gefitinib and its Impurities

Gefitinib is used to treat lung cancer. Acting in a similar manner to erlotinib gefitinib selectively targets the mutant proteins in malignant cells. It is marketed by AstraZeneca under the trade name Iressa. Reference standards of Gefitinib API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

Displaying 46 results for gefitinib Impurities
PA 07 24000

Gefitinib

Gefitinib

  • Catalogue No.:PA 07 24000

  • CAS :

    184475-35-2

  • Molecular Formula : C22H24ClFN4O3

  • Molecular Weight : 446.90

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PA 07 24010

Gefitinib - Impurity A

7-Methoxy-6-[3-(morpholin-4-yl)propoxy]quinazolin-4(1H)-one

  • Catalogue No.:PA 07 24010

  • CAS :

    199327-61-2

  • Molecular Formula : C16H21N3O4

  • Molecular Weight : 319.36

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PA 07 24020

Gefitinib - Impurity B

3-Deschloro-4-desfluoro-4-chloro-3-fluoro Gefitinib

  • Catalogue No.:PA 07 24020

  • CAS :

    1603814-04-5

  • Molecular Formula : C22H24ClFN4O3

  • Molecular Weight : 446.90

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PA 07 24510

3-Chloro-4-fluorophenylamine

3-Chloro-4-fluorophenylamine

  • Catalogue No.:PA 07 24510

  • CAS :

    367-21-5

  • Molecular Formula : C6H5ClFN

  • Molecular Weight : 145.56

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PA 07 24520

Gefitinib 4-Desfluoro Hydrochloride Impurity

Gefitinib 4-Desfluoro Hydrochloride Impurity

  • Catalogue No.:PA 07 24520

  • CAS :

    NA

  • Molecular Formula : C22H26Cl2N4O3

  • Molecular Weight : 465.37

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PA 07 24530

Gefitinib N-Oxide

Gefitinib N-Oxide

  • Catalogue No.:PA 07 24530

  • CAS :

    847949-51-3

  • Molecular Formula : C22H24ClFN4O4

  • Molecular Weight : 462.9

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PA 07 24540

O-Desmorpholinopropyl Gefitinib

O-Desmorpholinopropyl Gefitinib

  • Catalogue No.:PA 07 24540

  • CAS :

    184475-71-6

  • Molecular Formula : C15H11ClFN3O2

  • Molecular Weight : 319.72

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PA 07 24550

N-(3-Chloro-4-fluorophenyl)-N-(7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-yl)hydroxylamine

N-(3-Chloro-4-fluorophenyl)-N-(7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-yl)hydroxylamine

  • Catalogue No.:PA 07 24550

  • CAS :

    NA

  • Molecular Formula : C22H24ClFN4O4

  • Molecular Weight : 462.9

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PA 07 24560

4-(3-((4-((3-Chloro-4-fluorophenyl)(hydroxy)amino)-7-methoxyquinazolin-6-yl)oxy)propyl)morpholine 4-oxide

4-(3-((4-((3-Chloro-4-fluorophenyl)(hydroxy)amino)-7-methoxyquinazolin-6-yl)oxy)propyl)morpholine 4-oxide

  • Catalogue No.:PA 07 24560

  • CAS :

    NA

  • Molecular Formula : C22H24ClFN4O5

  • Molecular Weight : 478.9

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PA 07 24570

3,4-Dichloroaniline

3,4-Dichloroaniline

  • Catalogue No.:PA 07 24570

  • CAS :

    95-76-1

  • Molecular Formula : C6H5Cl2N

  • Molecular Weight : 162.02

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PA 07 24580

N-(3-Morpholinopropyl) Gefitinib

N-(3-Morpholinopropyl) Gefitinib

  • Catalogue No.:PA 07 24580

  • CAS :

    1502829-45-9

  • Molecular Formula : C29H37ClFN5O4

  • Molecular Weight : 574.09

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PA 07 24590

N-(3-Chloro-4-fluorophenyl)-6,7-dimethoxyquinazolin-4-amine

N-(3-Chloro-4-fluorophenyl)-6,7-dimethoxyquinazolin-4-amine

  • Catalogue No.:PA 07 24590

  • CAS :

    153437-78-6

  • Molecular Formula : C16H13ClFN3O2

  • Molecular Weight : 333.74

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PA 07 24600

N-(4-Fluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine

N-(4-Fluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine

  • Catalogue No.:PA 07 24600

  • CAS :

    2254241-82-0

  • Molecular Formula : C22H25FN4O3

  • Molecular Weight : 412.46

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PA 07 24610

4-(3-((4-Chloro-7-methoxyquinazolin-6-yl)oxy)propyl)morpholine

4-(3-((4-Chloro-7-methoxyquinazolin-6-yl)oxy)propyl)morpholine

  • Catalogue No.:PA 07 24610

  • CAS :

    199327-59-8

  • Molecular Formula : C16H20ClN3O3

  • Molecular Weight : 337.8

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PA 07 24620

O-Desmethyl Gefitinib

O-Desmethyl Gefitinib

  • Catalogue No.:PA 07 24620

  • CAS :

    847949-49-9

  • Molecular Formula : C21H22ClFN4O3

  • Molecular Weight : 432.88

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PA 07 24630

N-(3,4-Difluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine

N-(3,4-Difluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine

  • Catalogue No.:PA 07 24630

  • CAS :

    184475-50-1

  • Molecular Formula : C22H24F2N4O3

  • Molecular Weight : 430.45

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PA 07 24640

4-Defluoro-4-hydroxy Gefitinib

4-Defluoro-4-hydroxy Gefitinib

  • Catalogue No.:PA 07 24640

  • CAS :

    847949-50-2

  • Molecular Formula : C22H25ClN4O4

  • Molecular Weight : 444.91

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PA 07 24650

N-(3,4-Dichlorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine

N-(3,4-Dichlorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine

  • Catalogue No.:PA 07 24650

  • CAS :

    2089650-13-3

  • Molecular Formula : C22H24Cl2N4O3

  • Molecular Weight : 463.36

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PA 07 24660

3-(3-Chloro-4-fluorophenyl)-7-methoxy-4-oxo-3,4-dihydroquinazolin-6-yl Acetate

3-(3-Chloro-4-fluorophenyl)-7-methoxy-4-oxo-3,4-dihydroquinazolin-6-yl Acetate

  • Catalogue No.:PA 07 24660

  • CAS :

    2512211-98-0

  • Molecular Formula : C17H12ClFN2O4

  • Molecular Weight : 362.74

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PA 07 24670

3-(3-Chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4(3H)-one

3-(3-Chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4(3H)-one

  • Catalogue No.:PA 07 24670

  • CAS :

    1608115-59-8

  • Molecular Formula : C22H23ClFN3O4

  • Molecular Weight : 447.89

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PA 07 24680

7,8-Dichloro-N-(3-chloro-4-fluorophenyl)-6-(3-morpholinopropoxy)quinazolin-4-amine

7,8-Dichloro-N-(3-chloro-4-fluorophenyl)-6-(3-morpholinopropoxy)quinazolin-4-amine

  • Catalogue No.:PA 07 24680

  • CAS :

    2921918-23-0

  • Molecular Formula : C21H20Cl3FN4O2

  • Molecular Weight : 485.77

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PA 07 24690

6-Hydroxy-7-methoxy-4(1H)-quinazolinone

6-Hydroxy-7-methoxy-4(1H)-quinazolinone

  • Catalogue No.:PA 07 24690

  • CAS :

    179688-52-9

  • Molecular Formula : C9H8N2O3

  • Molecular Weight : 192.17

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PA 07 24700

4-Isopropoxy-7-methoxyquinazolin-6-yl acetate

4-Isopropoxy-7-methoxyquinazolin-6-yl acetate

  • Catalogue No.:PA 07 24700

  • CAS :

    NA

  • Molecular Formula : C14H16N2O4

  • Molecular Weight : 276.29

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PA STI 044040

Gefitinib-d3

Gefitinib-d3

  • Catalogue No.:PA STI 044040

  • CAS :

    1173976-40-3

  • Molecular Formula : C22H21D3ClFN4O3

  • Molecular Weight : 449.92

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PA IPIPRS 240 12

Gefitinib (IPRS/240/12)-from IPC

  • Catalogue No.:PA IPIPRS 240 12

  • CAS :

    NA

  • Molecular Formula :

  • Molecular Weight : NA

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PA EPY0001809

Gefitinib for system suitability (Y0001809)

Gefitinib for system suitability (Y0001809)

  • Catalogue No.:PA EPY0001809

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

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PA EPY0001813

Gefitinib (Y0001813)

Gefitinib (Y0001813)

  • Catalogue No.:PA EPY0001813

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

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PA 07 24730

1-(2-amino-4’-methoxy-[1,1’-biphenyl]-4-yl)ethanone

1-(2-amino-4’-methoxy-[1,1’-biphenyl]-4-yl)ethanone

  • Catalogue No.:PA 07 24730

  • CAS :

    246512-44-7

  • Molecular Formula : C15H23N3O4

  • Molecular Weight : 309.36

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PA 07 24740

2-Amino-4-methoxy-5-[3-(4-morpholinyl)propoxy]benzamide

2-Amino-4-methoxy-5-[3-(4-morpholinyl)propoxy]benzamide

  • Catalogue No.:PA 07 24740

  • CAS :

    1640351-46-7

  • Molecular Formula : C15H22N2O5

  • Molecular Weight : 310.35

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PA 07 24710

2-Amino-4-methoxy-5-(3-morpholinopropoxy)benzonitrile

2-Amino-4-methoxy-5-(3-morpholinopropoxy)benzonitrile

  • Catalogue No.:PA 07 24710

  • CAS :

    675126-27-9

  • Molecular Formula : C15H21N3O3

  • Molecular Weight : 291.35

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PA 07 24720

4-Methoxy-5-(3-morpholinopropoxy)-2-nitrobenzonitrile

4-Methoxy-5-(3-morpholinopropoxy)-2-nitrobenzonitrile

  • Catalogue No.:PA 07 24720

  • CAS :

    675126-26-8

  • Molecular Formula : C15H19N3O5

  • Molecular Weight : 321.33

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PA 07 24750

N'-(2-Cyano-5-methoxy-4-(3-morpholinopropoxy)phenyl)-N,N-dimethylformimidamide

N'-(2-Cyano-5-methoxy-4-(3-morpholinopropoxy)phenyl)-N,N-dimethylformimidamide

  • Catalogue No.:PA 07 24750

  • CAS :

    950596-57-3

  • Molecular Formula : C18H26N4O3

  • Molecular Weight : 346.43

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PA 07 24760

8-Methoxy-4-oxo-3,4-dihydroquinazolin-7-yl acetate

8-Methoxy-4-oxo-3,4-dihydroquinazolin-7-yl acetate

  • Catalogue No.:PA 07 24760

  • CAS :

    2469273-16-1

  • Molecular Formula : C11H10N2O4

  • Molecular Weight : 234.21

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PA 07 24770

7-Methoxy-4-oxo-3,4-dihydroquinazolin-8-yl Acetate

7-Methoxy-4-oxo-3,4-dihydroquinazolin-8-yl Acetate

  • Catalogue No.:PA 07 24770

  • CAS :

    NA

  • Molecular Formula : C11H10N2O4

  • Molecular Weight : 234.21

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PA STI 044041

Gefitinib-d8

Gefitinib-d8

  • Catalogue No.:PA STI 044041

  • CAS :

    857091-32-8

  • Molecular Formula : C22H16D8ClFN4O3

  • Molecular Weight : 454.96

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PA 07 0241000

4-chloro-7-methoxyquinazolin-6-yl acetate

4-chloro-7-methoxyquinazolin-6-yl acetate

  • Catalogue No.:PA 07 0241000

  • CAS :

    230955-75-6

  • Molecular Formula : C11H9ClN2O3

  • Molecular Weight : 252.65

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PA 07 0241001

Methyl 2-amino-4-methoxy-5-(3-morpholinopropoxy)benzoate

Methyl 2-amino-4-methoxy-5-(3-morpholinopropoxy)benzoate

  • Catalogue No.:PA 07 0241001

  • CAS :

    214472-41-0

  • Molecular Formula : C16H24N2O5

  • Molecular Weight : 324.38

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PA 07 0241002

Methyl 4-methoxy-5-(3-morpholinopropoxy)-2-nitrobenzoate

Methyl 4-methoxy-5-(3-morpholinopropoxy)-2-nitrobenzoate

  • Catalogue No.:PA 07 0241002

  • CAS :

    214472-37-4

  • Molecular Formula : C16H22N2O7

  • Molecular Weight : 354.36

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PA 07 0241003

Gefitinib Nitroso Impurity

Gefitinib Nitroso Impurity

  • Catalogue No.:PA 07 0241003

  • CAS :

    NA

  • Molecular Formula : C22H23ClFN5O4

  • Molecular Weight : 475.91

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PA STI 089397

Gefitinib-D6

Gefitinib-D6

  • Catalogue No.:PA STI 089397

  • CAS :

    1228664-49-0

  • Molecular Formula : C22H18D6ClFN4O3

  • Molecular Weight : 452.94

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PA 07 0241004

4-(3-Bromopropyl)morpholine Hydrochloride

4-(3-Bromopropyl)morpholine Hydrochloride

  • Catalogue No.:PA 07 0241004

  • CAS :

    134187-43-2

  • Molecular Formula : C7H15BrClNO

  • Molecular Weight : 244.56

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PA 07 0241005

4-Hydroxy-7-methoxyquinazolin-6-yl Ester Acetic Acid

4-Hydroxy-7-methoxyquinazolin-6-yl Ester Acetic Acid

  • Catalogue No.:PA 07 0241005

  • CAS :

    179688-53-0

  • Molecular Formula : C11H10N2O4

  • Molecular Weight : 234.21

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PA 07 0241006

1,3-Dimorpholinopropane

1,3-Dimorpholinopropane

  • Catalogue No.:PA 07 0241006

  • CAS :

    48152-09-6

  • Molecular Formula : C11H22N2O2

  • Molecular Weight : 214.31

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PA IPRSG017

Gefitinib (IPRSG017)

Gefitinib (IPRSG017)

  • Catalogue No.:PA IPRSG017

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

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PA 07 0241007

6,7-Dimethoxyquinazolin-4(3H)-one

6,7-Dimethoxyquinazolin-4(3H)-one

  • Catalogue No.:PA 07 0241007

  • CAS :

    13794-72-4

  • Molecular Formula : C10H10N2O3

  • Molecular Weight : 206.2

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PA 07 0241008

Methyl 2-amino-4,5-dimethoxybenzoate

Methyl 2-amino-4,5-dimethoxybenzoate

  • Catalogue No.:PA 07 0241008

  • CAS :

    26759-46-6

  • Molecular Formula : C10H13NO4

  • Molecular Weight : 211.22

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CPHI INDIA- 28, 30 November