diltiazem hydrochloride and its Impurities

An  antianginal, and  antiarrhythmic drug. Diltiazem Hydrochloride is a calcium channel blocker. It is used to treat hypertension and angina pectoris. This potent vasodilator, is a a 1,4-thiazepine derivative.. Reference standards of Diltiazem Hydrochloride API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below

Displaying 47 results for diltiazem hydrochloride Impurities
Drug Reference Standards & Impurity Synthesis in India
PA 04 26000

Diltiazem Hydrochloride

Diltiazem Hydrochloride


  • Catalogue No.:PA 04 26000

  • CAS :

    33286-22-5

  • Molecular Formula : C22H27ClN2O4S

  • Molecular Weight : 450.98

Drug Reference Standards & Impurity Synthesis in India
PA 04 26010

Diltiazem - Impurity A

(2R,3S)-5-[2-(Dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepine-3-yl Acetate


  • Catalogue No.:PA 04 26010

  • CAS :

    111188-71-7

  • Molecular Formula : C22H26N2O4S

  • Molecular Weight : 414.52

Drug Reference Standards & Impurity Synthesis in India
PA 04 26011

Diltiazem - Impurity A (Hydrochloride Salt)

(2R,3S)-5-[2-(Dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepine-3-yl Acetate Hydrochloride Salt


  • Catalogue No.:PA 04 26011

  • CAS :

    103532-27-0

  • Molecular Formula : C22H27ClN2O4S

  • Molecular Weight : 450.98

Drug Reference Standards & Impurity Synthesis in India
PA 04 26020

Diltiazem - Impurity B

Des[5-(2-dimethylamino)ethyl] Diltiazem


  • Catalogue No.:PA 04 26020

  • CAS :

    87447-47-0

  • Molecular Formula : C18H17NO4S

  • Molecular Weight : 343.40

Drug Reference Standards & Impurity Synthesis in India
PA 04 26030

Diltiazem - Impurity C

O-Desmethyl Diltiazem Hydrochloride


  • Catalogue No.:PA 04 26030

  • CAS :

    NA

  • Molecular Formula : C21H25ClN2O4S

  • Molecular Weight : 436.95

Drug Reference Standards & Impurity Synthesis in India
PA 04 26040

Diltiazem - Impurity D

N-Desmethyl Diltiazem Hydrochloride


  • Catalogue No.:PA 04 26040

  • CAS :

    130606-60-9

  • Molecular Formula : C21H25ClN2O4S

  • Molecular Weight : 436.95

Drug Reference Standards & Impurity Synthesis in India
PA 04 26050

Diltiazem - Impurity E

Des[3-Acetyl-5-(2-dimethylamino)ethyl] Diltiazem


  • Catalogue No.:PA 04 26050

  • CAS :

    42399-49-5

  • Molecular Formula : C16H15NO3S

  • Molecular Weight : 301.36

Drug Reference Standards & Impurity Synthesis in India
PA 04 26060

Diltiazem - Impurity F

Desacetyl Diltiazem


  • Catalogue No.:PA 04 26060

  • CAS :

    42399-40-6

  • Molecular Formula : C20H24N2O3S

  • Molecular Weight : 372.48

Drug Reference Standards & Impurity Synthesis in India
PA 04 26061

Diltiazem - Impurity F (Hydrochloride Salt)

Desacetyl Diltiazem Hydrochloride


  • Catalogue No.:PA 04 26061

  • CAS :

    75472-91-2

  • Molecular Formula : C20H25ClN2O3S

  • Molecular Weight : 408.94

Drug Reference Standards & Impurity Synthesis in India
PA 04 26510

Diltiazem Sulphoxide

Diltiazem Sulphoxide


  • Catalogue No.:PA 04 26510

  • CAS :

    370094-12-5

  • Molecular Formula : C22H26N2O5S

  • Molecular Weight : 430.52

Drug Reference Standards & Impurity Synthesis in India
PA 04 26520

Diltiazem N-Oxide

Diltiazem N-Oxide


  • Catalogue No.:PA 04 26520

  • CAS :

    142843-04-7

  • Molecular Formula : C22H26N2O5S

  • Molecular Weight : 430.52

Drug Reference Standards & Impurity Synthesis in India
PA 04 26540

N,N-DiDesmethyl Diltiazem Hydrochloride

N,N-DiDesmethyl Diltiazem Hydrochloride


  • Catalogue No.:PA 04 26540

  • CAS :

    116050-35-2

  • Molecular Formula : C20H23ClN2O4S

  • Molecular Weight : 422.93

Drug Reference Standards & Impurity Synthesis in India
PA 04 26550

Diltiazem Maleate

Diltiazem Maleate


  • Catalogue No.:PA 04 26550

  • CAS :

    139492-78-7

  • Molecular Formula : C26H30N2O8S

  • Molecular Weight : 530.59

Drug Reference Standards & Impurity Synthesis in India
PA 04 26560

N-Desmethyl Desacetyl Diltiazem Hydrochloride Salt

N-Desmethyl Desacetyl Diltiazem Hydrochloride Salt


  • Catalogue No.:PA 04 26560

  • CAS :

    68767-04-4

  • Molecular Formula : C19H23ClN2O3S

  • Molecular Weight : 394.92

Drug Reference Standards & Impurity Synthesis in India
PA 04 26570

(2S,3S)-5-(2-Aminoethyl)-2,3-dihydro-3-hydroxy-2-(4-hydroxyphenyl)-1,5-benzothiazepin-4(5H)-one

(2S,3S)-5-(2-Aminoethyl)-2,3-dihydro-3-hydroxy-2-(4-hydroxyphenyl)-1,5-benzothiazepin-4(5H)-one


  • Catalogue No.:PA 04 26570

  • CAS :

    115992-91-1

  • Molecular Formula : C17H18N2O3S

  • Molecular Weight : 330.4

Drug Reference Standards & Impurity Synthesis in India
PA 04 26590

(2S,3S)-2-(4-Methoxyphenyl)-5-methyl-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]thiazepin-3-yl Acetate

(2S,3S)-2-(4-Methoxyphenyl)-5-methyl-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]thiazepin-3-yl Acetate


  • Catalogue No.:PA 04 26590

  • CAS :

    125473-53-2

  • Molecular Formula : C19H19NO4S

  • Molecular Weight : 357.42

Drug Reference Standards & Impurity Synthesis in India
PA 04 26600

(2S,3S)-2-(4-Methoxyphenyl)-4-oxo-5-vinyl-2,3,4,5-tetrahydrobenzo[b][1,4]thiazepin-3-yl Acetate

(2S,3S)-2-(4-Methoxyphenyl)-4-oxo-5-vinyl-2,3,4,5-tetrahydrobenzo[b][1,4]thiazepin-3-yl Acetate


  • Catalogue No.:PA 04 26600

  • CAS :

    NA

  • Molecular Formula : C20H19NO4S

  • Molecular Weight : 369.43

Drug Reference Standards & Impurity Synthesis in India
PA 04 26610

Deacetyl Diltiazem N-Oxide

Deacetyl Diltiazem N-Oxide


  • Catalogue No.:PA 04 26610

  • CAS :

    122619-90-3

  • Molecular Formula : C20H24N2O4S

  • Molecular Weight : 388.48

Drug Reference Standards & Impurity Synthesis in India
PA 04 26620

Deacetyl-O-demethyldiltiazem

Deacetyl-O-demethyldiltiazem


  • Catalogue No.:PA 04 26620

  • CAS :

    84903-82-2

  • Molecular Formula : C19H22N2O3S

  • Molecular Weight : 358.45

Drug Reference Standards & Impurity Synthesis in India
PA 04 26630

Deacetyl-N,O-didemethyldiltiazem

Deacetyl-N,O-didemethyldiltiazem


  • Catalogue No.:PA 04 26630

  • CAS :

    86408-42-6

  • Molecular Formula : C18H20N2O3S

  • Molecular Weight : 344.43

Drug Reference Standards & Impurity Synthesis in India
PA USP1205003

Diltiazem Hydrochloride (1205003)

Diltiazem Hydrochloride (1205003)


  • Catalogue No.:PA USP1205003

  • CAS :

    33286-22-5

  • Molecular Formula : NA

  • Molecular Weight : NA

Drug Reference Standards & Impurity Synthesis in India
PA BP726RB

diltiazem hydrochloride (726RB)

diltiazem hydrochloride (726RB)


  • Catalogue No.:PA BP726RB

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

Drug Reference Standards & Impurity Synthesis in India
PA USP1205014

Diltiazem Related Compound A (AS) (trans-diltiazem hydrochloride) (1205014)

Diltiazem Related Compound A (AS) (trans-diltiazem hydrochloride) (1205014)


  • Catalogue No.:PA USP1205014

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

Drug Reference Standards & Impurity Synthesis in India
PA USP1171706

Desacetyl Diltiazem Hydrochloride (1171706)

Desacetyl Diltiazem Hydrochloride (1171706)


  • Catalogue No.:PA USP1171706

  • CAS :

    23515-45-9

  • Molecular Formula : NA

  • Molecular Weight : NA

Drug Reference Standards & Impurity Synthesis in India
PA JP0253

Diltiazem Hydrochloride (JP 0253)

Diltiazem Hydrochloride (JP 0253)


  • Catalogue No.:PA JP0253

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

Drug Reference Standards & Impurity Synthesis in India
PA IPIPRS 01 13

Diltiazem Hydrochloride (IPRS/01/13)-from IPC

Diltiazem Hydrochloride (IPRS/01/13)-from IPC


  • Catalogue No.:PA IPIPRS 01 13

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

Drug Reference Standards & Impurity Synthesis in India
PA STI 026951

Desacetyl Diltiazem-d3 Hydrochloride

Desacetyl Diltiazem-d3 Hydrochloride


  • Catalogue No.:PA STI 026951

  • CAS :

    NA

  • Molecular Formula : C20H22D3ClN2O3S

  • Molecular Weight : 411.96

Drug Reference Standards & Impurity Synthesis in India
PA 04 0261000

(2S,3S)-3-Hydroxy-2-(4-methoxy-3-methylphenyl)-2,3-dihydrobenzo[b][1,4]thiazepin-4(5H)-one

(2S,3S)-3-Hydroxy-2-(4-methoxy-3-methylphenyl)-2,3-dihydrobenzo[b][1,4]thiazepin-4(5H)-one


  • Catalogue No.:PA 04 0261000

  • CAS :

    NA

  • Molecular Formula : C17H17NO3S

  • Molecular Weight : 315.39

Drug Reference Standards & Impurity Synthesis in India
PA 04 0261001

Deacetyl o-Demethyl Diltiazem

Deacetyl o-Demethyl Diltiazem


  • Catalogue No.:PA 04 0261001

  • CAS :

    NA

  • Molecular Formula : C20H23NO3S

  • Molecular Weight : 357.47

Drug Reference Standards & Impurity Synthesis in India
PA 04 0261003

(2S-trans)-Diltiazem Hydrochloride

(2S-trans)-Diltiazem Hydrochloride


  • Catalogue No.:PA 04 0261003

  • CAS :

    103532-26-9

  • Molecular Formula : C22H27ClN2O4S

  • Molecular Weight : 450.98

Drug Reference Standards & Impurity Synthesis in India
PA 04 0261002

(2R,3S)-5-(2-(Dimethylamino)ethyl)-3-hydroxy-2-(4-methoxyphenyl)-2,3-dihydrobenzo[b][1,4]thiazepin-4(5H)-one

(2R,3S)-5-(2-(Dimethylamino)ethyl)-3-hydroxy-2-(4-methoxyphenyl)-2,3-dihydrobenzo[b][1,4]thiazepin-4(5H)-one


  • Catalogue No.:PA 04 0261002

  • CAS :

    91926-66-8

  • Molecular Formula : C20H24N2O3S

  • Molecular Weight : 372.48

Drug Reference Standards & Impurity Synthesis in India
PA 04 0261005

Deacetyl-O-demethyl diltiazem hydrochloride

Deacetyl-O-demethyl diltiazem hydrochloride


  • Catalogue No.:PA 04 0261005

  • CAS :

    96252-32-3

  • Molecular Formula : C19H23ClN2O3S

  • Molecular Weight : 394.91

Drug Reference Standards & Impurity Synthesis in India
PA 04 0261006

Deacetyl-N,O-didesmethyldiltiazem Hydrochloride

Deacetyl-N,O-didesmethyldiltiazem Hydrochloride


  • Catalogue No.:PA 04 0261006

  • CAS :

    142926-09-8

  • Molecular Formula : C18H21ClN2O3S

  • Molecular Weight : 380.89

Drug Reference Standards & Impurity Synthesis in India
PA 04 0261007

rel-(2R,3S)-3-Hydroxy-2-(4-methoxyphenyl)-2,3-dihydrobenzo[b][1,4]thiazepin-4(5H)-one

rel-(2R,3S)-3-Hydroxy-2-(4-methoxyphenyl)-2,3-dihydrobenzo[b][1,4]thiazepin-4(5H)-one


  • Catalogue No.:PA 04 0261007

  • CAS :

    30825-34-4

  • Molecular Formula : C16H15NO3S

  • Molecular Weight : 301.36

Drug Reference Standards & Impurity Synthesis in India
PAI 04 026001

5-(2-(((1-Chloroethoxy)carbonyl)(methyl)amino)ethyl)-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]thiazepin-3-yl Acetate

5-(2-(((1-Chloroethoxy)carbonyl)(methyl)amino)ethyl)-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]thiazepin-3-yl Acetate


  • Catalogue No.:PAI 04 026001

  • CAS :

    147595-36-6

  • Molecular Formula : C24H27ClN2O6S

  • Molecular Weight : 507

Drug Reference Standards & Impurity Synthesis in India
PA 04 0261008

Des[5-(2-Dimethylamino)Ethyl] N-Methyl Diltiazem

Des[5-(2-Dimethylamino)Ethyl] N-Methyl Diltiazem


  • Catalogue No.:PA 04 0261008

  • CAS :

    2067323-40-2

  • Molecular Formula : C19H19NO4S

  • Molecular Weight : 357.42

Drug Reference Standards & Impurity Synthesis in India
PA 04 0261009

Des[5-(2-dimethylamino)ethyl] Diltiazem 5-Ethenyl

Des[5-(2-dimethylamino)ethyl] Diltiazem 5-Ethenyl


  • Catalogue No.:PA 04 0261009

  • CAS :

    2055466-64-1

  • Molecular Formula : C20H19NO4S

  • Molecular Weight : 369.44

Drug Reference Standards & Impurity Synthesis in India
PA 04 0261010

3,3-Dibutyl-7-(dimethylamino)-4-hydroxy-5-(4-methoxyphenyl)-2,3,4,5-tetrahydrobenzo[b]thiepine 1,1-dioxide

3,3-Dibutyl-7-(dimethylamino)-4-hydroxy-5-(4-methoxyphenyl)-2,3,4,5-tetrahydrobenzo[b]thiepine 1,1-dioxide


  • Catalogue No.:PA 04 0261010

  • CAS :

    361374-18-7

  • Molecular Formula : C27H39NO4S

  • Molecular Weight : 473.67

Drug Reference Standards & Impurity Synthesis in India
PA 04 0261011

5-(2-(Dimethylamino)ethyl)-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]thiazepin-3-yl Acetate

5-(2-(Dimethylamino)ethyl)-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]thiazepin-3-yl Acetate


  • Catalogue No.:PA 04 0261011

  • CAS :

    56209-45-1

  • Molecular Formula : C22H26N2O4S

  • Molecular Weight : 414.52

Drug Reference Standards & Impurity Synthesis in India
PA 04 0261012

(2S,3S)-2-(4-Methoxyphenyl)-5-(2-(methyl(nitroso)amino)ethyl)-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]thiazepin-3-yl Acetate

(2S,3S)-2-(4-Methoxyphenyl)-5-(2-(methyl(nitroso)amino)ethyl)-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]thiazepin-3-yl Acetate


  • Catalogue No.:PA 04 0261012

  • CAS :

    3036581-85-5

  • Molecular Formula : C21H23N3O5S

  • Molecular Weight : 429.49

Drug Reference Standards & Impurity Synthesis in India
PA 04 0261013

N-(2-((2S,3S)-3-Hydroxy-2-(4-methoxyphenyl)-4-oxo-3,4-dihydrobenzo[b][1,4]thiazepin-5(2H)-yl)ethyl)-N-methylnitrous amide

N-(2-((2S,3S)-3-Hydroxy-2-(4-methoxyphenyl)-4-oxo-3,4-dihydrobenzo[b][1,4]thiazepin-5(2H)-yl)ethyl)-N-methylnitrous amide


  • Catalogue No.:PA 04 0261013

  • CAS :

    NA

  • Molecular Formula : C19H21N3O4S

  • Molecular Weight : 387.45

Drug Reference Standards & Impurity Synthesis in India
PA 04 0261015

Desacetyl Diltiazem Hydrochloride (Mixture)

Desacetyl Diltiazem Hydrochloride (Mixture)


  • Catalogue No.:PA 04 0261015

  • CAS :

    23515-45-9

  • Molecular Formula : C20H25ClN2O3S

  • Molecular Weight : 408.94

Drug Reference Standards & Impurity Synthesis in India
PA 04 0261016

(2S,3S)-5-(2-(Ethyl(methyl)amino)ethyl)-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]thiazepin-3-yl acetate

(2S,3S)-5-(2-(Ethyl(methyl)amino)ethyl)-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]thiazepin-3-yl acetate


  • Catalogue No.:PA 04 0261016

  • CAS :

    138778-32-2

  • Molecular Formula : C23H28N2O4S

  • Molecular Weight : 428.55

Drug Reference Standards & Impurity Synthesis in India
PA 04 0261017

(2S,3S)-2-(4-Methoxyphenyl)-5-(2-(N-methylformamido)ethyl)-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]thiazepin-3-yl acetate

(2S,3S)-2-(4-Methoxyphenyl)-5-(2-(N-methylformamido)ethyl)-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]thiazepin-3-yl acetate


  • Catalogue No.:PA 04 0261017

  • CAS :

    1643948-42-8

  • Molecular Formula : C22H24N2O5S

  • Molecular Weight : 428.5

Drug Reference Standards & Impurity Synthesis in India
PA 04 0261018

(2R,3R)-3-Hydroxy-2-(4-methoxy-3-methylphenyl)-2,3-dihydrobenzo[b][1,4]thiazepin-4(5H)-one

(2R,3R)-3-Hydroxy-2-(4-methoxy-3-methylphenyl)-2,3-dihydrobenzo[b][1,4]thiazepin-4(5H)-one


  • Catalogue No.:PA 04 0261018

  • CAS :

    42399-51-9

  • Molecular Formula : C17H17NO3S

  • Molecular Weight : 315.39

Drug Reference Standards & Impurity Synthesis in India
PA BSC 02604828

Des[3-Acetyl-5-(2-dimethylamino)ethyl] Diltiazem (BSC)

Des[3-Acetyl-5-(2-dimethylamino)ethyl] Diltiazem


  • Catalogue No.:PA BSC 02604828

  • CAS :

    42399-49-5

  • Molecular Formula : C16H15NO3S

  • Molecular Weight : 301.36

Drug Reference Standards & Impurity Synthesis in India
PA 04 0260011

Diltiazem - Impurity A (Formate Salt)

(2R,3S)-5-[2-(Dimethylamino)ethyl]-2-(4- methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5- benzothiazepin-3-yl acetate Formate


  • Catalogue No.:PA 04 0260011

  • CAS :

    NA

  • Molecular Formula : C23H28N2O6S

  • Molecular Weight : 460.55

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