Elexacaftor and its Impurities
Elexacaftor is a small molecule CFTR corrector used in combination with tezacaftor and ivacaftor for the treatment of cystic fibrosis patients with one F508del-CFTR mutation. Reference standards of Elexacaftor API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
2-Chloro-N-((1,3-dimethyl-1H-pyrazol-4-yl)sulfonyl)-6-(3-(3,3,3-trifluoro-2,2-dimethylpropoxy)-1H-pyrazol-1-yl)nicotinamide
2-Chloro-N-((1,3-dimethyl-1H-pyrazol-4-yl)sulfonyl)-6-(3-(3,3,3-trifluoro-2,2-dimethylpropoxy)-1H-pyrazol-1-yl)nicotinamide
Catalogue No.:PA 05 1861001
CAS :
2229861-18-9
Molecular Formula : C19H20ClF3N6O4S
Molecular Weight : 520.91
