fluocinolone acetonide and its Impurities
Fluocinolone Acetonide has been used extensively in dermatological preparations and it has also been investigated thoroughly for its use in implantable corticosteroid devices. Reference standards of Fluocinolone Acetonide API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
(6α,11β,16α)-6,9-Difluoro-11,21-dihydroxy-21-methoxy-16,17-[(1-methylethylidene)bis(oxy)]-pregna-1,4-diene-3,20-dione
(6α,11β,16α)-6,9-Difluoro-11,21-dihydroxy-21-methoxy-16,17-[(1-methylethylidene)bis(oxy)]-pregna-1,4-diene-3,20-dione
Catalogue No.:PA 06 65540
CAS :
62013-83-6
Molecular Formula : C25H32F2O7
Molecular Weight : 482.51
2-((2aR,3S,6aS,6bR,7S,8aS,8bS,11aR,12aS,12bS)-3,6b-Difluoro-7-hydroxy-6a,8a,10,10-tetramethyl-4-oxo-2,2a,3,4,6a,6b,7,8,8a,8b,11a,12,12a,12b-tetradecahydro-1H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-8b-yl)-2-oxoethyl Acetate
2-((2aR,3S,6aS,6bR,7S,8aS,8bS,11aR,12aS,12bS)-3,6b-Difluoro-7-hydroxy-6a,8a,10,10-tetramethyl-4-oxo-2,2a,3,4,6a,6b,7,8,8a,8b,11a,12,12a,12b-tetradecahydro-1H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-8b-yl)-2-oxoethyl Acetate
Catalogue No.:PA 06 65550
CAS :
1361531-96-5
Molecular Formula : C26H34F2O7
Molecular Weight : 496.54
(2S,6aS,6bR,7S,8aS,8bS,11aR,12aS,12bS)-8b-(2,2-Dihydroxyacetyl)-2,6b-difluoro-7-hydroxy-6a,8a,10,10-tetramethyl-6a,6b,7,8,8a,8b,11a,12,12a,12b-decahydro-1H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-4(2H)-one
(2S,6aS,6bR,7S,8aS,8bS,11aR,12aS,12bS)-8b-(2,2-Dihydroxyacetyl)-2,6b-difluoro-7-hydroxy-6a,8a,10,10-tetramethyl-6a,6b,7,8,8a,8b,11a,12,12a,12b-decahydro-1H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-4(2H)-one
Catalogue No.:PA 06 65560
CAS :
62042-40-4
Molecular Formula : C24H30F2O7
Molecular Weight : 468.49
(6α,9β,11β,16α)-21-(Acetyloxy)-9,11-epoxy-6-fluoro-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione
(6α,9β,11β,16α)-21-(Acetyloxy)-9,11-epoxy-6-fluoro-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione
Catalogue No.:PA 06 65600
CAS :
6598-95-4
Molecular Formula : C26H31FO7
Molecular Weight : 474.53
(6β,11β,16α)-21-(Acetyloxy)-6,9-difluoro-11-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4,14-triene-3,20-dione
(6β,11β,16α)-21-(Acetyloxy)-6,9-difluoro-11-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4,14-triene-3,20-dione
Catalogue No.:PA 06 0651000
CAS :
NA
Molecular Formula : C26H30F2O7
Molecular Weight : 492.52
(2S,6aS,6bR,7S,8aS,8bS,11aR,12aS,12bS)-2,6b-Difluoro-7-hydroxy-6a,8a,10,10-tetramethyl-8b-propionyl-1,2,6a,6b,7,8,8a,8b,11a,12,12a,12b-dodecahydro-4H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-4-one
(2S,6aS,6bR,7S,8aS,8bS,11aR,12aS,12bS)-2,6b-Difluoro-7-hydroxy-6a,8a,10,10-tetramethyl-8b-propionyl-1,2,6a,6b,7,8,8a,8b,11a,12,12a,12b-dodecahydro-4H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-4-one
Catalogue No.:PA 06 0651001
CAS :
NA
Molecular Formula : C25H32F2O5
Molecular Weight : 450.52
2-((6aS,6bR,7S,8aS,8bS,11aS,12aS,12bS)-7-Acetoxy-6b-fluoro-6a,8a,10,10-tetramethyl-4-oxo-1,2,4,6a,6b,7,8,8a,11a,12,12a,12b-dodecahydro-8bH-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-8b-yl)-2-oxoethyl acetate
2-((6aS,6bR,7S,8aS,8bS,11aS,12aS,12bS)-7-Acetoxy-6b-fluoro-6a,8a,10,10-tetramethyl-4-oxo-1,2,4,6a,6b,7,8,8a,11a,12,12a,12b-dodecahydro-8bH-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-8b-yl)-2-oxoethyl acetate
Catalogue No.:PAI 06 065001
CAS :
2796-78-3
Molecular Formula : C28H35FO8
Molecular Weight : 518.58
2-((6aS,6bR,7S,8aS,8bS,11aS,12aS,12bS)-7-Acetoxy-3,6b-difluoro-6a,8a,10,10-tetramethyl-4-oxo-1,2,4,6a,6b,7,8,8a,11a,12,12a,12b-dodecahydro-8bH-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-8b-yl)-2-oxoethyl acetate
2-((6aS,6bR,7S,8aS,8bS,11aS,12aS,12bS)-7-Acetoxy-3,6b-difluoro-6a,8a,10,10-tetramethyl-4-oxo-1,2,4,6a,6b,7,8,8a,11a,12,12a,12b-dodecahydro-8bH-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-8b-yl)-2-oxoethyl acetate
Catalogue No.:PAI 06 065002
CAS :
NA
Molecular Formula : C28H34F2O8
Molecular Weight : 536.57
