ganaxolone and its Impurities
Ganaxolone is an allosteric modulator of GABAA receptors acting through binding sites which are distinct from the benzodiazepine binding site. It has activity in a broad range of animal models of epilepsy. Ganaxolone is an experimental drug. Reference standards of Ganaxolone API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.


1-((3S,5S,8R,9S,10S,13S,14S,17S)-3-Hydroxy-3,10,13-trimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)ethan-1-one
1-((3S,5S,8R,9S,10S,13S,14S,17S)-3-Hydroxy-3,10,13-trimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)ethan-1-one
Catalogue No.:PA 07 0801000
CAS :
1264737-31-6
Molecular Formula : C22H36O2
Molecular Weight : 332.53


1-((5S,8R,9S,10S,13S,14S,17S)-3,10,13-Trimethyl-4,5,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)ethan-1-one
1-((5S,8R,9S,10S,13S,14S,17S)-3,10,13-Trimethyl-4,5,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)ethan-1-one
Catalogue No.:PA 07 0801002
CAS :
NA
Molecular Formula : C22H34O
Molecular Weight : 314.51


1-((3R,5S,8R,9S,10S,13S,14S,17S)-10,13-Dimethylhexadecahydrospiro[cyclopenta[a]phenanthrene-3,2'-oxiran]-17-yl)ethan-1-one
1-((3R,5S,8R,9S,10S,13S,14S,17S)-10,13-Dimethylhexadecahydrospiro[cyclopenta[a]phenanthrene-3,2'-oxiran]-17-yl)ethan-1-one
Catalogue No.:PA 07 0801001
CAS :
148256-45-5
Molecular Formula : C22H34O2
Molecular Weight : 330.51


1-((8R,9S,10S,13S,14S,17S)-10,13-Dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)ethan-1-one
1-((8R,9S,10S,13S,14S,17S)-10,13-Dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)ethan-1-one
Catalogue No.:PA 07 0801003
CAS :
32695-80-0
Molecular Formula : C21H34O
Molecular Weight : 302.5