Delamanid and its Impurities
Delamanid, sold under the brand name Deltyba, is a medication used to treat tuberculosis. Specifically it is used, along with other antituberculosis medications. Reference standards of Delamanid API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
(R)-5-Methyl-5-((4-(4-(4-(trifluoromethoxy)phenoxy)piperidin-1-yl)phenoxy)methyl)-4,5-dihydrooxazol-2-amine
(R)-5-Methyl-5-((4-(4-(4-(trifluoromethoxy)phenoxy)piperidin-1-yl)phenoxy)methyl)-4,5-dihydrooxazol-2-amine
Catalogue No.:PA 31 0991001
CAS :
1202875-92-0
Molecular Formula : C23H26F3N3O4
Molecular Weight : 465.47
(S)-2-Methyl-6-nitro-2-((4-(4-(4-(trifluoromethoxy)phenoxy)piperidin-1-yl)phenoxy)methyl)-2,3-dihydroimidazo[2,1-b]oxazole;
(S)-2-Methyl-6-nitro-2-((4-(4-(4-(trifluoromethoxy)phenoxy)piperidin-1-yl)phenoxy)methyl)-2,3-dihydroimidazo[2,1-b]oxazole;
Catalogue No.:PA 31 0991003
CAS :
681505-01-1
Molecular Formula : C25H25F3N4O6
Molecular Weight : 534.49
4-(4-((2,4-Dioxothiazolidin-5-ylidene)methyl)-2-methoxyphenoxy)-3-(trifluoromethyl)benzonitrile
4-(4-((2,4-Dioxothiazolidin-5-ylidene)methyl)-2-methoxyphenoxy)-3-(trifluoromethyl)benzonitrile
Catalogue No.:PA 31 0991004
CAS :
1055361-35-7
Molecular Formula : C19H11F3N2O4S
Molecular Weight : 420.36
(R)-1-(4-(2,3-Dihydroxy-2-methylpropoxy)phenyl)-4-(4-(trifluoromethoxy)phenoxy)piperidine 1-oxide
(R)-1-(4-(2,3-Dihydroxy-2-methylpropoxy)phenyl)-4-(4-(trifluoromethoxy)phenoxy)piperidine 1-oxide
Catalogue No.:PA 31 0991005
CAS :
NA
Molecular Formula : C22H26F3NO6
Molecular Weight : 457.45
(R)-3-((R)-2-Hydroxy-2-methyl-3-(4-(4-(4-(trifluoromethoxy)phenoxy)piperidin-1-yl)phenoxy)propoxy)-2-methylpropane-1,2-diol
(R)-3-((R)-2-Hydroxy-2-methyl-3-(4-(4-(4-(trifluoromethoxy)phenoxy)piperidin-1-yl)phenoxy)propoxy)-2-methylpropane-1,2-diol
Catalogue No.:PA 31 0991007
CAS :
NA
Molecular Formula : C26H34F3NO7
Molecular Weight : 529.55
(R)-2-Methyl-3-(4-(4-(4-(trifluoromethoxy)phenoxy)piperidin-1-yl)-3-(4-(4-(4-(trifluoromethoxy)phenoxy)piperidin-1-yl)phenoxy)phenoxy)propane-1,2-diol
(R)-2-Methyl-3-(4-(4-(4-(trifluoromethoxy)phenoxy)piperidin-1-yl)-3-(4-(4-(4-(trifluoromethoxy)phenoxy)piperidin-1-yl)phenoxy)phenoxy)propane-1,2-diol
Catalogue No.:PA 31 0991008
CAS :
NA
Molecular Formula : C40H42F6N2O8
Molecular Weight : 792.77
(R)-2-Methyl-3-(4-(4-(4-(trifluoromethoxy)phenoxy)piperidin-1-yl)phenoxy)propane-1,2-diol
(R)-2-Methyl-3-(4-(4-(4-(trifluoromethoxy)phenoxy)piperidin-1-yl)phenoxy)propane-1,2-diol
Catalogue No.:PA 31 0991009
CAS :
1318735-00-0
Molecular Formula : C22H26F3NO5
Molecular Weight : 441.45
(S)-2-Methyl-3-(4-(4-(4-(trifluoromethoxy)phenoxy)piperidin-1-yl)phenoxy)propane-1,2-diyl dimethanesulfonate
(S)-2-Methyl-3-(4-(4-(4-(trifluoromethoxy)phenoxy)piperidin-1-yl)phenoxy)propane-1,2-diyl dimethanesulfonate
Catalogue No.:PA 31 0991011
CAS :
NA
Molecular Formula : C24H30F3NO9S2
Molecular Weight : 597.62
(R)-1-(4-((2-Methyloxiran-2-yl)methoxy)-2-(4-(4-(4-(trifluoromethoxy)phenoxy)piperidin-1-yl)phenoxy)phenyl)-4-(4-(trifluoromethoxy)phenoxy)piperidine
(R)-1-(4-((2-Methyloxiran-2-yl)methoxy)-2-(4-(4-(4-(trifluoromethoxy)phenoxy)piperidin-1-yl)phenoxy)phenyl)-4-(4-(trifluoromethoxy)phenoxy)piperidine
Catalogue No.:PA 31 0991013
CAS :
NA
Molecular Formula : C40H40F6N2O7
Molecular Weight : 774.76
(R)-1-(4-((2-Methyl-6-nitro-2,3-dihydroimidazo[2,1-b]oxazol-2-yl)methoxy)phenyl)pyridin-1-ium Chloride
(R)-1-(4-((2-Methyl-6-nitro-2,3-dihydroimidazo[2,1-b]oxazol-2-yl)methoxy)phenyl)pyridin-1-ium Chloride
Catalogue No.:PA 31 0991014
CAS :
NA
Molecular Formula : C18H17ClN4O4
Molecular Weight : 388.81
