dronedarone and its Impurities
Dronedarone is a Class antiarrhythmic drug that works to restore the normal sinus rhythm in patients with paroxysmal or persistent atrial fibrillation. Dronedarone is a related benzofuran compound to amiodarone but its chemical structure lacks iodine moieties which are associated with amiodarone-induced thyroid problems. Reference standards of Dronedarone API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below


Dronedarone Related Compound C ((5-Amino-2-butylbenzofuran-3-yl)(4-hydroxyphenyl)methanone) (1228563)
Dronedarone Related Compound C ((5-Amino-2-butylbenzofuran-3-yl)(4-hydroxyphenyl)methanone) (1228563)
Catalogue No.:PA USP1228563
CAS :
1278585-68-4
Molecular Formula : NA
Molecular Weight : NA


Dronedarone Related Compound B ((5-Amino-2-butylbenzofuran-3-yl){4-[3-(dibutylamino)propoxy]phenyl} (1228552)
Dronedarone Related Compound B ((5-Amino-2-butylbenzofuran-3-yl){4-[3-(dibutylamino)propoxy]phenyl} (1228552)
Catalogue No.:PA USP1228552
CAS :
1309476-91-2
Molecular Formula : NA
Molecular Weight : NA


Dronedarone Related Compound D ((2-Butyl-5-nitrobenzofuran-3-yl)(4-hydroxyphenyl)methanone) (1228574)
Dronedarone Related Compound D ((2-Butyl-5-nitrobenzofuran-3-yl)(4-hydroxyphenyl)methanone) (1228574)
Catalogue No.:PA USP1228574
CAS :
141645-16-1
Molecular Formula : NA
Molecular Weight : NA


Dronedarone Related Compound A (N-{2-Butyl-3-[4-(3-butylaminopropoxy)benzoyl]benzofuran-5-yl}methan (1228541)
Dronedarone Related Compound A (N-{2-Butyl-3-[4-(3-butylaminopropoxy)benzoyl]benzofuran-5-yl}methan (1228541)
Catalogue No.:PA USP1228541
CAS :
197431-02-0
Molecular Formula : NA
Molecular Weight : NA


(5-​Amino-​2-​butyl-​3-​benzofuranyl)​[4-​[3-​(butylamino)​propoxy]​phenyl]​methanone
(5-​Amino-​2-​butyl-​3-​benzofuranyl)​[4-​[3-​(butylamino)​propoxy]​phenyl]​methanone
Catalogue No.:PA 31 16540
CAS :
141626-26-8
Molecular Formula : C26H34N2O3
Molecular Weight : 422.56


N-Butyl-N-(3-(4-(2-butyl-5-(methylsulfonamido)benzofuran-3-carbonyl)phenoxy)propyl)-N-ethylbutan-1-aminium methanesulfonate
N-Butyl-N-(3-(4-(2-butyl-5-(methylsulfonamido)benzofuran-3-carbonyl)phenoxy)propyl)-N-ethylbutan-1-aminium methanesulfonate
Catalogue No.:PA 31 0301001
CAS :
NA
Molecular Formula : C34H52N2O8S2
Molecular Weight : 680.92