Foscarbidopa and its Impurities

Foscarbidopa is part of a fixed-dose combination drug with foslevodopa, marketed under the brand name Vyalev. This combination is used to treat advanced Parkinson’s disease, particularly in patients experiencing motor fluctuations due to inconsistent dopamine levels. Reference standards of Foscarbidopa API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.