flucloxacillin sodium hydrate and its Impurities
A monohydrate sodium salt of Flucloxacillin, which is an antibiotic of penicillin class. It is a narrow spectrum beta-lactum antibiotic which is used to treat infections caused by gram-positive bacteria. Reference standards of Flucloxacillin Sodium Hydrate API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
Flucloxacillin Sodium Monohydrate - Impurity E
(2S,5R,6R)-6-[[(2S,5R,6R)-6-[[3-(2-chloro-6-Fluorophenyl)-5-methyl-1,2-oxazole-4-carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid
Catalogue No.:PA 06 22050
CAS :
2924817-37-6
Molecular Formula : C27H27ClFN5O7S2
Molecular Weight : 652.11
Flucloxacillin Sodium Monohydrate - Impurity G
(2Ξ,4S)-3-Acetyl-2-[(Ξ)-carboxy[[3-(2-chloro-6-fluorophenyl)-5-methyl-1,2-oxazole-4-carbonyl]amino]methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic Acid
Catalogue No.:PA 06 0220070
CAS :
2924817-41-2
Molecular Formula : C21H21ClFN3O7S
Molecular Weight : 513.92
Flucloxacillin Sodium Monohydrate - Impurity H
(2Ξ,4S)-2-[(Ξ)-carboxy[[3-(2-chloro-6-fluorophenyl)-5-methyl-1,2-oxazole-4-carbonyl]amino]methyl]-3-[N-[3-(2-chloro-6-fluorophenyl)-5-methyl-1,2-oxazole-4-carbonyl]glycyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid
Catalogue No.:PA 33 0140080
CAS :
2924817-39-8
Molecular Formula : C32H27Cl2F2N5O9S
Molecular Weight : 766.6
Flucloxacillin Sodium Monohydrate - Impurity I
(2Ξ)-2-[[(Z)-[2-[3-(2-Chloro-6-fluorophenyl)-5-methyl-1,2-oxazol-4-yl]-5-oxo-1,3-oxazol-4(5H)- ylidene]methyl]amino]-3-methyl-3-sulfanylbutanoic Acid
Catalogue No.:PA 33 0140090
CAS :
NA
Molecular Formula : C19H17ClFN3O5S
Molecular Weight : 453.87
Flucloxacillin Sodium Monohydrate - Impurity J
(2S,5R,6R)-6-[[(2Ξ)-2-[(2Ξ,4S)-4-Carboxy-5,5-dimethyl-1,3-thiazolidin-2-yl]-2-[[3-(2-chloro-6- fluorophenyl)-5-methyl-1,2-oxazole-4-carbonyl]amino]acetyl]amino]-3,3-dimethyl-7-oxo-4-thia1-azabicyclo[3.2.0]heptane-2-carboxylic Acid,
Catalogue No.:PA 33 0140100
CAS :
NA
Molecular Formula : C27H29ClFN5O8S2
Molecular Weight : 670.12
Ethyl (2S,5R,6R)-6-amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
Ethyl (2S,5R,6R)-6-amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
Catalogue No.:PAI 06 022004
CAS :
13789-44-1
Molecular Formula : C10H16N2O3S
Molecular Weight : 244.31
Ethyl (2S,5R,6R)-6-((2S,5R,6R)-6-(3-(2-chloro-6-fluorophenyl)-5-methylisoxazole-4-carboxamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
Ethyl (2S,5R,6R)-6-((2S,5R,6R)-6-(3-(2-chloro-6-fluorophenyl)-5-methylisoxazole-4-carboxamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
Catalogue No.:PAI 06 022005
CAS :
NA
Molecular Formula : C29H31ClFN5O7S2
Molecular Weight : 680.16
