Guanethidine Monosulfate and its Impurities

Guanethidine is an antihypertensive drug that reduces the release of catecholamines, such as norepinephrine. it was once a mainstay for hypertension resistant to other agents, and was often used safely during pregnancy. Reference standards of Guanethidine Monosulfate API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.