Efinaconazole acts as a 14α-demethylase inhibitor. which indicated in the treatment of fungal infection of the nail, known as onychomycosis.. Reference standards of Efinaconazole API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below
Efinaconazole
Catalogue No.:PA 05 79000
CAS :
Molecular Formula : C18H22F2N4O
Molecular Weight : 348.39
ent-Efinaconazole
Catalogue No.:PA 05 79510
(2R,3R)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butane-2,3-diol
Catalogue No.:PA 05 79520
Molecular Formula : C12H13F2N3O2
Molecular Weight : 269.25
(2S,3S)-2-(2,4-Difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butane-2,3-diol
Catalogue No.:PA 05 79530
(2R,3S)-2-(2,4-Difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butane-2,3-diol
Catalogue No.:PA 05 79540
(2S,3R)-2-(2,4-Difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butane-2,3-diol
Catalogue No.:PA 05 79550
(2R,3S)-Efinaconazole
Catalogue No.:PA 05 79560
(2S,3R)-Efinaconazole
Catalogue No.:PA 05 79570
Ethyl 1-benzoylpiperidine-4-carboxylate
Catalogue No.:PA 05 79580
Molecular Formula : C15H19NO3
Molecular Weight : 261.32
[4-(Hydroxymethyl)piperidin-1-yl]-phenylmethanone
Catalogue No.:PA 05 79590
Molecular Formula : C13H17NO2
Molecular Weight : 219.28
(4-(Chloromethyl)piperidin-1-yl)(phenyl)methanone
Catalogue No.:PA 05 79600
Molecular Formula : C13H16ClNO
Molecular Weight : 237.73
(4-Methylenepiperidin-1-yl)(phenyl)methanone
Catalogue No.:PA 05 79610
Molecular Formula : C13H15NO
Molecular Weight : 201.26
4-Methylenepiperidine
Catalogue No.:PA 05 79620
Molecular Formula : C6H11N
Molecular Weight : 97.16
(2R)-1-(2,4-Difluorophenyl)-2-(tetrahydro-2H-pyran-2-yloxy)propan-1-one
Catalogue No.:PA 05 79630
Molecular Formula : C14H16F2O3
Molecular Weight : 270.27
2-((R)-1-((R)-2-(2,4-Difluorophenyl)oxiran-2-yl)ethoxy)tetrahydro-2H-pyran
Catalogue No.:PA 05 79640
Molecular Formula : C15H18F2O3
Molecular Weight : 284.3
(2R,3R)-2-(2,4-Difluorophenyl)-3-((tetrahydro-2H-pyran-2-yl)oxy)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol
Catalogue No.:PA 05 79650
Molecular Formula : C17H21F2N3O3
Molecular Weight : 353.36
1,2,4-Triazole
Catalogue No.:PA 05 79660
Molecular Formula : C2H3N3
Molecular Weight : 69.07
(2R,3R)-2-(2,4-Difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-2,3-butanediol Methanesulfonate
Catalogue No.:PA 05 79670
Molecular Formula : C13H17F2N3O5S
Molecular Weight : 365.35
4-Methylenepiperidine Hydrochloride
Catalogue No.:PA 05 79680
Molecular Formula : C6H12ClN
Molecular Weight : 133.6
(2S,3S)-2-(2,4-Difluorophenyl)-3-methyl-2-[(1H-1,2,4-triazol-1-yl)methyl]oxirane
Catalogue No.:PA 05 79690
Molecular Formula : C12H11F2N3O
Molecular Weight : 251.23
(2R,3R)-2-(2,4-Difluorophenyl)-3-methyl-2-[(1H-1,2,4-triazol-1-yl)methyl]oxirane
Catalogue No.:PA 05 79700
(2S,3R)-2-(2,4-Difluorophenyl)-3-methyl-2-[(1H-1,2,4-triazol-1-yl)methyl]oxirane
Catalogue No.:PA 05 79710
Morpholine, 4-[(2R)-1-oxo-2-[(tetrahydro-2H-pyran-2-yl)oxy]propyl]-;
Catalogue No.:PA 05 79720
Molecular Formula : C12H21NO4
Molecular Weight : 243.3
1-((R)-1-((R)-8-((1H-1,2,4-Triazol-1-yl)methyl)-4-fluoro-7-oxabicyclo[4.2.0]octa-1(6),2,4-trien-8-yl)ethyl)-4-methylenepiperidine
Catalogue No.:PA 05 79730
Molecular Formula : C18H21FN4O
Molecular Weight : 328.38
(2R,3R)-2-(2,4-Difluorophenyl)-1-(4H-1,2,4-triazol-4-yl)butane-2,3-diol
Catalogue No.:PA 05 79740
Efinaconazole(2R,3R)Regiamer
Catalogue No.:PA 05 79750
Molecular Weight : 348.4
(2R,3R)-2-(2-Fluoro-4-(4-methylenepiperidin-1-yl)phenyl)-3-(4-methylenepiperidin-1-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol
Catalogue No.:PA 05 79760
Molecular Formula : C24H32FN5O
Molecular Weight : 425.55
(2R,3R)-3-((1H-1,2,4-Triazol-1-yl)methyl)-6-fluoro-3-hydroxy-2-methyl-4'-methylenespiro[indoline-1,1'-piperidin]-1-ium Fluoride
Catalogue No.:PA 05 79770
(2R,3R)-3-(2,4-Difluorophenyl)-3,4-epoxybutan-2-ol
Catalogue No.:PA 05 79780
Molecular Formula : C10H10F2O2
Molecular Weight : 200.18
(S,E)-3-(2,4-Difluorophenyl)-4-(1H-1,2,4-triazol-1-yl)but-3-en-2-ol
Catalogue No.:PA 05 79790
Molecular Weight : 251.24
(2S)-1-(2,4-Difluorophenyl)-2-((tetrahydro-2H-pyran-2-yl)oxy)propan-1-one
Catalogue No.:PA 05 79800
Molecular Weight : 270.28
(2R,3R)-2-(2,4-Difluorophenyl)-3-(3-methylenepiperidin-1-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol
Catalogue No.:PA 05 79810
2-((1-((S)-2-(2,4-Difluorophenyl)oxiran-2-yl)vinyl)oxy)tetrahydro-2H-pyran
Catalogue No.:PA 05 79820
Molecular Formula : C15H16F2O3
Molecular Weight : 282.29
Des-4-methylenepiperidine Efinaconazole
Catalogue No.:PA 05 0791000
(2S,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanenitrile
Catalogue No.:PA 05 0791001
Molecular Formula : C13H12F2N4O
Molecular Weight : 278.26
(2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanamide
Catalogue No.:PA 05 0791002
Molecular Formula : C13H14F2N4O2
Molecular Weight : 296.28
1-(((2R,3S)-2-(2,4-Difluorophenyl)-3-methyloxiran-2-yl)methyl)-1H-1,2,4-triazole
Catalogue No.:PA 05 0791003
Efinaconazole 4-Desfluoro Impurity
Catalogue No.:PA 05 0791004
Molecular Formula : C18H23FN4O
Molecular Weight : 330.41
(2R,3R)-2-Phenyl-1-(1H-1,2,4-triazol-1-yl)butane-2,3-diol
Catalogue No.:PA 05 0791005
Molecular Formula : C12H15N3O2
Molecular Weight : 233.27
(2S,3S)-3-(2,5-Difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanenitrile
Catalogue No.:PA 05 0791006
(2R,3R)-2-(4-Fluorophenyl)-3-(4-methylenepiperidin-1-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol
Catalogue No.:PA 05 0791007
Efinaconazole-N-oxide
Catalogue No.:PA 05 0791008
Molecular Formula : C18H22F2N4O2
Molecular Weight : 364.4
(R)-1-(2,4-Difluorophenyl)-2-hydroxypropan-1-one
Catalogue No.:PA 05 0791009
Molecular Formula : C9H8F2O2
Molecular Weight : 186.16
1-(4-Bromo-3-fluorophenyl)-1H-1,2,4-triazole
Catalogue No.:PA 05 0791010
Molecular Formula : C8H5BrFN3
Molecular Weight : 242.05
1-(2-Bromo-5-fluorophenyl)-1H-1,2,4-triazole
Catalogue No.:PA 05 0791011
2-(2,4-Difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butane-2,3-diol
Catalogue No.:PA 05 0791012
(2R,3R)-3-(2,4-difluorophenyl)-3-hydroxy-4-(1H-1,2,4-triazol-1-yl)butan-2-yl methanesulfonate
Catalogue No.:PA 05 0791013
Molecular Formula : C13H15F2N3O4S
Molecular Weight : 347.34
(2R,3R)-2-(2,4-Difluorophenyl)-3-(4-(hydroxymethyl)piperidin-1-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol
Catalogue No.:PA 05 0791014
Molecular Formula : C18H24F2N4O2
Molecular Weight : 366.41
(2R,3R)-2-(4-Fluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butane-2,3-diol
Catalogue No.:PA 05 0791015
Molecular Formula : C12H14FN3O2
Molecular Weight : 251.26
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