonyl Fluoride

  • Catalogue No.:PA 31 0061024

  • CAS :

    447460-43-7

  • Molecular Formula : C6H3F3O2S

  • Molecular Weight : 196.14

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PA 31 0061025

N-(3-(2-(tert-Butyl)-4-hydroxy-5-(2-hydroxypyrimidin-4-yl)-4,5-dihydrothiazol-4-yl)-2-fluorophenyl)-2,6-difluorobenzenesulfonamide

N-(3-(2-(tert-Butyl)-4-hydroxy-5-(2-hydroxypyrimidin-4-yl)-4,5-dihydrothiazol-4-yl)-2-fluorophenyl)-2,6-difluorobenzenesulfonamide

  • Catalogue No.:PA 31 0061025

  • CAS :

    NA

  • Molecular Formula : C23H21F3N4O4S2

  • Molecular Weight : 538.56

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PA 31 0061026

N-(3-(2-(Tert-butyl)-5-(2-chloropyrimidin-4-yl)thiazol-4-yl)-2-fluorophenyl)-2,6-difluorobenzenesulfonamide

N-(3-(2-(Tert-butyl)-5-(2-chloropyrimidin-4-yl)thiazol-4-yl)-2-fluorophenyl)-2,6-difluorobenzenesulfonamide

  • Catalogue No.:PA 31 0061026

  • CAS :

    1195768-23-0

  • Molecular Formula : C23H18ClF3N4O2S2

  • Molecular Weight : 538.99

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PA 31 0061027

Methyl 2-fluoro-3-((2-fluoro-6-hydroxyphenyl)sulfonamido)benzoate

Methyl 2-fluoro-3-((2-fluoro-6-hydroxyphenyl)sulfonamido)benzoate

  • Catalogue No.:PA 31 0061027

  • CAS :

    NA

  • Molecular Formula : C14H11F2NO5S

  • Molecular Weight : 343.3

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PA 31 0061028

Dabrafenib Amine Impurity

Dabrafenib Amine Impurity

  • Catalogue No.:PA 31 0061028

  • CAS :

    1195769-01-7

  • Molecular Formula : C17H18FN5S

  • Molecular Weight : 343.42

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PA 31 0061029

N-(3-(2-(2-Aminopyrimidin-4-yl)acetyl)-2-fluorophenyl)-2,6-difluorobenzenesulfonamide

N-(3-(2-(2-Aminopyrimidin-4-yl)acetyl)-2-fluorophenyl)-2,6-difluorobenzenesulfonamide

  • Catalogue No.:PA 31 0061029

  • CAS :

    NA

  • Molecular Formula : C18H13F3N4O3S

  • Molecular Weight : 422.38

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PA 31 0061030

Dabrafenib Diamine Sulfonamide Impurity

Dabrafenib Diamine Sulfonamide Impurity

  • Catalogue No.:PA 31 0061030

  • CAS :

    NA

  • Molecular Formula : C23H22F2N6O2S2

  • Molecular Weight : 516.59

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PA 31 0061031

5-(2-Aminopyrimidin-4-yl)-2-(tert-butyl)-4-(3-((2,6-difluorophenyl)sulfonamido)-2-fluorophenyl)thiazole 3-oxide

5-(2-Aminopyrimidin-4-yl)-2-(tert-butyl)-4-(3-((2,6-difluorophenyl)sulfonamido)-2-fluorophenyl)thiazole 3-oxide

  • Catalogue No.:PA 31 0061031

  • CAS :

    NA

  • Molecular Formula : C23H20F3N5O3S2

  • Molecular Weight : 535.56

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PA 31 0061032

2-Amino-4-(2-(tert-butyl)-4-(3-((2,6-difluorophenyl)sulfonamido)-2-fluorophenyl)thiazol-5-yl)pyrimidine 1-oxide

2-Amino-4-(2-(tert-butyl)-4-(3-((2,6-difluorophenyl)sulfonamido)-2-fluorophenyl)thiazol-5-yl)pyrimidine 1-oxide

  • Catalogue No.:PA 31 0061032

  • CAS :

    NA

  • Molecular Formula : C23H20F3N5O3S2

  • Molecular Weight : 535.56

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PA 31 0061033

Dabrafenib Methoxy Impurity

Dabrafenib Methoxy Impurity

  • Catalogue No.:PA 31 0061033

  • CAS :

    1907654-22-1

  • Molecular Formula : C24H21F3N4O3S2

  • Molecular Weight : 534.57

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PA 31 0061034

Dabrafenib des-(tert-butyl)thiazol chloro impurity

Dabrafenib des-(tert-butyl)thiazol chloro impurity

  • Catalogue No.:PA 31 0061034

  • CAS :

    1195768-20-7

  • Molecular Formula : C18H11ClF3N3O3S

  • Molecular Weight : 441.81

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PA 31 0061035

1-(3-Amino-2-fluorophenyl)-2-(2-chloropyrimidin-4-yl)ethan-1-one

1-(3-Amino-2-fluorophenyl)-2-(2-chloropyrimidin-4-yl)ethan-1-one

  • Catalogue No.:PA 31 0061035

  • CAS :

    NA

  • Molecular Formula : C12H9ClFN3O

  • Molecular Weight : 265.67

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PA 31 0061036

N-(3-(2-(2-Chloropyrimidin-4-yl)acetyl)-2-fluorophenyl)-N-((2,6-difluorophenyl)sulfonyl)-2,6-difluorobenzenesulfonamide

N-(3-(2-(2-Chloropyrimidin-4-yl)acetyl)-2-fluorophenyl)-N-((2,6-difluorophenyl)sulfonyl)-2,6-difluorobenzenesulfonamide

  • Catalogue No.:PA 31 0061036

  • CAS :

    NA

  • Molecular Formula : C24H13ClF5N3O5S2

  • Molecular Weight : 617.95

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CPHI INDIA- 28, 30 November