halobetasol and its Impurities
Also known in the name of Ulobetasol , it is a corticosteroid which is used to treat inflammation and itching of the skin. Halobetasol is used for treating psoriosis, eczema, insect bites, rashes, allergies, and dermatitis. Reference standards of Halobetasol API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
(6α,11β,16β)-21-Chloro-6,9-difluoro-11-hydroxy-16-methyl-17-(1-oxopropoxy)pregna-1,4-diene-3,20-dione
(6α,11β,16β)-21-Chloro-6,9-difluoro-11-hydroxy-16-methyl-17-(1-oxopropoxy)pregna-1,4-diene-3,20-dione
Catalogue No.:PA 08 01510
CAS :
66852-54-8
Molecular Formula : C25H31ClF2O5
Molecular Weight : 484.96
(6S,8S,9R,10S,11S,13S,14S)-17-(2-Chloroacetyl)-6,9-difluoro-11-hydroxy-10,13,16-trimethyl-6,7,8,9,10,11,12,13,14,15-decahydro-3H-cyclopenta[a]phenanthren-3-one
(6S,8S,9R,10S,11S,13S,14S)-17-(2-Chloroacetyl)-6,9-difluoro-11-hydroxy-10,13,16-trimethyl-6,7,8,9,10,11,12,13,14,15-decahydro-3H-cyclopenta[a]phenanthren-3-one
Catalogue No.:PA 08 0011000
CAS :
NA
Molecular Formula : C22H25ClF2O3
Molecular Weight : 410.89
(6R,9R,11S,16S,17R)-17-(2-Chloroacetyl)-6,9-difluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl propionate
(6R,9R,11S,16S,17R)-17-(2-Chloroacetyl)-6,9-difluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl propionate
Catalogue No.:PA 08 0011001
CAS :
NA
Molecular Formula : C25H31ClF2O5
Molecular Weight : 484.96
(10S,13S,16S,17R)-17-(2-Chloroacetyl)-9-fluoro-11-hydroxy-3-methoxy-10,13,16-trimethyl-2,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl propionate
(10S,13S,16S,17R)-17-(2-Chloroacetyl)-9-fluoro-11-hydroxy-3-methoxy-10,13,16-trimethyl-2,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl propionate
Catalogue No.:PAI 08 001001
CAS :
NA
Molecular Formula : C26H36ClFO5
Molecular Weight : 483.02
1-((9R,10S,13S,16S,17R)-9-Fluoro-11,17-dihydroxy-3-methoxy-10,13,16-trimethyl-8,9,10,11,12,13,14,15,16,17-decahydro-7H-cyclopenta[a]phenanthren-17-yl)-2-hydroxyethan-1-one
1-((9R,10S,13S,16S,17R)-9-Fluoro-11,17-dihydroxy-3-methoxy-10,13,16-trimethyl-8,9,10,11,12,13,14,15,16,17-decahydro-7H-cyclopenta[a]phenanthren-17-yl)-2-hydroxyethan-1-one
Catalogue No.:PAI 08 001002
CAS :
NA
Molecular Formula : C23H31FO5
Molecular Weight : 406.49
2-((4aS,4bS,5aS,6aS,7R,8S,9aS,9bS)-2-(Benzoyloxy)-7-hydroxy-4a,6a,8-trimethyl-4a,5a,6,6a,7,8,9,9a,9b,10-decahydrocyclopenta[1,2]phenanthro[4,4a-b]oxiren-7-yl)-2-oxoethyl benzoate
2-((4aS,4bS,5aS,6aS,7R,8S,9aS,9bS)-2-(Benzoyloxy)-7-hydroxy-4a,6a,8-trimethyl-4a,5a,6,6a,7,8,9,9a,9b,10-decahydrocyclopenta[1,2]phenanthro[4,4a-b]oxiren-7-yl)-2-oxoethyl benzoate
Catalogue No.:PAI 08 001003
CAS :
924726-86-3
Molecular Formula : C36H36O7
Molecular Weight : 580.68
2-((4aS,4bS,5aS,6aS,7R,8S,9aS,9bS,11S)-11-Fluoro-7-hydroxy-4a,6a,8-trimethyl-2-oxo-2,4a,5a,6,6a,7,8,9,9a,9b,10,11-dodecahydrocyclopenta[1,2]phenanthro[4,4a-b]oxiren-7-yl)-2-oxoethyl benzoate
2-((4aS,4bS,5aS,6aS,7R,8S,9aS,9bS,11S)-11-Fluoro-7-hydroxy-4a,6a,8-trimethyl-2-oxo-2,4a,5a,6,6a,7,8,9,9a,9b,10,11-dodecahydrocyclopenta[1,2]phenanthro[4,4a-b]oxiren-7-yl)-2-oxoethyl benzoate
Catalogue No.:PAI 08 001004
CAS :
924726-87-4
Molecular Formula : C29H31FO6
Molecular Weight : 494.56
(4aS,4bS,5aS,6aS,7R,8S,9aS,9bS)-7-(2-Acetoxyacetyl)-7-hydroxy-4a,6a,8-trimethyl-4a,5a,6,6a,7,8,9,9a,9b,10-decahydrocyclopenta[1,2]phenanthro[4,4a-b]oxiren-2-yl benzoate
(4aS,4bS,5aS,6aS,7R,8S,9aS,9bS)-7-(2-Acetoxyacetyl)-7-hydroxy-4a,6a,8-trimethyl-4a,5a,6,6a,7,8,9,9a,9b,10-decahydrocyclopenta[1,2]phenanthro[4,4a-b]oxiren-2-yl benzoate
Catalogue No.:PAI 08 001005
CAS :
182202-37-5
Molecular Formula : C31H34O7
Molecular Weight : 518.61
2-((4aS,4bS,5aS,6aS,7R,8S,9aS,9bS)-11-Fluoro-7-hydroxy-4a,6a,8-trimethyl-2-oxo-2,4a,5a,6,6a,7,8,9,9a,9b,10,11-dodecahydrocyclopenta[1,2]phenanthro[4,4a-b]oxiren-7-yl)-2-oxoethyl acetate
2-((4aS,4bS,5aS,6aS,7R,8S,9aS,9bS)-11-Fluoro-7-hydroxy-4a,6a,8-trimethyl-2-oxo-2,4a,5a,6,6a,7,8,9,9a,9b,10,11-dodecahydrocyclopenta[1,2]phenanthro[4,4a-b]oxiren-7-yl)-2-oxoethyl acetate
Catalogue No.:PAI 08 001006
CAS :
NA
Molecular Formula : C24H29FO6
Molecular Weight : 432.49
(4aS,4bS,5aS,6aS,7R,8S,9aS,9bS,11S)-11-Fluoro-7-hydroxy-7-(2-hydroxyacetyl)-4a,6a,8-trimethyl-5a,6,6a,7,8,9,9a,9b,10,11-decahydrocyclopenta[1,2]phenanthro[4,4a-b]oxiren-2(4aH)-one
(4aS,4bS,5aS,6aS,7R,8S,9aS,9bS,11S)-11-Fluoro-7-hydroxy-7-(2-hydroxyacetyl)-4a,6a,8-trimethyl-5a,6,6a,7,8,9,9a,9b,10,11-decahydrocyclopenta[1,2]phenanthro[4,4a-b]oxiren-2(4aH)-one
Catalogue No.:PAI 08 001007
CAS :
82662-44-0
Molecular Formula : C22H27FO5
Molecular Weight : 390.45
(4aS,4bS,5aS,6aS,7R,8S,9aS,9bS,11S)-7-(2-Chloroacetyl)-11-fluoro-7-hydroxy-4a,6a,8-trimethyl-5a,6,6a,7,8,9,9a,9b,10,11-decahydrocyclopenta[1,2]phenanthro[4,4a-b]oxiren-2(4aH)-one
(4aS,4bS,5aS,6aS,7R,8S,9aS,9bS,11S)-7-(2-Chloroacetyl)-11-fluoro-7-hydroxy-4a,6a,8-trimethyl-5a,6,6a,7,8,9,9a,9b,10,11-decahydrocyclopenta[1,2]phenanthro[4,4a-b]oxiren-2(4aH)-one
Catalogue No.:PAI 08 001008
CAS :
NA
Molecular Formula : C22H26ClFO4
Molecular Weight : 408.89
(6R,8S,9R,10S,11S,13S,14S,16S,17R)-17-(2-Chloroacetyl)-6,9-difluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl propionate
(6R,8S,9R,10S,11S,13S,14S,16S,17R)-17-(2-Chloroacetyl)-6,9-difluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl propionate
Catalogue No.:PA 08 0011002
CAS :
NA
Molecular Formula : C25H31ClF2O5
Molecular Weight : 484.96
