Etrasimod and its Impurities
Etrasimod, sold under the brand name Velsipity, it is an S1P receptors modulator used to treat moderate to severely active ulcerative colitis in adults. Reference standards of Etrasimod API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
7-((4-Cyclopentyl-3-(trifluoromethyl)benzyl)oxy)-5a-hydroxy-3,3a,4,5,5a,10-hexahydro-2H-furo[2',3':1,5]cyclopenta[1,2-b]indol-2-one
7-((4-Cyclopentyl-3-(trifluoromethyl)benzyl)oxy)-5a-hydroxy-3,3a,4,5,5a,10-hexahydro-2H-furo[2',3':1,5]cyclopenta[1,2-b]indol-2-one
Catalogue No.:PA 05 2191000
CAS :
NA
Molecular Formula : C26H26F3NO4
Molecular Weight : 473.49
(R)-2-(7-((4-cyclopentyl-3-(trifluoromethyl)benzyl)oxy)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)-N-methylacetamide
(R)-2-(7-((4-cyclopentyl-3-(trifluoromethyl)benzyl)oxy)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)-N-methylacetamide
Catalogue No.:PA 05 2191001
CAS :
2863532-89-0
Molecular Formula : C27H29F3N2O2
Molecular Weight : 470.54
Ethyl 2-(7-((4-cyclopentyl-3-(trifluoromethyl)benzyl)oxy)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetate
Ethyl 2-(7-((4-cyclopentyl-3-(trifluoromethyl)benzyl)oxy)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetate
Catalogue No.:PA 05 2191002
CAS :
1206124-34-6
Molecular Formula : C28H30F3NO3
Molecular Weight : 485.55
(R)-2-(7-((4-Cyclopentyl-3-(trifluoromethyl)benzyl)oxy)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)-N,N-dimethylacetamide
(R)-2-(7-((4-Cyclopentyl-3-(trifluoromethyl)benzyl)oxy)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)-N,N-dimethylacetamide
Catalogue No.:PA 05 2191003
CAS :
NA
Molecular Formula : C28H31F3N2O2
Molecular Weight : 484.56
2-(8-((4-Cyclopentyl-3-(trifluoromethyl)benzyl)oxy)-2,6-dioxo-1,2,3,4,5,6-hexahydrobenzo[b]azocin-3-yl)acetic Acid
2-(8-((4-Cyclopentyl-3-(trifluoromethyl)benzyl)oxy)-2,6-dioxo-1,2,3,4,5,6-hexahydrobenzo[b]azocin-3-yl)acetic Acid
Catalogue No.:PA 05 2191004
CAS :
NA
Molecular Formula : C26H26F3NO5
Molecular Weight : 489.49
