halobetasol propionate and its Impurities
A propionate salt of Halobetasol, which is a a corticosteroid which is used to treat inflammation and itching of the skin like psoriosis, eczema, insect bites, rashes, allergies, and dermatitis. Reference standards of Halobetasol Propionate API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
(4aS,6aS,7R)-2',2'-Diethyl-4a,6a,8-trimethyl-5a,6,6a,8,9,9a,9b,10-octahydro-11H-spiro[cyclopenta[1,2]phenanthro[4,4a-b]oxirene-7,4'-[1,3]dioxane]-2,5'(4aH)-dione
(4aS,6aS,7R)-2',2'-Diethyl-4a,6a,8-trimethyl-5a,6,6a,8,9,9a,9b,10-octahydro-11H-spiro[cyclopenta[1,2]phenanthro[4,4a-b]oxirene-7,4'-[1,3]dioxane]-2,5'(4aH)-dione
Catalogue No.:PAI 08 004010
CAS :
NA
Molecular Formula : C27H36O5
Molecular Weight : 440.58
(4aS,6aS)-7-(2-Hydroxyacetyl)-4a,6a,8-trimethyl-2-oxo-2,4a,5a,6,6a,7,8,9,9a,9b,10,11-dodecahydrocyclopenta[1,2]phenanthro[4,4a-b]oxiren-7-yl propionate
(4aS,6aS)-7-(2-Hydroxyacetyl)-4a,6a,8-trimethyl-2-oxo-2,4a,5a,6,6a,7,8,9,9a,9b,10,11-dodecahydrocyclopenta[1,2]phenanthro[4,4a-b]oxiren-7-yl propionate
Catalogue No.:PAI 08 004020
CAS :
NA
Molecular Formula : C25H32O6
Molecular Weight : 428.53
(4aS,6aS)-4a,6a,8-Trimethyl-7-(2-((methylsulfonyl)oxy)acetyl)-2-oxo-2,4a,5a,6,6a,7,8,9,9a,9b,10,11-dodecahydrocyclopenta[1,2]phenanthro[4,4a-b]oxiren-7-yl Propionate
(4aS,6aS)-4a,6a,8-Trimethyl-7-(2-((methylsulfonyl)oxy)acetyl)-2-oxo-2,4a,5a,6,6a,7,8,9,9a,9b,10,11-dodecahydrocyclopenta[1,2]phenanthro[4,4a-b]oxiren-7-yl Propionate
Catalogue No.:PAI 08 004030
CAS :
NA
Molecular Formula : C26H34O8S
Molecular Weight : 506.61
(4aS,6aS)-7-(2-Chloroacetyl)-4a,6a,8-trimethyl-2-oxo-2,4a,5a,6,6a,7,8,9,9a,9b,10,11-dodecahydrocyclopenta[1,2]phenanthro[4,4a-b]oxiren-7-yl Propionate
(4aS,6aS)-7-(2-Chloroacetyl)-4a,6a,8-trimethyl-2-oxo-2,4a,5a,6,6a,7,8,9,9a,9b,10,11-dodecahydrocyclopenta[1,2]phenanthro[4,4a-b]oxiren-7-yl Propionate
Catalogue No.:PAI 08 004040
CAS :
NA
Molecular Formula : C25H31ClO5
Molecular Weight : 446.97
(4aS,6aS)-2-Acetoxy-7-(2-chloroacetyl)-4a,6a,8-trimethyl-4a,5a,6,6a,7,8,9,9a,9b,10-decahydrocyclopenta[1,2]phenanthro[4,4a-b]oxiren-7-yl Propionate
(4aS,6aS)-2-Acetoxy-7-(2-chloroacetyl)-4a,6a,8-trimethyl-4a,5a,6,6a,7,8,9,9a,9b,10-decahydrocyclopenta[1,2]phenanthro[4,4a-b]oxiren-7-yl Propionate
Catalogue No.:PAI 08 004050
CAS :
NA
Molecular Formula : C27H33ClO6
Molecular Weight : 489.01
(9R,10S,13S)-3-acetoxy-17-(2-Chloroacetyl)-9-fluoro-11-hydroxy-10,13,16-trimethyl-8,9,10,11,12,13,14,15,16,17-decahydro-7H-cyclopenta[a]phenanthren-17-yl Propionate
(9R,10S,13S)-3-acetoxy-17-(2-Chloroacetyl)-9-fluoro-11-hydroxy-10,13,16-trimethyl-8,9,10,11,12,13,14,15,16,17-decahydro-7H-cyclopenta[a]phenanthren-17-yl Propionate
Catalogue No.:PAI 08 004060
CAS :
NA
Molecular Formula : C27H34ClFO6
Molecular Weight : 509.01
(6S,9R,10S,13S)-3-Acetoxy-6-chloro-17-(2-chloroacetyl)-9-fluoro-11-hydroxy-10,13,16-trimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl Propionate
(6S,9R,10S,13S)-3-Acetoxy-6-chloro-17-(2-chloroacetyl)-9-fluoro-11-hydroxy-10,13,16-trimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl Propionate
Catalogue No.:PAI 08 004070
CAS :
NA
Molecular Formula : C27H35Cl2FO6
Molecular Weight : 545.47
(6S,9R,10S,11S,13S,16S,17R)-6-Chloro-9-fluoro-11-hydroxy-10,13,16-trimethyl-17-(2-((methylsulfonyl)oxy)acetyl)-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl Propionate
(6S,9R,10S,11S,13S,16S,17R)-6-Chloro-9-fluoro-11-hydroxy-10,13,16-trimethyl-17-(2-((methylsulfonyl)oxy)acetyl)-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl Propionate
Catalogue No.:PA 08 0261003
CAS :
NA
Molecular Formula : C26H34ClFO8S
Molecular Weight : 561.06
(6S,8S,9R,10S,11S,13S,14S,16S,17R)-9-Chloro-6-fluoro-11-hydroxy-10,13,16-trimethyl-17-(2-((methylsulfonyl)oxy)acetyl)-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl Propionate
(6S,8S,9R,10S,11S,13S,14S,16S,17R)-9-Chloro-6-fluoro-11-hydroxy-10,13,16-trimethyl-17-(2-((methylsulfonyl)oxy)acetyl)-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl Propionate
Catalogue No.:PA 08 0261004
CAS :
NA
Molecular Formula : C26H34ClFO8S
Molecular Weight : 561.06
(6S,8S,9R,10S,11S,13S,14S,16S,17R)-17-(2-Chloroacetyl)-6,9-difluoro-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthrene-11,17-diyl dipropionate
(6S,8S,9R,10S,11S,13S,14S,16S,17R)-17-(2-Chloroacetyl)-6,9-difluoro-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthrene-11,17-diyl dipropionate
Catalogue No.:PAI 08 004072
CAS :
886204-51-9
Molecular Formula : C28H35ClF2O6
Molecular Weight : 541.04
(8S,9R,10S,11S,13S,14S,16S,17R)-6,9-Difluoro-11-hydroxy-2',2',10,13,16-pentamethyl-7,8,9,10,11,12,13,14,15,16-decahydrospiro[cyclopenta[a]phenanthrene-17,4'-[1,3]dioxane]-3,5'(6H)-dione
(8S,9R,10S,11S,13S,14S,16S,17R)-6,9-Difluoro-11-hydroxy-2',2',10,13,16-pentamethyl-7,8,9,10,11,12,13,14,15,16-decahydrospiro[cyclopenta[a]phenanthrene-17,4'-[1,3]dioxane]-3,5'(6H)-dione
Catalogue No.:PAI 08 004073
CAS :
NA
Molecular Formula : C25H32F2O5
Molecular Weight : 450.52
(8S,9R,10S,11S,13S,14S,16S,17R)-6,9-Difluoro-2',2',10,13,16-pentamethyl-3,5'-dioxo-3,6,7,8,9,10,11,12,13,14,15,16-dodecahydrospiro[cyclopenta[a]phenanthrene-17,4'-[1,3]dioxan]-11-yl propionate
(8S,9R,10S,11S,13S,14S,16S,17R)-6,9-Difluoro-2',2',10,13,16-pentamethyl-3,5'-dioxo-3,6,7,8,9,10,11,12,13,14,15,16-dodecahydrospiro[cyclopenta[a]phenanthrene-17,4'-[1,3]dioxan]-11-yl propionate
Catalogue No.:PAI 08 004074
CAS :
NA
Molecular Formula : C28H36F2O6
Molecular Weight : 506.59
(6S,8S,9R,10S,11S,13S,14S,16S,17R)-6,9-Difluoro-17-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-11-yl propionate
(6S,8S,9R,10S,11S,13S,14S,16S,17R)-6,9-Difluoro-17-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-11-yl propionate
Catalogue No.:PAI 08 004075
CAS :
NA
Molecular Formula : C25H32F2O6
Molecular Weight : 466.52
(10S,13S,16S,17R)-2-Chloro-17-(2-chloroacetyl)-9-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl propionate
(10S,13S,16S,17R)-2-Chloro-17-(2-chloroacetyl)-9-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl propionate
Catalogue No.:PA 08 0261007
CAS :
NA
Molecular Formula : C25H31Cl2FO5
Molecular Weight : 501.42
