flumetasone and its Impurities
Flumetasone, also known as flumethasone. It is used to treat inflammation of the outer ear, especially if it is thought an infection is causing the swelling. Reference standards of Flumetasone API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.


(6S,9R,10S,11S,13S,16R,17R)-6,9-Difluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthrene-17-carboxylic acid
(6S,9R,10S,11S,13S,16R,17R)-6,9-Difluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthrene-17-carboxylic acid
Catalogue No.:PAI 06 001030
CAS :
28416-82-2
Molecular Formula : C21H26F2O5
Molecular Weight : 396.42


(6S,9R,10S,11S,13S,16R,17R)-17-Acetoxy-6,9-difluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthrene-17-carboxylic Acid
(6S,9R,10S,11S,13S,16R,17R)-17-Acetoxy-6,9-difluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthrene-17-carboxylic Acid
Catalogue No.:PAI 06 001031
CAS :
NA
Molecular Formula : C23H28F2O6
Molecular Weight : 438.46


(6S,9R,10S,11S,13S,16R,17R)-17-Acetoxy-6,9-difluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthrene-17-carbothioic S-acid
(6S,9R,10S,11S,13S,16R,17R)-17-Acetoxy-6,9-difluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthrene-17-carbothioic S-acid
Catalogue No.:PAI 06 001032
CAS :
NA
Molecular Formula : C23H28F2O5S
Molecular Weight : 454.53


(6S,9R,10S,11S,13S,16R,17R)-6,9-Difluoro-11-hydroxy-17-(((hydroxymethyl)thio)carbonyl)-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl Acetate
(6S,9R,10S,11S,13S,16R,17R)-6,9-Difluoro-11-hydroxy-17-(((hydroxymethyl)thio)carbonyl)-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl Acetate
Catalogue No.:PAI 06 001033
CAS :
NA
Molecular Formula : C24H30F2O6S
Molecular Weight : 484.55


2-(((6S,9R,10S,11S,13S,16R,17R)-17-Acetoxy-6,9-difluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthrene-17-carbonyl)thio)acetic acid
2-(((6S,9R,10S,11S,13S,16R,17R)-17-Acetoxy-6,9-difluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthrene-17-carbonyl)thio)acetic acid
Catalogue No.:PAI 06 001040
CAS :
NA
Molecular Formula : C25H30F2O7S
Molecular Weight : 512.56