fluorometholone and its Impurities
A synthetic glucocorticoid , which is a potent anti-inflammatory agent for eyes. It helps in treatment of swelling, warmth, redness, pain in eyes and eyelids. Reference standards of Fluorometholone API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
(6S,8S,9R,10S,11S,13S,14S,17R)-17-Acetyl-9-fluoro-11,17-dihydroxy-6,10,13-trimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one
(6S,8S,9R,10S,11S,13S,14S,17R)-17-Acetyl-9-fluoro-11,17-dihydroxy-6,10,13-trimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one
Catalogue No.:PA 06 57540
CAS :
378-36-9
Molecular Formula : C22H31FO4
Molecular Weight : 378.48
(6S,10R,13S,17R)-17-Acetyl-17-hydroxy-6,10,13-trimethyl-6,7,8,10,12,13,14,15,16,17-decahydro-3H-cyclopenta[a]phenanthren-3-one
(6S,10R,13S,17R)-17-Acetyl-17-hydroxy-6,10,13-trimethyl-6,7,8,10,12,13,14,15,16,17-decahydro-3H-cyclopenta[a]phenanthren-3-one
Catalogue No.:PA 06 57550
CAS :
NA
Molecular Formula : C22H28O3
Molecular Weight : 340.46
(6S,9R,10S,11S,13S,17R)-17-Acetyl-9-bromo-11,17-dihydroxy-6,10,13-trimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one
(6S,9R,10S,11S,13S,17R)-17-Acetyl-9-bromo-11,17-dihydroxy-6,10,13-trimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one
Catalogue No.:PA 06 57560
CAS :
NA
Molecular Formula : C22H29BrO4
Molecular Weight : 437.37
(6S,8S,10R,13S,14S,17R)-17-Acetyl-17-hydroxy-6,10,13-trimethyl-6,7,8,10,12,13,14,15,16,17-decahydro-3H-cyclopenta[a]phenanthren-3-one
(6S,8S,10R,13S,14S,17R)-17-Acetyl-17-hydroxy-6,10,13-trimethyl-6,7,8,10,12,13,14,15,16,17-decahydro-3H-cyclopenta[a]phenanthren-3-one
Catalogue No.:PA 06 57580
CAS :
110664-42-1
Molecular Formula : C22H28O3
Molecular Weight : 340.46
(6S,8S,9R,10S,11S,13S,14S,17R)-17-Acetyl-9-bromo-11,17-dihydroxy-6,10,13-trimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[α]phenanthren-3-one
(6S,8S,9R,10S,11S,13S,14S,17R)-17-Acetyl-9-bromo-11,17-dihydroxy-6,10,13-trimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[α]phenanthren-3-one
Catalogue No.:PA 06 57590
CAS :
110664-58-9
Molecular Formula : C22H29BrO4
Molecular Weight : 437.37
(6S,8S,9R,10S,11S,13S,14S,17R)-17-Acetyl-9-chloro-11,17-dihydroxy-6,10,13-trimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one
(6S,8S,9R,10S,11S,13S,14S,17R)-17-Acetyl-9-chloro-11,17-dihydroxy-6,10,13-trimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one
Catalogue No.:PA 06 57610
CAS :
NA
Molecular Formula : C22H29ClO4
Molecular Weight : 392.92
(6S,9R,10S,11S,13S,14S)-17-Acetyl-9-fluoro-11-hydroxy-6,10,13-trimethyl-6,7,8,9,10,11,12,13,14,15-decahydro-3H-cyclopenta[a]phenanthren-3-one
(6S,9R,10S,11S,13S,14S)-17-Acetyl-9-fluoro-11-hydroxy-6,10,13-trimethyl-6,7,8,9,10,11,12,13,14,15-decahydro-3H-cyclopenta[a]phenanthren-3-one
Catalogue No.:PA 06 57620
CAS :
2061-13-4
Molecular Formula : C22H27FO3
Molecular Weight : 358.45
Fluorometholone Related Compound A (11Beta,17alpha-Dihydroxy-6alpha-methylpregna-1,4-diene-3,20-dio (1278018)
Fluorometholone Related Compound A (11Beta,17alpha-Dihydroxy-6alpha-methylpregna-1,4-diene-3,20-dio (1278018)
Catalogue No.:PA USP1278018
CAS :
6870-94-6
Molecular Formula : NA
Molecular Weight : NA
2-((6S,8S,9R,10S,11S,13S,14S,17R)-9-Fluoro-11,17-dihydroxy-6,10,13-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl Methanesulfonate
2-((6S,8S,9R,10S,11S,13S,14S,17R)-9-Fluoro-11,17-dihydroxy-6,10,13-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl Methanesulfonate
Catalogue No.:PA 06 57640
CAS :
2796-99-8
Molecular Formula : C23H31FO7S
Molecular Weight : 470.55
(1R,4aS,4bS,6S,10aS,10bR,11S,12aS)-10b-Fluoro-1,11-dihydroxy-1,6,10a,12a-tetramethyl-1,3,4,4a,4b,5,6,10a,10b,11,12,12a-dodecahydrochrysene-2,8-dione
(1R,4aS,4bS,6S,10aS,10bR,11S,12aS)-10b-Fluoro-1,11-dihydroxy-1,6,10a,12a-tetramethyl-1,3,4,4a,4b,5,6,10a,10b,11,12,12a-dodecahydrochrysene-2,8-dione
Catalogue No.:PA 06 57650
CAS :
2412488-81-2
Molecular Formula : C22H29FO4
Molecular Weight : 376.47
(6S,8S,9S,10S,11R,13S,14S,17R)-17-Acetyl-9-bromo-17-hydroxy-6,10,13-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthrene-11-carboxylic Acid
(6S,8S,9S,10S,11R,13S,14S,17R)-17-Acetyl-9-bromo-17-hydroxy-6,10,13-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthrene-11-carboxylic Acid
Catalogue No.:PA 06 57660
CAS :
NA
Molecular Formula : C23H29BrO5
Molecular Weight : 465.38
2-((6S,8S,9S,10R,11S,13S,14S,17R)-11,17-Dihydroxy-6,10,13-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl Methanesulfonate
2-((6S,8S,9S,10R,11S,13S,14S,17R)-11,17-Dihydroxy-6,10,13-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl Methanesulfonate
Catalogue No.:PAI 06 057001
CAS :
51474-81-8
Molecular Formula : C23H32O7S
Molecular Weight : 452.56
(6S,8S,9S,10R,11S,13S,14S,17R)-17-(2-Chloroacetyl)-11,17-dihydroxy-6,10,13-trimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one
(6S,8S,9S,10R,11S,13S,14S,17R)-17-(2-Chloroacetyl)-11,17-dihydroxy-6,10,13-trimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one
Catalogue No.:PAI 06 057002
CAS :
97296-59-8
Molecular Formula : C22H29ClO4
Molecular Weight : 392.92
(6S,8S,9S,10R,11S,13S,14S,17R)-11,17-Dihydroxy-6,10,13-trimethyl-17-propionyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one
(6S,8S,9S,10R,11S,13S,14S,17R)-11,17-Dihydroxy-6,10,13-trimethyl-17-propionyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one
Catalogue No.:PAI 06 057003
CAS :
NA
Molecular Formula : C23H32O4
Molecular Weight : 372.51
(6S,8S,10R,13S,14S,17R)-17-Hydroxy-6,10,13-trimethyl-17-propionyl-6,7,8,10,12,13,14,15,16,17-decahydro-3H-cyclopenta[a]phenanthren-3-one
(6S,8S,10R,13S,14S,17R)-17-Hydroxy-6,10,13-trimethyl-17-propionyl-6,7,8,10,12,13,14,15,16,17-decahydro-3H-cyclopenta[a]phenanthren-3-one
Catalogue No.:PAI 06 057004
CAS :
NA
Molecular Formula : C23H30O3
Molecular Weight : 354.49
(6S,8S,9R,10S,13S,14S,17R)-17-acetyl-9-chloro-11,17-dihydroxy-6,10,13-trimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one
(6S,8S,9R,10S,13S,14S,17R)-17-acetyl-9-chloro-11,17-dihydroxy-6,10,13-trimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one
Catalogue No.:PA 06 0571000
CAS :
2122283-37-6
Molecular Formula : C22H29ClO4
Molecular Weight : 392.92
(8S,9R,10S,11S,13S,14S)-9-Fluoro-11-hydroxy-10,13-dimethyl-7,8,9,10,11,12,13,14,15,16-decahydro-3H-cyclopenta[a]phenanthrene-3,17(6H)-dione
(8S,9R,10S,11S,13S,14S)-9-Fluoro-11-hydroxy-10,13-dimethyl-7,8,9,10,11,12,13,14,15,16-decahydro-3H-cyclopenta[a]phenanthrene-3,17(6H)-dione
Catalogue No.:PA 06 0571001
CAS :
3868-89-1
Molecular Formula : C19H23FO3
Molecular Weight : 318.39
(3bR,3cR,4S,5aS,6R,8aS,8bS,10S)-6-Acetyl-3c-fluoro-4,6-dihydroxy-3b,5a,10-trimethyl-2a,3a,3b,3c,4,5,5a,6,7,8,8a,8b,9,10-tetradecahydro-2H-cyclopenta[7,8]phenanthro[3,4-b]oxiren-2-one
(3bR,3cR,4S,5aS,6R,8aS,8bS,10S)-6-Acetyl-3c-fluoro-4,6-dihydroxy-3b,5a,10-trimethyl-2a,3a,3b,3c,4,5,5a,6,7,8,8a,8b,9,10-tetradecahydro-2H-cyclopenta[7,8]phenanthro[3,4-b]oxiren-2-one
Catalogue No.:PA 06 0571005
CAS :
NA
Molecular Formula : C22H29FO5
Molecular Weight : 392.47
(6S,8S,9R,10S,13S,14S)-17-Acetyl-9-fluoro-6,10,13-trimethyl-6,7,8,9,10,13,14,15-octahydro-3H-cyclopenta[a]phenanthren-3-one
(6S,8S,9R,10S,13S,14S)-17-Acetyl-9-fluoro-6,10,13-trimethyl-6,7,8,9,10,13,14,15-octahydro-3H-cyclopenta[a]phenanthren-3-one
Catalogue No.:PA 06 0571004
CAS :
NA
Molecular Formula : C22H25FO2
Molecular Weight : 340.44
(6S,8S,9R,10S,11R,13S,14S,17S)-17-Acetyl-9-fluoro-17-hydroxy-11-methoxy-6,10,13-trimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one
(6S,8S,9R,10S,11R,13S,14S,17S)-17-Acetyl-9-fluoro-17-hydroxy-11-methoxy-6,10,13-trimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one
Catalogue No.:PA 06 0571003
CAS :
NA
Molecular Formula : C23H31FO4
Molecular Weight : 390.5
(6S,10S,11S,13S,14S,17R)-17-Acetyl-11,17-dihydroxy-6,10,13-trimethyl-6,7,10,11,12,13,14,15,16,17-decahydro-3H-cyclopenta[a]phenanthren-3-one
(6S,10S,11S,13S,14S,17R)-17-Acetyl-11,17-dihydroxy-6,10,13-trimethyl-6,7,10,11,12,13,14,15,16,17-decahydro-3H-cyclopenta[a]phenanthren-3-one
Catalogue No.:PA 06 0571002
CAS :
NA
Molecular Formula : C22H28O4
Molecular Weight : 356.46
(3bR,3cR,4S,5aS,6R,8aS,8bS,10S)-6-Acetyl-3c-fluoro-4,6-dihydroxy-3b,5a,10-trimethyl-2a,3a,3b,3c,4,5,5a,6,7,8,8a,8b,9,10-tetradecahydro-2H-cyclopenta[7,8]phenanthro[3,4-b]oxiren-2-one
(3bR,3cR,4S,5aS,6R,8aS,8bS,10S)-6-Acetyl-3c-fluoro-4,6-dihydroxy-3b,5a,10-trimethyl-2a,3a,3b,3c,4,5,5a,6,7,8,8a,8b,9,10-tetradecahydro-2H-cyclopenta[7,8]phenanthro[3,4-b]oxiren-2-one
Catalogue No.:PA 06 0571006
CAS :
NA
Molecular Formula : C22H29FO5
Molecular Weight : 392.47
(6S,8S,9R,10R,11R,13S,14S,17R)-17-Acetyl-9-fluoro-1,11,17-trihydroxy-6,10,13-trimethylhexadecahydro-3H-cyclopenta[a]phenanthren-3-one
(6S,8S,9R,10R,11R,13S,14S,17R)-17-Acetyl-9-fluoro-1,11,17-trihydroxy-6,10,13-trimethylhexadecahydro-3H-cyclopenta[a]phenanthren-3-one
Catalogue No.:PA 06 0571007
CAS :
NA
Molecular Formula : C22H33FO5
Molecular Weight : 396.5
