exemestane and its Impurities

Exemestane is used in the adjuvant treatment of hormonally-responsive breast cancer in postmenopausal women. It irreversibly binds to the active site of the enzyme resulting in permanent inhibition. It is an oral steroidal aromatase inhibitor.. Reference standards of Exemestane API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below

Displaying 53 results for exemestane Impurities
Drug Reference Standards & Impurity Synthesis in India
PA 05 54000

Exemestane

Exemestane

  • Catalogue No.:PA 05 54000

  • CAS :

    107868-30-4

  • Molecular Formula : C20H24O2

  • Molecular Weight : 296.40

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PA 05 54040

Exemestane - Impurity D

Androsta-1,4-diene-3,17-dione

  • Catalogue No.:PA 05 54040

  • CAS :

    897-06-3

  • Molecular Formula : C19H24O2

  • Molecular Weight : 284.39

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PA 05 54050

Exemestane - Impurity E

6-Methylideneandrost-4-ene-3,17-dione

  • Catalogue No.:PA 05 54050

  • CAS :

    19457-55-7

  • Molecular Formula : C20H26O2

  • Molecular Weight : 298.42

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PA 05 54060

Exemestane - Impurity F

6-Oxo Boldione

  • Catalogue No.:PA 05 54060

  • CAS :

    72648-46-5

  • Molecular Formula : C19H22O3

  • Molecular Weight : 298.38

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PA 05 54510

Exemestane - Impurity H

(17β)-17-Hydroxy-6-methylideneandrosta-1,4-dien-3-one

  • Catalogue No.:PA 05 54510

  • CAS :

    122370-91-6

  • Molecular Formula : C20H26O2

  • Molecular Weight : 298.42

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PA 05 54520

Exemestane α-Spirooxirane

Exemestane α-Spirooxirane

  • Catalogue No.:PA 05 54520

  • CAS :

    152764-24-4

  • Molecular Formula : C20H24O3

  • Molecular Weight : 312.4

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PA 05 54530

Exemestane β-Spirooxirane

Exemestane β-Spirooxirane

  • Catalogue No.:PA 05 54530

  • CAS :

    152764-31-3

  • Molecular Formula : C20H24O3

  • Molecular Weight : 312.4

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PA 05 54540

1,2-α-Epoxy Exemestane

1,2-α-Epoxy Exemestane

  • Catalogue No.:PA 05 54540

  • CAS :

    159354-61-7

  • Molecular Formula : C20H24O3

  • Molecular Weight : 312.4

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PA 05 54550

Exemestane 17-α Isomer

Exemestane 17-α Isomer

  • Catalogue No.:PA 05 54550

  • CAS :

    NA

  • Molecular Formula : C20H24O3

  • Molecular Weight : 312.4

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PA 05 54560

Exemestane 17-β Isomer

Exemestane 17-β Isomer

  • Catalogue No.:PA 05 54560

  • CAS :

    NA

  • Molecular Formula : C20H24O3

  • Molecular Weight : 312.4

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PA 05 54570

6α-(Methoxymethyl)androsta-1,4-dien-3,17-dione

6α-(Methoxymethyl)androsta-1,4-dien-3,17-dione

  • Catalogue No.:PA 05 54570

  • CAS :

    881896-95-3

  • Molecular Formula : C21H28O3

  • Molecular Weight : 328.45

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PA 05 54580

(1,2-α),(6,2')-Diepoxy Exemestane

(1,2-α),(6,2')-Diepoxy Exemestane

  • Catalogue No.:PA 05 54580

  • CAS :

    NA

  • Molecular Formula : C20H24O4

  • Molecular Weight : 328.4

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PA 05 54590

4-Chloro Exemestane

4-Chloro Exemestane

  • Catalogue No.:PA 05 54590

  • CAS :

    107868-36-0

  • Molecular Formula : C20H23ClO2

  • Molecular Weight : 330.85

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Drug Reference Standards & Impurity Synthesis in India
PA 05 54600

Exemestane Diol Impurity

Exemestane Diol Impurity

  • Catalogue No.:PA 05 54600

  • CAS :

    184972-11-0

  • Molecular Formula : C20H26O4

  • Molecular Weight : 330.42

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Drug Reference Standards & Impurity Synthesis in India
PA STI 061390

6-Methyleneandrost-4-ene-3,17-dione-19-d3

6-Methyleneandrost-4-ene-3,17-dione-19-d3

  • Catalogue No.:PA STI 061390

  • CAS :

    NA

  • Molecular Formula : C20H23D3O2

  • Molecular Weight : 301.44

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PA STI 040460

Exemestane-19-d3

Exemestane-19-d3

  • Catalogue No.:PA STI 040460

  • CAS :

    NA

  • Molecular Formula : C20H21D3O2

  • Molecular Weight : 299.42

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PA STI 040461

Exemestane-13C, d2

Exemestane-13C, d2

  • Catalogue No.:PA STI 040461

  • CAS :

    NA

  • Molecular Formula : C1913CH22D2O2

  • Molecular Weight : 299.41

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PA STI 040462

Exemestane-d2

Exemestane-d2

  • Catalogue No.:PA STI 040462

  • CAS :

    NA

  • Molecular Formula : C20H22D2O2

  • Molecular Weight : 298.42

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PA STI 047740

6-Hydroxymethyl Exemestane-d3

6-Hydroxymethyl Exemestane-d3

  • Catalogue No.:PA STI 047740

  • CAS :

    NA

  • Molecular Formula : C20H21D3O3

  • Molecular Weight : 315.42

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PA STI 049020

17β-Hydroxy Exemestane-d3

17β-Hydroxy Exemestane-d3

  • Catalogue No.:PA STI 049020

  • CAS :

    NA

  • Molecular Formula : C20H23D3O2

  • Molecular Weight : 301.44

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PA STI 049030

17β-Hydroxy Exemestane-d3 17-O-β-D-Glucuronide

17β-Hydroxy Exemestane-d3 17-O-β-D-Glucuronide

  • Catalogue No.:PA STI 049030

  • CAS :

    NA

  • Molecular Formula : C26H31D3O8

  • Molecular Weight : 477.56

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PA STI 049040

17β-Hydroxy Exemestane-d3 17-O-β-D-Glucuronide 2,3,4-Triacetate Methyl Ester

17β-Hydroxy Exemestane-d3 17-O-β-D-Glucuronide 2,3,4-Triacetate Methyl Ester

  • Catalogue No.:PA STI 049040

  • CAS :

    NA

  • Molecular Formula : C33H39D3O11

  • Molecular Weight : 617.7

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Drug Reference Standards & Impurity Synthesis in India
PA 05 54610

(6aR,6bS,8aS,8bS,9aR,10aS,10bR)-6a,8a-Dimethyl-2-methylene-1,2,6a,6b,7,8,8a,8b,9a,10,10a,10b-dodecahydro-4H-naphtho[2',1':4,5]indeno[1,2-b]oxiren-4-one

(6aR,6bS,8aS,8bS,9aR,10aS,10bR)-6a,8a-Dimethyl-2-methylene-1,2,6a,6b,7,8,8a,8b,9a,10,10a,10b-dodecahydro-4H-naphtho[2',1':4,5]indeno[1,2-b]oxiren-4-one

  • Catalogue No.:PA 05 54610

  • CAS :

    NA

  • Molecular Formula : C20H24O2

  • Molecular Weight : 296.41

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PA EPY0001747

Exemestane (Y0001747)

Exemestane (Y0001747)

  • Catalogue No.:PA EPY0001747

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

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PA EPY0001756

Exemestane for system suitability (Y0001756)

Exemestane for system suitability (Y0001756)

  • Catalogue No.:PA EPY0001756

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

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Drug Reference Standards & Impurity Synthesis in India
PA USP1269050

Exemestane (1269050)

Exemestane (1269050)

  • Catalogue No.:PA USP1269050

  • CAS :

    107868-30-4

  • Molecular Formula : NA

  • Molecular Weight : NA

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Drug Reference Standards & Impurity Synthesis in India
PA USP1269061

Exemestane Related Compound A (6-Methyleneandrosta-4-ene-3,17-dione) (1269061)

Exemestane Related Compound A (6-Methyleneandrosta-4-ene-3,17-dione) (1269061)

  • Catalogue No.:PA USP1269061

  • CAS :

    19457-55-7

  • Molecular Formula : NA

  • Molecular Weight : NA

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Drug Reference Standards & Impurity Synthesis in India
PA USP1269072

Exemestane Related Compound B (6-hydroxymethylandrostra-1,4-diene-3,17-dione) (1269072)

Exemestane Related Compound B (6-hydroxymethylandrostra-1,4-diene-3,17-dione) (1269072)

  • Catalogue No.:PA USP1269072

  • CAS :

    184972-09-6

  • Molecular Formula : NA

  • Molecular Weight : NA

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PA USP1269094

Exemestane System Suitability Mixture (1269094)

Exemestane System Suitability Mixture (1269094)

  • Catalogue No.:PA USP1269094

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

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PA 05 54020

Exemestane - Impurity B

6-Hydroxymethylandrosta-1,4-diene-3,17-dione

  • Catalogue No.:PA 05 54020

  • CAS :

    184972-09-6

  • Molecular Formula : C20H26O3

  • Molecular Weight : 314.43

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PA 05 54620

Spiro[androsta-1,4-diene-6,2′-oxirane]-3,17-dione

Spiro[androsta-1,4-diene-6,2′-oxirane]-3,17-dione

  • Catalogue No.:PA 05 54620

  • CAS :

    184972-12-1

  • Molecular Formula : C20H24O3

  • Molecular Weight : 312.41

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PA 05 0540090

Exemestane - Impurity I

(17β)-6-Methylidene-3-oxoandrosta-1,4-dien-17-yl Formate

  • Catalogue No.:PA 05 0540090

  • CAS :

    NA

  • Molecular Formula : C21H26O3

  • Molecular Weight : 326.44

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PA 05 0541000

Exemestane System Suitability Mixture

Exemestane System Suitability Mixture

  • Catalogue No.:PA 05 0541000

  • CAS :

    NA

  • Molecular Formula : C20H24O2

  • Molecular Weight : 296.41

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PA 05 0541001

6β-Hydroxymethylandrosta-1,4-diene-3,17-dione

6β-Hydroxymethylandrosta-1,4-diene-3,17-dione

  • Catalogue No.:PA 05 0541001

  • CAS :

    121021-51-0

  • Molecular Formula : C20H26O3

  • Molecular Weight : 314.43

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PA 05 0540030

Exemestane - Impurity C

(8R,9S,10R,13S,14S)-10,13-Dimethyl-6,16-dimethylene-7,8,9,10,11,12,13,14,15,16-decahydro-3H-cyclopenta[a]phenanthrene-3,17(6H)-dione

  • Catalogue No.:PA 05 0540030

  • CAS :

    2130745-60-5

  • Molecular Formula : C21H24O2

  • Molecular Weight : 308.42

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PA 05 0541002

(8R,9S,13S,14S)-1-Hydroxy-4,13-dimethyl-6,7,8,9,11,12,13,14,15,16-decahydro-17H-cyclopenta[a]phenanthren-17-one

(8R,9S,13S,14S)-1-Hydroxy-4,13-dimethyl-6,7,8,9,11,12,13,14,15,16-decahydro-17H-cyclopenta[a]phenanthren-17-one

  • Catalogue No.:PA 05 0541002

  • CAS :

    4954-08-9

  • Molecular Formula : C19H24O2

  • Molecular Weight : 284.4

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PA 05 0541004

((8R,9S,10R,13S,14S)-10,13-Dimethyl-3,17-dioxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-6-yl)methyl methanesulfonate

((8R,9S,10R,13S,14S)-10,13-Dimethyl-3,17-dioxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-6-yl)methyl methanesulfonate

  • Catalogue No.:PA 05 0541004

  • CAS :

    861395-77-9

  • Molecular Formula : C21H28O5S

  • Molecular Weight : 392.51

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PA 05 0540100

Exemestane - Impurity J

(17β)-6-Methylidene-3-oxoandrosta-1,4-dien-17-yl Acetate

  • Catalogue No.:PA 05 0540100

  • CAS :

    1160599-91-6

  • Molecular Formula : C22H28O3

  • Molecular Weight : 340.46

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PA STI 089136

Exemestane D4

Exemestane D4

  • Catalogue No.:PA STI 089136

  • CAS :

    NA

  • Molecular Formula : C20H20D4O2

  • Molecular Weight : 300.43

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PA 05 0541005

Delta-1,6-methylene -17-hydroxyprogest

Delta-1,6-methylene -17-hydroxyprogest

  • Catalogue No.:PA 05 0541005

  • CAS :

    1204325-01-8

  • Molecular Formula : C22H28O3

  • Molecular Weight : 340.46

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PA 05 0541006

6-Hydroxymethyl Exemestane

6-Hydroxymethyl Exemestane

  • Catalogue No.:PA 05 0541006

  • CAS :

    152764-26-6

  • Molecular Formula : C20H24O3

  • Molecular Weight : 312.41

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PA 05 0541007

17-Beta-Hydroxy Exemestane Epoxide

17-Beta-Hydroxy Exemestane Epoxide

  • Catalogue No.:PA 05 0541007

  • CAS :

    1331732-05-8

  • Molecular Formula : C20H26O3

  • Molecular Weight : 314.43

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PA 05 0541008

(8R,9S,10R,13S,14S)-6-(Methoxymethyl)-10,13-dimethyl-7,8,9,10,11,12,13,14,15,16-decahydro-3H-cyclopenta[a]phenanthrene-3,17(6H)-dione

(8R,9S,10R,13S,14S)-6-(Methoxymethyl)-10,13-dimethyl-7,8,9,10,11,12,13,14,15,16-decahydro-3H-cyclopenta[a]phenanthrene-3,17(6H)-dione

  • Catalogue No.:PA 05 0541008

  • CAS :

    861398-01-8

  • Molecular Formula : C21H28O3

  • Molecular Weight : 328.45

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PA 05 0541009

16-Methyleneandrosta-1,4-diene-3,17-dione

16-Methyleneandrosta-1,4-diene-3,17-dione

  • Catalogue No.:PA 05 0541009

  • CAS :

    2467590-81-2

  • Molecular Formula : C20H24O2 

  • Molecular Weight : 296.41

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PA 05 0541010

Pregna-1,4-Diene-3-One, 17,20-Dihydroxy-6-Methylene

Pregna-1,4-Diene-3-One, 17,20-Dihydroxy-6-Methylene

  • Catalogue No.:PA 05 0541010

  • CAS :

    1204325-02-9

  • Molecular Formula : C22H30O3

  • Molecular Weight : 342.48

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PA 05 0541011

(8R,9S,10R,13S,14S)-10,13-Dimethyl-3,17-dioxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthrene-6-carbaldehyde

(8R,9S,10R,13S,14S)-10,13-Dimethyl-3,17-dioxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthrene-6-carbaldehyde

  • Catalogue No.:PA 05 0541011

  • CAS :

    NA

  • Molecular Formula : C20H24O3 

  • Molecular Weight : 312.41

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PA 05 0541012

(8R,9S,10R,13S,14S)-17-Hydroxy-10,13-dimethyl-3-oxo-8,9,10,11,12,13,14,15,16,17-decahydro-3H-cyclopenta[a]phenanthrene-6-carbaldehyde

(8R,9S,10R,13S,14S)-17-Hydroxy-10,13-dimethyl-3-oxo-8,9,10,11,12,13,14,15,16,17-decahydro-3H-cyclopenta[a]phenanthrene-6-carbaldehyde

  • Catalogue No.:PA 05 0541012

  • CAS :

    NA

  • Molecular Formula : C20H24O3 

  • Molecular Weight : 312.41

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PA 05 0541013

(8R,9S,10R,13S,14S)-3-Ethoxy-10,13-dimethyl-6-methylene-1,2,3,6,7,8,9,10,11,12,13,14,15,16-tetradecahydro-17H-cyclopenta[a]phenanthren-17-one

(8R,9S,10R,13S,14S)-3-Ethoxy-10,13-dimethyl-6-methylene-1,2,3,6,7,8,9,10,11,12,13,14,15,16-tetradecahydro-17H-cyclopenta[a]phenanthren-17-one

  • Catalogue No.:PA 05 0541013

  • CAS :

    NA

  • Molecular Formula : C22H32O2

  • Molecular Weight : 328.5

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PA 05 0541014

((6S,8R,9S,10R,13S,14S)-10,13-dimethyl-3,17-dioxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-6-yl)methyl methanesulfonate

((6S,8R,9S,10R,13S,14S)-10,13-dimethyl-3,17-dioxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-6-yl)methyl methanesulfonate

  • Catalogue No.:PA 05 0541014

  • CAS :

    NA

  • Molecular Formula : C21H28O5S

  • Molecular Weight : 392.51

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PA 05 0541015

(8R,9S,10R,13S,14S)-3-Hydroxy-6,10,13-trimethyl-1,2,7,8,9,10,11,12,13,14,15,16-dodecahydro-17H-cyclopenta[a]phenanthren-17-one

(8R,9S,10R,13S,14S)-3-Hydroxy-6,10,13-trimethyl-1,2,7,8,9,10,11,12,13,14,15,16-dodecahydro-17H-cyclopenta[a]phenanthren-17-one

  • Catalogue No.:PA 05 0541015

  • CAS :

    NA

  • Molecular Formula : C20H28O2

  • Molecular Weight : 300.44

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PA 05 0541016

(8R,9S,10R,13S,14S)-17-Hydroxy-10,13-dimethyl-6,16-dimethylene-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one

(8R,9S,10R,13S,14S)-17-Hydroxy-10,13-dimethyl-6,16-dimethylene-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one

  • Catalogue No.:PA 05 0541016

  • CAS :

    NA

  • Molecular Formula : C21H26O2

  • Molecular Weight : 310.44

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PA 05 0541017

((6R,8R,9S,10R,13S,14S)-10,13-Dimethyl-3,17-dioxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-6-yl)methyl methanesulfonate

((6R,8R,9S,10R,13S,14S)-10,13-Dimethyl-3,17-dioxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-6-yl)methyl methanesulfonate

  • Catalogue No.:PA 05 0541017

  • CAS :

    NA

  • Molecular Formula : C21H28O5S

  • Molecular Weight : 392.51

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PA 05 0541018

Mixture of 6alpha-Hydroxymethylandrosta-1,4-diene-3,17-dione and 6beta-Hydroxymethylandrosta-1,4-diene-3,17-dione

Mixture of 6alpha-Hydroxymethylandrosta-1,4-diene-3,17-dione and 6beta-Hydroxymethylandrosta-1,4-diene-3,17-dione

  • Catalogue No.:PA 05 0541018

  • CAS :

    NA

  • Molecular Formula : C20H26O3

  • Molecular Weight : 314.43

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