Fosaprepitant Dimeglumine is aids in the prevention of acute and delayed nausea and vomiting associated with chemotherapy treatment. It is an intravenously administered antiemetic drug. It is a prodrug of Aprepitant. Reference standards of Fosaprepitant Dimeglumine API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
Fosaprepitant Dimeglumine
Catalogue No.:PA 06 94000
CAS :
Molecular Formula : C37H56F7N6O16P
Molecular Weight : 1004.83
Aprepitant
Catalogue No.:PA 06 94510
Molecular Formula : C23H21F7N4O3
Molecular Weight : 534.43
N-(Destriazolonomethyl) N-(Methylcarboxyacetamidohydrazono) Aprepitant
Catalogue No.:PA 06 94520
Molecular Formula : C24H25F7N4O4
Molecular Weight : 566.47
Fosaprepitant Dimeglumine Dibenzylester Impurity
Catalogue No.:PA 06 94530
Molecular Formula : C37H34F7N4O6P
Molecular Weight : 794.65
Fosaprepitant (R,R,R)-Isomer
Catalogue No.:PA 06 94540
Fosaprepitant Desfluoro Impurity
Catalogue No.:PA 06 94550
Molecular Formula : C23H23F6N4O6P
Molecular Weight : 596.42
Fosaprepitant Enantiomer
Catalogue No.:PA 06 94560
Molecular Formula : C23H22F7N4O6P
Molecular Weight : 614.41
3-(((2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-1H-1,2,4-triazol-5(4H)-one
Catalogue No.:PA 06 94570
(2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentaol hemi((3-(((2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonate)
Catalogue No.:PA 06 94580
Fosaprepitant Dimeglumine Desfluoro Impurity
Catalogue No.:PA 06 94590
Molecular Formula : C37H57F6N6O16P
Molecular Weight : 986.84
(2R,3R,4R,5S)-6-(Methylamino)hexane-1,2,3,4,5-pentaol hemi((3-(((2R,3R)-2-((S)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonate)
Catalogue No.:PA 06 94600
Methyl (E)-2-(1-amino-2-((2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)ethylidene)hydrazine-1-carboxylate
Catalogue No.:PA 06 94610
Molecular Weight : 566.48
(1’S,2R,3S)-Fosaprepitant Dimeglumine
Catalogue No.:PA 06 94620
Molecular Weight : 1004.84
(4-Benzyl-3-(((2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(p-tolyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic Acid
Catalogue No.:PA 06 94630
Molecular Formula : C31H31F6N4O6P
Molecular Weight : 700.58
Fosaprepitant N-oxide
Catalogue No.:PA 06 94640
Molecular Formula : C23H22F7N4O7P
Molecular Weight : 630.41
Methyl (Z)-2-(1-amino-2-((2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)ethylidene)hydrazine-1-carboxylate
Catalogue No.:PA 06 94650
(2R,3R,4R,5S)-6-(Methylamino)hexane-1,2,3,4,5-pentaol hemi((3-(((2S,3R)-2-((S)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonate)
Catalogue No.:PA 06 0941000
(3-(((2S,3R)-2-((R)-1-(3,5-bis(Trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic Acid
Catalogue No.:PA 06 0941001
(3-(((2R,3S)-2-((S)-1-(3,5-bis(Trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic Acid
Catalogue No.:PA 06 0941002
(1’S,2R,3R)-Fosaprepitant Dimeglumine
Catalogue No.:PA 06 0941003
(3-(((2R,3R)-2-((R)-1-(3,5-bis(Trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic Acid
Catalogue No.:PA 06 0941004
(3-(((2S,3S)-2-((S)-1-(3,5-bis(Trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic Acid
Catalogue No.:PA 06 0941005
(2R,3R,4R,5S)-6-(Methylamino)hexane-1,2,3,4,5-pentaol hemi((3-(((2S,3S)-2-((S)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonate)
Catalogue No.:PA 06 0941006
(3-(((2R,3R)-2-((S)-1-(3,5-bis(Trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic Acid
Catalogue No.:PA 06 0941007
(3-(((2S,3S)-2-((R)-1-(3,5-bis(Trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic Acid
Catalogue No.:PA 06 0941008
(4-Benzyl-3-(((2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic acid
Catalogue No.:PA 06 0941009
Molecular Formula : C30H28F7N4O6P
Molecular Weight : 704.54
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