Dapagliflozin, sold under the brand name Farxiga. It is used along with diet and exercise to improve glycemic control in adults with type 2 diabetes. It is of the gliflozin class.. Reference standards of Dapagliflozin API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below
Dapagliflozin
Catalogue No.:PA 04 93000
CAS :
Molecular Formula : C21H25ClO6
Molecular Weight : 408.87
4-Bromo-1-chloro-2-(4-ethoxybenzyl)benzene
Catalogue No.:PA 04 93510
Molecular Formula : C15H14BrClO
Molecular Weight : 325.63
1α-Methyl Dapagliflozin
Catalogue No.:PA 04 93520
Molecular Formula : C22H27ClO7
Molecular Weight : 438.9
Dapagliflozin Tetraacetate
Catalogue No.:PA 04 93530
Molecular Formula : C29H33ClO10
Molecular Weight : 577.02
4-Dechloro-4-bromo Dapagliflozin (S)-(+)-1,2-Propanediol Monohydrate
Catalogue No.:PA 04 93540
Molecular Formula : C24H35BrO9
Molecular Weight : 547.43
Dapagliflozin Hydroxy
Catalogue No.:PA 04 93550
Molecular Formula : C21H25ClO7
Molecular Weight : 424.87
Dapagliflozin α-Isomer
Catalogue No.:PA 04 93560
Dapagliflozin Sugar Dimer
Catalogue No.:PA 04 93570
Molecular Formula : C42H48Cl2O12
Molecular Weight : 815.73
4-Deschloro-4-bromo Dapagliflozin
Catalogue No.:PA 04 93580
Molecular Formula : C21H25BrO6
Molecular Weight : 453.32
Dapagliflozin Allose Isomer
Catalogue No.:PA 04 93600
Dapagliflozin Manno Isomer
Catalogue No.:PA 04 93610
Dapagliflozin Galacto Isomer
Catalogue No.:PA 04 93620
(2-Chloro-5-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)phenyl)(4-ethoxyphenyl)methanone
Catalogue No.:PA 04 93630
Molecular Formula : C21H23ClO7
Molecular Weight : 422.86
(2S,3R,4R,5S,6R)-2-(4-Chloro-3-((4-ethoxyphenyl)(hydroxy)methyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
Catalogue No.:PA 04 93640
Dapagliflozin Open Ring Impurity
Catalogue No.:PA 04 93650
Molecular Formula : C21H27ClO7
Molecular Weight : 426.89
(2R,3S,4S,5R,6S)-2-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
Catalogue No.:PA 04 93660
rel-(2S,3R,4R,5S,6R)-2-(3-(4-Ethoxybenzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
Catalogue No.:PA 04 93670
Molecular Formula : C21H26O6
Molecular Weight : 374.43
(3R,4R)-2-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-5-((R)-1,2-dihydroxyethyl)tetrahydrofuran-3,4-diol
Catalogue No.:PA 04 93680
(1S,2S,3R,4R,5R)-1-(4-Chloro-3-(4-ethoxybenzyl)phenyl)hexane-1,2,3,4,5,6-hexaol
Catalogue No.:PA 04 93690
(2S,3R,4R,5S,6R)-2-(4-Chloro-3-(2-ethoxybenzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
Catalogue No.:PA 04 93710
1-Chloro-2-(4-ethoxybenzyl)benzene
Catalogue No.:PA 04 93720
Molecular Formula : C15H15ClO
Molecular Weight : 246.73
4,4'-Dichloro-3,3'-bis(4-ethoxybenzyl)biphenyl
Catalogue No.:PA 04 93730
Molecular Formula : C30H28Cl2O2
Molecular Weight : 491.45
MonoAcetyl Dapagliflozin
Catalogue No.:PA 04 93740
Molecular Formula : C23H27ClO7
Molecular Weight : 450.91
(2S,3R,4R,5S,6R)-2-(4-Chloro-3-((4-ethoxyphenyl)(hydroperoxy)methyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
Catalogue No.:PA 04 93750
Molecular Formula : C21H25ClO8
Molecular Weight : 440.87
2,5-Dibromobenzoic Acid
Catalogue No.:PA 04 93760
Molecular Formula : C7H4Br2O2
Molecular Weight : 279.91
Δ-D-Mannonolactone
Catalogue No.:PA 04 93770
Molecular Formula : C6H10O6
Molecular Weight : 178.14
(2R,3R,4S,5R,6R)-6-(Acetoxymethyl)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl Tetraacetate
Catalogue No.:PA 04 93780
Molecular Formula : C31H35ClO12
Molecular Weight : 635.06
(2S,3R,4S,5R,6R)-6-(Acetoxymethyl)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-2-(((2S,3R,4S,5R,6S)-3,4,5-triacetoxy-6-(4-chloro-3-(4-ethoxybenzyl)phenyl)-6-methoxytetrahydro-2H-pyran-2-yl)methoxy)tetrahydro-2H-pyran-3,4,5-triyl Triacetate
Catalogue No.:PA 04 93790
Molecular Formula : C57H64Cl2O20
Molecular Weight : 1140.01
(2S,3R,4S,5R,6R)-6-(Acetoxymethyl)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-2-(((2S,3R,4S,5R)-3,4,5-triacetoxy-6-oxotetrahydro-2H-pyran-2-yl)methoxy)tetrahydro-2H-pyran-3,4,5-triyl Triacetate
Catalogue No.:PA 04 93800
Molecular Formula : C41H47ClO19
Molecular Weight : 879.25
4,4'-Dichloro-3-(3-ethoxybenzyl)-3'-(4-ethoxybenzyl)-1,1'-biphenyl
Catalogue No.:PA 04 93810
Dapagliflozin Dimer
Catalogue No.:PA 04 93820
(3R,4S,5S,6R)-6-((((2S,3R,4S,5S,6R)-2-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)methyl)-3,4,5-trihydroxytetrahydro-2H-pyran-2-one
Catalogue No.:PA 04 93830
Molecular Formula : C27H33ClO12
Molecular Weight : 585
(2S,3R,4R,5S,6R)-2-(3-Bromo-2-(4-ethoxybenzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
Catalogue No.:PA 04 93840
(2S,3S,4S,5S,6R)-2-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-6-(hydroxymethyl)-2-methoxytetrahydro-2H-pyran-3,4,5-triol
Catalogue No.:PA 04 93850
(2S,3R,4R)-1-(4-Chloro-3-(4-ethoxybenzyl)phenyl)hexane-1,2,3,4,5,6-hexaol
Catalogue No.:PA 04 93860
(2S,3R,4S,5S,6R)-2-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-2-(((2R,3S,4R,5R,6R)-6-(4-chloro-3-(4-ethoxybenzyl)phenyl)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)methoxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
Catalogue No.:PA 04 93870
Dapagliflozin-D5
Catalogue No.:PA STI 024280
Molecular Formula : C21H20D5ClO6
Molecular Weight : 413.90
Dapagliflozin-d4
Catalogue No.:PA STI 024281
Molecular Formula : C21H21D4ClO6
Molecular Weight : 412.90
(1S)-1,4-Anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-D-glucitol
Catalogue No.:PA 04 93880
Molecular Weight : 408.88
5-Bromo-2-chlorobenzoic Acid
Catalogue No.:PA 04 93910
Molecular Formula : C7H4BrClO2
Molecular Weight : 235.46
(2S,3S,4S,5R,6R)-6-(Acetoxymethyl)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-5-hydroxytetrahydro-2H-pyran-3,4-diyl Diacetate
Catalogue No.:PA 04 93920
Molecular Formula : C27H31ClO9
Molecular Weight : 534.99
(4-Chloro-3-(4-ethoxybenzyl)phenyl)trimethylsilane
Catalogue No.:PA 04 93930
Molecular Formula : C18H23ClOSi
Molecular Weight : 318.92
(2S,3R,4S,5R,6R)-2-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol
Catalogue No.:PA 04 93940
(2R,3S,4R,5R,6S)-6-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl Propionate
Catalogue No.:PA 04 93950
(2S,3R,4S,5S,6R)-2-(4-Chloro-3-((4-hydroxyphenyl)(methoxy)methyl)phenyl)-6-(hydroxymethyl)-2-methoxytetrahydro-2H-pyran-3,4,5-triol
Catalogue No.:PA 04 0931000
4-(5-Bromo-2-chlorobenzyl)phenol
Catalogue No.:PA 04 0931005
Molecular Formula : C13H10BrClO
Molecular Weight : 297.58
(1R)-1,4-Anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-D-glucitol
Catalogue No.:PA 04 0931002
1-Chloro-2-(4-ethoxybenzyl)-4-iodobenzene
Catalogue No.:PA 04 0931003
Molecular Formula : C15H14ClIO
Molecular Weight : 372.63
4-Bromo-1-chloro-2-[(2-ethoxyphenyl)methyl]benzene
Catalogue No.:PA 04 0931004
Ent-α-C Dapagliflozin
Catalogue No.:PA 04 0931006
Methyl 1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-D-glucopyranoside
Catalogue No.:PA 04 0931007
Dapagliflozin des-ethoxy impurity
Catalogue No.:PA 04 0931009
Molecular Formula : C19H21ClO5
Molecular Weight : 364.82
1,4-Dibromo-2-[(4-ethoxyphenyl)methyl]benzene
Catalogue No.:PA 04 0931010
Molecular Formula : C15H14Br2O
Molecular Weight : 370.08
5-Bromo-2-chloro-2’-ethoxy Benzophenone
Catalogue No.:PA 04 0931011
Molecular Formula : C15H12BrClO2
Molecular Weight : 339.61
(5-Bromo-2-chlorophenyl)(4-ethoxyphenyl)methanone
Catalogue No.:PA 04 0931012
Fluoro-Dapagliflozin
Catalogue No.:PA 04 0931008
Molecular Formula : C21H24ClFO5
Molecular Weight : 410.87
(5-Bromo-2-chlorophenyl)(4-ethyloxyphenyl)methanol
Catalogue No.:PA 04 0931013
Molecular Formula : C15H14BrClO2
Molecular Weight : 341.63
(2S,3R,4S,5R,6R)-6-(Acetoxymethyl)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-2-methoxytetrahydro-2H-pyran-3,4,5-triyl triacetate
Catalogue No.:PA 04 0931014
Molecular Formula : C30H35ClO11
Molecular Weight : 607.05
Dapagliflozin Triacetate
Catalogue No.:PA 04 0931015
(5-Bromo-2-chlorophenyl)(2-ethoxyphenyl)methanol
Catalogue No.:PA 04 0931016
(2R,3R,4R,5S,6S)-2-(Acetoxymethyl)-6-(4-chloro-3-(2-ethoxybenzyl)phenyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate
Catalogue No.:PA 04 0931017
1-C-[4-Chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-D-glucopyranose
Catalogue No.:PA 04 0931018
Dapagliflozin D7
Catalogue No.:PA STI 089046
Molecular Formula : C21H18D7ClO6
Molecular Weight : 415.92
(2S,3R,4R,5S,6R)-2-(4-Chloro-3-(4-ethoxy-3-ethylbenzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
Catalogue No.:PA 04 0931019
Molecular Formula : C23H29ClO6
Molecular Weight : 436.93
(3R,4R,5R)-2-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-5-((R)-1,2-dihydroxyethyl)tetrahydrofuran-3,4-diol
Catalogue No.:PA 04 0931020
Parishin B
Catalogue No.:PA 04 0931021
Molecular Formula : C32H40O19
Molecular Weight : 728.65
tert-Butyl(4-(2-chlorobenzyl)phenoxy)dimethylsilane
Catalogue No.:PA 04 0931022
Molecular Formula : C19H25ClOSi
Molecular Weight : 332.94
1-Bromo-2-chloro-3-(4-ethoxybenzyl)benzene
Catalogue No.:PA 04 0931023
1,4-Dichloro-2-(4-ethoxybenzyl)benzene
Catalogue No.:PA 04 0931024
Molecular Formula : C15H14Cl2O
Molecular Weight : 281.18
(3R,4S,5S,6R)-2-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-2-(((2R,3S,4R,5R,6S)-6-(4-chloro-3-(4-ethoxybenzyl)phenyl)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)methoxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
Catalogue No.:PA 04 0931025
(2S,3S,4S,5R,6S)-2-(2-(4-Ethoxybenzyl)-4-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
Catalogue No.:PA 04 0931026
Molecular Formula : C27H36O11
Molecular Weight : 536.57
2-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-6-vinyltetrahydro-2H-pyran-3,4,5-triol
Catalogue No.:PA 04 0931028
Molecular Formula : C22H25ClO5
Molecular Weight : 404.89
1-(4-Chloro-3-(4-ethoxybenzyl)phenyl)hexane-1,2,3,4,5,6-hexaol
Catalogue No.:PA 04 0931029
6-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-2,3,4,5-tetrahydroxy-6-oxohexanal
Catalogue No.:PA 04 0931030
(3R,4R,5R)-2-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-5-((R)-1,2-dihydroxyethyl)-2-methoxytetrahydrofuran-3,4-diol
Catalogue No.:PA 04 0931031
(2R,3R,4R,5S,6R)-2-(Acetoxymethyl)-6-(4-chloro-3-(4-ethoxybenzyl)phenyl)tetrahydro-2H-pyran-3,4,5-triyl Triacetate
Catalogue No.:PA 04 0931032
(2S,3S,4S)-2-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-5-((R)-1,2-diacetoxyethyl)tetrahydrofuran-3,4-diyl Diacetate
Catalogue No.:PA 04 0931033
(2S,3R,4S,5R,6R)-6-(Acetoxymethyl)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-2-(((2R,3R,4S,5R)-3,4,5-triacetoxy-6-oxotetrahydro-2H-pyran-2-yl)methoxy)tetrahydro-2H-pyran-3,4,5-triyl Triacetate
Catalogue No.:PA 04 0931034
Molecular Weight : 879.26
(2S,3R,4R,5S,6R)-2-(4-Bromo-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
Catalogue No.:PA 04 0931035
Molecular Formula : C23H27BrO7
Molecular Weight : 495.37
Dapagliflozin 3-O-Glucuronide
Catalogue No.:PA 04 0931036
(3R,4R,5R)-2-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-5-((S)-1,2-dihydroxyethyl)tetrahydrofuran-3,4-diol
Catalogue No.:PA 04 0931037
(2R,3R,4R,5S,6S)-2-(Acetoxymethyl)-6-(4-bromo-3-(4-ethoxybenzyl)phenyl)tetrahydro-2H-pyran-3,4,5-triyl Triacetate
Catalogue No.:PA 04 0931038
Molecular Formula : C29H33BrO10
Molecular Weight : 621.48
(2S,3R,4S,5S,6R)-2-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-2-(((2R,3S,4R,5R,6S)-6-(4-chloro-3-(4-ethoxybenzyl)phenyl)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)methoxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
Catalogue No.:PA 04 0931039
(2S,3R,4R,5S,6R)-2-(4-Chloro-3-((5-(2-chloro-5-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)benzyl)-2-ethoxyphenyl)(4-ethoxyphenyl)methyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
Catalogue No.:PA 04 0931040
(2S,3S,4R,5R,6R)-2-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yl Acetate
Catalogue No.:PA 04 0931041
(2R,3S,4R,5R,6S)-6-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-4,5-dihydroxy-2-(hydroxymethyl)tetrahydro-2H-pyran-3-yl Acetate
Catalogue No.:PA 04 0931042
(2S,3R,4S,5S,6R)-2-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl Acetate
Catalogue No.:PA 04 0931043
(2S,3S,4S,5R)-2-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-5-((R)-1,2-diacetoxyethyl)tetrahydrofuran-3,4-diyl Diacetate
Catalogue No.:PA 04 0931044
(2S,3R,4S,5R,6R)-6-(Acetoxymethyl)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-2-(((2R,3R,4R,5S,6S)-3,4,5-triacetoxy-6-(4-chloro-3-(4-ethoxybenzyl)phenyl)tetrahydro-2H-pyran-2-yl)methoxy)tetrahydro-2H-pyran-3,4,5-triyl Triacetate
Catalogue No.:PA 04 0931045
Molecular Formula : C56H62Cl2O19
Molecular Weight : 1109.99
1-Bromo-3-(4-ethoxybenzyl)benzene
Catalogue No.:PA 04 0931046
Molecular Formula : C15H15BrO
Molecular Weight : 291.19
Dapagliflozin Impurity S3A
Catalogue No.:PA 04 0931047
Molecular Formula : C28H31ClO9
Molecular Weight : 547
(2S,3R,4R,5S,6R)-2-(4-Chloro-3-(4-chloro-3-(4-ethoxybenzyl)benzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
Catalogue No.:PA 04 0931048
Molecular Formula : C28H30Cl2O6
Molecular Weight : 533.44
(2S,3R,4S,5S,6R)-2-(4-Chloro-3-((4-ethoxyphenyl)(methoxy)methyl)phenyl)-6-(hydroxymethyl)-2-methoxytetrahydro-2H-pyran-3,4,5-triol
Catalogue No.:PA 04 0931049
Molecular Formula : C23H29ClO8
Molecular Weight : 468.93
1-Chloro-2-((4-ethoxyphenyl)(methoxy)methyl)benzene
Catalogue No.:PA 04 0931050
Molecular Formula : C16H17ClO2
Molecular Weight : 276.76
(2R,3R,4S,5S,6R)-2-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-6-(hydroxymethyl)-2-methoxytetrahydro-2H-pyran-3,4,5-triol
Catalogue No.:PA 04 0931051
(2-Chloro-5-((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)-2-methoxytetrahydro-2H-pyran-2-yl)phenyl)(4-ethoxyphenyl)methanone
Catalogue No.:PA 04 0931052
Molecular Formula : C22H25ClO8
Molecular Weight : 452.88
(2S,3R,4S,5S,6R)-2-(4-Chloro-3-(2-ethoxybenzyl)phenyl)-6-(hydroxymethyl)-2-methoxytetrahydro-2H-pyran-3,4,5-triol
Catalogue No.:PA 04 0931053
2-((6-Chloro-2-methylpyrimidin-4-yl)amino)-N-(2,4-dichloro-6-methylphenyl)thiazole-5-carboxamide
Catalogue No.:PA 04 0931054
Molecular Formula : C16H12Cl3N5OS
Molecular Weight : 428.72
Rel-(2R,3R,4R,5S,6S)-2-(Acetoxymethyl)-6-(3-(4-ethoxybenzyl)phenyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate
Catalogue No.:PA 04 0931055
Molecular Formula : C29H34O10
Molecular Weight : 542.58
(2S,3R,4R,5S,6R)-2-(3-(4-Ethoxybenzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
Catalogue No.:PA 04 0931056
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