gefitinib and its Impurities

Gefitinib is used to treat lung cancer. Acting in a similar manner to erlotinib gefitinib selectively targets the mutant proteins in malignant cells. It is marketed by AstraZeneca under the trade name Iressa. Reference standards of Gefitinib API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

Displaying 49 results for gefitinib Impurities
Drug Reference Standards & Impurity Synthesis in India
PA 07 24000

Gefitinib

Gefitinib

  • Catalogue No.:PA 07 24000

  • CAS :

    184475-35-2

  • Molecular Formula : C22H24ClFN4O3

  • Molecular Weight : 446.90

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Drug Reference Standards & Impurity Synthesis in India
PA 07 24010

Gefitinib - Impurity A

7-Methoxy-6-[3-(morpholin-4-yl)propoxy]quinazolin-4(1H)-one

  • Catalogue No.:PA 07 24010

  • CAS :

    199327-61-2

  • Molecular Formula : C16H21N3O4

  • Molecular Weight : 319.36

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Drug Reference Standards & Impurity Synthesis in India
PA 07 24020

Gefitinib - Impurity B

3-Deschloro-4-desfluoro-4-chloro-3-fluoro Gefitinib

  • Catalogue No.:PA 07 24020

  • CAS :

    1603814-04-5

  • Molecular Formula : C22H24ClFN4O3

  • Molecular Weight : 446.90

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Drug Reference Standards & Impurity Synthesis in India
PA 07 24510

3-Chloro-4-fluorophenylamine

3-Chloro-4-fluorophenylamine

  • Catalogue No.:PA 07 24510

  • CAS :

    367-21-5

  • Molecular Formula : C6H5ClFN

  • Molecular Weight : 145.56

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Drug Reference Standards & Impurity Synthesis in India
PA 07 24520

Gefitinib 4-Desfluoro Hydrochloride Impurity

Gefitinib 4-Desfluoro Hydrochloride Impurity

  • Catalogue No.:PA 07 24520

  • CAS :

    NA

  • Molecular Formula : C22H26Cl2N4O3

  • Molecular Weight : 465.37

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Drug Reference Standards & Impurity Synthesis in India
PA 07 24530

Gefitinib N-Oxide

Gefitinib N-Oxide

  • Catalogue No.:PA 07 24530

  • CAS :

    847949-51-3

  • Molecular Formula : C22H24ClFN4O4

  • Molecular Weight : 462.9

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Drug Reference Standards & Impurity Synthesis in India
PA 07 24540

O-Desmorpholinopropyl Gefitinib

O-Desmorpholinopropyl Gefitinib

  • Catalogue No.:PA 07 24540

  • CAS :

    184475-71-6

  • Molecular Formula : C15H11ClFN3O2

  • Molecular Weight : 319.72

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Drug Reference Standards & Impurity Synthesis in India
PA 07 24550

N-(3-Chloro-4-fluorophenyl)-N-(7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-yl)hydroxylamine

N-(3-Chloro-4-fluorophenyl)-N-(7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-yl)hydroxylamine

  • Catalogue No.:PA 07 24550

  • CAS :

    NA

  • Molecular Formula : C22H24ClFN4O4

  • Molecular Weight : 462.9

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Drug Reference Standards & Impurity Synthesis in India
PA 07 24560

4-(3-((4-((3-Chloro-4-fluorophenyl)(hydroxy)amino)-7-methoxyquinazolin-6-yl)oxy)propyl)morpholine 4-oxide

4-(3-((4-((3-Chloro-4-fluorophenyl)(hydroxy)amino)-7-methoxyquinazolin-6-yl)oxy)propyl)morpholine 4-oxide

  • Catalogue No.:PA 07 24560

  • CAS :

    NA

  • Molecular Formula : C22H24ClFN4O5

  • Molecular Weight : 478.9

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Drug Reference Standards & Impurity Synthesis in India
PA 07 24570

3,4-Dichloroaniline

3,4-Dichloroaniline

  • Catalogue No.:PA 07 24570

  • CAS :

    95-76-1

  • Molecular Formula : C6H5Cl2N

  • Molecular Weight : 162.02

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Drug Reference Standards & Impurity Synthesis in India
PA 07 24580

N-(3-Morpholinopropyl) Gefitinib

N-(3-Morpholinopropyl) Gefitinib

  • Catalogue No.:PA 07 24580

  • CAS :

    1502829-45-9

  • Molecular Formula : C29H37ClFN5O4

  • Molecular Weight : 574.09

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Drug Reference Standards & Impurity Synthesis in India
PA 07 24590

N-(3-Chloro-4-fluorophenyl)-6,7-dimethoxyquinazolin-4-amine

N-(3-Chloro-4-fluorophenyl)-6,7-dimethoxyquinazolin-4-amine

  • Catalogue No.:PA 07 24590

  • CAS :

    153437-78-6

  • Molecular Formula : C16H13ClFN3O2

  • Molecular Weight : 333.74

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Drug Reference Standards & Impurity Synthesis in India
PA 07 24600

N-(4-Fluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine

N-(4-Fluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine

  • Catalogue No.:PA 07 24600

  • CAS :

    2254241-82-0

  • Molecular Formula : C22H25FN4O3

  • Molecular Weight : 412.46

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Drug Reference Standards & Impurity Synthesis in India
PA 07 24610

4-(3-((4-Chloro-7-methoxyquinazolin-6-yl)oxy)propyl)morpholine

4-(3-((4-Chloro-7-methoxyquinazolin-6-yl)oxy)propyl)morpholine

  • Catalogue No.:PA 07 24610

  • CAS :

    199327-59-8

  • Molecular Formula : C16H20ClN3O3

  • Molecular Weight : 337.8

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Drug Reference Standards & Impurity Synthesis in India
PA 07 24620

O-Desmethyl Gefitinib

O-Desmethyl Gefitinib

  • Catalogue No.:PA 07 24620

  • CAS :

    847949-49-9

  • Molecular Formula : C21H22ClFN4O3

  • Molecular Weight : 432.88

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Drug Reference Standards & Impurity Synthesis in India
PA 07 24630

N-(3,4-Difluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine

N-(3,4-Difluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine

  • Catalogue No.:PA 07 24630

  • CAS :

    184475-50-1

  • Molecular Formula : C22H24F2N4O3

  • Molecular Weight : 430.45

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Drug Reference Standards & Impurity Synthesis in India
PA 07 24640

4-Defluoro-4-hydroxy Gefitinib

4-Defluoro-4-hydroxy Gefitinib

  • Catalogue No.:PA 07 24640

  • CAS :

    847949-50-2

  • Molecular Formula : C22H25ClN4O4

  • Molecular Weight : 444.91

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Drug Reference Standards & Impurity Synthesis in India
PA 07 24650

N-(3,4-Dichlorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine

N-(3,4-Dichlorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine

  • Catalogue No.:PA 07 24650

  • CAS :

    2089650-13-3

  • Molecular Formula : C22H24Cl2N4O3

  • Molecular Weight : 463.36

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Drug Reference Standards & Impurity Synthesis in India
PA 07 24660

3-(3-Chloro-4-fluorophenyl)-7-methoxy-4-oxo-3,4-dihydroquinazolin-6-yl Acetate

3-(3-Chloro-4-fluorophenyl)-7-methoxy-4-oxo-3,4-dihydroquinazolin-6-yl Acetate

  • Catalogue No.:PA 07 24660

  • CAS :

    2512211-98-0

  • Molecular Formula : C17H12ClFN2O4

  • Molecular Weight : 362.74

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Drug Reference Standards & Impurity Synthesis in India
PA 07 24670

3-(3-Chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4(3H)-one

3-(3-Chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4(3H)-one

  • Catalogue No.:PA 07 24670

  • CAS :

    1608115-59-8

  • Molecular Formula : C22H23ClFN3O4

  • Molecular Weight : 447.89

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Drug Reference Standards & Impurity Synthesis in India
PA 07 24680

7,8-Dichloro-N-(3-chloro-4-fluorophenyl)-6-(3-morpholinopropoxy)quinazolin-4-amine

7,8-Dichloro-N-(3-chloro-4-fluorophenyl)-6-(3-morpholinopropoxy)quinazolin-4-amine

  • Catalogue No.:PA 07 24680

  • CAS :

    2921918-23-0

  • Molecular Formula : C21H20Cl3FN4O2

  • Molecular Weight : 485.77

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Drug Reference Standards & Impurity Synthesis in India
PA 07 24690

6-Hydroxy-7-methoxy-4(1H)-quinazolinone

6-Hydroxy-7-methoxy-4(1H)-quinazolinone

  • Catalogue No.:PA 07 24690

  • CAS :

    179688-52-9

  • Molecular Formula : C9H8N2O3

  • Molecular Weight : 192.17

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Drug Reference Standards & Impurity Synthesis in India
PA 07 24700

4-Isopropoxy-7-methoxyquinazolin-6-yl acetate

4-Isopropoxy-7-methoxyquinazolin-6-yl acetate

  • Catalogue No.:PA 07 24700

  • CAS :

    NA

  • Molecular Formula : C14H16N2O4

  • Molecular Weight : 276.29

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Drug Reference Standards & Impurity Synthesis in India
PA STI 044040

Gefitinib-d3

Gefitinib-d3

  • Catalogue No.:PA STI 044040

  • CAS :

    1173976-40-3

  • Molecular Formula : C22H21D3ClFN4O3

  • Molecular Weight : 449.92

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Drug Reference Standards & Impurity Synthesis in India
PA IPIPRS 240 12

Gefitinib (IPRS/240/12)-from IPC

Gefitinib (IPRS/240/12)-from IPC

  • Catalogue No.:PA IPIPRS 240 12

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

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Drug Reference Standards & Impurity Synthesis in India
PA EPY0001809

Gefitinib for system suitability (Y0001809)

Gefitinib for system suitability (Y0001809)

  • Catalogue No.:PA EPY0001809

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

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Drug Reference Standards & Impurity Synthesis in India
PA EPY0001813

Gefitinib (Y0001813)

Gefitinib (Y0001813)

  • Catalogue No.:PA EPY0001813

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

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Drug Reference Standards & Impurity Synthesis in India
PA 07 24730

1-(2-amino-4’-methoxy-[1,1’-biphenyl]-4-yl)ethanone

1-(2-amino-4’-methoxy-[1,1’-biphenyl]-4-yl)ethanone

  • Catalogue No.:PA 07 24730

  • CAS :

    246512-44-7

  • Molecular Formula : C15H23N3O4

  • Molecular Weight : 309.36

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Drug Reference Standards & Impurity Synthesis in India
PA 07 24740

2-Amino-4-methoxy-5-[3-(4-morpholinyl)propoxy]benzamide

2-Amino-4-methoxy-5-[3-(4-morpholinyl)propoxy]benzamide

  • Catalogue No.:PA 07 24740

  • CAS :

    1640351-46-7

  • Molecular Formula : C15H22N2O5

  • Molecular Weight : 310.35

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Drug Reference Standards & Impurity Synthesis in India
PA 07 24710

2-Amino-4-methoxy-5-(3-morpholinopropoxy)benzonitrile

2-Amino-4-methoxy-5-(3-morpholinopropoxy)benzonitrile

  • Catalogue No.:PA 07 24710

  • CAS :

    675126-27-9

  • Molecular Formula : C15H21N3O3

  • Molecular Weight : 291.35

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Drug Reference Standards & Impurity Synthesis in India
PA 07 24720

4-Methoxy-5-(3-morpholinopropoxy)-2-nitrobenzonitrile

4-Methoxy-5-(3-morpholinopropoxy)-2-nitrobenzonitrile

  • Catalogue No.:PA 07 24720

  • CAS :

    675126-26-8

  • Molecular Formula : C15H19N3O5

  • Molecular Weight : 321.33

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Drug Reference Standards & Impurity Synthesis in India
PA 07 24750

N'-(2-Cyano-5-methoxy-4-(3-morpholinopropoxy)phenyl)-N,N-dimethylformimidamide

N'-(2-Cyano-5-methoxy-4-(3-morpholinopropoxy)phenyl)-N,N-dimethylformimidamide

  • Catalogue No.:PA 07 24750

  • CAS :

    950596-57-3

  • Molecular Formula : C18H26N4O3

  • Molecular Weight : 346.43

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Drug Reference Standards & Impurity Synthesis in India
PA 07 24760

8-Methoxy-4-oxo-3,4-dihydroquinazolin-7-yl acetate

8-Methoxy-4-oxo-3,4-dihydroquinazolin-7-yl acetate

  • Catalogue No.:PA 07 24760

  • CAS :

    2469273-16-1

  • Molecular Formula : C11H10N2O4

  • Molecular Weight : 234.21

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Drug Reference Standards & Impurity Synthesis in India
PA 07 24770

7-Methoxy-4-oxo-3,4-dihydroquinazolin-8-yl Acetate

7-Methoxy-4-oxo-3,4-dihydroquinazolin-8-yl Acetate

  • Catalogue No.:PA 07 24770

  • CAS :

    NA

  • Molecular Formula : C11H10N2O4

  • Molecular Weight : 234.21

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Drug Reference Standards & Impurity Synthesis in India
PA STI 044041

Gefitinib-d8

Gefitinib-d8

  • Catalogue No.:PA STI 044041

  • CAS :

    857091-32-8

  • Molecular Formula : C22H16D8ClFN4O3

  • Molecular Weight : 454.96

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Drug Reference Standards & Impurity Synthesis in India
PA 07 0241000

4-chloro-7-methoxyquinazolin-6-yl acetate

4-chloro-7-methoxyquinazolin-6-yl acetate

  • Catalogue No.:PA 07 0241000

  • CAS :

    230955-75-6

  • Molecular Formula : C11H9ClN2O3

  • Molecular Weight : 252.65

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Drug Reference Standards & Impurity Synthesis in India
PA 07 0241001

Methyl 2-amino-4-methoxy-5-(3-morpholinopropoxy)benzoate

Methyl 2-amino-4-methoxy-5-(3-morpholinopropoxy)benzoate

  • Catalogue No.:PA 07 0241001

  • CAS :

    214472-41-0

  • Molecular Formula : C16H24N2O5

  • Molecular Weight : 324.38

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Drug Reference Standards & Impurity Synthesis in India
PA 07 0241002

Methyl 4-methoxy-5-(3-morpholinopropoxy)-2-nitrobenzoate

Methyl 4-methoxy-5-(3-morpholinopropoxy)-2-nitrobenzoate

  • Catalogue No.:PA 07 0241002

  • CAS :

    214472-37-4

  • Molecular Formula : C16H22N2O7

  • Molecular Weight : 354.36

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Drug Reference Standards & Impurity Synthesis in India
PA 07 0241003

Gefitinib Nitroso Impurity

Gefitinib Nitroso Impurity

  • Catalogue No.:PA 07 0241003

  • CAS :

    NA

  • Molecular Formula : C22H23ClFN5O4

  • Molecular Weight : 475.91

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Drug Reference Standards & Impurity Synthesis in India
PA STI 089397

Gefitinib-D6

Gefitinib-D6

  • Catalogue No.:PA STI 089397

  • CAS :

    1228664-49-0

  • Molecular Formula : C22H18D6ClFN4O3

  • Molecular Weight : 452.94

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Drug Reference Standards & Impurity Synthesis in India
PA 07 0241004

4-(3-Bromopropyl)morpholine Hydrochloride

4-(3-Bromopropyl)morpholine Hydrochloride

  • Catalogue No.:PA 07 0241004

  • CAS :

    134187-43-2

  • Molecular Formula : C7H15BrClNO

  • Molecular Weight : 244.56

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Drug Reference Standards & Impurity Synthesis in India
PA 07 0241005

4-Hydroxy-7-methoxyquinazolin-6-yl Ester Acetic Acid

4-Hydroxy-7-methoxyquinazolin-6-yl Ester Acetic Acid

  • Catalogue No.:PA 07 0241005

  • CAS :

    179688-53-0

  • Molecular Formula : C11H10N2O4

  • Molecular Weight : 234.21

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Drug Reference Standards & Impurity Synthesis in India
PA 07 0241006

1,3-Dimorpholinopropane

1,3-Dimorpholinopropane

  • Catalogue No.:PA 07 0241006

  • CAS :

    48152-09-6

  • Molecular Formula : C11H22N2O2

  • Molecular Weight : 214.31

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Drug Reference Standards & Impurity Synthesis in India
PA IPRSG017

Gefitinib (IPRSG017)

Gefitinib (IPRSG017)

  • Catalogue No.:PA IPRSG017

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

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Drug Reference Standards & Impurity Synthesis in India
PA 07 0241007

6,7-Dimethoxyquinazolin-4(3H)-one

6,7-Dimethoxyquinazolin-4(3H)-one

  • Catalogue No.:PA 07 0241007

  • CAS :

    13794-72-4

  • Molecular Formula : C10H10N2O3

  • Molecular Weight : 206.2

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Drug Reference Standards & Impurity Synthesis in India
PA 07 0241008

Methyl 2-amino-4,5-dimethoxybenzoate

Methyl 2-amino-4,5-dimethoxybenzoate

  • Catalogue No.:PA 07 0241008

  • CAS :

    26759-46-6

  • Molecular Formula : C10H13NO4

  • Molecular Weight : 211.22

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Drug Reference Standards & Impurity Synthesis in India
PA 07 0241009

2-Chloro-1-fluoro-4-nitrobenzene

2-Chloro-1-fluoro-4-nitrobenzene

  • Catalogue No.:PA 07 0241009

  • CAS :

    350-30-1

  • Molecular Formula : C6H3ClFNO2

  • Molecular Weight : 175.54

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Drug Reference Standards & Impurity Synthesis in India
PA 07 0241010

N-(3-Chloro-2-fluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine

N-(3-Chloro-2-fluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine

  • Catalogue No.:PA 07 0241010

  • CAS :

    909863-33-8

  • Molecular Formula : C22H24ClFN4O3

  • Molecular Weight : 446.91

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Drug Reference Standards & Impurity Synthesis in India
PA 07 0241011

N-(3-Chloro-4-fluorophenyl)-7-methoxy-5-(3-morpholinopropoxy)quinazolin-4-amine

N-(3-Chloro-4-fluorophenyl)-7-methoxy-5-(3-morpholinopropoxy)quinazolin-4-amine

  • Catalogue No.:PA 07 0241011

  • CAS :

    NA

  • Molecular Formula : C22H24ClFN4O3

  • Molecular Weight : 446.91

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