Entacapone-Impurities | Pharmaffiliates

entacapone and its Impurities

A selective and reversible inhibitor of enzyme catechol-O-methyltransferase (COMT), it is used for the treatment of Parkinson's disease. It is used in addition to levodopa. Reference standards of Entacapone API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

Displaying 27 results for entacapone Impurities
PA 05 06000

Entacapone - API

Entacapone


  • Catalogue No.:PA 05 06000

  • CAS :

    130929-57-6

  • Molecular Formula : C14H15N3O5

  • Molecular Weight : 305.29

PA 05 06010

Entacapone - Impurity A

(2Z)-2-Cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethyl-2-propenamide


  • Catalogue No.:PA 05 06010

  • CAS :

    145195-63-7

  • Molecular Formula : C14H15N3O5

  • Molecular Weight : 305.29

PA 05 06020

Entacapone - Impurity B

Ethyl (2E)-2-Cyano-3-(3,4-dihydroxy-5-nitrophenyl)prop-2-enoate


  • Catalogue No.:PA 05 06020

  • CAS :

    1215039-66-9

  • Molecular Formula : C12H10N2O6

  • Molecular Weight : 278.22

PA 05 06030

Entacapone - Impurity C

3,4-Dihydroxy-5-nitrobenzaldehyde


  • Catalogue No.:PA 05 06030

  • CAS :

    116313-85-0

  • Molecular Formula : C7H5NO5

  • Molecular Weight : 183.12

PA 05 06040

Entacapone - Impurity D

(2E)-2-Cyano-3-(3-ethoxy-4-hydroxy-5-nitrophenyl)-N,N-diethyl-2-propenamide


  • Catalogue No.:PA 05 06040

  • CAS :

    857629-79-9

  • Molecular Formula : C16H19N3O5

  • Molecular Weight : 333.34

PA 05 06050

Entacapone - Impurity E

3,5-Dinitrobenzene-1,2-diol


  • Catalogue No.:PA 05 06050

  • CAS :

    7659-29-2

  • Molecular Formula : C6H4N2O6

  • Molecular Weight : 200.11

PA 05 06060

Entacapone - Impurity F

(2E)-2-Cyano-3-(3,4-dihydroxy-5-nitrophenyl)prop-2-enoic acid


  • Catalogue No.:PA 05 06060

  • CAS :

    160391-70-8

  • Molecular Formula : C10H6N2O6

  • Molecular Weight : 250.16

PA 05 06070

Entacapone - Impurity G

(2E)-2-Cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N-methyl-prop-2-enamide


  • Catalogue No.:PA 05 06070

  • CAS :

    1364322-41-7

  • Molecular Formula : C11H9N3O5

  • Molecular Weight : 263.21

PA 05 06080

Entacapone - Impurity H

(2E)-3-(3,4-Dihydroxy-5-nitrophenyl)-2-(piperidin-1-ylcarbonyl)prop-2-ennitrile


  • Catalogue No.:PA 05 06080

  • CAS :

    1150310-15-8

  • Molecular Formula : C15H15N3O5

  • Molecular Weight : 317.30

PA 05 06090

Entacapone - Impurity I

Propyl (2E)-2-Cyano-3-(3,4-dihydroxy-5-nitrophenyl)prop-2-enoate


  • Catalogue No.:PA 05 06090

  • CAS :

    1364322-42-8

  • Molecular Formula : C13H12N2O6

  • Molecular Weight : 292.24

PA 05 06510

(E)-2-Cyano-3-(3,4-dihydroxy-2-nitrophenyl)-N,N-diethylacrylamide

(E)-2-Cyano-3-(3,4-dihydroxy-2-nitrophenyl)-N,N-diethylacrylamide


  • Catalogue No.:PA 05 06510

  • CAS :

    NA

  • Molecular Formula : C14H15N3O5

  • Molecular Weight : 305.29

PA 05 06520

Entacapone Vanillin Dimer

Entacapone Vanillin Dimer


  • Catalogue No.:PA 05 06520

  • CAS :

    2518048-68-3

  • Molecular Formula : C21H28N4O4

  • Molecular Weight : 400.47

PA 05 06530

5-Nitrovanillin Dimer Impurity

5-Nitrovanillin Dimer Impurity


  • Catalogue No.:PA 05 06530

  • CAS :

    2514697-83-5

  • Molecular Formula : C22H29N5O6

  • Molecular Weight : 459.5

PA STI 037060

cis-Entacapone-d10

cis-Entacapone-d10


  • Catalogue No.:PA STI 037060

  • CAS :

    1185241-19-3

  • Molecular Formula : C14H5D10N3O5

  • Molecular Weight : 315.35

PA STI 037070

E-Entacapone-d10

E-Entacapone-d10


  • Catalogue No.:PA STI 037070

  • CAS :

    NA

  • Molecular Formula : C14H5D10N3O5

  • Molecular Weight : 315.35

PA EPY0001249

Entacapone (Y0001249)

Entacapone (Y0001249)


  • Catalogue No.:PA EPY0001249

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

PA EPY0001250

Entacapone impurity A (Y0001250)

Entacapone impurity A (Y0001250)


  • Catalogue No.:PA EPY0001250

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

PA USP1235933

Entacapone (1235933)

Entacapone (1235933)


  • Catalogue No.:PA USP1235933

  • CAS :

    130929-57-6

  • Molecular Formula : NA

  • Molecular Weight : NA

PA USP1235944

Entacapone Related Compound A ((Z)-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethylacrylamide) (1235944)

Entacapone Related Compound A ((Z)-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethylacrylamide) (1235944)


  • Catalogue No.:PA USP1235944

  • CAS :

    145195-63-7

  • Molecular Formula : NA

  • Molecular Weight : NA

PA IPIPRS 71 13

Entacapone (IPRS/71/13)-from IPC


  • Catalogue No.:PA IPIPRS 71 13

  • CAS :

    NA

  • Molecular Formula :

  • Molecular Weight : NA

PA 05 06540

2-Cyano-3-(3,4-dihydroxy-5-nitrophenyl)acrylamide

2-Cyano-3-(3,4-dihydroxy-5-nitrophenyl)acrylamide


  • Catalogue No.:PA 05 06540

  • CAS :

    158693-01-7

  • Molecular Formula : C10H7N3O5

  • Molecular Weight : 249.18

PA 05 0061000

Entacapone 3-o-glucuronide

Entacapone 3-o-glucuronide


  • Catalogue No.:PA 05 0061000

  • CAS :

    158069-75-1

  • Molecular Formula : C20H23N3O11

  • Molecular Weight : 481.41

PA 05 0061001

3,4-Dihydroxy-5-nitrobenzoic acid

3,4-Dihydroxy-5-nitrobenzoic acid


  • Catalogue No.:PA 05 0061001

  • CAS :

    84211-30-3

  • Molecular Formula : C7H5NO6

  • Molecular Weight : 199.12

PA 05 0061002

(E)-2-Cyano-3-(4-hydroxy-3-methoxy-5-nitrophenyl)acrylic acid

(E)-2-Cyano-3-(4-hydroxy-3-methoxy-5-nitrophenyl)acrylic acid


  • Catalogue No.:PA 05 0061002

  • CAS :

    1202160-40-4

  • Molecular Formula : C11H8N2O6

  • Molecular Weight : 264.19

PA 05 0061003

(E)-3-O-Methyl Entacapone

(E)-3-O-Methyl Entacapone


  • Catalogue No.:PA 05 0061003

  • CAS :

    857629-78-8

  • Molecular Formula : C15H17N3O5

  • Molecular Weight : 319.32

PA 05 0061004

(E)-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N-ethylacrylamide

(E)-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N-ethylacrylamide


  • Catalogue No.:PA 05 0061004

  • CAS :

    150995-46-3

  • Molecular Formula : C12H11N3O5

  • Molecular Weight : 277.24

PA 05 0061005

(E/Z)-3-O-Methyl Entacapone

(E/Z)-3-O-Methyl Entacapone


  • Catalogue No.:PA 05 0061005

  • CAS :

    146698-91-1

  • Molecular Formula : C15H17N3O5

  • Molecular Weight : 319.32