ebastine and its Impurities

Ebastine is a second generation H1 antihistamine drug, which does not cross the blood brain barrier and causes low drowsiness. It is used for the treatment of rhinitis and urticaria. Reference standards of Ebastine API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

Displaying 36 results for ebastine Impurities
PA 05 01000

Ebastine

Ebastine

  • Catalogue No.:PA 05 01000

  • CAS :

    90729-43-4

  • Molecular Formula : C32H39NO2

  • Molecular Weight : 469.66

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PA 05 01010

Ebastine - Impurity A

Benzhydrol

  • Catalogue No.:PA 05 01010

  • CAS :

    91-01-0

  • Molecular Formula : C13H12O

  • Molecular Weight : 184.23

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PA 05 01030

Ebastine - Impurity C (Hydrochloride Salt)

4-(Diphenyl- methoxy)piperidine Hydrochloride

  • Catalogue No.:PA 05 01030

  • CAS :

    65214-86-0

  • Molecular Formula : C18H22ClNO

  • Molecular Weight : 303.83

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PA 05 01040

Ebastine - Impurity D

1-[3-(4-tert-Butylbenzoyl)propyl]-4-hydroxypiperidine

  • Catalogue No.:PA 05 01040

  • CAS :

    97928-18-2

  • Molecular Formula : C19H29NO2

  • Molecular Weight : 303.44

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PA 05 01050

Ebastine - Impurity E

1-[4-(1,1-Dimethylpropyl)phenyl]-4-[4-(diphenylmethoxy)-piperidin-1-yl]butan-1-one Hydrogen Fumarate

  • Catalogue No.:PA 05 01050

  • CAS :

    2734346-74-6

  • Molecular Formula : C37H45NO6

  • Molecular Weight : 599.76

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PA 05 01060

Ebastine - Impurity F

1-[4-(1,1-dimethylethyl)phenyl]-4-[cis-4-(diphenylmethoxy)-1-oxidopiperidin-1-yl]butan-1-one

  • Catalogue No.:PA 05 01060

  • CAS :

    1429071-63-5

  • Molecular Formula : C32H39NO3

  • Molecular Weight : 485.67

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PA 05 01070

Ebastine - Impurity G

1-[4-(1,1-dimethylethyl)phenyl]-4-[trans-4-(diphenylmethoxy)-1-oxidopiperidin-1-yl]butan-1-one

  • Catalogue No.:PA 05 01070

  • CAS :

    1429071-65-7

  • Molecular Formula : C32H39NO3

  • Molecular Weight : 485.67

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PA 05 01510

Ebastine - Impurity B

4-tert-Butylacetophenone

  • Catalogue No.:PA 05 01510

  • CAS :

    943-27-1

  • Molecular Formula : C12H16O

  • Molecular Weight : 176.25

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PA 05 01520

Carebastine Methyl Ester

Carebastine Methyl Ester

  • Catalogue No.:PA 05 01520

  • CAS :

    189064-48-0

  • Molecular Formula : C33H39NO4

  • Molecular Weight : 513.67

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PA 05 01530

4-(Cyclopropylcarbonyl)-α,α-dimethylbenzeneacetic Acid Methyl Ester

4-(Cyclopropylcarbonyl)-α,α-dimethylbenzeneacetic Acid Methyl Ester

  • Catalogue No.:PA 05 01530

  • CAS :

    880088-78-8

  • Molecular Formula : C15H18O3

  • Molecular Weight : 246.3

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PA 05 01540

Ebastine N-Oxide

Ebastine N-Oxide

  • Catalogue No.:PA 05 01540

  • CAS :

    1256285-71-8

  • Molecular Formula : C32H39NO3

  • Molecular Weight : 485.66

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PA 05 01550

4-[(2-Vinyl]-1-enthyne)-α,α-dimethyl-benzeneacetic Acid Methyl Ester

4-[(2-Vinyl]-1-enthyne)-α,α-dimethyl-benzeneacetic Acid Methyl Ester

  • Catalogue No.:PA 05 01550

  • CAS :

    1159977-63-5

  • Molecular Formula : C15H16O2

  • Molecular Weight : 228.29

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PA STI 027090

Desalkyl Ebastine-d5

Desalkyl Ebastine-d5

  • Catalogue No.:PA STI 027090

  • CAS :

    1189424-36-9

  • Molecular Formula : C18H16D5NO

  • Molecular Weight : 272.40

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PA STI 036720

Ebastine-d5

Ebastine-d5

  • Catalogue No.:PA STI 036720

  • CAS :

    1216953-13-7

  • Molecular Formula : C32H34D5NO2

  • Molecular Weight : 474.69

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PA STI 036730

Ebastine-d5 N-Oxide

Ebastine-d5 N-Oxide

  • Catalogue No.:PA STI 036730

  • CAS :

    NA

  • Molecular Formula : C32H34D5NO3

  • Molecular Weight : 490.69

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PA STI 048260

Hydroxy Ebastine-d5

Hydroxy Ebastine-d5

  • Catalogue No.:PA STI 048260

  • CAS :

    1189954-07-1

  • Molecular Formula : C32H34D5NO3

  • Molecular Weight : 490.69

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PA USP1231230

Ebastine Related Compound C (4-(diphenylmethoxy)piperidine hydrochloride) (1231230)

Ebastine Related Compound C (4-(diphenylmethoxy)piperidine hydrochloride) (1231230)

  • Catalogue No.:PA USP1231230

  • CAS :

    65214-86-0

  • Molecular Formula : NA

  • Molecular Weight : NA

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PA USP1231207

Ebastine (1231207)

Ebastine (1231207)

  • Catalogue No.:PA USP1231207

  • CAS :

    90729-43-4

  • Molecular Formula : NA

  • Molecular Weight : NA

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PA USP1231246

Ebastine Related Compound D (1-[4-(1,1-Dimethylethyl)phenyl]-4-(4-hydroxypiperidin-1-yl)butan-1-one (1231246)

Ebastine Related Compound D (1-[4-(1,1-Dimethylethyl)phenyl]-4-(4-hydroxypiperidin-1-yl)butan-1-one (1231246)

  • Catalogue No.:PA USP1231246

  • CAS :

    97928-18-2

  • Molecular Formula : NA

  • Molecular Weight : NA

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PA USP1231251

Ebastine Related Compound E (1-[4-(1,1-Dimethylpropyl)phenyl]-4-[4-(diphenylmethoxy)piperidin-1-yl] (1231251)

Ebastine Related Compound E (1-[4-(1,1-Dimethylpropyl)phenyl]-4-[4-(diphenylmethoxy)piperidin-1-yl] (1231251)

  • Catalogue No.:PA USP1231251

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

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PA USP1231262

Ebastine Related Compound F (1-[4-(1,1-dimethylethyl)phenyl]-4-[cis-4-(diphenylmethoxy)-1-oxidopipe (1231262)

Ebastine Related Compound F (1-[4-(1,1-dimethylethyl)phenyl]-4-[cis-4-(diphenylmethoxy)-1-oxidopipe (1231262)

  • Catalogue No.:PA USP1231262

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

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PA USP1231273

Ebastine Related Compound G (1-[4-(1,1-dimethylethyl)phenyl]-4-[trans-4-(diphenylmethoxy)-1-oxidopi (1231273)

Ebastine Related Compound G (1-[4-(1,1-dimethylethyl)phenyl]-4-[trans-4-(diphenylmethoxy)-1-oxidopi (1231273)

  • Catalogue No.:PA USP1231273

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

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PA EPY0000249

Ebastine - reference spectrum (Y0000249)

Ebastine - reference spectrum (Y0000249)

  • Catalogue No.:PA EPY0000249

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

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PA EPY0000247

Ebastine impurity C (Y0000247)

Ebastine impurity C (Y0000247)

  • Catalogue No.:PA EPY0000247

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

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PA EPY0000248

Ebastine impurity D (Y0000248)

Ebastine impurity D (Y0000248)

  • Catalogue No.:PA EPY0000248

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

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PA IPIPRS 64 13

Ebastine (IPRS/64/13)-from IPC

  • Catalogue No.:PA IPIPRS 64 13

  • CAS :

    NA

  • Molecular Formula :

  • Molecular Weight : NA

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PA 05 01080

Ebastine - Impurity H

bis(Diphenylmethyl) Ether

  • Catalogue No.:PA 05 01080

  • CAS :

    574-42-5

  • Molecular Formula : C26H22O

  • Molecular Weight : 350.46

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PA 05 0011000

Ebastine - Impurity C (Freebase)

4-(Diphenylmethoxy)piperidine

  • Catalogue No.:PA 05 0011000

  • CAS :

    58258-01-8

  • Molecular Formula : C18H21NO

  • Molecular Weight : 267.37

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PA 05 0011001

Hydroxy Ebastine

Hydroxy Ebastine

  • Catalogue No.:PA 05 0011001

  • CAS :

    210686-41-2

  • Molecular Formula : C32H39NO3

  • Molecular Weight : 485.67

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PA 05 0011002

Carebastine

Carebastine

  • Catalogue No.:PA 05 0011002

  • CAS :

    90729-42-3

  • Molecular Formula : C32H37NO4

  • Molecular Weight : 499.65

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PA IMP 02 19

Ebastine Impurity C (IMP/02/19) - from IPC

Ebastine Impurity C (IMP/02/19) - from IPC

  • Catalogue No.:PA IMP 02 19

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

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PA IMP 26 18

Ebastine Impurity D (IMP/26/18) - from IPC

Ebastine Impurity D (IMP/26/18) - from IPC

  • Catalogue No.:PA IMP 26 18

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

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PA IPRSE002

Ebastine (IPRSE002)

Ebastine (IPRSE002)

  • Catalogue No.:PA IPRSE002

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

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PA 05 0011003

(1R,2R)-2-(4-(Benzhydryloxy)piperidin-1-yl)-1-(4-(tert-butyl)phenyl)-2-methylcyclopropan-1-ol

(1R,2R)-2-(4-(Benzhydryloxy)piperidin-1-yl)-1-(4-(tert-butyl)phenyl)-2-methylcyclopropan-1-ol

  • Catalogue No.:PA 05 0011003

  • CAS :

    1661001-35-9

  • Molecular Formula : C32H39NO2

  • Molecular Weight : 469.67

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PA 05 0011004

4-(Benzhydryloxy)-1-nitrosopiperidine

4-(Benzhydryloxy)-1-nitrosopiperidine

  • Catalogue No.:PA 05 0011004

  • CAS :

    NA

  • Molecular Formula : C18H20N2O2

  • Molecular Weight : 296.37

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PA 05 0011005

Mixture of Ebastine Impurity F and Impurity G

Mixture of Ebastine Impurity F and Impurity G

  • Catalogue No.:PA 05 0011005

  • CAS :

    NA

  • Molecular Formula : C32H39NO3

  • Molecular Weight : 485.67

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CPHI INDIA- 28, 30 November