donepezil and its Impurities

A reversible acetylcholinesterase inhibitor, Donepezil is used for the treatment of of Alzheimer's disease. It is a medication used in palliative treatment. It works by inhibiting the hydrolysis of acetylcholine.. Reference standards of Donepezil API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below

Displaying 51 results for donepezil Impurities
PA 04 39000

Donepezil - API

Donepezil


  • Catalogue No.:PA 04 39000

  • CAS :

    120014-06-4

  • Molecular Formula : C24H29NO3

  • Molecular Weight : 379.49

PA 04 40010

Donepezil - Impurity A

Desbenzyl Donepezil Hydrochloride


  • Catalogue No.:PA 04 40010

  • CAS :

    120013-39-0

  • Molecular Formula : C17H24ClNO3

  • Molecular Weight : 325.83

PA 04 40020

Donepezil - Impurity B

5,6-Dimethoxy-1-indanone


  • Catalogue No.:PA 04 40020

  • CAS :

    2107-69-9

  • Molecular Formula : C11H12O3

  • Molecular Weight : 192.21

PA 04 40510

Donepezil N-Oxide

Donepezil N-Oxide


  • Catalogue No.:PA 04 40510

  • CAS :

    120013-84-5

  • Molecular Formula : C24H29NO4

  • Molecular Weight : 395.49

PA 04 40520

Donepezil Alkene Pyridine N-oxide

Donepezil Alkene Pyridine N-oxide


  • Catalogue No.:PA 04 40520

  • CAS :

    NA

  • Molecular Formula : C17H15NO4

  • Molecular Weight : 297.31

PA 04 40530

Donepezil Pyridine Analog Impurity

Donepezil Pyridine Analog Impurity


  • Catalogue No.:PA 04 40530

  • CAS :

    4803-57-0

  • Molecular Formula : C17H17NO3

  • Molecular Weight : 283.32

PA 04 40540

Donepezil - Impurity F

Donepezil Dehydro Impurity


  • Catalogue No.:PA 04 40540

  • CAS :

    145546-80-1

  • Molecular Formula : C24H27NO3

  • Molecular Weight : 377.48

PA 04 40550

Dehydrodeoxy Donepezil

Dehydrodeoxy Donepezil


  • Catalogue No.:PA 04 40550

  • CAS :

    120013-45-8

  • Molecular Formula : C24H29NO2

  • Molecular Weight : 363.49

PA 04 40560

Deoxy Donepezil Hydrochloride

Deoxy Donepezil Hydrochloride


  • Catalogue No.:PA 04 40560

  • CAS :

    1034439-57-0

  • Molecular Formula : C24H32ClNO2

  • Molecular Weight : 401.97

PA 04 40570

3-Hydroxy Donepezil

3-Hydroxy Donepezil


  • Catalogue No.:PA 04 40570

  • CAS :

    2097683-67-3

  • Molecular Formula : C24H29NO4

  • Molecular Weight : 395.49

PA 04 40580

Hydroxy Donepezil

Hydroxy Donepezil


  • Catalogue No.:PA 04 40580

  • CAS :

    197010-20-1

  • Molecular Formula : C24H29NO4

  • Molecular Weight : 395.49

PA 04 40590

Donepezil Benzyl Bromide

Donepezil Benzyl Bromide


  • Catalogue No.:PA 04 40590

  • CAS :

    844694-85-5

  • Molecular Formula : C31H36BrNO3

  • Molecular Weight : 550.53

PA 04 40600

Donepezil Open-Ring Keto Acid

Donepezil Open-Ring Keto Acid


  • Catalogue No.:PA 04 40600

  • CAS :

    197010-25-6

  • Molecular Formula : C24H29NO5

  • Molecular Weight : 411.49

PA 04 40610

Donepezil Deoxy

Donepezil Deoxy


  • Catalogue No.:PA 04 40610

  • CAS :

    844694-84-4

  • Molecular Formula : C24H31NO2

  • Molecular Weight : 365.51

PA 04 40620

Donepezil Pyridine N-Oxide

Donepezil Pyridine N-Oxide


  • Catalogue No.:PA 04 40620

  • CAS :

    896134-07-9

  • Molecular Formula : C17H17NO4

  • Molecular Weight : 299.32

PA 04 40630

4,5-Dimethoxy-1-indanone

4,5-Dimethoxy-1-indanone


  • Catalogue No.:PA 04 40630

  • CAS :

    6342-80-9

  • Molecular Formula : C11H12O3

  • Molecular Weight : 192.21

PA 04 40640

4,6-Dimethoxy-2,3-dihydroinden-1-one

4,6-Dimethoxy-2,3-dihydroinden-1-one


  • Catalogue No.:PA 04 40640

  • CAS :

    13336-32-8

  • Molecular Formula : C11H12O3

  • Molecular Weight : 192.21

PA 04 40650

4,7-Dimethoxy-1-indanone

4,7-Dimethoxy-1-indanone


  • Catalogue No.:PA 04 40650

  • CAS :

    52428-09-8

  • Molecular Formula : C11H12O3

  • Molecular Weight : 192.21

PA 04 40660

5,7-Dimethoxy-2,3-dihydroinden-1-one

5,7-Dimethoxy-2,3-dihydroinden-1-one


  • Catalogue No.:PA 04 40660

  • CAS :

    880-87-5

  • Molecular Formula : C11H12O3

  • Molecular Weight : 192.21

PA 04 40670

6,7-Dimethoxy-2,3-dihydroinden-1-one

6,7-Dimethoxy-2,3-dihydroinden-1-one


  • Catalogue No.:PA 04 40670

  • CAS :

    57441-74-4

  • Molecular Formula : C11H12O3

  • Molecular Weight : 192.21

PA 04 40680

1-Benzyl-4-[(6,7-dimethoxy-1-oxoindan-2-yl)methyl]piperidine

1-Benzyl-4-[(6,7-dimethoxy-1-oxoindan-2-yl)methyl]piperidine


  • Catalogue No.:PA 04 40680

  • CAS :

    736104-42-0

  • Molecular Formula : C24H29NO3

  • Molecular Weight : 379.49

PA 04 40690

Donepezil Dehydro Impurity (E/Z mixture)

Donepezil Dehydro Impurity (E/Z mixture)


  • Catalogue No.:PA 04 40690

  • CAS :

    120014-07-5

  • Molecular Formula : C24H27NO3

  • Molecular Weight : 377.48

PA 04 40700

Donepezil - Impurity G

(2RS)-2-[(1-benzyl-1,2,3,4-tetrahydropyridin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydro-1Hinden-1-one


  • Catalogue No.:PA 04 40700

  • CAS :

    NA

  • Molecular Formula : C24H27NO3

  • Molecular Weight : 377.48

PA 04 40710

6-O-Desmethyl Donepezil

6-O-Desmethyl Donepezil


  • Catalogue No.:PA 04 40710

  • CAS :

    120013-56-1

  • Molecular Formula : C23H27NO3

  • Molecular Weight : 365.47

PA 04 40720

5,6-Dimethoxy-2-(4-piperidinyl)methyleneindan-1-one

5,6-Dimethoxy-2-(4-piperidinyl)methyleneindan-1-one


  • Catalogue No.:PA 04 40720

  • CAS :

    149874-91-9

  • Molecular Formula : C17H21NO3

  • Molecular Weight : 287.35

PA 04 40730

Donepezil - Impurity A (Freebase)

5,6-Dimethoxy-2-[(4-piperidyl)methyl]indan-1-one


  • Catalogue No.:PA 04 40730

  • CAS :

    120014-30-4

  • Molecular Formula : C17H23NO3

  • Molecular Weight : 289.37

PA STI 011340

1-Benzyl-4-[(5,6-dimethoxy-1-oxoindan-2-ylidene)methyl]piperidine-13C3

1-Benzyl-4-[(5,6-dimethoxy-1-oxoindan-2-ylidene)methyl]piperidine-13C3


  • Catalogue No.:PA STI 011340

  • CAS :

    1185239-87-5

  • Molecular Formula : C2113C3H27NO3

  • Molecular Weight : 380.45

PA STI 028340

5-O-Desmethyl Donepezil-d5

5-O-Desmethyl Donepezil-d5


  • Catalogue No.:PA STI 028340

  • CAS :

    1189929-21-2

  • Molecular Formula : C23H22D5NO3

  • Molecular Weight : 370.50

PA STI 028350

6-O-Desmethyl Donepezil-d5

6-O-Desmethyl Donepezil-d5


  • Catalogue No.:PA STI 028350

  • CAS :

    1189443-74-0

  • Molecular Formula : C23H22D5NO3

  • Molecular Weight : 370.50

PA STI 032760

4-[(2,3-Dihydro-5,6-dimethoxy-1-oxo-1H-inden-2-yl)methyl]-1,1-bis(phenylmethyl)piperidinium-d14 Bromide

4-[(2,3-Dihydro-5,6-dimethoxy-1-oxo-1H-inden-2-yl)methyl]-1,1-bis(phenylmethyl)piperidinium-d14 Bromide


  • Catalogue No.:PA STI 032760

  • CAS :

    NA

  • Molecular Formula : C31H22D14BrNO3

  • Molecular Weight : 564.61

PA STI 033470

5,6-Dimethoxy-1-indanone-13C3

5,6-Dimethoxy-1-indanone-13C3


  • Catalogue No.:PA STI 033470

  • CAS :

    1185155-55-8

  • Molecular Formula : C813C3H12O3

  • Molecular Weight : 195.19

PA STI 036190

Donepezil-d7 Hydrochloride

Donepezil-d7 Hydrochloride


  • Catalogue No.:PA STI 036190

  • CAS :

    1261394-20-0

  • Molecular Formula : C24H23D7ClNO3

  • Molecular Weight : 423.00

PA STI 036191

Donepezil-d5

Donepezil-d5


  • Catalogue No.:PA STI 036191

  • CAS :

    1128086-25-8

  • Molecular Formula : C24H24D5NO3

  • Molecular Weight : 384.52

PA STI 036200

Donepezil-13C3 Hydrochloride

Donepezil-13C3 Hydrochloride


  • Catalogue No.:PA STI 036200

  • CAS :

    1246814-90-3

  • Molecular Formula : C2113C3H30ClNO3

  • Molecular Weight : 418.93

PA USP1171819

Desbenzyl Donepezil Hydrochloride (5,6-dimethoxy-2-(piperidin-4-ylmethyl)indan-1-one hydrochloride) (1171819)


  • Catalogue No.:PA USP1171819

  • CAS :

    120013-39-0

  • Molecular Formula :

  • Molecular Weight : NA

PA USP1224970

Donepezil-N-Oxide (1224970)


  • Catalogue No.:PA USP1224970

  • CAS :

    120013-84-5

  • Molecular Formula :

  • Molecular Weight : NA

PA USP1224992

Donepezil Related Compound A ((E)-2-[(1-benzylpiperidin-4-yl)methylene]-5,6-dimethoxyindan-1-one) (1224992)


  • Catalogue No.:PA USP1224992

  • CAS :

    145546-80-1

  • Molecular Formula :

  • Molecular Weight : NA

PA USP1224981

Donepezil Hydrochloride (1224981)


  • Catalogue No.:PA USP1224981

  • CAS :

    884740-09-4

  • Molecular Formula :

  • Molecular Weight : NA

PA 04 40050

Donepezil - Impurity E (Bromide Salt)

1-Benzyl-4-(5,6-dimethoxy-1-oxoindan-2-yl)methylpyridinium Bromide


  • Catalogue No.:PA 04 40050

  • CAS :

    231283-82-2

  • Molecular Formula : C24H24BrNO3

  • Molecular Weight : 454.36

PA 04 40740

5,6-Dimethoxy-2-(4-pyridylmethylene)-1-indanone

5,6-Dimethoxy-2-(4-pyridylmethylene)-1-indanone


  • Catalogue No.:PA 04 40740

  • CAS :

    4803-74-1

  • Molecular Formula : C17H15NO3

  • Molecular Weight : 281.31

PA 04 40750

2,3-Dihydro-5,6-dimethoxy-2-[(1-oxido-4-pyridinyl)methylene]-1H-inden-1-one

2,3-Dihydro-5,6-dimethoxy-2-[(1-oxido-4-pyridinyl)methylene]-1H-inden-1-one


  • Catalogue No.:PA 04 40750

  • CAS :

    896134-06-8

  • Molecular Formula : C17H15NO4

  • Molecular Weight : 297.31

PA IPIPRS 71 14

Donepezil Hydrochloride (IPRS/71/14)


  • Catalogue No.:PA IPIPRS 71 14

  • CAS :

    NA

  • Molecular Formula :

  • Molecular Weight : NA

PA 04 40760

Dehydrodeoxy Donepezil Hydrochloride

Dehydrodeoxy Donepezil Hydrochloride


  • Catalogue No.:PA 04 40760

  • CAS :

    NA

  • Molecular Formula : C24H30ClNO2

  • Molecular Weight : 399.96

PA 04 40770

Donepezil Keto Acid Sodium Salt

Donepezil Keto Acid Sodium Salt


  • Catalogue No.:PA 04 40770

  • CAS :

    NA

  • Molecular Formula : C24H28NNaO5

  • Molecular Weight : 433.48

PA 04 40780

Donepezil Open-Ring Hydroxy Acid

Donepezil Open-Ring Hydroxy Acid


  • Catalogue No.:PA 04 40780

  • CAS :

    NA

  • Molecular Formula : C24H31NO5

  • Molecular Weight : 413.51

PA 04 40790

2-((1-Benzyl-2-hydroxypiperidin-4-yl)methyl)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one

2-((1-Benzyl-2-hydroxypiperidin-4-yl)methyl)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one


  • Catalogue No.:PA 04 40790

  • CAS :

    NA

  • Molecular Formula : C24H29NO4

  • Molecular Weight : 395.5

PA 04 40800

2-((1-Benzyl-3-hydroxypiperidin-4-yl)methyl)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one

2-((1-Benzyl-3-hydroxypiperidin-4-yl)methyl)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one


  • Catalogue No.:PA 04 40800

  • CAS :

    NA

  • Molecular Formula : C24H29NO4

  • Molecular Weight : 395.5

PA 04 40030

Donepezil - Impurity C

(2R)-2-[(S)-(1-Benzylpiperidin-4-yl)(hydroxy)methyl]-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one


  • Catalogue No.:PA 04 40030

  • CAS :

    NA

  • Molecular Formula : C24H29NO4

  • Molecular Weight : 395.50

PA 04 0391001

1-Benzyl-4-(5,6-dimethoxy-1-oxoindan-2-yl)methylene-1,2,3,4-tetrahydropyridine

1-Benzyl-4-(5,6-dimethoxy-1-oxoindan-2-yl)methylene-1,2,3,4-tetrahydropyridine


  • Catalogue No.:PA 04 0391001

  • CAS :

    1020661-51-1

  • Molecular Formula : C24H25NO3

  • Molecular Weight : 375.47

PA 04 0391002

3-Keto Donepezil

3-Keto Donepezil


  • Catalogue No.:PA 04 0391002

  • CAS :

    1023500-88-0

  • Molecular Formula : C24H27NO4

  • Molecular Weight : 393.48

PA 04 0391003

5,6-Dimethoxy-2-[(4-piperidyl)methyl]indane hydrochloride

5,6-Dimethoxy-2-[(4-piperidyl)methyl]indane hydrochloride


  • Catalogue No.:PA 04 0391003

  • CAS :

    1034439-43-4

  • Molecular Formula : C17H26ClNO2

  • Molecular Weight : 311.85