Dihydrostreptomycin and its Impurities

Dihydrostreptomycin is an aminoglycoside antibiotic, chemically derived from streptomycin by hydrogenation. It was widely used in the past for bacterial infections but is now largely restricted to veterinary medicine due to toxicity concerns in humans. Reference standards of Dihydrostreptomycin API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.