dorzolamide hydrochloride and its Impurities
A carbonic anhydrase inhibitor, Dorzolamide Hydrochloride is used for the treatment of glaucoma and ocular hypertension. It is administered as topical opthalmic form and decreases the aqueous humour production.. Reference standards of Dorzolamide Hydrochloride API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below
N-((4R,6S)-6-Methyl-7,7-dioxido-2-sulfamoyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-4-yl)acetamide
N-((4R,6S)-6-Methyl-7,7-dioxido-2-sulfamoyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-4-yl)acetamide
Catalogue No.:PAI 31 003006
CAS :
147128-79-8
Molecular Formula : C10H14N2O5S3
Molecular Weight : 338.41
(4R,6S)-4-((2-Methoxyethoxy)methoxy)-6-methyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide
(4R,6S)-4-((2-Methoxyethoxy)methoxy)-6-methyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide
Catalogue No.:PAI 31 003010
CAS :
NA
Molecular Formula : C12H19NO7S3
Molecular Weight : 385.46
(4R,6R)-4-(Ethylamino)-6-methyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide Maleate
(4R,6R)-4-(Ethylamino)-6-methyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide Maleate
Catalogue No.:PAI 31 003014
CAS :
NA
Molecular Formula : C14H20N2O8S3
Molecular Weight : 440.5
(4R,6R)-4-(Ethylamino)-6-methyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide
(4R,6R)-4-(Ethylamino)-6-methyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide
Catalogue No.:PAI 31 003015
CAS :
NA
Molecular Formula : C10H16N2O4S3
Molecular Weight : 324.43