fosaprepitant and its Impurities
Fosaprepitant is aids in the prevention of acute and delayed nausea and vomiting associated with chemotherapy treatment. It is an intravenously administered antiemetic drug. It is a prodrug of Aprepitant. Reference standards of Fosaprepitant API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
(2R,3S)-4-Benzyl-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholine
(2R,3S)-4-Benzyl-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholine
Catalogue No.:PA 33 0121000
CAS :
2377328-01-1
Molecular Formula : C27H24F7NO2
Molecular Weight : 527.48
Dibenzyl (3-(((2S,3R)-2-((S)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-1H-1,2,4-triazole-1,4(5H)-diyl)bis(hydrogen phosphonate)
Dibenzyl (3-(((2S,3R)-2-((S)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-1H-1,2,4-triazole-1,4(5H)-diyl)bis(hydrogen phosphonate)
Catalogue No.:PA 33 0121002
CAS :
NA
Molecular Formula : C37H35F7N4O9P2
Molecular Weight : 874.64
(2R)-4-Benzyl-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholin-3-ol
(2R)-4-Benzyl-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholin-3-ol
Catalogue No.:PA 33 0121003
CAS :
1651828-04-4
Molecular Formula : C27H24F7NO3
Molecular Weight : 543.48
5-(((2R,3S)-3-((S)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-2-(4-fluorophenyl)morpholino)methyl)-1,2-dihydro-3H-1,2,4-triazol-3-one
5-(((2R,3S)-3-((S)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-2-(4-fluorophenyl)morpholino)methyl)-1,2-dihydro-3H-1,2,4-triazol-3-one
Catalogue No.:PA 33 0121006
CAS :
NA
Molecular Formula : C23H21F7N4O3
Molecular Weight : 534.43
