Fostamatinib and its Impurities
Fostamatinib, sold under the brand names Tavalisse and Tavlesse, is a tyrosine kinase inhibitor medication for the treatment of chronic immune thrombocytopenia. Reference standards of Fostamatinib API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.


6-((5-fluoro-2-((3,4,5-trimethoxyphenyl)amino)pyrimidin-4-yl)amino)-2,2-dimethyl-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one
6-((5-fluoro-2-((3,4,5-trimethoxyphenyl)amino)pyrimidin-4-yl)amino)-2,2-dimethyl-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one
Catalogue No.:PA 06 2031000
CAS :
841290-80-0
Molecular Formula : C22H23FN6O5
Molecular Weight : 470.46